Mani Parimala¹, Karthikeyan Prakash¹, Ashraf Al-Quran^2,*, Muhammad Riaz³, Saeid Jafari⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 1095-1118, 2024, DOI:10.32604/cmes.2023.031193

Abstract The idea of linear Diophantine fuzzy set (LDFS) theory with its control parameters is a strong model for machine learning and optimization under uncertainty. The activity times in the critical path method (CPM) representation procedures approach are initially static, but in the Project Evaluation and Review Technique (PERT) approach, they are probabilistic. This study proposes a novel way of project review and assessment methodology for a project network in a linear Diophantine fuzzy (LDF) environment. The LDF expected task time, LDF variance, LDF critical path, and LDF total expected time for determining the project network are all computed using LDF… More > Graphic Abstract

XIANGDONG SUN^1,2,#, HUIJUAN WEN^1,2,#, FAZHAN LI^1,2, IHTISHAM BUKHARI^1,2, FEIFEI REN^1,2, XIA XUE^1,2, PENGYUAN ZHENG^1,2,*, YANG MI^1,2,*

Oncology Research, Vol.32, No.2, pp. 283-296, 2024, DOI:10.32604/or.2023.044618

Abstract Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism, mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+-regulated genes, including coding and long non-coding genes in cancer development is poorly understood. We constructed a prediction model based on the expression level of NAD+ metabolism-related genes (NMRGs). Furthermore, we validated the expression of NMRGs in gastric cancer (GC) tissues and cell lines; additionally, β-nicotinamide mononucleotide (NMN), a precursor of NAD+, was used to treat the GC cell lines to analyze its effects on the expression level of NMRGs lncRNAs and cellular proliferation, cell cycle, apoptosis, and senescence-associated secretory… More > Graphic Abstract

JIANFA WU^1,2,#, QIANYI LIAO^3,#, LI ZHANG^1,2,#, SUQIN WU^1,2,*, ZHOU LIU^1,2,*

Oncology Research, Vol.32, No.2, pp. 373-391, 2024, DOI:10.32604/or.2023.031404

Abstract The impact of different iron metabolism processes (DIMP) on ovarian cancer remains unclear. In this study, we employed various gene chips and databases to investigate the role of DIMP in the initiation and development of ovarian cancer. cBioPortal was used to determine mutations in DIMP-associated genes in ovarian cancer. Kaplan-Meier plotter was used to examine the influence of DIMP on the prognosis of ovarian cancer. By analyzing 1669 serous ovarian cancer cases, we identified a range of mutations in iron metabolism genes, notably in those coding for the transferrin receptor (19%), melanotransferrin (19%), and ceruloplasmin (10%) in the iron import… More >

HONGYUAN LIANG^1,#, YANQIU LI^2,#, YONGGANG QU³, LINGYUN ZHANG^4,*

Oncology Research, Vol.32, No.2, pp. 393-407, 2024, DOI:10.32604/or.2023.031134

Abstract Advanced LUAD shows limited response to treatment including immune therapy. With the development of sequencing omics, it is urgent to combine high-throughput multi-omics data to identify new immune checkpoint therapeutic response markers. Using GSE72094 (n = 386) and GSE31210 (n = 226) gene expression profile data in the GEO database, we identified genes associated with lung adenocarcinoma (LUAD) death using tools such as “edgeR” and “maftools” and visualized the characteristics of these genes using the “circlize” R package. We constructed a prognostic model based on death-related genes and optimized the model using LASSO-Cox regression methods. By calculating the cell death… More >

Ananthakrishnan Balasundaram^1,*, Anshuman Mohanty², Ayesha Shaik¹, Krishnadoss Pradeep², Kedalu Poornachary Vijayakumar², Muthu Subash Kavitha³

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 2751-2769, 2023, DOI:10.32604/cmc.2023.044374

