Ryan Daigle¹, Ilene Staff², Joseph Tortora², Tara McLaughlin Proto^3,*, Kevin Pinto³, Rosa Negron², Jonathan Earle⁴, Joseph Wagner,³

Canadian Journal of Urology, Vol.32, No.3, pp. 189-198, 2025, DOI:10.32604/cju.2025.063773 - 27 June 2025

Abstract Introduction: We examined the pathology and safety outcomes associated with the extent of pelvic lymph node dissection in patients with high-risk prostate cancer undergoing radical prostatectomy. Materials and Methods: We retrospectively identified men with prostate cancer who underwent robot-assisted radical prostatectomy with pelvic lymph node dissection between May 2016 and September 2021. Cases were categorized using Current Procedural Terminology (CPT) codes (38571) for extended lymph node dissection and super-extended lymph node dissection (38572). Using logistic regression, we compared the groups on a number of factors, including recurrence. Results: Super-extended lymph node dissection had significantly higher median… More >

LUCIANA SABOYA^1,2, KEINI BUOSI¹, TIAGO SILVA², ELAINE CANDIDO¹, JOSIANE MORARI³, LICIO A. VELLOSO³, SHAHROKH F. SHARIAT^4,5,6,7, MARCUS V. SADI², LEONARDO O. REIS^1,8,9,*

Oncology Research, Vol.33, No.6, pp. 1495-1503, 2025, DOI:10.32604/or.2025.061812 - 29 May 2025

Abstract Objective: To determine the safety and the role of modulating cytokines and proteases in the immune response to intravesical Bacillus Calmette-Guérin (BCG) when primed with systemic intradermal BCG. Methods: Phase 1 and mechanistic longitudinal, prospective, single-blind randomized study (NCT04806178). Twenty-one non-muscle invasive urothelial bladder cancer patients undergoing intravesical adjuvant BCG after transurethral resection of bladder tumor (TURBT) in a teaching hospital between September 2021 and April 2023 were randomized to 0.1 mL of intradermal BCG vaccine or placebo (0.9% saline) administered 15 days before the start of intravesical BCG therapy. Blood samples were evaluated mechanistically… More >

Yang Su^1,*, Xianrang Shi¹, Tinglun Song²

CMC-Computers, Materials & Continua, Vol.83, No.3, pp. 5831-5848, 2025, DOI:10.32604/cmc.2025.064036 - 19 May 2025

Abstract Ensuring that autonomous vehicles maintain high precision and rapid response capabilities in complex and dynamic driving environments is a critical challenge in the field of autonomous driving. This study aims to enhance the learning efficiency of multi-sensor feature fusion in autonomous driving tasks, thereby improving the safety and responsiveness of the system. To achieve this goal, we propose an innovative multi-sensor feature fusion model that integrates three distinct modalities: visual, radar, and lidar data. The model optimizes the feature fusion process through the introduction of two novel mechanisms: Sparse Channel Pooling (SCP) and Residual Triplet-Attention… More >

Anna Chiara Uggenti¹, Giorgio Rech², Raffaella Gerboni^2,*, Gianmario Ledda², Amedeo Aliberti¹, Claudia Vivalda³, Emanuela Bruno², Andrea Carpignano²

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.4, pp. 757-782, 2025, DOI:10.32604/fdmp.2025.062347 - 06 May 2025

Abstract The paper presents an innovative approach to studying the reuse of a decommissioned natural gas production platform for the seasonal storage and extraction of a hydrogen-methane (H₂-CH₄) mixture from a depleted reservoir. The reuse plan involves removing outdated equipment from the platform’s decks while retaining essential components such as wellheads and separators. Exploiting a depleted reservoir for the injection of an H₂-CH₄ mixture requires a thorough understanding of its specific characteristics. This paper focuses on the engineering approach adopted in the basic design phase for such a conversion, providing recommendations and HSE guidelines. Given the hazardous… More >

Wenyin Yang¹, Zhijie Xu², Yang Liu^2,*

Journal of Psychology in Africa, Vol.35, No.1, pp. 43-49, 2025, DOI:10.32604/jpa.2025.065880 - 30 April 2025

Abstract Drawing upon the Conservation of Resources theory, this study investigated the relationship between proactive personality and strengths use, as well as the mediating role of psychological safety and the moderating role of exploitative leadership within this relationship. Data were collected from 368 employees (females = 57.61%; mean age = 32.35; SD = 6.31) working in various organizations in China at two points in time with a two-week interval. We conducted structural equation modeling and a moderated mediation path analysis to test our hypotheses. The results demonstrated that proactive personality is positively related to strengths use More >

