Arham Adnan¹, Muhammad Tuaha Rizwan¹, Hafiz Muhammad Attaullah^1,2,*, Shakila Basheer³, Mohammad Tabrez Quasim⁴

CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5073-5091, 2025, DOI:10.32604/cmc.2025.068797 - 23 October 2025

Abstract Artificial intelligence (AI), particularly deep learning algorithms utilizing convolutional neural networks, plays an increasingly pivotal role in enhancing medical image examination. It demonstrates the potential for improving diagnostic accuracy within dental care. Orthopantomograms (OPGs) are essential in dentistry; however, their manual interpretation is often inconsistent and tedious. To the best of our knowledge, this is the first comprehensive application of YOLOv5m for the simultaneous detection and classification of six distinct dental pathologies using panoramic OPG images. The model was trained and refined on a custom dataset that began with 232 panoramic radiographs and was later… More >

Sotirios Charalampos Diamantoudis^1,#,*, Androulla N. Miliotou^2,#, Eleftheria Galatou², Stergiani Telliou³, Konstantinos Sideris⁴, Nikolaos Grigoriadis¹, Ioannis S. Vizirianakis^1,2,*

BIOCELL, Vol.49, No.10, pp. 1799-1858, 2025, DOI:10.32604/biocell.2025.067216 - 22 October 2025

Abstract Hematological cancer stem cells (HCSCs) is a subpopulation of cells within hematological cancers that, through their characteristics, enhance malignancy and render their therapy more challenging. By uncovering the underlying mechanisms behind characteristic properties such as self-renewal, immune evasion, and conventional therapy resistance, as well as the major differences between other cancers and physiological cells, new and alternative targets can be assessed for use in existing and novel immunotherapeutic interventions. Through the evaluation of the existing literature, one can realize that there have already been several studies addressing the use of stem cell transplantation (SCT), monoclonal More > Graphic Abstract

Sophia Strukel¹, Vikrant Rai^1,2,*

BIOCELL, Vol.49, No.10, pp. 1887-1911, 2025, DOI:10.32604/biocell.2025.067207 - 22 October 2025

Abstract Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus and are associated with high morbidity, risk of amputation, and increased mortality. Although DFUs typically remain a chronic, non-healing wound, a small portion of DFUs may undergo malignant transformation. The subsequent malignancies are skin cancers such as squamous cell carcinoma (SCC), basal cell carcinoma, or melanoma. Understanding the pathophysiology of DFUs and the molecular and clinical determinants that contribute to their potential malignant transformation if crucial for clinical management. Chronic inflammation, dysregulation of cytokine signaling, faulty immune surveillance, and impaired wound healing all play… More >

Anjali Kariyarath Valappil^1,#, Reshmi Akter^2,#, Muhammad Awais², Dong Uk Yang³, Daehyo Jung², Li Ling⁴, Eun Kim⁵, Kyu Hyeong Yoon⁵, Yoon Ok Lee⁵, Deok Chun Yang^1,2,4,*

BIOCELL, Vol.49, No.9, pp. 1771-1795, 2025, DOI:10.32604/biocell.2025.069145 - 25 September 2025

Abstract Objectives: The phytochemical investigation of traditional herbal medicines holds significant promise for modern drug discovery, particularly in cancer therapy. This study aimed to evaluate the cytotoxicity, apoptosis induction, and immune-modulatory activities of extracts from three herbal medicines with historical use in traditional medicine—Acanthopanax sessiliflorus, Phragmites communis, and Pinus densiflora, as well as their combined extract (GMAS 01/COM), on human lung cancer cells (A549) and normal cell lines, including murine macrophages (RAW 264.7) and human keratinocytes (HaCaT). Methods: Plant extracts were prepared using aqueous extraction, sonication, and rotary evaporation. The total phenolic and flavonoid contents were quantified using the… More >

Zesheng Xi^1,2,#, Chuan He^1,3,#, Yunfan Wang^1,3,#, Bo Zhang^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2545-2565, 2025, DOI:10.32604/cmes.2025.066822 - 31 August 2025

Abstract The increasing reliance on interconnected Internet of Things (IoT) devices has amplified the demand for robust anonymization strategies to protect device identities and ensure secure communication. However, traditional anonymization methods for IoT networks often rely on static identity models, making them vulnerable to inference attacks through long-term observation. Moreover, these methods tend to sacrifice data availability to protect privacy, limiting their practicality in real-world applications. To overcome these limitations, we propose a dynamic device identity anonymization framework using Moving Target Defense (MTD) principles implemented via Software-Defined Networking (SDN). In our model, the SDN controller periodically… More >

