Jie Wu^1,#, Guiwen Liang^1,#, Ya Pan^1,#, Talaibaike Maimaijuma^2,3, Xianggui Xu^2,3, Juying Lu¹, Zhongwei Huang^1,*, Lei Qi^1,*, Haiyan Jiang^1,*

Structural and Congenital Heart Disease, Vol.21, No.2, 2026, DOI:10.32604/schd.2026.077080 - 11 June 2026

Abstract Background: Children with congenital heart disease (CHD) complicated by severe infection often present with immature immune function and poor prognosis. Evidence supporting the use of glucocorticoids in this population, particularly with dynamic immune monitoring, remains limited. Methods: A retrospective analysis was conducted on 183 CHD children with severe infections admitted to the Pediatric Intensive Care Unit (PICU) from 2019 to 2023. Patients were divided into two groups: the glucocorticoid intervention group (n = 92, methylprednisolone + standard treatment) and the control group (n = 91, standard treatment). Immune indicators (Interleukins-6 (IL-6), C-reactive protein (CRP), procalcitonin (PCT), CD4⁺/CD8⁺ ratio… More >

Shanhong Luo¹, Hongjuan Xu^2,*

Canadian Journal of Urology, Vol.33, No.2, pp. 417-426, 2026, DOI:10.32604/cju.2025.069884 - 20 April 2026

Abstract Background: Early detection and timely treatment of urinary tract infections (UTIs) can prevent the aggravation of the inflammatory response following a stroke and enhance the recovery of neurological function. This study aimed to develop a simple scoring system by integrating nutritional and inflammatory markers to predict the occurrence of UTIs in patients with acute stroke. Methods: Reviews of 1011 patients with acute stroke were retrieved. The Geriatric Nutritional Risk Index (GNRI) and systemic inflammation response index (SIRI) were utilized to develop a composite score of nutritional-systemic inflammation response index (G-SIRI). The primary endpoint was the… More >

Kai Dang^1,2,#, Teng Cui^1,2,#, Yongan Zhou^1,2, Jiayuan Ji^1,2, Yang Yang^1,2, Xiangyu Wang^1,2, Jing Xiao^1,2,*

Canadian Journal of Urology, Vol.33, No.2, pp. 403-415, 2026, DOI:10.32604/cju.2026.068291 - 20 April 2026

Abstract Objectives: Although renal colic is a well-known acute manifestation of urolithiasis, the relationship between its pain severity and a range of clinical parameters has not been clearly established by comprehensive studies. This study aimed to construct and validate a simple and accurate clinical nomogram for predicting the occurrence of more intense acute renal colic (ARC) in patients with urolithiasis. Methods: The development and validation of the prediction model followed the reporting standards outlined in the TRIPOD checklist. A retrospective analysis was conducted on 285 patients who visited the Department of Urology at Beijing Friendship Hospital,… More >

Sugey Vásquez-Hernández, Joaquín Adolfo Montes-Molina^*, Federico Antonio Gutierrez-Miceli, Nancy Ruiz-Lau, Victor Manuel Ruiz-Valdiviezo, Carlos Alberto Lecona-Guzmán^*

Phyton-International Journal of Experimental Botany, Vol.95, No.3, 2026, DOI:10.32604/phyton.2026.076451 - 31 March 2026

Abstract Agave americana L. is potentially a source of functional and nutritive compounds. However, its yield has been compromised by vascular wilt, which is associated with the presence of the Fusarium oxysporum. In response to this phytosanitary problem, the implementation of efficient methods to mitigate the damage. Biotechnological techniques offer a viable alternative to improve and increase the production of species of interest via genetic improvement. By use of mutagenic chemical agents, these techniques have been consolidated as a powerful tool to induce genetic variability and select genotypes with greater tolerance to pathogens. In this study, we evaluated… More >

Abdelkader Akkad, Franck Bruyere, Ali Bourgi^*

Canadian Journal of Urology, Vol.33, No.1, pp. 155-163, 2026, DOI:10.32604/cju.2025.069546 - 28 February 2026