Abstract Automated object detection has received the most attention over the years. Use cases ranging from autonomous driving applications to military surveillance systems, require robust detection of objects in different illumination conditions. State-of-the-art object detectors tend to fare well in object detection during daytime conditions. However, their performance is severely hampered in night light conditions due to poor illumination. To address this challenge, the manuscript proposes an improved YOLOv5-based object detection framework for effective detection in unevenly illuminated nighttime conditions. Firstly, the preprocessing strategies involve using the Zero-DCE++ approach to enhance lowlight images. It is followed by optimizing the existing YOLOv5… More >

Ye-Yeon Kang¹, Geon Park¹, Hyun Yoo², Kyungyong Chung^1,*

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3619-3635, 2023, DOI:10.32604/cmc.2023.043566

Abstract Object tracking, an important technology in the field of image processing and computer vision, is used to continuously track a specific object or person in an image. This technology may be effective in identifying the same person within one image, but it has limitations in handling multiple images owing to the difficulty in identifying whether the object appearing in other images is the same. When tracking the same object using two or more images, there must be a way to determine that objects existing in different images are the same object. Therefore, this paper attempts to determine the same object… More >

ZEPENG DONG, CHENYE ZHAO, SHIBO HU, KUI YANG, JUNHUI YU^*, XUEJUN SUN, JIANBAO ZHENG^*

BIOCELL, Vol.47, No.12, pp. 2735-2745, 2023, DOI:10.32604/biocell.2023.043422

Abstract Objectives: Angiogenesis plays a significant role in the occurrence and development of inflammatory bowel disease (IBD). The aim of this study is to explore potential angiogenesis related genes (ARGs) in IBD through bioinformatics analysis and in vivo experiments. Methods: GSE57945, GSE87466, and GSE36807 were obtained from the Gene Expression Omnibus database. GSE57945 was used as the training set, while GSE87466 and GSE36807 were used as the validation set. The key ARGs associated with IBD were identified using the least absolute shrinkage and selection operator (LASSO) and random forest methods. These identified ARGs were then utilized to construct a diagnostic model… More >

Zhuohuan Hu^a,*, Lulu Wang^a, Hui Wang^b, Mo Yang^a

Frontiers in Heat and Mass Transfer, Vol.6, pp. 1-8, 2015, DOI:10.5098/hmt.6.16

Abstract A numerical investigation was conducted to study the heat transfer in an aircraft cabin and the effects of air distribution under different angle and inlet velocity conditions. The Reynolds-averaged Navier–Stokes equations and the low Reynolds number turbulence model were used to simulate the airflow in the cabin. Mathematical statistics was used to process the relevant data, and statistical results revealed that different inlet angles and velocities significantly affect air temperature and flow field. The study also determined a set of optimum matching inlet vane angles and inlet velocities that result in an environment which meets standard requirements and is energy… More >

Gustavo von Zeska de França, Roberto Luís de Assumpção, Marco Antonio Luersen^*, Carlos Henrique da Silva

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1411-1424, 2023, DOI:10.32604/cmc.2023.043811

Abstract Austempered ductile iron (ADI) is composed of an ausferritic matrix with graphite nodules and has a wide range of applications because of its high mechanical strength, fatigue resistance, and wear resistance compared to other cast irons. The amount and size of the nodules can be controlled by the chemical composition and austenitizing temperature. As the nodules have lower stiffness than the matrix and can act as stress concentrators, they influence crack propagation. However, the crack propagation mechanism in ADI is not yet fully understood. In this study, we describe a numerical investigation of crack propagation in ADIs subjected to cyclic… More >

Abdul Rehman, Dongsun Kim^*, Anand Paul

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2289-2307, 2023, DOI:10.32604/cmc.2023.036435

Abstract Disasters such as conflagration, toxic smoke, harmful gas or chemical leakage, and many other catastrophes in the industrial environment caused by hazardous distance from the peril are frequent. The calamities are causing massive fiscal and human life casualties. However, Wireless Sensors Network-based adroit monitoring and early warning of these dangerous incidents will hamper fiscal and social fiasco. The authors have proposed an early fire detection system uses machine and/or deep learning algorithms. The article presents an Intelligent Industrial Monitoring System (IIMS) and introduces an Industrial Smart Social Agent (ISSA) in the Industrial SIoT (ISIoT) paradigm. The proffered ISSA empowers smart… More >