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  • Open Access

    ARTICLE

    Bond-Slip Behavior of Steel Bar and Recycled Steel Fibre-Reinforced Concrete

    Ismail Shah1,2, Jing Li1,3,4,*, Nauman Khan5, Hamad R. Almujibah6, Muhammad Mudassar Rehman2, Ali Raza7, Yun Peng3,4

    Journal of Renewable Materials, Vol.12, No.1, pp. 167-186, 2024, DOI:10.32604/jrm.2023.031503

    Abstract Recycled steel fiber reinforced concrete is an innovative construction material that offers exceptional mechanical properties and durability. It is considered a sustainable material due to its low carbon footprint and environmental friendly characteristics. This study examines the key influencing factors that affect the behavior of this material, such as the steel fiber volume ratio, recycled aggregate replacement rate, concrete strength grade, anchorage length, and stirrup constraint. The study investigates the bond failure morphology, bond-slip, and bond strength constitutive relationship of steel fiber recycled concrete. The results show that the addition of steel fibers at 0.5%,… More >

  • Open Access

    ARTICLE

    Optimization Algorithms of PERT/CPM Network Diagrams in Linear Diophantine Fuzzy Environment

    Mani Parimala1, Karthikeyan Prakash1, Ashraf Al-Quran2,*, Muhammad Riaz3, Saeid Jafari4

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 1095-1118, 2024, DOI:10.32604/cmes.2023.031193

    Abstract The idea of linear Diophantine fuzzy set (LDFS) theory with its control parameters is a strong model for machine learning and optimization under uncertainty. The activity times in the critical path method (CPM) representation procedures approach are initially static, but in the Project Evaluation and Review Technique (PERT) approach, they are probabilistic. This study proposes a novel way of project review and assessment methodology for a project network in a linear Diophantine fuzzy (LDF) environment. The LDF expected task time, LDF variance, LDF critical path, and LDF total expected time for determining the project network… More > Graphic Abstract

    Optimization Algorithms of PERT/CPM Network Diagrams in Linear Diophantine Fuzzy Environment

  • Open Access

    ARTICLE

    NAD+ associated genes as potential biomarkers for predicting the prognosis of gastric cancer

    XIANGDONG SUN1,2,#, HUIJUAN WEN1,2,#, FAZHAN LI1,2, IHTISHAM BUKHARI1,2, FEIFEI REN1,2, XIA XUE1,2, PENGYUAN ZHENG1,2,*, YANG MI1,2,*

    Oncology Research, Vol.32, No.2, pp. 283-296, 2024, DOI:10.32604/or.2023.044618

    Abstract Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism, mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+-regulated genes, including coding and long non-coding genes in cancer development is poorly understood. We constructed a prediction model based on the expression level of NAD+ metabolism-related genes (NMRGs). Furthermore, we validated the expression of NMRGs in gastric cancer (GC) tissues and cell lines; additionally, β-nicotinamide mononucleotide (NMN), a precursor of NAD+, was used to treat the GC cell lines to analyze its effects on the expression level of NMRGs lncRNAs and cellular proliferation, cell… More > Graphic Abstract

    NAD+ associated genes as potential biomarkers for predicting the prognosis of gastric cancer

  • Open Access

    ARTICLE

    TGF-β-regulated different iron metabolism processes in the development and cisplatin resistance of ovarian cancer

    JIANFA WU1,2,#, QIANYI LIAO3,#, LI ZHANG1,2,#, SUQIN WU1,2,*, ZHOU LIU1,2,*

    Oncology Research, Vol.32, No.2, pp. 373-391, 2024, DOI:10.32604/or.2023.031404

    Abstract The impact of different iron metabolism processes (DIMP) on ovarian cancer remains unclear. In this study, we employed various gene chips and databases to investigate the role of DIMP in the initiation and development of ovarian cancer. cBioPortal was used to determine mutations in DIMP-associated genes in ovarian cancer. Kaplan-Meier plotter was used to examine the influence of DIMP on the prognosis of ovarian cancer. By analyzing 1669 serous ovarian cancer cases, we identified a range of mutations in iron metabolism genes, notably in those coding for the transferrin receptor (19%), melanotransferrin (19%), and ceruloplasmin… More >

  • Open Access

    ARTICLE

    Leveraging diverse cell-death patterns to predict the clinical outcome of immune checkpoint therapy in lung adenocarcinoma: Based on muti-omics analysis and vitro assay

    HONGYUAN LIANG1,#, YANQIU LI2,#, YONGGANG QU3, LINGYUN ZHANG4,*

    Oncology Research, Vol.32, No.2, pp. 393-407, 2024, DOI:10.32604/or.2023.031134

    Abstract Advanced LUAD shows limited response to treatment including immune therapy. With the development of sequencing omics, it is urgent to combine high-throughput multi-omics data to identify new immune checkpoint therapeutic response markers. Using GSE72094 (n = 386) and GSE31210 (n = 226) gene expression profile data in the GEO database, we identified genes associated with lung adenocarcinoma (LUAD) death using tools such as “edgeR” and “maftools” and visualized the characteristics of these genes using the “circlize” R package. We constructed a prognostic model based on death-related genes and optimized the model using LASSO-Cox regression methods.… More >