Abstract Objectives: Uretero-enteric strictures are feared complications following cystectomy. Despite surgical advancements, particularly the rise of robot-assisted approaches, the risk factors associated with these strictures remain poorly defined. This study aimed to identify the risk factors associated with uretero-enteric anastomotic strictures after cystectomy, according to the surgical approach and type of urinary diversion (extracorporeal vs. intracorporeal). Methods: We conducted a single-center retrospective study including 340 patients who underwent cystectomy between 2016 and 2024 at Tours University Hospital. Clinical, biological, perioperative, and postoperative data were analyzed. The occurrence of a uretero-ileal anastomotic stricture was defined radiologically by… More >

Guido Carloni, Monica Rinaldi^*

Oncology Research, Vol.34, No.3, 2026, DOI:10.32604/or.2025.071847 - 24 February 2026

Abstract Hepatitis C virus (HCV) and hepatitis B virus (HBV) infections are increasingly recognized as significant etiological factors in the pathogenesis of B-cell non-Hodgkin’s lymphomas (B-NHLs). Epidemiological and molecular studies have demonstrated a consistent association between chronic viral infection and B-NHLs. Multiple pathogenic mechanisms have been implicated in lymphomagenesis, both direct and indirect, including chronic antigenic stimulation, direct infection of B cells, and viral protein–mediated oncogenic signaling, It is likely that a combination of several pathogenic conditions is required to eventually lead to the development of lymphoma. The prevalence of B-cell lymphomas among individuals with chronic… More >

George Anderson^*

BIOCELL, Vol.50, No.2, 2026, DOI:10.32604/biocell.2025.073221 - 14 February 2026

Abstract As natural killer (NK) cells eliminate cancer cells and virus-infected cells, as well as modulate various other medical conditions, including aging-associated conditions such as neurodegenerative disorders, understanding NK cell regulation is of considerable clinical importance. This article reviews the role of circadian processes (melatonin and the cortisol system), aryl hydrocarbon receptor, and vagal nerve in the modulation of NK cell function, highlighting the importance of the endogenous mitochondrial melatonergic pathway in NK cells. As circadian and exogenous melatonin increase NK cell cytotoxicity, the presence of the endogenous melatonergic pathway may be of some importance not… More >

Muhammad Farman^1,2,3,*, Muhammad Hashir Zubair⁴, Hua Li⁴, Kottakkaran Sooppy Nisar^5,6, Mohamad Hafez^7,8

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074160 - 29 January 2026

Abstract Lassa Fever (LF) is a viral hemorrhagic illness transmitted via rodents and is endemic in West Africa, causing thousands of deaths annually. This study develops a dynamic model of Lassa virus transmission, capturing the progression of the disease through susceptible, exposed, infected, and recovered populations. The focus is on simulating this model using the fractional Caputo derivative, allowing both qualitative and quantitative analyses of boundedness, positivity, and solution uniqueness. Fixed-point theory and Lipschitz conditions are employed to confirm the existence and uniqueness of solutions, while Lyapunov functions establish the global stability of both disease-free and… More >

Marta Pawłowska^1,*, Dorian Jarek², Jan Milanowski², Karolina Szewczyk-Golec¹

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071891 - 19 January 2026

Abstract Parasitic infections are increasingly recognized as contributors to cancer development, yet the underlying oncogenic mechanisms remain insufficiently understood. Growing evidence from molecular oncology, immunology, and microbiome research suggests that chronic parasitic infections may drive tumorigenesis through sustained inflammation, deregulated signaling pathways, genomic instability, and the release of parasite-derived exosomes that reshape the tumor microenvironment. These insights underscore the need to integrate parasitology with cancer biology to understand infection-associated malignancies better. The aim of this narrative review is to synthesize current knowledge on how selected parasites contribute to cancer development and to highlight emerging therapeutic and… More > Graphic Abstract

Elçin Alaçam^1,*, Mualla Yılmaz²

International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1989-2005, 2025, DOI:10.32604/ijmhp.2025.071033 - 31 December 2025

Abstract Background: Post-cesarean surgical site infection is a frequent complication with significant consequences for maternal, physical, and psychological well-being. This study explored women’s lived experiences of post-cesarean surgical site infection, focusing on emotional responses, treatment experiences, and perceived psychosocial impact. Methods: A qualitative study was conducted using thematic analysis of semi-structured interviews with 23 patients hospitalized due to post-cesarean surgical site infection, selected through purposeful sampling between 15 August 2022, and 15 January 2024. Results: The mean age of the participants in the study was 28.69 ± 5.07 years. Of them, 13 were high school graduates, and 22… More >