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  • Open Access

    REVIEW

    Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes

    Jaswinder Kaur1, Manish Vyas2, Joginder Singh1, Ram Prasad3,*, Jeena Gupta1,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 795-803, 2020, DOI:10.32604/phyton.2020.09420 - 09 November 2020

    Abstract In recent years, there has been an increase in epidemiological studies to highlight the health benefits of plant secondary metabolites. Flavonoids (polyphenolic plant secondary metabolites) are recently emerging as an important source for the discovery of new drugs increasing their pharmaceuticals, nutraceutical and medicinal applications. Naringenin is a flavanone, enriched in citrus fruits, tomatoes, bergamot, etc. which has been evaluated extensively for managing diabetes. However, in addition to this, naringenin had been ascribed to various important biological activities like antioxidant, antiviral, anticancer, anti-inflammatory, antiestrogenic, etc. This article aims at highlighting the therapeutic value of naringenin More >

  • Open Access

    ARTICLE

    Numerical Study of High-Temperature Nonequilibrium Flow around Reentry Vehicle Coupled with Thermal Radiation

    Jingying Wang, Fangzhou Han*, Li Lei, Chunhian Lee

    FDMP-Fluid Dynamics & Materials Processing, Vol.16, No.3, pp. 601-613, 2020, DOI:10.32604/fdmp.2020.09624 - 25 May 2020

    Abstract Accurate aerodynamic heating prediction is of great significance to current manned space flight and deep space exploration missions. The temperature in the shock layer surrounding the reentry vehicle can reach up to 10,000 K and result in remarkable thermochemical nonequilibrium, as well as considerable radiative heat transfer. In general, high-temperature flow simulations coupled with thermal radiation require appropriate numerical schemes and physical models. In this paper, the equations governing hypersonic nonequilibrium flow, based on a three-temperature model combined with a thermal radiation solving approach, are used to investigate the radiation effects in the reentry shock… More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of Epoxy methacrylate of (2E, 6E)-Bis(4-hydroxybenzylidene)-4- methylcyclohexanone

    JALPA V. CHOPDA, DHARMESH B. SANKHAVARA, JIGNESH P. PATEL, P. H. PARSANIA*

    Journal of Polymer Materials, Vol.36, No.4, pp. 391-399, 2019, DOI:10.32381/JPM.2019.36.04.8

    Abstract The epoxymethcrylate resin (EMBHBCMA) of (2E, 6E)-bis(4-hydroxybenzylidene)-4- methylcyclohexanone(EMBHBC) was synthesized by condensing EMBHBC and methacrylic acid (1:2 mole ratio) by using 1,4-dioxane as a solvent and triethylamine as a catalyst at reflux temperature for 1-5 h to get acid value < 10. The structure of EMBHBCMA was supported by UV-Vis, FTIR, 1 HNMR and 13CNMR spectroscopic techniques. Molecular weights and molecular weight distribution of EMBHBCMA were determined by gel permeation chromatography. EMBHBCMA is thermally stable up to about 300°C and followed two step degradation reactions. Kinetic parameters such as n, Ea, A and ΔS* were determined More >

  • Open Access

    ARTICLE

    Synthesis and Physico-Chemical Analysis of Epoxy Methacrylate of (2E, 6E)-2,6-Bis(4- hydroxybenzylidene)cyclohexanone

    DHARMESH B. SANKHAVARA, JALPA V. CHOPDA, JIGNESH P. PATEL, PARSOTAM H. PARSANIA*

    Journal of Polymer Materials, Vol.36, No.4, pp. 371-379, 2019, DOI:10.32381/JPM.2019.36.04.6

    Abstract The epoxy methacrylate of (2E,6E)-2, 6-bis(4-hydroxybenzylidene)cyclohexanone (EBHBCMA) was synthesized by condensing 0.02 equi. EBHBC, 0.04 equi. methacrylic acid, 50 mL THF as a solvent and 0.2 mL triethylamine as a catalyst at reflux temperature for 1-5 h to get acid value < 10. EBHBCMA showed good solubility in common solvents. The structure of EBHBCMA was supported by UV-Vis., FTIR, 1 H NMR, and 13C NMR spectroscopic techniques. DSC thermogram of EBHBCMA exhibited two endothermic peaks (86.4 and 117.1 °C) and one exothermic peak (142.6°C) due to moisture release, melting and curing of the resin, respectively. More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of Epoxy Resin of (2E, 6E) - Bis (4-hydroxybenzylidene) -4-methylcyclohexanone

    JALPA V. CHOPDA, DHARMESH B. SANKHAVARA, JIGNESH P. PATEL, P. H. PARSANIA*

    Journal of Polymer Materials, Vol.36, No.1, pp. 101-109, 2019, DOI:10.32381/JPM.2019.36.01.8