Wenqin Chen¹, Yuting Wen², Chen Hong³, Nan Ma⁴, Wenting Yi⁵, Guiliang Peng⁶, Yanyan Hu^7,*, Yang He^3,*

Journal of Psychology in Africa, Vol.35, No.3, pp. 419-427, 2025, DOI:10.32604/jpa.2025.068039 - 31 July 2025

Abstract This study tested a chain mediation model on whether hopelessness and nostalgia play a mediating role in psychache and suicidal ideation of firefighters. A total of 652 firefighters participated in the survey (male = 94.94%; mean age = 23.71 years, SD = 4.18 years). The firefighters completed the Chinese Revised Psychache Scale (PAS), Beck Hopelessness Scale (BHS), Southampton Nostalgia Scale (SNS), and Columbia-Suicide Severity Rating Scale (C-SSRS). The path analysis results indicated that psychache positively predicted suicidal ideation. Hopelessness plays a significant mediating role between psychache and suicidal ideation further strengthening this relationship. In contrast, More >

Shuai Zhang¹, Xin Lai^1,*, Haiyan Niu², Lisheng Liu^1,3, Shifu Wang², Jinyong Zhang³

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.1, pp. 739-762, 2025, DOI:10.32604/cmes.2025.067442 - 31 July 2025

Abstract This study investigates the dynamic compressive behavior of three periodic lattice structures fabricated from Ti-6Al-4V titanium alloy, each with distinct topologies: simple cubic (SC), body-centered cubic (BCC), and face-centered cubic (FCC). Dynamic compression experiments were conducted using a Split Hopkinson Pressure Bar (SHPB) system, complemented by high-speed imaging to capture real-time deformation and failure mechanisms under impact loading. The influence of cell topology, relative density, and strain rate on dynamic mechanical properties, failure behavior, and stress wave propagation was systematically examined. Finite element modeling was performed, and the simulated results showed good agreement with experimental… More >

Bo Li, Xiaoying Yang^*, Zhijie Pei, Xin Yang, Yaqi Wu

CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 3649-3672, 2025, DOI:10.32604/cmc.2025.066267 - 03 July 2025

Abstract It is well known that the kit completeness of parts processed in the previous stage is crucial for the subsequent manufacturing stage. This paper studies the flexible job shop scheduling problem (FJSP) with the objective of material kitting, where a material kit is a collection of components that ensures that a batch of components can be ready at the same time during the product assembly process. In this study, we consider completion time variance and maximum completion time as scheduling objectives, continue the weighted summation process for multiple objectives, and design adaptive weighted summation parameters… More >

Yuan Zou¹, Chao Lu^1,*, Lvjiang Yin², Xiaoyu Wen³

CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 2305-2330, 2025, DOI:10.32604/cmc.2025.065972 - 03 July 2025

Abstract The shop scheduling problem with limited buffers has broad applications in real-world production scenarios, so this research direction is of great practical significance. However, there is currently little research on the hybrid flow shop scheduling problem with limited buffers (LBHFSP). This paper deeply investigates the LBHFSP to optimize the goal of the total completion time. To better solve the LBHFSP, a multi-level subpopulation-based particle swarm optimization algorithm (MLPSO) is proposed, which is founded on the attributes of the LBHFSP and the shortcomings of the basic PSO (particle swarm optimization) algorithm. In MLPSO, firstly, considering the… More >

Cesar E. Montelongo Hernandez^1,*, Carol S. North¹, E. Whitney Pollio², David E. Pollio³

International Journal of Mental Health Promotion, Vol.27, No.6, pp. 737-752, 2025, DOI:10.32604/ijmhp.2025.065317 - 30 June 2025

Abstract Background: Disaster mental health outcomes of individuals may be affected by the families they inhabit, with effects rippling through the entire family system. Existing research on the experience of children in disasters has typically been limited to examining single individuals or, at most, family dyads. Research is needed to explore interactions within families as a whole, including interactions among multiple family members, as well as with community entities in a broad systems approach with dynamic analysis of family systems over time. The purpose of this study was to combine quantitative and qualitative data using structured… More >