Jingyuan Yu, Xueyan Wei^*, Jinghui Wang

International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1929-1948, 2025, DOI:10.32604/ijmhp.2025.071233 - 31 December 2025

Abstract Background: Chinese elementary students face mental health challenges due to excessive academic pressures. Previous research has indicated that resilience is crucial for improving their mental health, which is fostered by a supportive family environment. This study, therefore, explored the impact of family organization on children’s resilience and examined whether proactive coping and mindfulness mediate this relationship. Methods: Data were collected from 702 elementary school students (grades 3–6) in 3 cities in China using a multi-stage sampling procedure. Validated scales measured family organization, proactive coping, mindfulness, and resilience. The hypothesized model was tested using Structural Equation Modeling… More >

Wenxiang Zhang^1,2, Wenning Cui¹, Juan Huang³, Zhangen Lu¹, Kuijing Liang¹, Lingbao Wang^1,2, Shanshan Wei^1,2, Liran Shi¹, Huifen Li¹, Xiaoli Guo^1,2,*, Jianhui Ma^4,*

Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3893-3912, 2025, DOI:10.32604/phyton.2025.073736 - 29 December 2025

Abstract UDP-glycosyltransferases (UGTs) play essential roles in plant secondary metabolism and stress responses, yet their composition and functions in Sorghum bicolor, a model C4 plant, remain inadequately characterized. This study identified 196 SbUGT genes distributed across all 10 chromosomes and classified them into 16 subfamilies (A–P) through phylogenetic analysis. Among these, 61.2% were intronless, and 10 conserved motifs, including the UGT-specific PSPG box, were identified. Synteny analysis using MCScanX revealed 12 segmental duplication events and conserved syntenic relationships with other Poaceae species (rice, maize, and barley). Promoter analysis uncovered 125 distinct cis-acting elements, predominantly associated with stress and… More >

Wenjie Qiu¹, Jiyuan Wang², Zheng Zhang^3,*

Journal of Psychology in Africa, Vol.35, No.6, pp. 815-823, 2025, DOI:10.32604/jpa.2025.070151 - 30 December 2025

Abstract This study examined emotional exhaustion and family support in the relationship between leader workaholism and employee work fatigue. The participants were 408 employed adults (74% female, age range 25 to 27 years) across five industries: sales (31.65%), finance (25.32%), education (20.25%), public administration (12.66%), and technology (10.13%), from 79 work teams in China. Survey data were collected at three time points over a three-month period. The results from structural equation modeling indicated that leader workaholism was associated with higher employee work fatigue. Emotional exhaustion mediated the relationship, contributing to higher levels of employee fatigue. Furthermore, More >

Ioannis A. Voutsadakis^1,2,3,*

Oncology Research, Vol.33, No.12, pp. 4073-4092, 2025, DOI:10.32604/or.2025.069230 - 27 November 2025

Abstract Background: E26 transformation-specific (ETS) family transcription factors have confirmed roles in several types of cancers. This study aimed to clarify the role of ETS family transcription factor alterations in gastric cancers. Methods: This study examines molecular alterations of ETS transcription factors in gastric adenocarcinomas based on an analysis of publicly available cohorts from the Protein Atlas and the Cancer Genome Atlas. The expression and relationships of members of the ETS transcription factor family with other important factors in the process of gastric carcinogenesis were evaluated using the same resources. Results: mRNA expression levels of ETS family… More >

Xinke Chai, Shifeng Wu, Qian Shen, Qiulin Huang^*

Oncology Research, Vol.33, No.12, pp. 3731-3752, 2025, DOI:10.32604/or.2025.067546 - 27 November 2025

Abstract Gastric cancer (GC) is a prevalent malignant tumor globally, with high incidence and mortality rates. Advances in understanding molecular mechanisms underlying GC have highlighted the role of microRNAs (miRNAs) in its initiation, progression, and treatment. The Let-7 family, an important class of miRNAs, is closely associated with the biological behaviors of GC. Aberrant expression of various Let-7 family members in GC patients contributes to disease progression, as they target multiple molecular pathways and participate in diverse regulatory mechanisms throughout GC pathogenesis. This article systematically summarizes the expression patterns of Let-7 family members in GC, explores More >

Mingxin Zhong^1,#, Yuanyuan Zhang^1,#, Xinlei Guo¹, Bainian Zhang², Chengjia Tan¹, Zhuo Xu¹, Xin Hu¹, Daren Feng³, Zhenpeng Xi⁴, Qian Wang^1,*, Hui Tian^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3061-3084, 2025, DOI:10.32604/phyton.2025.070560 - 29 October 2025