    Abstract The epoxy resin (EMBHBC) of (2E,6E)-bis (4-hydroxybenzylidene)-4-methyl cyclohexanone (MBHBC) was synthesized by condensing 0.5 mol MBHBC and 2.5 mol epichlorohydrin in 500 mL isopropyl alcohol as a solvent and 1.0 mol NaOH in 50 mL water as a catalyst at 80°C for 3 h. The structure of EMBHBC was supported by UV-Vis, FTIR, 1 HNMR and 13CNMR spectroscopic techniques. Molecular weights and molecular weight distribution of EMBHBC were determined by gel permeation chromatography. DSC thermogram of EMBHC showed one endothermic transition (95.9°C) and two exothermic transitions (317.7°C and 382.2°C) due to melting and decomposition transitions, respectively. More >

  • Open Access

    ARTICLE

    Synthesis and Physico-chemical Studies on Chalcone Based Epoxy Resin of (2E, 6E)-Bis (4-hydroxybenzylidene) cyclohexanone

    DHARMESH B. SANKHAVARA, JALPA CHOPDA, JIGNESH P. PATEL, P. H. PARSANIA*

    Journal of Polymer Materials, Vol.36, No.1, pp. 13-21, 2019, DOI:10.32381/JPM.2019.36.01.2

    Abstract Chalcone based epoxy resin (EBHBC) of (2E, 6E)- bis(4-hydroxybenzylidene) cyclohexanone (BHBC) was synthesized by condensing 0.5 mol BHBC and 2.5 mol epichlorohydrin in 500 mL isopropanol as a solvent and 1.0 mol NaOH in 50 mL water as a catalyst at 80o C. The structure of EBHBC is supported by spectral techniques. Molecular weights and molecular weight distribution of EBHBC were determined by gel permeation chromatography. DSC thermogram of EBHC showed one endothermic transition (146.1°C) and two endothermic transitions (253.52°C and 397.34°C) due to melting, some physical change and decomposition transitions, respectively. EBHBC is thermally More >

  • Open Access

    ARTICLE

    Use of vasoactive agents in postoperative pediatric cardiac patients: Insights from a national database

    Rohit S. Loomba1, Saul Flores2

    Congenital Heart Disease, Vol.14, No.6, pp. 1176-1184, 2019, DOI:10.1111/chd.12837

    Abstract Objective: The main goal of this study is to examine the variation in vasoactive agent prescription patterns across a large cohort of patients. In addition, we sought to determine the association between the number of vasoactive agents used during admissions and characteristics of admissions utilizing varying numbers of vasoactive agents.
    Methods: This was a multi-institutional, cross-sectional study of the pediatric health information system database of patients who underwent congenital heart surgery and received vasoactive agents from 2004 to 2015. The international classification of disease-9 (ICD-9) codes were used to select admissions to those only pertaining to cardiac… More >

  • Open Access

    ARTICLE

    High Capacity Data Hiding in Encrypted Image Based on Compressive Sensing for Nonequivalent Resources

    Di Xiao1,*, Jia Liang1, Qingqing Ma1, Yanping Xiang1, Yushu Zhang2

    CMC-Computers, Materials & Continua, Vol.58, No.1, pp. 1-13, 2019, DOI:10.32604/cmc.2019.02171

    Abstract To fulfill the requirements of data security in environments with nonequivalent resources, a high capacity data hiding scheme in encrypted image based on compressive sensing (CS) is proposed by fully utilizing the adaptability of CS to nonequivalent resources. The original image is divided into two parts: one part is encrypted with traditional stream cipher; the other part is turned to the prediction error and then encrypted based on CS to vacate room simultaneously. The collected non-image data is firstly encrypted with simple stream cipher. For data security management, the encrypted non-image data is then embedded More >

  • Open Access

    ARTICLE

    Tanshinone Suppresses Arecoline-Induced Epithelial–Mesenchymal Transition in Oral Submucous Fibrosis by Epigenetically Reactivating the p53 Pathway

    Lian Zheng, Zhen-Jie Guan, Wen-Ting Pan, Tian-Feng Du, Yu-Jia Zhai, Jia Guo

    Oncology Research, Vol.26, No.3, pp. 483-494, 2018, DOI:10.3727/096504017X14941825760362

    Abstract Oral submucous fibrosis (OSF) induced by chewing of the areca nut has been considered to be a precancerous lesion with a high probability of developing oral squamous cell carcinoma. Tanshinone (TSN) is the main component extracted from Salvia miltiorrhiza, a traditional Chinese medicine, which was found to have diverse pharmacological effects, such as anti-inflammatory and antitumor. In the current study, we aimed to identify the inhibitory effects and the underlying mechanism of TSN on OSF progress. We found that treatment with TSN inhibited the arecoline-mediated proliferation of primary human oral mucosal fibroblasts and reversed the… More >

  • Open Access

    RETRACTION

    Retraction Notice to: Mitigating Content Caching Attack in NDN

    Zhiqiang Ruan1,*, Haibo Luo1, Wenzhong Lin1, Jie Wang2

    CMC-Computers, Materials & Continua, Vol.57, No.3, pp. 653-653, 2018, DOI:10.32604/cmc.2018.00653

    Abstract none More >

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