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  • Open Access

    ARTICLE

    Numerical Procedure for Fractional HBV Infection with Impact of Antibody Immune

    Sakda Noinang1, Zulqurnain Sabir2, Muhammad Asif Zahoor Raja3, Soheil Salahshour4, Wajaree Weera5,*, Thongchai Botmart5

    CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 2575-2588, 2023, DOI:10.32604/cmc.2023.029046

    Abstract The current investigations are presented to solve the fractional order HBV differential infection system (FO-HBV-DIS) with the response of antibody immune using the optimization based stochastic schemes of the Levenberg-Marquardt backpropagation (LMB) neural networks (NNs), i.e., LMBNNs. The FO-HBV-DIS with the response of antibody immune is categorized into five dynamics, healthy hepatocytes (H), capsids (D), infected hepatocytes (I), free virus (V) and antibodies (W). The investigations for three different FO variants have been tested numerically to solve the nonlinear FO-HBV-DIS. The data magnitudes are implemented 75% for training, 10% for certification and 15% for testing to solve the FO-HBV-DIS with… More >

  • Open Access

    ARTICLE

    Transcriptome Analysis of a Wild Eggplant Germplasm M239 in Response to Verticillium dahliae Infection

    Liyan Wu1, Jie Cheng1,2, Yaju Gong1, Rui Bao1, Zhibin Li1, Min Gui1,*, Guanghui Du2,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 591-609, 2023, DOI:10.32604/phyton.2022.023481

    Abstract In this study, wild eggplant germplasm No. M239, which is highly susceptible to Verticillium wilt, was used as the experimental material. The physiological and biochemical indices (SOD, PAL, MDA and soluble protein) of M239 roots were measured at different times (0, 12, 24, 36, 48, 60 and 72 h) post inoculation with Verticillium dahliae, and the key time points for the M239 response to Verticillium wilt infection were screened. Then, RNA-Seq technology was used to screen the differentially expressed genes (DEGs) in M239 roots at 0, 12 and 48 h post-inoculation (hpi). The transcriptional results of M239 were also compared… More >

  • Open Access

    REVIEW

    The Presence of Human Papillomavirus and Epstein-Barr Virus Infection in Gastric Cancer: A Systematic Study

    Abolfazl Jafari-Sales1, Afsoon Shariat1,*, Hossein Bannazadeh Baghi2, Behzad Baradaran3, Behboud Jafari4

    Oncologie, Vol.24, No.3, pp. 413-426, 2022, DOI:10.32604/oncologie.2022.024161

    Abstract Background and Aim: Gastric cancer (GC) is one of the most common infection-related malignancies worldwide. Human Papillomavirus (HPV) and Epstein-Barr virus (EBV) are among the most important viruses affecting many people worldwide. The potential role of these viruses in gastric tissue may explain the possibility of GC, as seen in Helicobacter pylori (H. pylori). This study aimed to systematically investigate the presence of HPV and EBV in GC. Methods: According to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, this study is a systematic review based on reported cases. The keywords HPV, EBV and GC, were searched… More >

  • Open Access

    ARTICLE

    Characterization and Pathogenicity of Pseudopestalotiopsis vietnamensis Causing Gray Blight of Wuyi Rock Tea (Camellia sinensis) in China and Specific Mechanisms of Disease Infection

    Guangheng Wu1,#,*, Lu Rui2,3,#, Xiang Lu4, Libo Han2, Gan Lv1, Xianyu Fu5, Jinxian Liu5, Nong Zhou3, Chuanhai Zhang1

    Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 131-147, 2023, DOI:10.32604/phyton.2022.021919

    Abstract Gray blight disease (GBD) causes significant losses in tea production in China. Although genes and biological processes involved in resistance to fungal disease in tea plants have been identified, specific mechanisms of the GBD infection process remain unknown. In this study, morphological and multi-gene (TEF-TUB-ITS) phylogenetic characteristics were used to identify isolate CLBB1 of Pseudopestalotiopsis vietnamensis. Pathogenicity tests confirmed that isolate CLBB1 from tea leaves caused GBD in the susceptible tea cultivar Wuyi Rock (Camellia sinensis var. sinensis cv. Shuixian). Spores began to germinate 24 h after infection (hai), and after 48 h, elongated fungal hyphae formed from a single conidium. Transcriptome… More >

  • Open Access

    VIEWPOINT

    Long term immunological perturbations post DAA therapy in chronic HCV/HIV co-infected patients

    SONIA MORETTI, FLAVIA MANCINI, ALESSANDRA BORSETTI*

    BIOCELL, Vol.46, No.12, pp. 2695-2699, 2022, DOI:10.32604/biocell.2022.022257

    Abstract Direct-acting antiviral (DAA) therapies are efficacious for the achievement of sustained virologic response (SVR) in almost all treated hepatitis C virus (HCV)-infected patients. However, the impacts of HCV eradication on immune function and chronic immune activation in the long-term remain controversial and limited, especially in patients co-infected with human immunodeficiency virus (HIV). Indeed, although restoration of many immune responses clearly can be observed, several features of immune perturbations persist over time after HCV clearance. Understanding the degree and reasons of the partial recovery of the immune system in chronic HCV/HIV co-infection after HCV elimination is pivotal to avoid disease progression… More >

