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  • Open Access

    ARTICLE

    Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK

    PEI QIN#, MIAO LIU#, XIN WANG, JIANHUA MA*

    BIOCELL, Vol.48, No.3, pp. 513-523, 2024, DOI:10.32604/biocell.2023.045640

    Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson’s disease); however, its prolonged use caused dyskinesia (LID). Due to the varied presentation of LID, effective treatment options are scarce. Flavonoids reported their neuroprotective activity by ameliorating acetylcholinesterase, monoamine oxidase, and neuroinflammation. Kaempferol is another flavonoid bearing these potentials. Aim: To evaluate neuroprotective activity of kaempferol in dyskinetic rats. Methods: PD was developed in Sprague-Dawley rats by injecting combination of L-ascorbic acid (10 µL) + 6-OHDA (12 µg) in medial forebrain bundle to induce neuronal damage in substantial nigra (SNr). LID was induced by administrating combination of L-dopa (20 mg/kg)… More > Graphic Abstract

    Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK

  • Open Access

    ARTICLE

    Multi-Time Scale Operation and Simulation Strategy of the Park Based on Model Predictive Control

    Jun Zhao*, Chaoying Yang, Ran Li, Jinge Song

    Energy Engineering, Vol.121, No.3, pp. 747-767, 2024, DOI:10.32604/ee.2023.042806

    Abstract Due to the impact of source-load prediction power errors and uncertainties, the actual operation of the park will have a wide range of fluctuations compared with the expected state, resulting in its inability to achieve the expected economy. This paper constructs an operating simulation model of the park power grid operation considering demand response and proposes a multi-time scale operating simulation method that combines day-ahead optimization and model predictive control (MPC). In the day-ahead stage, an operating simulation plan that comprehensively considers the user’s side comfort and operating costs is proposed with a long-term time scale of 15 min. In… More >

  • Open Access

    ARTICLE

    BLECA: A Blockchain-Based Lightweight and Efficient Cross-Domain Authentication Scheme for Smart Parks

    Fengting Luo, Ruwei Huang*, Yuyue Chen

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1815-1835, 2023, DOI:10.32604/cmc.2023.041676

    Abstract Smart parks serve as integral components of smart cities, where they play a pivotal role in the process of urban modernization. The demand for cross-domain cooperation among smart devices from various parks has witnessed a significant increase. To ensure secure communication, device identities must undergo authentication. The existing cross-domain authentication schemes face issues such as complex authentication paths and high certificate management costs for devices, making it impractical for resource-constrained devices. This paper proposes a blockchain-based lightweight and efficient cross-domain authentication protocol for smart parks, which simplifies the authentication interaction and requires every device to maintain only one certificate. To… More >

  • Open Access

    ARTICLE

    Emergency Energy Management of Microgrid in Industrial Park Based on Robust Optimization

    Haoliang Yang*, Yonggang Dong, Zhifang Yang

    Energy Engineering, Vol.120, No.12, pp. 2917-2931, 2023, DOI:10.32604/ee.2023.029167

    Abstract Reducing the impact of power outages and maintaining the power supply duration must be considered in implementing emergency energy dispatching in micro-networks. This paper studies a new emergency energy treatment method based on the robust optimal method and the industrial park micro-network with the optical energy storage system. After controlling the load input, a control strategy of adjusting and removing is proposed. Rolling optimal theory is applied to emergency energy scheduling based on a robust optimal mathematical model. A weighting factor is introduced into the optimal model to balance the importance of reducing and retaining the power supply. Uncertainty is… More >

  • Open Access

    ARTICLE

    Distribution Network Optimization Model of Industrial Park with Distributed Energy Resources under the Carbon Neutral Targets

    Xiaobao Yu*, Kang Yang

    Energy Engineering, Vol.120, No.12, pp. 2741-2760, 2023, DOI:10.32604/ee.2023.028041

    Abstract Taking an industrial park as an example, this study aims to analyze the characteristics of a distribution network that incorporates distributed energy resources (DERs). The study begins by summarizing the key features of a distribution network with DERs based on recent power usage data. To predict and analyze the load growth of the industrial park, an improved back-propagation algorithm is employed. Furthermore, the study classifies users within the industrial park according to their specific power consumption and supply requirements. This user segmentation allows for the introduction of three constraints: node voltage, wire current, and capacity of DERs. By incorporating these… More >

  • Open Access

    ARTICLE

    Use of Additive Based on Non-Timber Forest Products for the Ecological Stabilization of Raw Earth: Case of the Parkia Biglobosa Nut and Vitellaria Paradoxa