Huan Ma¹, Jinmei Zou^1,*, Ying Zhong²

Journal of Psychology in Africa, Vol.35, No.1, pp. 21-27, 2025, DOI:10.32604/jpa.2025.065766 - 30 April 2025

Abstract This study explored the mediating role of moral courage in the relationship between emotional intelligence and perceptions of patient safety competence among nursing students in clinical practice. The study sample comprised 220 nursing students from a teaching hospital (female = 93.6%; mean age = 20.64 years, SD = 1.78 years). Nursing students completed standardized measures of Emotional Intelligence Scale, the Moral Courage Scale, and the Health Professional Education in Patient Safety Survey. Following hierarchical regression analysis and bootstrap analysis, the results showed that emotional intelligence and moral courage significantly predicted high levels of the perceptions More >

Demirhan Örsan Demir^1,*, Yusuf Gökkurt¹, Salih Bürlükkara², Turgay Kaçan¹, Ali Kaan Yıldız¹, Ufuk Bozkurt², Tolga Karakan¹

Canadian Journal of Urology, Vol.32, No.2, pp. 111-118, 2025, DOI:10.32604/cju.2025.063970 - 30 April 2025

Abstract Introduction: Surgeons typically prefer 270 µm and 272 µm laser probes in retrograde intrarenal surgery (RIRS) due to the reduced deflection capacity of flexible ureterorenoscopes when using larger probe diameters. This study aims to investigate the effects of 272 and 365 µm holmium laser probes on operative time, clinical efficacy, and complication rates in RIRS. Materials and Methods: A total of 285 patients with proximal ureteral or kidney stones who met the inclusion criteria were enrolled in the study. Patients were divided into two groups based on laser probe thickness: 272 µm and 365 µm. Stone-free… More >

Lieping Zhang^1,2, Hao Ma¹, Jiancheng Huang³, Cui Zhang^4,*, Xiaolin Gao²

CMC-Computers, Materials & Continua, Vol.83, No.2, pp. 2245-2265, 2025, DOI:10.32604/cmc.2025.061519 - 16 April 2025

Abstract Detecting individuals wearing safety helmets in complex environments faces several challenges. These factors include limited detection accuracy and frequent missed or false detections. Additionally, existing algorithms often have excessive parameter counts, complex network structures, and high computational demands. These challenges make it difficult to deploy such models efficiently on resource-constrained devices like embedded systems. Aiming at this problem, this research proposes an optimized and lightweight solution called FGP-YOLOv8, an improved version of YOLOv8n. The YOLOv8 backbone network is replaced with the FasterNet model to reduce parameters and computational demands while local convolution layers are added.… More >

He Zhang^1,2,*, He-Qing Mu^2,*, Xiao Zhang³, He Zhang², Yuedong Yang⁴

Structural Durability & Health Monitoring, Vol.19, No.3, pp. 499-530, 2025, DOI:10.32604/sdhm.2025.059070 - 03 April 2025

Abstract Safety evaluation of a bridge under Moving Abnormal Indivisible Loads (MAILs) directly relates to whether an oversized and/or overweight Large-Cargo Transportation (LCT) vehicle is permitted to pass the bridge. Safety evaluation can be updated by fusing bridge inspection data and load test data, but there are two fundamental difficulties in updating. The first difficulty is to develop an updating scheme to utilize the unstructured inspection data. The second difficulty is to develop a successive updating scheme using load test data based on the previous updating results of the inspection data. This paper proposed a framework,… More >

Badrinath R. Konety^1,*, Yair Lotan², Amanda Myers³

Canadian Journal of Urology, Vol.32, No.1, pp. 29-36, 2025, DOI:10.32604/cju.2025.064710 - 20 March 2025

Abstract Introduction: Non–muscle-invasive bladder cancer (NMIBC) is a common malignancy worldwide. While Bacillus Calmette-Guérin (BCG) is standard of care for treatment for most patients with high-risk NMIBC, many will either not respond to BCG initially or will eventually develop BCG-unresponsive disease. A treatment option in BCG-unresponsive disease is nadofaragene firadenovec-vncg (Adstiladrin), a nonreplicating adenoviral vector–based gene therapy approved by the US Food and Drug Administration (FDA) for the treatment of adults with high-risk BCG-unresponsive NMIBC with carcinoma in situ with or without papillary tumors. Objective: To review safety outcomes of participants who received the FDA-approved dose… More >