Rabindranath Bera^1,#, Yotaro Ochi^2,3, Ying-Jung Huang¹, Ming-Chung Kuo^1,4, Kenichi Yoshida⁵, Seishi Ogawa², Lee-Yung Shih^1,4,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070259 - 30 December 2025

Abstract Background: Breakpoint Cluster Region-Abelson (BCR::ABL1) fusion protein is essential in the pathogenesis of chronic myeloid leukemia (CML); however, the chronic-to-blast phase transformation remains elusive. We identified novel kinesin light chain 2 (KLC2) mutations in CML-myeloid blast phase patients. We aimed to examine the functional role of KLC2 mutations in leukemogenesis. Methods: To evaluate the biological role of KLC2 mutants (MT) in CML cells, we expressed KLC2-MT in different human CML cell lines harboring BCR::ABL1 and performed immunoblot, immunofluorescence, cell proliferation, differentiation, and apoptosis; Tyrosine kinase inhibitor (TKI)-drug activities; and clonogenic assays for in vitro functional analyses. We co-expressed KLC2-MT… More >

Junwen Huo, Haicheng Liang, Weiye Dong, Xiaoming Du^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-20, 2026, DOI:10.32604/cmc.2025.073285 - 09 December 2025

Abstract With the rapid advancement of electromagnetic launch technology, enhancing the structural stability and thermal resistance of armatures has become essential for improving the overall efficiency and reliability of railgun systems. Traditional aluminum alloy armatures often suffer from severe ablation, deformation, and uneven current distribution under high pulsed currents, which limit their performance and service life. To address these challenges, this study employs the Johnson–Cook constitutive model and the finite element method to develop armature models of aluminum matrix composites with varying heterogeneous graphene volume fractions. The temperature, stress, and strain of the armatures during operation… More >

Siwen Xu¹, Hanning Chen², Rui Ni¹, Maowei He², Zhaodi Ge³, Xiaodan Liang^2,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-25, 2026, DOI:10.32604/cmc.2025.071398 - 09 December 2025

Abstract Selective Laser Melting (SLM), an advanced metal additive manufacturing technology, offers high precision and personalized customization advantages. However, selecting reasonable SLM parameters is challenging due to complex relationships. This study proposes a method for identifying the optimal process window by combining the simulation model with an optimization algorithm. JAYA is guided by the principle of preferential behavior towards best solutions and avoidance of worst ones, but it is prone to premature convergence thus leading to insufficient global search. To overcome limitations, this research proposes a Differential Evolution-framed JAYA algorithm (DEJAYA). DEJAYA incorporates four key enhancements More >

Jiajia Liu^1,*, Junyi Lin², Wenxiang Dong², Xuan Zhao², Jianhua Liu², Huiru Li³

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.071397 - 09 December 2025

Abstract Single Image Super-Resolution (SISR) seeks to reconstruct high-resolution (HR) images from low-resolution (LR) inputs, thereby enhancing visual fidelity and the perception of fine details. While Transformer-based models—such as SwinIR, Restormer, and HAT—have recently achieved impressive results in super-resolution tasks by capturing global contextual information, these methods often suffer from substantial computational and memory overhead, which limits their deployment on resource-constrained edge devices. To address these challenges, we propose a novel lightweight super-resolution network, termed Binary Attention-Guided Information Distillation (BAID), which integrates frequency-aware modeling with a binary attention mechanism to significantly reduce computational complexity and parameter… More >

Sabina-Cristiana Necula^*, Napoleon-Alexandru Sireteanu

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-34, 2026, DOI:10.32604/cmc.2025.070861 - 09 December 2025

Abstract Modern business information systems face significant challenges in managing heterogeneous data sources, integrating disparate systems, and providing real-time decision support in complex enterprise environments. Contemporary enterprises typically operate 200+ interconnected systems, with research indicating that 52% of organizations manage three or more enterprise content management systems, creating information silos that reduce operational efficiency by up to 35%. While attention mechanisms have demonstrated remarkable success in natural language processing and computer vision, their systematic application to business information systems remains largely unexplored. This paper presents the theoretical foundation for a Hierarchical Attention-Based Business Information System (HABIS)… More >

