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  • Open Access

    ARTICLE

    CARD11 serves as a therapeutic biomarker for the drug therapies of ccRCC

    KAIWEN TIAN#, HANZHONG CHEN#, QIANQIAN WANG, FENGLIAN JIANG, CHUNXIANG FENG, TENG LI, XIAOYONG PU, YANLIN TANG*, JIUMIN LIU*

    BIOCELL, Vol.48, No.5, pp. 817-834, 2024, DOI:10.32604/biocell.2024.048737

    Abstract Background: The incidence of clear cell renal cell carcinoma (ccRCC) is globally high; however, despite the introduction of innovative drug therapies, there remains a lack of effective biomarkers for evaluating treatment response. Recently, Caspase recruiting domain-containing protein 11 (CARD11) has garnered attention due to its significant association with tumor development and the immune system. Methods: The expression of CARD11 mRNA and protein in ccRCC were analyzed by public database and immunohistochemistry. The focus of this study is on the epigenomic modifications of CARD11, its expression of ccRCC immunophenotype, and its correlation with response to immunotherapy… More > Graphic Abstract

    CARD11 serves as a therapeutic biomarker for the drug therapies of ccRCC

  • Open Access

    ARTICLE

    Sepsis Prediction Using CNNBDLSTM and Temporal Derivatives Feature Extraction in the IoT Medical Environment

    Sapiah Sakri1, Shakila Basheer1, Zuhaira Muhammad Zain1, Nurul Halimatul Asmak Ismail2,*, Dua’ Abdellatef Nassar1, Manal Abdullah Alohali1, Mais Ayman Alharaki1

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1157-1185, 2024, DOI:10.32604/cmc.2024.048051

    Abstract Background: Sepsis, a potentially fatal inflammatory disease triggered by infection, carries significant health implications worldwide. Timely detection is crucial as sepsis can rapidly escalate if left undetected. Recent advancements in deep learning (DL) offer powerful tools to address this challenge. Aim: Thus, this study proposed a hybrid CNNBDLSTM, a combination of a convolutional neural network (CNN) with a bi-directional long short-term memory (BDLSTM) model to predict sepsis onset. Implementing the proposed model provides a robust framework that capitalizes on the complementary strengths of both architectures, resulting in more accurate and timelier predictions. Method: The sepsis prediction… More >

  • Open Access

    ARTICLE

    Smartphone-Based Wi-Fi Analysis for Bus Passenger Counting

    Mohammed Alatiyyah*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 875-907, 2024, DOI:10.32604/cmc.2024.047790

    Abstract In the contemporary era of technological advancement, smartphones have become an indispensable part of individuals’ daily lives, exerting a pervasive influence. This paper presents an innovative approach to passenger counting on buses through the analysis of Wi-Fi signals emanating from passengers’ mobile devices. The study seeks to scrutinize the reliability of digital Wi-Fi environments in predicting bus occupancy levels, thereby addressing a crucial aspect of public transportation. The proposed system comprises three crucial elements: Signal capture, data filtration, and the calculation and estimation of passenger numbers. The pivotal findings reveal that the system demonstrates commendable… More >

  • Open Access

    ARTICLE

    Multi-cohort comprehensive analysis unveiling the clinical value and therapeutic effect of GNAL in glioma

    ZHEN LIU1,#, LIANGWANG YANG2,#, ZHENGXING XIE1, HUI YU3, TIANYI GU3, DAOMING SHI4, NING CAI1,*, SHENGHUA ZHUO2,*

    Oncology Research, Vol.32, No.5, pp. 965-981, 2024, DOI:10.32604/or.2024.045769

    Abstract Clinical data indicates that glioma patients have poor treatment outcomes and clinical prognosis. The role of olfactory signaling pathway-related genes (OSPRGs) in glioma has not been fully elucidated. In this study, we aimed to investigate the role and relationship between OSPRGs and glioma. Univariate and multivariate Cox regression analyses were performed to assess the relationship between OSPRGs and the overall survival of glioma based on public cohorts, and the target gene (G Protein Subunit Alpha L, GNAL) was screened. The association of GNAL expression with clinicopathological characteristics, gene mutation landscape, tumor immune microenvironment (TIME), deoxyribonucleic acid… More >

  • Open Access

    ARTICLE

    Detection of Student Engagement in E-Learning Environments Using EfficientnetV2-L Together with RNN-Based Models

    Farhad Mortezapour Shiri1,*, Ehsan Ahmadi2, Mohammadreza Rezaee1, Thinagaran Perumal1

    Journal on Artificial Intelligence, Vol.6, pp. 85-103, 2024, DOI:10.32604/jai.2024.048911

    Abstract Automatic detection of student engagement levels from videos, which is a spatio-temporal classification problem is crucial for enhancing the quality of online education. This paper addresses this challenge by proposing four novel hybrid end-to-end deep learning models designed for the automatic detection of student engagement levels in e-learning videos. The evaluation of these models utilizes the DAiSEE dataset, a public repository capturing student affective states in e-learning scenarios. The initial model integrates EfficientNetV2-L with Gated Recurrent Unit (GRU) and attains an accuracy of 61.45%. Subsequently, the second model combines EfficientNetV2-L with bidirectional GRU (Bi-GRU), yielding More >

