Md Salah Uddin^*

Journal of Polymer Materials, Vol.42, No.4, pp. 1051-1073, 2025, DOI:10.32604/jpm.2025.070688 - 26 December 2025

Abstract Carbon fiber-reinforced composites (CFRCs) have a wide range of applications in the aerospace, automotive, and energy sectors. A higher specific strength-to-weight ratio is desired in high-performance applications. The failure mechanism of CFRCs involves multiscale phenomena, such as failure that can occur at the matrix, fibers, interface, layers, lamina, and laminates. When an impactor hits the CFRCs, the design involves analyzing each of these stages to prevent failure and optimize the properties of CFRCs under various loading conditions. A numerical model was employed to predict the fracture toughness of CFRCs with varying weight fractions and orientations.… More >

Cheng Song^1,*, Iftikhar Hussein Shah², Ghulam Abbas Ashraf³, Muhammad Arif⁴, Muhammad Aamir Manzoor^1,5,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3427-3451, 2025, DOI:10.32604/phyton.2025.070778 - 01 December 2025

Abstract Heavy metal pollution has become a pervasive environmental issue affecting numerous regions worldwide. Recently, there has been significant attention given to the application of nano-enabled technologies with the purpose of enhancing plant development and alleviating heavy metal stress. This study aimed to illustrate the potential of zinc oxide nanoparticles (ZnO-NPs) to enhance the morphological traits of D. huoshenense exposed to cadmium (Cd) stress. The chemical structure and elemental composition of the ZnO-NPs were characterised by a series of analytical methods, including X-ray diffraction, UV-Vis spectrometry, XPS, and TEM. Plant samples used were collected at 0, 5,… More > Graphic Abstract

Fangyuan Li^1,2,#, Xiaoyuan Hu^1,#, Xiaoge Gao³, Ling Liu³, Tao Li¹, Dan He¹, Jiaxing Cheng¹, Xiaobiao Ma¹, Li Li^1,*, Chunlei Ge^1,*, Hong Yao^1,*

Oncology Research, Vol.33, No.12, pp. 4029-4048, 2025, DOI:10.32604/or.2025.067628 - 27 November 2025

Abstract Background: Liver cancer stem cells (LCSCs) are recognized as pivotal drivers of hepatocellular carcinoma (HCC) progression; however, the molecular mechanisms maintaining their stem-like phenotype remain largely unresolved. This work investigates the role of prefoldin subunit 6-like protein (PFDN6L) in shaping LCSC traits and promoting or restraining HCC progression. Methods: PFDN6L, a cytoskeleton-associated chaperone, was studied using multiple in vitro assays—cell growth evaluation, cell cycle profiling, and spheroid culture—alongside analyses of stemness-associated markers (SOX2, CD133, CD44). Tumorigenic capacity was assessed in xenograft mouse models, and signaling pathway interrogation was performed to define underlying mechanisms. Results: In patient samples, More >

Luyao Sun^#, Ronghao Zhang^#, Kexin Su, Mengjie Wang, Kai Wang, Xiaoyu Wang^*

BIOCELL, Vol.49, No.11, pp. 2217-2237, 2025, DOI:10.32604/biocell.2025.068450 - 24 November 2025

Abstract Objectives: An allergy is an exaggerated immune response, and mast cells play central roles in allergic pathologies. Allyl isothiocyanate can suppress inflammatory responses; however, whether allyl isothiocyanate has a suppressive effect on allergic pathologies remains unclear. Methods: 2,4-dinitrofluorobenzen or ovalbumin was used to establish a mouse model of allergic contact dermatitis or food allergy, respectively. The mRNA level of cytokines was determined using real-time polymerase chain reaction. To examine the effects of allyl isothiocyanate on mast cells, degranulation and intracellular calcium measurement, RNA sequencing, real-time polymerase chain reaction, and Western blotting were performed. Results: Allyl isothiocyanate… More >

Chuansheng Yang¹, Xiaoling Zhou^2,3, Ling Luo³, Zirun Luo⁴, Kaiming Fan^5,*, Chenglai Xia^2,3,*

Oncology Research, Vol.33, No.10, pp. 3065-3076, 2025, DOI:10.32604/or.2025.066058 - 26 September 2025