    Bio Chéïssou Koto Tamou1,2,3, Jean-Michel Mechling2, Crespin Prudence Yabi1,*, Gildas Edjrossè F. Godonou3, Edmond Codjo Adjovi1, Mohamed Gibigaye3, André Lecomte2, Nicolas Brosse4

    Journal of Renewable Materials, Vol.11, No.12, pp. 4143-4160, 2023, DOI:10.32604/jrm.2023.030509

    Abstract The housing sector today uses elaborate materials such as cement, iron, sand, often prohibitively expensive and whose production generates a strong environmental impact (scarcity of resources, transport, greenhouse gas greenhouse, etc.). In order to meet the challenges of sustainable development, earth construction is experiencing a resurgence of interest these days. Despite its many advantages, raw earth material has drawbacks, in particular its low mechanical resistance and its loss of geometric characteristics in the face of water, which slow down its development. As part of this study, the mechanical characteristics and durability of raw earth were improved by using residual water… More > Graphic Abstract

    Use of Additive Based on Non-Timber Forest Products for the Ecological Stabilization of Raw Earth: Case of the Parkia Biglobosa Nut and Vitellaria Paradoxa

  • Open Access

    ARTICLE

    Deep Learning Model for Big Data Classification in Apache Spark Environment

    T. M. Nithya1,*, R. Umanesan2, T. Kalavathidevi3, C. Selvarathi4, A. Kavitha5

    Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 2537-2547, 2023, DOI:10.32604/iasc.2022.028804

    Abstract Big data analytics is a popular research topic due to its applicability in various real time applications. The recent advent of machine learning and deep learning models can be applied to analyze big data with better performance. Since big data involves numerous features and necessitates high computational time, feature selection methodologies using metaheuristic optimization algorithms can be adopted to choose optimum set of features and thereby improves the overall classification performance. This study proposes a new sigmoid butterfly optimization method with an optimum gated recurrent unit (SBOA-OGRU) model for big data classification in Apache Spark. The SBOA-OGRU technique involves the… More >

  • Open Access

    ARTICLE

    Analysis of CLARANS Algorithm for Weather Data Based on Spark

    Jiahao Zhang, Honglin Wang*

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 2427-2441, 2023, DOI:10.32604/cmc.2023.038462

    Abstract With the rapid development of technology, processing the explosive growth of meteorological data on traditional standalone computing has become increasingly time-consuming, which cannot meet the demands of scientific research and business. Therefore, this paper proposes the implementation of the parallel Clustering Large Application based upon RANdomized Search (CLARANS) clustering algorithm on the Spark cloud computing platform to cluster China’s climate regions using meteorological data from 1988 to 2018. The aim is to address the challenge of applying clustering algorithms to large datasets. In this paper, the morphological similarity distance is adopted as the similarity measurement standard instead of Euclidean distance,… More >

  • Open Access

    ARTICLE

    Privacy Preserved Brain Disorder Diagnosis Using Federated Learning

    Ali Altalbe1,2,*, Abdul Rehman Javed3

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 2187-2200, 2023, DOI:10.32604/csse.2023.040624

    Abstract Federated learning has recently attracted significant attention as a cutting-edge technology that enables Artificial Intelligence (AI) algorithms to utilize global learning across the data of numerous individuals while safeguarding user data privacy. Recent advanced healthcare technologies have enabled the early diagnosis of various cognitive ailments like Parkinson’s. Adequate user data is frequently used to train machine learning models for healthcare systems to track the health status of patients. The healthcare industry faces two significant challenges: security and privacy issues and the personalization of cloud-trained AI models. This paper proposes a Deep Neural Network (DNN) based approach embedded in a federated… More >

  • Open Access

    ARTICLE

    Research on Parking Path Planing Based on A-Star Algorithm

    Zhiliang Deng, Dong Wang*

    Journal of New Media, Vol.5, No.1, pp. 55-64, 2023, DOI:10.32604/jnm.2023.040252

    Abstract The issue of finding available parking spaces and mitigating congestion during parking is a persistent challenge for numerous car owners in urban areas. In this paper, we propose a novel method based on the A-star algorithm to calculate the optimal parking path to address this issue. We integrate a road impedance function into the conventional A-star algorithm to compute path duration and adopt a fusion function composed of path length and duration as the weight matrix for the A-star algorithm to achieve optimal path planning. Furthermore, we conduct simulations using parking lot modeling to validate the effectiveness of our approach,… More >

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