  • Open Access

    VIEWPOINT

    Impact of SARS-CoV-2 infection during pregnancy on postnatal brain development: The potential role of glial cells

    LARISSA DANIELE BOBERMIN1,*, LARA SCOPEL MEDEIROS2, FERNANDA WEBER2, GIANCARLO TOMAZZONI DE OLIVEIRA2, LUCÉLIA SANTI3,4,5, WALTER ORLANDO BEYS-DA-SILVA3,4,5, CARLOS-ALBERTO GONÇALVES1,2,6, ANDRÉ QUINCOZES-SANTOS1,2,6

    BIOCELL, Vol.46, No.12, pp. 2517-2523, 2022, DOI:10.32604/biocell.2022.021566

    Abstract Glial cells are crucial for maintaining central nervous system (CNS) homeostasis. They actively participate in immune responses, as well as form functional barriers, such as blood-brain barrier (BBB), which restrict the entry of pathogens and inflammatory mediators into the CNS. In general, viral infections during the gestational period can alter the embryonic and fetal environment, and the related inflammatory response may affect neurodevelopment and lead to behavioral dysfunction during later stage of life, as highlighted by our group for Zika virus infection. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces a cytokine storm and, during pregnancy, may be related to a… More >

  • Open Access

    ARTICLE

    Real-Time Multi-Class Infection Classification for Respiratory Diseases

    Ahmed ElShafee1, Walid El-Shafai2, Abdulaziz Alarifi3,*, Mohammed Amoon3, Aman Singh4, Moustafa H. Aly5

    CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 4157-4177, 2022, DOI:10.32604/cmc.2022.028847

    Abstract Real-time disease prediction has emerged as the main focus of study in the field of computerized medicine. Intelligent disease identification framework can assist medical practitioners in diagnosing disease in a way that is reliable, consistent, and timely, successfully lowering mortality rates, particularly during endemics and pandemics. To prevent this pandemic’s rapid and widespread, it is vital to quickly identify, confine, and treat affected individuals. The need for auxiliary computer-aided diagnostic (CAD) systems has grown. Numerous recent studies have indicated that radiological pictures contained critical information regarding the COVID-19 virus. Utilizing advanced convolutional neural network (CNN) architectures in conjunction with radiological… More >

  • Open Access

    ARTICLE

    Rice Bacterial Infection Detection Using Ensemble Technique on Unmanned Aerial Vehicles Images

    Sathit Prasomphan*

    Computer Systems Science and Engineering, Vol.44, No.2, pp. 991-1007, 2023, DOI:10.32604/csse.2023.025452

    Abstract Establishing a system for measuring plant health and bacterial infection is critical in agriculture. Previously, the farmers themselves, who observed them with their eyes and relied on their experience in analysis, which could have been incorrect. Plant inspection can determine which plants reflect the quantity of green light and near-infrared using infrared light, both visible and eye using a drone. The goal of this study was to create algorithms for assessing bacterial infections in rice using images from unmanned aerial vehicles (UAVs) with an ensemble classification technique. Convolution neural networks in unmanned aerial vehicles image were used. To convey this… More >

  • Open Access

    ARTICLE

    Identification of a new Hazelnut disease in Liaoning Province: Hazelnut husk brown rot

    JUN SUN1,*, MING XIE1, JIACHEN HAO1, NAN MAO1, LIJING CHEN2,*, YUANYUAN QIN3

    BIOCELL, Vol.46, No.9, pp. 2145-2149, 2022, DOI:10.32604/biocell.2022.020500

    Abstract Hazelnut husk brown rot has been identified as a new disease in Liaoning Province in recent years. The objective of this study as to identify the pathogen. [Method] In this study, a standard sample of hazelnut husk brown rot was collected from Songmudao Base in Dalian City, Liaoning Province. The pathogen was identified by the studies of the morphology, pathogenicity, and analyses of ITS and LSU sequences. The pathogen was isolated and purified, which was confirmed by Koch’s postulates. The symptoms after inoculation were the same as those collected directly from a diseased tree, which showed that it was the… More >

  • Open Access

    VIEWPOINT

    SARS-CoV-2 induced myocarditis: Current knowledge about its molecular and pathophysiological mechanisms

    DOMENICO MARIA CARRETTA1,§, MARINA DI DOMENICO2,§, ROBERTO LOVERO3, ROBERTO ARRIGONI4, ANGELIKA ELZBIETA WEGIERSKA5, MARIAROSARIA BOCCELLINO2,*, ANDREA BALLINI2,6,*, IOANNIS ALEXANDROS CHARITOS7,#, LUIGI SANTACROCE5,#

    BIOCELL, Vol.46, No.8, pp. 1779-1788, 2022, DOI:10.32604/biocell.2022.020009

    Abstract The existence of an inflammatory process in the heart muscle, related to a progressive worsening of myocardial function, different etiopathogenetic mechanisms concur and often overlap, thus making the diagnosis and the therapeutic approach complex. As the COVID-19 pandemic progresses, the effects of the disease on the organ systems and in particular on the cardiovascular system are becoming more and more profound. Cardiac involvement is a well-known event with a high percentage of findings in the heart’s magnetic field, even in asymptomatic areas. There are numerous uncertainties regarding their evolution, in the long and short term, due not only to a… More >

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