  • Open Access

    ARTICLE

    Zero-DCE++ Inspired Object Detection in Less Illuminated Environment Using Improved YOLOv5

    Ananthakrishnan Balasundaram1,*, Anshuman Mohanty2, Ayesha Shaik1, Krishnadoss Pradeep2, Kedalu Poornachary Vijayakumar2, Muthu Subash Kavitha3

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2751-2769, 2023, DOI:10.32604/cmc.2023.044374

    Abstract Automated object detection has received the most attention over the years. Use cases ranging from autonomous driving applications to military surveillance systems, require robust detection of objects in different illumination conditions. State-of-the-art object detectors tend to fare well in object detection during daytime conditions. However, their performance is severely hampered in night light conditions due to poor illumination. To address this challenge, the manuscript proposes an improved YOLOv5-based object detection framework for effective detection in unevenly illuminated nighttime conditions. Firstly, the preprocessing strategies involve using the Zero-DCE++ approach to enhance lowlight images. It is followed… More >

  • Open Access

    ARTICLE

    Multiple-Object Tracking Using Histogram Stamp Extraction in CCTV Environments

    Ye-Yeon Kang1, Geon Park1, Hyun Yoo2, Kyungyong Chung1,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3619-3635, 2023, DOI:10.32604/cmc.2023.043566

    Abstract Object tracking, an important technology in the field of image processing and computer vision, is used to continuously track a specific object or person in an image. This technology may be effective in identifying the same person within one image, but it has limitations in handling multiple images owing to the difficulty in identifying whether the object appearing in other images is the same. When tracking the same object using two or more images, there must be a way to determine that objects existing in different images are the same object. Therefore, this paper attempts… More >

  • Open Access

    ARTICLE

    Bioinformatic analysis and in vivo validation of angiogenesis related genes in inflammatory bowel disease

    ZEPENG DONG, CHENYE ZHAO, SHIBO HU, KUI YANG, JUNHUI YU*, XUEJUN SUN, JIANBAO ZHENG*

    BIOCELL, Vol.47, No.12, pp. 2735-2745, 2023, DOI:10.32604/biocell.2023.043422

    Abstract Objectives: Angiogenesis plays a significant role in the occurrence and development of inflammatory bowel disease (IBD). The aim of this study is to explore potential angiogenesis related genes (ARGs) in IBD through bioinformatics analysis and in vivo experiments. Methods: GSE57945, GSE87466, and GSE36807 were obtained from the Gene Expression Omnibus database. GSE57945 was used as the training set, while GSE87466 and GSE36807 were used as the validation set. The key ARGs associated with IBD were identified using the least absolute shrinkage and selection operator (LASSO) and random forest methods. These identified ARGs were then utilized to construct… More >

  • Open Access

    ARTICLE

    HEAT TRANSFER BASED NUMERICAL INVESTIGATION OF AIRCRAFT CABIN ENVIRONMENT FROM VARIOUS INLET CONDITIONS

    Zhuohuan Hua,*, Lulu Wanga, Hui Wangb, Mo Yanga

    Frontiers in Heat and Mass Transfer, Vol.6, pp. 1-8, 2015, DOI:10.5098/hmt.6.16

    Abstract A numerical investigation was conducted to study the heat transfer in an aircraft cabin and the effects of air distribution under different angle and inlet velocity conditions. The Reynolds-averaged Navier–Stokes equations and the low Reynolds number turbulence model were used to simulate the airflow in the cabin. Mathematical statistics was used to process the relevant data, and statistical results revealed that different inlet angles and velocities significantly affect air temperature and flow field. The study also determined a set of optimum matching inlet vane angles and inlet velocities that result in an environment which meets More >

  • Open Access

    ARTICLE

    A Bidimensional Finite Element Study of Crack Propagation in Austempered Ductile Iron

    Gustavo von Zeska de França, Roberto Luís de Assumpção, Marco Antonio Luersen*, Carlos Henrique da Silva

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1411-1424, 2023, DOI:10.32604/cmc.2023.043811

    Abstract Austempered ductile iron (ADI) is composed of an ausferritic matrix with graphite nodules and has a wide range of applications because of its high mechanical strength, fatigue resistance, and wear resistance compared to other cast irons. The amount and size of the nodules can be controlled by the chemical composition and austenitizing temperature. As the nodules have lower stiffness than the matrix and can act as stress concentrators, they influence crack propagation. However, the crack propagation mechanism in ADI is not yet fully understood. In this study, we describe a numerical investigation of crack propagation… More >

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