Batyrkhan Omarov^1,*, Sergazi Narynov², Zhandos Zhumanov²

CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5105-5122, 2023, DOI:10.32604/cmc.2023.034655

Abstract Clinical applications of Artificial Intelligence (AI) for mental health care have experienced a meteoric rise in the past few years. AI-enabled chatbot software and applications have been administering significant medical treatments that were previously only available from experienced and competent healthcare professionals. Such initiatives, which range from “virtual psychiatrists” to “social robots” in mental health, strive to improve nursing performance and cost management, as well as meeting the mental health needs of vulnerable and underserved populations. Nevertheless, there is still a substantial gap between recent progress in AI mental health and the widespread use of these solutions by healthcare practitioners… More >

Emma Payne^1,2, Thomas Wilson^2,3, Marjan Haghighi^1,4, Zoe McCallum^2,3, Yves d’Udekem⁵, Julian Ayer^1,4,*

Congenital Heart Disease, Vol.17, No.6, pp. 617-639, 2022, DOI:10.32604/chd.2022.024775

Abstract Background: Patients born with a single ventricle circulation commonly experience growth failure in early life, which is associated with adverse outcomes in infancy. However, associations between bodyweight or weight trajectory and clinical outcome post-Fontan procedure are yet to be determined. Methods: On the 1st of July 2021, a systematic review was performed in MEDLINE, EMBASE, the Cochrane Library, and Scopus of studies of patients with clinical outcome data post-Fontan procedure and association with bodyweight. Quality of studies was evaluated by Newcastle–Ottawa scale for cohort studies and Joanna Briggs Institute tool for cross-sectional studies. Results: Of 527 studies that underwent title… More >

YINGHUI GAO, DENGTAI WEN^*, SHIJIE WANG, JINGFENG WANG

BIOCELL, Vol.47, No.1, pp. 41-49, 2023, DOI:10.32604/biocell.2022.022689

Abstract Presenilin (Psn) protein is associated with organismal aging. Mutations in the Psn gene may lead to Alzheimer’s disease (AD), dilated cardiomyopathy (DCM), and many age-dependent degenerative diseases. These diseases seriously affect the quality of life and longevity of the population and place a huge burden on health care and economic systems around the world. Humans have two types of Psn, presenilin-1 (PSEN1) and presenilin-2 (PSEN2). Mutations in the genes encoding PSEN1, PSEN2, and amyloid precursor protein (APP) have been identified as the major genetic causes of AD. Psn is a complex gene strongly influenced by genetic and environmental factors. The… More >

Lu Zhang¹, Jiarong Mao¹, Yuting An¹, Tianshuo Zhang¹, Jixin Ma², Chen Feng³, Xiaoyi Zhou^1,*

CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 1161-1181, 2023, DOI:10.32604/cmc.2023.032452

Abstract Government information sharing (GIS) refers to that act of required or provided for duty government information, commercial information and public welfare information, and it is a basic issue of government services. However, the existing GIS has low transparency and is lack of flexibility between different departments. Aiming at such problems, this paper takes blockchain as a solusion, and systematically summarizes the development of digital GIS, the advantages and challenges of blockchain and its theoretical research and practical applications. Specifically, it reviews e-government interactive structure, big data and other solutions, analyses their imperfections, and puts forward blockchain-based solutions. The blockchain improves… More >

Ying Yang^1,#, Tingting Lv^2,#, Siyuan Li¹, Ping Zhang^1,2,*

Congenital Heart Disease, Vol.17, No.5, pp. 557-567, 2022, DOI:10.32604/CHD.2021.017292

Abstract Background: T-wave alternans (TWA) is a risk factor of ventricular arrhythmias or sudden cardiac death (SCD) in patients with ischemic cardiomyopathy. Nevertheless, the relationship between TWA and adverse cardiac events (ACE) in patients with congenital long QT syndrome (LQT) remains controversial. Methods: A systematic electronic search of PubMed, Embase and the Cochrane Library was conducted from database inception dates to 28 April 2021 and assessed the relationship between TWA and ACE in patients with LQTS. Sub-group analysis evaluated the association between microvolt TWA (MTWA) and ACE in different monitoring models and ECGlead numbers. Results: A pooled analysis of seven studies… More >

