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  • Open Access

    ARTICLE

    Development of a Comprehensive Ground Suitability Index for Building Construction: A Case Study

    Jerome Gacu1,2,3,*, John Angelo Venus1, Cleo Faith Forio1, Leo Banay1, Eljay Soledad1, Anabeth Famini1, April Rose Fajiculay1, Aprille Ann Sim1, Jason Rufon1

    Revue Internationale de Géomatique, Vol.34, pp. 235-257, 2025, DOI:10.32604/rig.2025.063512 - 25 April 2025

    Abstract The rapid urbanization of rural areas often leads to the construction of medium to high-rise buildings without adequate knowledge of ground suitability, posing significant risks to structural safety and long-term development. This study addresses this critical issue by developing a Comprehensive Ground Suitability Index (CGSI) framework tailored for rural municipalities. Using Geographic Information Systems (GIS) and the Analytic Hierarchy Process (AHP), the CGSI integrates geophysical, geo-environmental, and geohazard parameters to systematically evaluate land suitability for construction. Data were collected from government agencies, previous studies, and field surveys focusing on the Municipality of Odiongan, Romblon. Parameters… More >

  • Open Access

    ARTICLE

    Environmental and Economic Optimization of Multi-Source Power Real-Time Dispatch Based on DGADE-HDJ

    Bin Jiang1, Houbin Wang2,*

    Energy Engineering, Vol.122, No.5, pp. 2001-2057, 2025, DOI:10.32604/ee.2025.062765 - 25 April 2025

    Abstract Considering the special features of dynamic environment economic dispatch of power systems with high dimensionality, strong coupling, nonlinearity, and non-convexity, a GA-DE multi-objective optimization algorithm based on dual-population pseudo-parallel genetic algorithm-differential evolution is proposed in this paper. The algorithm is based on external elite archive and Pareto dominance, and it adopts the cooperative co-evolution mechanism of differential evolution and genetic algorithm. Average entropy and cubic chaotic mapping initialization strategies are proposed to increase population diversity. In the proposed method, we analyze the distribution of neighboring solutions and apply a new Pareto solution set pruning approach.… More >

  • Open Access

    ARTICLE

    Thermal Behavior of a LFP Battery for Residential Applications: Development of a Multi-Physical Numerical Model

    Michela Costa1,*, Adolfo Palombo2, Andrea Ricci2, Ugo Sorge3

    Energy Engineering, Vol.122, No.5, pp. 1629-1643, 2025, DOI:10.32604/ee.2025.062613 - 25 April 2025

    Abstract Effective thermal management is paramount for successfully deploying lithium-ion batteries in residential settings as storage systems for the exploitation of renewable sources. Uncontrolled temperature increases within battery packs can lead to critical issues such as cell overheating, potentially culminating in thermal runaway events and, in extreme cases, leading to fire or explosions. This work presents a comprehensive numerical thermal model of a battery pack made of prototype pouch cells based on lithium ferrophosphate (LFP) chemistry. The multi-physical model is specifically developed to investigate real-world operating scenarios and to assess safety considerations. The considered energy storage… More >

  • Open Access

    ARTICLE

    Design and Development of a Small-Scale Green Hydrogen Vehicle: Hydrogen Consumption Analysis under Varying Loads for Zero-Emission Transport

    Perry Yang Tchie Hunn1, Hadi Nabipour Afrouzi2,*

    Energy Engineering, Vol.122, No.5, pp. 1789-1804, 2025, DOI:10.32604/ee.2025.060124 - 25 April 2025

    Abstract With growing interest in its potential applications across both stationary and transportation sectors, hydrogen has emerged as a promising alternative for environmentally responsible power generation. By replacing traditional fuels, hydrogen can significantly reduce greenhouse gas emissions in the transportation sector. This study focuses on the design and downsizing of a green hydrogen fuel cell car, aiming to scale the concept for larger vehicles. Key components, including fuel cells, electrolysers, and solar panels, were evaluated through extensive laboratory testing. The findings reveal that variations in sunlight impact the solar panel’s hydrogen production rate, with differences of… More > Graphic Abstract

    Design and Development of a Small-Scale Green Hydrogen Vehicle: Hydrogen Consumption Analysis under Varying Loads for Zero-Emission Transport

  • Open Access

    REVIEW

    Promising roles of vitamin D receptor and APRO family proteins for the development of cancer stem cells targeted malignant tumor therapy

    MOEKA NAKASHIMA, NAOKO SUGA, AKARI FUKUMOTO, SAYURI YOSHIKAWA, SATORU MATSUDA*

    Oncology Research, Vol.33, No.5, pp. 1007-1017, 2025, DOI:10.32604/or.2025.059657 - 18 April 2025

    Abstract Malignant tumors are heterogeneous diseases characterized by uncontrolled cell proliferation, invasion, metastasis, and/or recurrence of their malignancies. In particular, cancer stem cells (CSCs) within these tumors might be responsible for the property of invasiveness and/or therapies-resistance. CSCs are a self-renewing, awfully tumorigenic subpopulation of cancer cells, which are notorious for strong chemoresistance and are frequently responsible the aggravated invasion, metastasis, and/or recurrence. Developing targeting therapies against CSCs, therefore, may be deliberated a more encouraging mission for the greater cancer therapy. Innovation for a more potent anti-CSC treatment has been required as soon as possible.… More > Graphic Abstract

