Aike Qiao^1,*, Honghui Zhang¹, Jun Xia¹

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 35-35, 2019, DOI:10.32604/mcb.2019.05715

Abstract In order to improve the calculation accuracy of computed tomography angiography-derived fractional flow reserve (FFR_CT), a mathematical model for setting the patient-specific flow boundary condition was proposed, in which some independent physiological parameters, such as myocardial mass, diastolic blood pressure, heart rate and vessel volume were considered. This model was employed to simulate hemodynamics in sixteen patients with coronary stenosis. The results of FFR_CT demonstrated good consistency with invasively measured FFR. The diagnostic accuracy of FFR_CT was 85%. The proposed model offers a new approach to improve the accuracy of FFR_CT, as well as promotes the clinical application of FFR_CT. More >

Mingge Wu¹, Lei Wang¹, Yixiang Wang¹, Cheng Zhang¹, Cheng Qiu^{1, 2, *}

FDMP-Fluid Dynamics & Materials Processing, Vol.15, No.4, pp. 431-444, 2019, DOI:10.32604/fdmp.2019.08209

Abstract Water management in proton exchange membrane fuel cells (PEMFC) is a topic of great importance for the optimization of these systems. Effective proton conductivity calls for moderate moisture content in the membrane, while uneven water distribution can lead to instability of the whole flow field, thereby decreasing the performance of the fuel cell. In the present study, a simplified two-tier hybrid structure is used to investigate the impact of the dynamic behavior of liquid water on the current density of the PEMFC. Simulation results show that water droplets attached to wall sides tend to increase current density. Visualization experiments confirm… More >

Sangho Kim^∗,†, Peng Kai Ong^*, Paul C. Johnson^‡

Molecular & Cellular Biomechanics, Vol.6, No.2, pp. 83-92, 2009, DOI:10.3970/mcb.2009.006.083

Abstract Recently, we reported that collision efficiency (fraction of total collisions that result in the formation of aggregates) between red blood cells was an important factor in the formation of aggregates in postcapillary venules. In the present study, we focus on how high molecular weight dextran influences the overall radial migration trend of red blood cells in the postcapillary venule along a longitudinal distance of 50 μm from the bifurcation which would in turn affect collision behavior of these cells. A radial migration index, which defines the extent of radial migration of individual cells relative to the vessel center, was found… More >