Onur Doyurgan^1,*, Osman Akdeniz², Fatih Özdemir¹, Yiğit Kılıç¹, Bedri Aldudak³

Congenital Heart Disease, Vol.17, No.3, pp. 313-323, 2022, DOI:10.32604/chd.2022.018479

Abstract Background: Vascular access used for pediatric cardiac catheterization is one of the most important factors that affects the success of the procedure. We aimed to compare the effect, success, and complications of cardiac catheterizations performed by carotid cut-down or femoral puncture in newborns or young infants. Methods: We included who underwent catheterization in our department between 28 January 2017 and 15 April 2021. These patients underwent balloon aortic valvuloplasty, balloon coarctation angioplasty, ductal stenting, diagnostic procedures for aortic arch pathologies, and modified Blalock-Taussig in-shunt intervention. Patients were divided into two groups: femoral puncture (group = 1) and carotid cut-down (CC,… More >

Omnia Shafei^1,2,*, Alyaa A. Kotby^1,2, Mona M. El Ganzoury^1,2, Nevin M. Habeeb^1,2, Eman Elsayed^1,2

Congenital Heart Disease, Vol.17, No.2, pp. 173-185, 2022, DOI:10.32604/CHD.2021.016987

Abstract Objectives: We aimed to evaluate the effect of percutaneous atrial septal defect (ASD) closure in children using right heart indices and serum galectin-3 (Gal-3), as potential biomarkers of right heart remodeling. Methods: This case–control prospective study included 40 children with ASD and 25 control subjects. An echocardiographic evaluation was performed before the procedure, as well as 24 h, 1 month, and 6 months after intervention. Serum Gal-3 was measured before, and 1 month after the procedure. Results: Serum Gal-3 concentration, right atrial (RA) dimensions, right ventricular (RV) dimensions, indexed RA area, and right index of myocardial performance (RIMP) were significantly… More >

Olivia Lenoir^1,2, Daniel Quandt^1,2, Oliver Kretschmar^1,2, Walter Knirsch^1,2,*

Congenital Heart Disease, Vol.17, No.2, pp. 161-172, 2022, DOI:10.32604/chd.2022.016598

Abstract Objectives: Factors influencing results of balloon valvuloplasty (BVP) of pulmonary valve stenosis (PS) in children are investigated. Background: BVP has become the standard of care for PS, medium-term results are not uniform and depend on various preconditions. Methods: We analysed the medium-term results of BVP of PS in children in an observational, single centre study. Need for additional procedure was defined as outcome after initial BVP. Results: We included 143 children (83 female) at a median (IQR) age of 2.6 (0.26–9.24) months and body weight of 5 (3.4–8) kg at BVP with a follow–up of 5.04 (1.6–10.2) years. We used… More >

Vladimiro Vida^*

Congenital Heart Disease, Vol.17, No.1, pp. 1-3, 2022, DOI:10.32604/CHD.2022.019093

Abstract This article has no abstract. More >

MARGARET SIMONIAN^*

BIOCELL, Vol.45, No.6, pp. 1459-1463, 2021, DOI:10.32604/biocell.2021.017369

Abstract Pediatric central nervous system tumors are the most common tumors in children, it constitute 15%–20% of all malignancies in children and are the leading cause of cancer related deaths in children. Proteogenomics is an emerging field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of biomarkers for diagnosis and therapeutic purposes. Integrative proteogenomics analysis of pediatric tumors identified underlying biological processes and potential treatments as well as the functional effects of somatic mutations and copy number variation driving tumorigenesis. More >

Fabrizio Drago^*, Irma Battipaglia, Pietro Paolo Tamborrino, Luigina Porco, Camilla Calvieri, Mario Salvatore Russo, Vincenzo Pazzano, Romolo Remoli, Massimo Stefano Silvetti

Congenital Heart Disease, Vol.16, No.6, pp. 561-572, 2021, DOI:10.32604/CHD.2021.016623