  • Open Access

    ARTICLE

    Improved Corrosion Resistance of Carbon Reinforced Aluminium Laminates in Atmospheric Environment: Role of Environment Friendly Jute Fibre/ Alumina nano Coating

    M. VASUMATHI1,a,*, VELA MURALI2,b, S. RASHIA BEGUM1,c, N. RAJENDRAN2,d

    Journal of Polymer Materials, Vol.36, No.1, pp. 1-11, 2019, DOI:10.32381/JPM.2019.36.01.1

    Abstract In the Fibre Metal Laminate (FML), Carbon Reinforced Aluminium laminate (CARALL), aluminium is placed next to carbon fibres. The potential difference between the aluminium and carbon is larger, leads to galvanic corrosion, which tries to bring down the durability of the FML. To bring down the effect of corrosion, a material layer is introduced between fibres and aluminium so as to separate them thus lowering the possibility of occurrence of corrosion. Another approach is to coat the surfaces of aluminium with different proportions of aluminium oxide nano particles prior to fabrication of the FML. For More >

  • Open Access

    REVIEW

    A Brief Review of Surface Modification of Carbonyl Iron Powders (CIPs) for Magnetorheological Fluid Applications

    THIRUMALAISAMY SURYAPRABHAA, CHUNGHYUN CHOIA, ZUBAIR AHMED CHANDIOB, LAWRENCE ROBERT MSALILWAB, TAEGWANG YUNC,*, JUN YOUNG CHEONGB,*, BYUNGIL HWANGA,*

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 191-204, 2023, DOI:10.32381/JPM.2023.40.3-4.5

    Abstract Magnetorheological fluids (MRFs) is a smart fluid system that exhibits swift and reversible alterations in their rheological characteristics when exposed to an external magnetic field. MRFs are used for applications in various areas, including automotive systems, robotics, aerospace, and civil engineering. The performance of MRFs depends on the behavior of the dispersed magnetic particles, necessitating thoughtful consideration of particle traits to optimize fluid performance. Carbonyl Iron Powders (CIPs), high purity iron (>98%) reduced from penta carbonyl iron, are widely employed in MRFs due to their exceptional magnetic characteristics. Nevertheless, the innate surfaces of CIPs tend… More >

  • Open Access

    REVIEW

    Types and Sources of Microplastics; The Ubiquitous Environment Contaminant: A Review

    ARCHNA RANI

    Journal of Polymer Materials, Vol.39, No.1-2, pp. 17-35, 2022, DOI:10.32381/JPM.2022.39.1-2.2

    Abstract Accumulation of Microplastics (MPs) in diverse ecosystems is a growing global problem of our time. These are entering into the environment directly (micro-sized plastics manufactured purposefully) and by degradation of plastic products. Due to a diverse range of polymers and additives used to manufacture plastic products, the MPs of different chemical compositions are abundant in the environment. A detailed literature survey revealed that MPs -environment interaction is largely governed by these chemicals and other intrinsic properties of MPs viz. shape, size, density, surface charge, etc. The current investigation primarily aims to review different chemical and More >

  • Open Access

    ARTICLE

    Preparation and Characterization of Self-crosslinked Acrylate Emulsified with Environmentally Friendly Surfactants

    CONGHUI XU, ZHEQING GONG, XIAOLONG CHEN, LIJUN CHEN*

    Journal of Polymer Materials, Vol.40, No.1-2, pp. 47-58, 2023, DOI:10.32381/JPM.2023.40.1-2.4

    Abstract The self-crosslinking polyacrylate latex was prepared via the semi-continuous seed emulsion polymerization technology that methyl methacrylate(MMA) and butyl acrylate (BA)were used as the main monomers and hexafluorobutyl methacrylate (HFMA) and monobutylitaconate (MBI) were used as the modified monomers and glycidyl methacrylate (GMA) was used as the crosslinked monomer which were emulsified with the environmentally friendly mixed surfactant of the isomeric triethylene (9) ether (E-1309) and the lauryl polyoxyethylene ether sulfosuccinate disodium salt (MES-30). The resultant latex and its film is characterized by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC), laser particle sizer, contact More >

  • Open Access

    ARTICLE

    Privacy-Preserving Multi-Keyword Fuzzy Adjacency Search Strategy for Encrypted Graph in Cloud Environment

    Bin Wu1,2, Xianyi Chen3, Jinzhou Huang4,*, Caicai Zhang5, Jing Wang6, Jing Yu1,2, Zhiqiang Zhao7, Zhuolin Mei1,2

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3177-3194, 2024, DOI:10.32604/cmc.2023.047147

    Abstract In a cloud environment, outsourced graph data is widely used in companies, enterprises, medical institutions, and so on. Data owners and users can save costs and improve efficiency by storing large amounts of graph data on cloud servers. Servers on cloud platforms usually have some subjective or objective attacks, which make the outsourced graph data in an insecure state. The issue of privacy data protection has become an important obstacle to data sharing and usage. How to query outsourcing graph data safely and effectively has become the focus of research. Adjacency query is a basic… More >

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