Laura S. Kverneland^1,2, Peter Kramer², Stanislav Ovroutski²

Congenital Heart Disease, Vol.13, No.2, pp. 181-193, 2018, DOI:10.1111/chd.12570

Abstract Almost fifty years after its first clinical application, the modified Fontan operation is among the most frequently performed procedures in congenital heart disease surgery in children today. The objective of this review is to systematically summarize the international evolution of outcomes in regard to morbidity and mortality of patients with Fontan palliation. All studies published over the past five decades with more than 100 Fontan patients included were screened. In eligible studies, information concerning preoperative patients’ characteristics, Fontan modifications employed, early mortality, long-term survival and frequency of relevant complications was extracted. Ultimately, thirty-one studies published by the largest surgical centers… More >

So Yeon Kim^1,2, Diana S. Wolfe², Cynthia C. Taub²

Congenital Heart Disease, Vol.13, No.2, pp. 203-209, 2018, DOI:10.1111/chd.12546

Abstract Aims: Pregnancy in patients with Marfan’s syndrome (MFS) carries an increased risk of cardiovascular complications, resulting in increased maternal and fetal mortality and morbidity. Literature on MFS pregnant patients is relatively sparse, and there has yet to be a concrete consensus on the management of this unique patient population. The purpose of our paper is to provide a literature review of case reports and studies on MFS during pregnancy (published between 2005 and 2015) and to explore cardiovascular outcomes of patients with MFS.
Methods and Results: Of the 852 women in our review, there were 1112 pregnancies, with an aortic… More >

Robert W. Loar, Cory V. Noel, Hari Tunuguntla, John L. Colquitt, Ricardo H. Pignatelli

Congenital Heart Disease, Vol.13, No.1, pp. 5-15, 2018, DOI:10.1111/chd.12564

Abstract Chemotherapy-induced cardiotoxicity in adults and children is a topic with a growing interest in the cardiology literature. The ability to detect cardiac dysfunction in a timely manner is essential in order to begin adequate treatment and prevent further deterioration. This article aims to provide a review on the myocardial injury process, chemotherapeutic agents that lead to cardiotoxicity, the definition of cardiotoxicity, and the methods of timely detection and treatment. More >

Uri Pollak^1,2,3, David Mishaly^3,4, Gili Kenet^3,5, Amir Vardi^1,3

Congenital Heart Disease, Vol.13, No.1, pp. 16-25, 2018, DOI:10.1111/chd.12557

Abstract Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of heparin therapy. The risk for HIT correlates with the cumulative dosage of heparin exposure. In Fontan patients, recurrent systemic anticoagulation, traditionally with heparin, is used to alleviate the thrombotic complications that may occur postoperatively when the venous pressure rises and the systemic venous flow into the pulmonary arteries becomes sluggish, putting them at increased risk. As a pressure gradient-dependent circulation, elevation in systemic venous pressure, most often by venous thrombosis, contributes to circuit failure. Therefore, when HIT complicates patients after the Fontan procedure, it is associated with a high thrombotic morbidity and… More >

Mahmoud Alsalehi¹, Aamir Jeewa¹, Andrea Wan¹, Juan Contreras², Shi‐Joon Yoo³, Jessica A. Laks¹

Congenital Heart Disease, Vol.14, No.6, pp. 901-923, 2019, DOI:10.1111/chd.12842

Abstract Left main coronary artery ostial atresia (LMCAOA) is a rare congenital anomaly of the coronary arteries. The published literature regarding the current diagnostic and manage‐ ment recommendations are limited. We present three case series of LMCAOA from our institution, including one with a unique association with anomalous origin of left coronary artery (LCA) from pulmonary artery. In addition, this report includes a review of 50 pedi‐ atric and 43 adult cases from literature. The majority of the patients were symptomatic. Sudden cardiac death occurred in 10% of pediatric patients and 7% of adult patients. Almost half of pediatric patients had… More >

Munes Fares¹, Paul J. Critser², Maria J. Arruda¹, Carolyn M. Wilhelm¹, Mantosh S. Rattan³, Sean M. Lang^2,4, Tarek Alsaied^2,4