Abstract Magnolia officinalis is a perennial deciduous tree that has medicinal properties. The AP2/ERF gene family has a number of roles in long-term growth and metabolism. The expression of this function varies with the growth period. In this work, based on the transcriptome data of Magnolia officinalis, the complete coding gene of Magnolia officinalis was obtained, and the corresponding protein sequence was retrieved from NCBI and compared with the model plant Arabidopsis thaliana. After screening, 75 protein sequences from the AP2/ERF gene family were identified and called MoAP2/ERF1–MoAP2/ERF75, followed by bioinformatics analysis. 75 AP2/ERF gene families were found and classified into four… More >

Abdil Hakan Eren^*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3085-3107, 2025, DOI:10.32604/phyton.2025.069506 - 29 October 2025

Abstract The FAR1-related sequence (FAR1) gene family consists of transcription factors that originated from transposases and is crucial for light signaling and stress adaptation in plants. Despite the recognized importance of FAR1 genes in model organisms, their genomic architecture, structural variability, and expression patterns in Phaseolus vulgaris have yet to be investigated. This study offers the inaugural comprehensive genome-wide identification and characterization of the FAR1 gene family in P. vulgaris. A total of 27 PvulFAR1 genes were identified, and their chromosomal distribution, gene structures, conserved domains, and phylogenetic relationships were analyzed systematically. The promoter regions of these genes were discovered… More >

Ruiqian Li^1,*, Peibing Zheng¹, Mengxin Yan¹, Xinyi Zhou², Ziyu Wu¹, Yiting Wang¹

Journal of Psychology in Africa, Vol.35, No.5, pp. 681-688, 2025, DOI:10.32604/jpa.2025.069421 - 24 October 2025

Abstract This study examined the relationship between paternal overprotective parenting and problem behaviors of preschool children, and maternal overprotective attitudes and parenting stress mediation of that relationship. Data were collected from 265 families, including parents and preschool children (ages 3–6). The results revealed that paternal overprotective attitudes significantly influenced maternal overprotective attitudes and maternal parenting stress. Maternal overprotective attitudes, in turn, increased maternal parenting stress, exacerbated children’s problem behaviors. Paternal overprotective attitudes indirectly contributed to these behaviors through both maternal overprotective attitudes and parenting stress. The effect was more pronounced on boy than girl younger than More >

Jiaqi Lu¹, Fang Wang^2,*

Journal of Psychology in Africa, Vol.35, No.5, pp. 651-659, 2025, DOI:10.32604/jpa.2025.066088 - 24 October 2025

Abstract This study explores parenting and family adjustment profile effects on toddler socioemotional competence by the underlying mechanisms of effortful control. Participants were Chinese parent caregivers (N = 448) of 448 toddlers aged 15–36 months. They completed measures of parenting and family adjustment, toddler socioemotional competence, and effortful control. Latent profile analysis (LPA) identified three family profiles—Strict-Detached, Constrained-Collaborative, and Harmonious-Aligned. These three profiles of parenting and family adjustment directly affect toddler socioemotional competence through variations in emotional support, discipline strategies, and parent–child interactions. Effortful control mediates this relationship of parenting and family adjustment and toddler socioemotional More >

Sihai Duan^1,2,#, Xiaoyan Li^3,#, Cailu Song³, Song Wu³, Yunyun Tang^3,4, Qing Bao^3,4, Na Li^3,*, Hailin Tang^3,*

Oncology Research, Vol.33, No.11, pp. 3543-3556, 2025, DOI:10.32604/or.2025.068292 - 22 October 2025

Abstract Objectives: Triple-negative breast cancer (TNBC) is the breast cancer subtype with the poorest prognosis. This study aimed to elucidate the molecular pathways through which isoliquiritigenin (ISL), a natural chalcone compound derived from licorice and other plant roots, targets interferon regulatory factor 5 (IRF5) in TNBC. Methods: TNBC cell lines were cultured and subjected to IRF5 knockdown using short hairpin RNA. Cell proliferation was assessed by cell counting kit-8 (CCK-8) assay and colony formation assays. Western blotting and quantitative reverse transcription polymerase chain reaction (RT-PCR) were employed to measure expression levels of IRF5, solute carrier family… More >