    Promising roles of vitamin D receptor and APRO family proteins for the development of cancer stem cells targeted malignant tumor therapy

  • Open Access

    REVIEW

    A review on pathobiology of circulating tumour plasma cells: The sine qua non of poor prognosis in plasma cell neoplasms

    PRATIBHA SUKU1, AISHWARYA DASH1, ARAVIND RADHAKRISHNAN1, PANKAJ MALHOTRA2, MAN UPDESH SINGH SACHDEVA1,*

    Oncology Research, Vol.33, No.5, pp. 1055-1068, 2025, DOI:10.32604/or.2024.055154 - 18 April 2025

    Abstract Circulating plasma cells (CPCs) in patients of plasma cell neoplasm have been an area of intense research in recent decades. Circulating tumor plasma cells (CTPCs) might represent a sub-clone of tumor cells that have exited into peripheral blood as a result of the dynamic interactions between the bone marrow (BM) microenvironment and neoplastic plasma cells. Chemokine receptors like chemokine receptor 4 (CXCR4) and integrins are known to play a role in homing and migration of plasma cells (PCs). The hypoxic microenvironment in the BM niche also contributes to their circulation through various mechanisms. In addition,… More >

  • Open Access

    REVIEW

    Immunomodulatory behavior of CircRNAs in tumor microenvironment

    HAISU LIANG1,2,#, WEI YAN3,#, ZHI LIU1,4, YUNBO HE1,2,5, JIAO HU1, ZHIWEI SHU1, HUIHUANG LI1, BELAYDI OTHMANE1, WENBIAO REN1,6, CHAO QUAN1, DONGXU QIU1, MINFENG CHEN1, WEI XIONG5, BINGNAN ZHANG1,*, PEIHUA LIU1,2,*

    Oncology Research, Vol.33, No.5, pp. 1105-1119, 2025, DOI:10.32604/or.2024.054623 - 18 April 2025

    Abstract Circular RNAs (circRNAs) are a type of non coding RNA that possess unique single stranded circular structures formed through reverse splicing mechanisms. Due to the lack of a free end that is typically susceptible to degradation by nucleases, circular RNAs exhibit resistance to ribonuclease R, making them highly stable in eukaryotic cells. The complex relationship between circRNA dysregulation and various pathophysiological conditions, especially cancer. Tumor microenvironment (TME) is a collective term for various components surrounding tumors and is an important factor affecting tumor development. Simultaneous infiltration of TME by different types of immune cells; These… More >

  • Open Access

    REVIEW

    Research progress on cancer-associated fibroblasts in osteosarcoma

    LIWEN FENG1,2,#,*, YUTING CHEN3,#, WENYI JIN4

    Oncology Research, Vol.33, No.5, pp. 1091-1103, 2025, DOI:10.32604/or.2024.054207 - 18 April 2025

    Abstract Osteosarcoma (OS) is a prevalent primary bone malignancy with limited treatment options. Therefore, it is imperative to investigate and understand the mechanisms underlying OS pathogenesis. Cancer-associated fibroblasts (CAFs) are markedly abundant in tumor stromal cells and are essentially involved in the modulation of tumor occurrence and development. In recent years, CAFs have become a hotspot as researchers aim to elucidate CAF mechanisms that regulate tumor progression. However, most studies on CAFs are limited to a few common cancers, and their association with OS remains elusive. This review describes the role and current knowledge of CAFs More >

  • Open Access

    ARTICLE

    Application of Multi-Criteria Decision and Simulation Approaches to Selection of Additive Manufacturing Technology for Aerospace Application

    Ilesanmi Afolabi Daniyan1,*, Rumbidzai Muvunzi2, Festus Fameso3, Julius Ndambuki3, Williams Kupolati3, Jacques Snyman3

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 1623-1648, 2025, DOI:10.32604/cmc.2025.062092 - 16 April 2025

    Abstract This study evaluates the Fuzzy Analytical Hierarchy Process (FAHP) as a multi-criteria decision (MCD) support tool for selecting appropriate additive manufacturing (AM) techniques that align with cleaner production and environmental sustainability. The FAHP model was validated using an example of the production of aircraft components (specifically fuselage) employing AM technologies such as Wire Arc Additive Manufacturing (WAAM), laser powder bed fusion (L-PBF), Binder Jetting (BJ), Selective Laser Sintering (SLS), and Laser Metal Deposition (LMD). The selection criteria prioritized eco-friendly manufacturing considerations, including the quality and properties of the final product (e.g., surface finish, high strength,… More >

  • Open Access

    ARTICLE

    An Improved Lightweight Safety Helmet Detection Algorithm for YOLOv8

    Lieping Zhang1,2, Hao Ma1, Jiancheng Huang3, Cui Zhang4,*, Xiaolin Gao2

    CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2245-2265, 2025, DOI:10.32604/cmc.2025.061519 - 16 April 2025

    Abstract Detecting individuals wearing safety helmets in complex environments faces several challenges. These factors include limited detection accuracy and frequent missed or false detections. Additionally, existing algorithms often have excessive parameter counts, complex network structures, and high computational demands. These challenges make it difficult to deploy such models efficiently on resource-constrained devices like embedded systems. Aiming at this problem, this research proposes an optimized and lightweight solution called FGP-YOLOv8, an improved version of YOLOv8n. The YOLOv8 backbone network is replaced with the FasterNet model to reduce parameters and computational demands while local convolution layers are added.… More >

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