Abstract Objectives: Novel drug delivery systems have been designed to enhance local drug concentrations while reducing side effects conducive to improved breast cancer treatment outcomes. This study aimed to identify the anti-cancer function of zeolite imidazole ester-based material loaded with camptothecin nanoparticles. Methods: We utilized a zeolitic imidazolate backbone material to fabricate 9-hydroxycamptothecin nanoparticles and investigated their impact on breast cancer cell proliferation. Scanning electron microscopy and Fourier-transform infrared spectroscopy revealed changes in the carrier skeleton of the loaded 9-hydroxyl camptothecin, characterized by a reduction in surface smoothness, accompanied by slight collapses and folds on the… More >

Tatiana M. Astakhova, Nikita S. Karpov, Nataliya O. Dashenkova, Elena V. Alpeeva, Mikhail V. Nesterchuk, Sergey B. Akopov, Arsen S. Mikaelyan, Anfisa S. Ryabchenko, Pavel A. Erokhov, Natalia P. Sharova^*

Oncology Research, Vol.33, No.9, pp. 2573-2595, 2025, DOI:10.32604/or.2025.066611 - 28 August 2025

Abstract Objectives: Proteasomes, multi-subunit proteases, are key actors of cellular protein catabolism and a number of regulatory processes. The detection of subtle proteasome functioning in tumors may contribute to our understanding of the mechanisms of cancer development. The current study aimed to identify the role of low molecular mass protein 2 (LMP2), a proteasome immune subunit, in the development of mouse colon 26 (C26) adenocarcinoma. Methods: The functions of the LMP2 subunit in tumor development in Balb/c mice were studied using its irreversible inhibitor KZR-504. LMP2 activity was detected by the hydrolysis of the fluorogenic substrate… More >

Huifang Yang^1,*, Peixuan Kuang²

Journal of Psychology in Africa, Vol.35, No.4, pp. 535-540, 2025, DOI:10.32604/jpa.2025.070124 - 17 August 2025

Abstract The study investigated the effects of monetary rewards and punishments on the behavioral inhibition in children with attention deficit hyperactivity disorder (ADHD) tendencies. The present study adopted the signal stopping task paradigm, with 66 children with ADHD tendencies as the research subjects. A mixed design of 2 (reward and punishment type: reward, punishment) × 2 (stimulus type: monetary stimulus, social stimulus) was used. The analysis applied a between intervention group (with reward and punishment type variables) and within type of reward approach (by stimulus type as intra subject variables). The results showed that monetary punishment More >

Oncology Research Editorial Offfce

Oncology Research, Vol.33, No.8, pp. 2179-2179, 2025, DOI:10.32604/or.2025.070134 - 18 July 2025

Abstract This article has no abstract. More >

Guo-Zhi Xu^1,2, Han-Yang Guan¹, Yan-Guan Guo¹, Yi-Ran Zhang¹, Jing-Hua Pan¹, Simin Luo³, Hui Ding¹, Yunlong Pan^1,*, Qi Yao^4,*

Oncology Research, Vol.33, No.8, pp. 1947-1967, 2025, DOI:10.32604/or.2025.060440 - 18 July 2025

Abstract Background: Tumor angiogenesis is related to solid tumor occurrence. Ubiquitin-specific peptidase 13 (USP13) is a deubiquitinating enzyme with a pivotal effect on tumor proliferation, metastasis, and tumorigenesis. Nonetheless, its effect on colorectal cancer (CRC) angiogenesis remains poorly understood. Methods: Human umbilical vein endothelial cells (HUVECs) and CRC cells were cultivated, followed by USP13 knockdown/overexpression using shRNA lentiviral vectors or plasmids. Conditioned media (CM) from treated CRC cells were collected to assess HUVEC migration, invasion, and tube formation. Phosphatase and tensin homolog (PTEN) overexpression and recombinant vascular endothelial growth factor A (VEGFA) rescue experiments were performed.… More >

Oncology Research Editorial Office

Oncology Research, Vol.33, No.7, pp. 1801-1802, 2025, DOI:10.32604/or.2025.068988 - 26 June 2025

Abstract This article has no abstract. More >