RAHELEH TORABI¹, ABBAS ALI REZVANIPOUR², HADI ESMAEILI GOUVARCHINGHALEH³, REZA RANJBAR^4,*, MOHAMMAD HEIAT^2,*

BIOCELL, Vol.46, No.12, pp. 2537-2557, 2022, DOI:10.32604/biocell.2022.021373

Abstract Ochratoxin A (OTA), one of the most dangerous mycotoxins for human health, has been subjected to numerous studies for separation and detection in minimal amounts. Aptamers as novel recognition elements have been employed to fabricate ultrasensitive biosensors for the detection of OTA and designing delicate analytical tools. This review attempted to comprehensively examine all reported aptamer-based detection and separation platforms for ochratoxin. The most relevant databases were considered to discover all specific aptamers for dealing with OTA. Aptamer-based detection and separation devices specified for OTA were searched for, analyzed, discussed, and classified based on their specifications. The optical aptasensors have… More >

M. K. Shilpa¹, Md Abdul Raheman², Abdul Aabid^3,*, Muneer Baig³, R. K. Veeresha⁴, Nagesh Kudva⁴

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.1, pp. 187-206, 2023, DOI:10.32604/fdmp.2022.020351

Abstract Conventional refrigeration processes release ammonia and freon into the atmosphere, which results in global warming. These problems may be overcome by using thermoelectric modules because of the absence of coolants or refrigerants in these systems. However, the cooling performances of such modules are relatively small in comparison to those of conventional refrigerators. In this paper, the working principles of thermoelectric modules are discussed together with a review of different relevant aspects, namely: the thermoelectric materials, and their mechanical properties used to build thermoelectric devices, different types of thermoelectric devices available on the market, mathematical modeling of thermoelectric materials, and various… More >

Dariimaa Ganbat^1,2, Bat-Erdene Jugder³, Lkhamaa Ganbat⁴, Miki Tomoeda⁵, Erdenetsogt Dungubat^2,6, Ambaga Miyegombo⁷, Gantsetseg Garmaa⁸, Yoshihisa Takahashi⁶, Ryuji Fukuzawa⁶, Ichiro Mori⁶, Takayuki Shiomi⁶, Akinori Nakata⁹, Yasuhiko Tomita^6,*

Oncologie, Vol.24, No.2, pp. 195-225, 2022, DOI:10.32604/oncologie.2022.022299

Abstract Most cancer cells overexpress the anti-apoptotic protein survivin and display redox dysregulation originating from genotypic and phenotypic alterations. These disturbances contribute to the uncontrolled proliferation, invasion, and chemoresistance of cancer cells, yet they also represent a specific vulnerability that could be exploited therapeutically in selected tumors. YM155 (sepantronium bromide) is a naphthoquinone-containing imidazolebased compound that selectively inhibits survivin expression at the transcriptional and post-transcriptional levels. Here, we performed a systematic review and meta-analysis of clinical studies in which YM155 was administered as monotherapy or combination therapy for patients with cancer. We assessed fully or partially reported clinical outcomes and pharmacological… More >

MARLA DE CERQUEIRA ALVES¹, MONISE OLIVEIRA SANTOS¹, NASSIB BEZERRA BUENO¹, ORLANDO ROBERTO PIMENTEL DE ARAÚJO², MARÍLIA OLIVEIRA FONSECA GOULART^2,3,4, FABIANA ANDRÉA MOURA^1,5,*

BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407

Abstract

The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

Jingkang Zhang¹, Shiyuan Zhang¹, Changhao Niu^1,2, Jiang Jiang^1,2, Haijun Sun^1,2,*

Phyton-International Journal of Experimental Botany, Vol.91, No.8, pp. 1601-1616, 2022, DOI:10.32604/phyton.2022.020323

Abstract Soil degradation threatens the forest sustainable productivity, particularly in afforestation system. Biochar derived from agroforestry waste or biomass can potentially improve the degraded forest soil and promote the tree growth. To expand the application of biochar for forestry productivity improvement, we here reviewed the effects and the underlying mechanisms of biochar on the degraded forest soil and tree growth. Totally 96 studies that conducted from pot to field investigations in China were summarized. The result suggested that biochar generally exerted positive effects on restoration of degraded forest soil such as that with compaction, acidification or soil erosion, which are mainly… More >