Congenital Heart Disease, Vol.14, No.6, pp. 1166-1175, 2019, DOI:10.1111/chd.12840

Abstract Pharmacologic stress cardiovascular magnetic resonance (PSCMR) is a wellestablished and reliable diagnostic tool for evaluation of coronary artery disease in the adult population. Stress imaging overall and PSCMR in particular is less utilized in the pediatric population with limited reported data. In this review, we highlight the potential use of PSCMR in specific pediatric cohorts with congenital and acquired heart disease, and we review the reported experience. A suggested protocol is presented in addition to two case examples of patients with Kawasaki disease where PSCMR aided decision making. More >

Andrew D. Spearman¹, Steven J. Kindel¹, Ronald K. Woods², Salil Ginde^1,3

Congenital Heart Disease, Vol.14, No.6, pp. 1199-1206, 2019, DOI:10.1111/chd.12828

Abstract Background: Hypoxia is a common and sometimes severe morbidity of single ven‐ tricle congenital heart disease (CHD). Creation of an arteriovenous fistula (AVF) is occasionally performed for patients after superior or total cavopulmonary connec‐ tion (SCPC or TCPC) in an attempt to improve oxygen saturations. Despite previ‐ ous reports, AVF creation is a rare palliation with inadequately defined benefits and risks. We sought to determine changes in peripheral oxygen saturation (SpO₂) and risk of adverse event after AVF creation in children with single ventricle CHD at our institution.
Methods: We conducted a retrospective chart review of patients with a history… More >

Hongping Wu¹, Yuling Liu^{1, *}, Jingwen Wang²

CMC-Computers, Materials & Continua, Vol.63, No.3, pp. 1309-1321, 2020, DOI:10.32604/cmc.2020.010172

Abstract Text classification has always been an increasingly crucial topic in natural language processing. Traditional text classification methods based on machine learning have many disadvantages such as dimension explosion, data sparsity, limited generalization ability and so on. Based on deep learning text classification, this paper presents an extensive study on the text classification models including Convolutional Neural Network-Based (CNN-Based), Recurrent Neural Network-Based (RNN-based), Attention Mechanisms-Based and so on. Many studies have proved that text classification methods based on deep learning outperform the traditional methods when processing large-scale and complex datasets. The main reasons are text classification methods based on deep learning… More >

Soham Dasgupta, Glen Iannucci, Chad Mao, Martha Clabby, Matthew E. Oster

Congenital Heart Disease, Vol.14, No.5, pp. 868-877, 2019, DOI:10.1111/chd.12835

Abstract Myocarditis has a variable clinical presentation and there is still debate regarding accurate diagnostic criteria. Adding to the controversy surrounding this diagnosis, there is no clear consensus for the treatment or ongoing follow‐up of patients with myocarditis. All of this makes the diagnosis and management of myocarditis a par‐ ticular challenge in the pediatric population. Furthermore, the literature with respect to this topic is dynamic and ever‐changing. In this review article, we aim to review and summarize the common clinical presentations of myocarditis, along with the latest recommendations for diagnostic criteria, treatment, and follow‐up of patients with myocarditis. More >

Kokoette Effiong¹, Jing Hu¹, Caicai Xu¹, Tao Tang¹, Haomin Huang², Jiangning Zeng^1,3, Xi Xiao^1,3,4,*

Journal of Renewable Materials, Vol.8, No.5, pp. 461-483, 2020, DOI:10.32604/jrm.2020.09111

Abstract The use of agricultural straw for algal bloom control has been studied for more than 30 years. In this article, we have reviewed the promising potentials of using agricultural straw as source of anti-algal agents, including the effectiveness of each major straw type so far used in this regard, and the investigated algal species. Various pre-treatment methods have also been widely reviewed. Signifi- cant progress has been made in natural product chemistry and molecular biology with regards to agricultural straw, especially in relation to the extraction of antialgal allelochemicals, degradation processes of agricultural straws and the mechanisms through which these… More >