Abstract Background: Cryoablation of accessory pathways (APs) is effective and very safe in children, as previously reported by our group. The aim of this retrospective study was to evaluate the current efficacy of 3D non-fluoroscopic cryoablation of right sided APs in children, comparing results obtained with the Ensite Velocity^TM and the more recent Ensite Precision^TM 3D mapping systems. Methods and Results: From January 2016 to December 2019, 102 pediatric patients [mean age 12.5 ± 2.8, 62 males (61% of total cohort)] with right APs underwent 3D non-fluoroscopic transcatheter cryoablation at our Institution. Fifteen (14.7%) patients had previously undergone catheter ablation. Acute… More >

Ke Zhou¹, Dongyu Li¹, Xintong Zhang², Wensheng Wang¹, Shusen Li¹, Guang Song^2,*

Congenital Heart Disease, Vol.16, No.6, pp. 609-645, 2021, DOI:10.32604/CHD.2021.016396

Abstract Cardioplegia has been widely used to reduce myocardial injury during pediatric cardiac surgery; however, which cardioplegia solution has the best protective effect has not been established. Thus, we compared the myocardial protective effects of different cardioplegia solutions used in pediatric cardiac surgery. Seven databases were searched to identify the relevant randomized controlled trials. A network meta-analysis with a Bayesian framework was conducted. The outcomes included the following biochemical and clinical outcomes: serum concentrations of the creatine kinase-myocardial band at 6 h postoperatively; cardiac troponin I (cTnI) at 4, 12, and 24 h postoperatively; spontaneous beating after declamping; postoperative arrhythmias; inotropic… More >

Mohammadrafie Khorgami¹, Ali Sadeghpour Tabaei^2,*, Elio Caruso^3,*, Silvia Farruggio³, Negar Omidi⁴, Maryam Moradian¹, Behzad Mohammadpour Ahranjani⁵, Zahra Khajali6 and Rahele Zamani¹

Congenital Heart Disease, Vol.16, No.6, pp. 573-584, 2021, DOI:10.32604/CHD.2021.016271

Abstract Background: Most children in need of cardiac pacemakers remain dependent on the function of the permanent from childhood to adulthood. We sought to evaluate and compare the function between epicardial and endocardial pacemakers in pediatric groups with different conditions. Methods: Between 2012 and 2018, this single-canter study evaluated 44 pediatric patients with indications for epicardial or endocardial pacemakers. Results: The 2 groups, at a median age of 5 (0.1–16) years, were compared concerning the characteristics of the leads used (n = 80: bipolar, unipolar, steroid-eluting, and non–steroid-eluting), survival data, and complications. The reason for pacemaker implantation was congenital complete heart… More >

Gabriele Egidy Assenza¹, Biagio Castaldi^2,*, Serena Flocco³, Giovanni Battista Luciani⁴, Giovanni Meliota⁵, Gabriele Rinelli⁶, Ugo Vairo⁵, Silvia Favilli⁷, Board of the Italian Society of Pediatric Cardiology

Congenital Heart Disease, Vol.16, No.5, pp. 427-431, 2021, DOI:10.32604/CHD.2021.016713

Abstract COVID-19 pandemic continues to strike across the world with increasing number of infected patients, severe morbidity and mortality, social life and economy disruption. Universal access to vaccine prophylaxis will be pivotal in controlling this infection and providing individual level protection. However, mismatch between vaccine request and vaccine availability, as well as constraints in logistics of vaccine campaign is creating a transition phase of progressive but still incomplete inclusion of group of individuals in the vaccination process. Selected patients living with chronic and multisystemic disease may present increased propensity of adverse outcome, should Sars-Cov-2 infection develop. In these patients, expedite access… More >

Shamsah Majed Alotaibi¹, Atta-ur-Rahman¹, Mohammed Imran Basheer¹, Muhammad Adnan Khan^2,*

CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 149-165, 2021, DOI:10.32604/cmc.2021.015976

Abstract Epilepsy is a type of brain disorder that causes recurrent seizures. It is the second most common neurological disease after Alzheimer’s. The effects of epilepsy in children are serious, since it causes a slower growth rate and a failure to develop certain skills. In the medical field, specialists record brain activity using an Electroencephalogram (EEG) to observe the epileptic seizures. The detection of these seizures is performed by specialists, but the results might not be accurate due to human errors; therefore, automated detection of epileptic pediatric seizures might be the optimal solution. This paper investigates the detection of epileptic seizures… More >