Le Wang¹, Bing Xu^1,*, Peng Liu², En Yuan¹

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-14, 2026, DOI:10.32604/cmc.2025.070794 - 09 December 2025

Abstract Deep learning has been recognized as an effective method for indoor positioning. However, most existing real-valued neural networks (RVNNs) treat the two constituent components of complex-valued channel state information (CSI) as real-valued inputs, potentially discarding useful information embedded in the original CSI. In addition, existing positioning models generally face the contradiction between computational complexity and positioning accuracy. To address these issues, we combine graph neural network (GNN) with complex-valued neural network (CVNN) to construct a lightweight indoor positioning model named CGNet. CGNet employs complex-valued convolution operation to directly process the original CSI data, fully exploiting… More >

Yi Cao¹, Kuo Zhang¹, Chengsheng Yuan^2,*, Linglong Zhu¹, Wentao Ge²

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-24, 2026, DOI:10.32604/cmc.2025.070158 - 09 December 2025

Abstract Generative steganography uses generative stego images to transmit secret message. It also effectively defends against statistical steganalysis. However, most existing methods focus primarily on matching the feature distribution of training data, often neglecting the sequential continuity between moves in the game. This oversight can result in unnatural patterns that deviate from real user behavior, thereby reducing the security of the hidden communication. To address this issue, we design a Gomoku agent based on the AlphaZero algorithm. The model engages in self-play to generate a sequence of plausible moves. These moves form the basis of the… More >

Illia Khurtin^*, Mukesh Prasad

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-15, 2026, DOI:10.32604/cmc.2025.067481 - 09 December 2025

Abstract The field of artificial intelligence has advanced significantly in recent years, but achieving a human-like or Artificial General Intelligence (AGI) remains a theoretical challenge. One hypothesis suggests that a key issue is the formalisation of extracting meaning from information. Meaning emerges through a three-stage interpretative process, where the spectrum of possible interpretations is collapsed into a singular outcome by a particular context. However, this approach currently lacks practical grounding. In this research, we developed a model based on contexts, which applies interpretation principles to the visual information to address this gap. The field of computer… More >

Binglei Yue, Aili Jiang, Chun Yang, Junwei Lei, Heng Liu, Yin Zhang^*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-28, 2026, DOI:10.32604/cmc.2025.071047 - 10 November 2025

Abstract With the growing advancement of wireless communication technologies, WiFi-based human sensing has gained increasing attention as a non-intrusive and device-free solution. Among the available signal types, Channel State Information (CSI) offers fine-grained temporal, frequency, and spatial insights into multipath propagation, making it a crucial data source for human-centric sensing. Recently, the integration of deep learning has significantly improved the robustness and automation of feature extraction from CSI in complex environments. This paper provides a comprehensive review of deep learning-enhanced human sensing based on CSI. We first outline mainstream CSI acquisition tools and their hardware specifications, More >

Sunbin Shin¹, Luong Vuong Nguyen², Grzegorz J. Nalepa^3,4, Paulo Novais⁵, Xuan Hau Pham⁶, Jason J. Jung^1,*

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-40, 2026, DOI:10.32604/cmc.2025.070613 - 10 November 2025

Abstract Recommending personalized travel routes from sparse, implicit feedback poses a significant challenge, as conventional systems often struggle with information overload and fail to capture the complex, sequential nature of user preferences. To address this, we propose a Conditional Generative Adversarial Network (CGAN) that generates diverse and highly relevant itineraries. Our approach begins by constructing a conditional vector that encapsulates a user’s profile. This vector uniquely fuses embeddings from a Heterogeneous Information Network (HIN) to model complex user-place-route relationships, a Recurrent Neural Network (RNN) to capture sequential path dynamics, and Neural Collaborative Filtering (NCF) to incorporate… More >