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  • Open Access


    Biochemical association between the prevalence of genetic polymorphism and myocardial infarction


    BIOCELL, Vol.47, No.3, pp. 473-484, 2023, DOI:10.32604/biocell.2023.025930

    Abstract Genetic polymorphism has a vital role in the pathogenesis and development of myocardial infarction (MI). Single nucleotide polymorphism at any one of the amino acid sequences can result in a diseased state. A single gene can exhibit genetic polymorphism at more than one position giving rise to different variants. Genetic polymorphism of angiotensinogen (AGT) M235T, AGT T174M, and angiotensin-1-converting enzyme (ACE) I/D, endothelial nitric oxide synthase (eNOS), and methylenetetrahydrofolate reductase (MTHFR) can be a risk factor for MI. However, it is important to study the prevalence of genetic polymorphisms of these genes among different populations. MI is influenced by genetic… More >

  • Open Access


    Review of Computational Techniques for the Analysis of Abnormal Patterns of ECG Signal Provoked by Cardiac Disease

    Revathi Jothiramalingam1, Anitha Jude2, Duraisamy Jude Hemanth2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.128, No.3, pp. 875-906, 2021, DOI: 10.32604/cmes.2021.016485

    Abstract The 12-lead ECG aids in the diagnosis of myocardial infarction and is helpful in the prediction of cardiovascular disease complications. It does, though, have certain drawbacks. For other electrocardiographic anomalies such as Left Bundle Branch Block and Left Ventricular Hypertrophy syndrome, the ECG signal with Myocardial Infarction is difficult to interpret. These diseases cause variations in the ST portion of the ECG signal. It reduces the clarity of ECG signals, making it more difficult to diagnose these diseases. As a result, the specialist is misled into making an erroneous diagnosis by using the incorrect therapeutic technique. Based on these concepts,… More >

  • Open Access


    Effect of Ultrafine Nano-Zinc Particles on Cardiac Structure and Function in Myocardial Infarction Rabbits

    Pei Niu1, Li Li1, Yufan Huang2, Yunlong Huo3,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 45-45, 2019, DOI:10.32604/mcb.2019.05724

    Abstract Due to ultrafine Nano-zinc particles are major component of PM0.1, so we aimed to investigate how ultrafine Nano-zinc particles effect on cardiac structure and function in myocardial infarction (MI) rabbits. We chose twenty-four New Zealand rabbits who were divided into sham group, MI group and MI exposure group randomly, 8 rabbits in each group. We preformed LAD ligation operation in MI group and MI exposure group. After two weeks rabbits suffered from MI successfully, we put the MI exposure group into ventilation chamber filled with 500 ug/m3 ultrafine Nano-zinc particles for 6 hours per day. Sham group and MI group… More >

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