Xin Zou¹, Jieyu Zhang¹, Ting Cheng¹, Yangyang Guo¹, Xiao Han¹, Han Liu¹, Yuxing Qin¹, Jie Li², Dabing Xiang^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 699-712, 2024, DOI:10.32604/phyton.2024.048469

Abstract To mitigate the wastage of seed resources and reduce the usage of pesticides and fertilizers, seed coating agents have gained popularity. This study employs single-factor and multi-index orthogonal experimental design methods to investigate the seed coating formula and physical properties of Tartary buckwheat. The specific effects of each component on Tartary buckwheat seed germination are analyzed. The findings reveal that the seed coating agent formulated with 1.5% polyvinyl alcohol, 0.15% sodium alginate, 0.2% op-10, 0.1% polyacrylamide, 8% colorant, 3% ammonium sulfate, 1% potassium dihydrogen phosphate, and 0.15% carbendazim exhibits the most effective coating. It demonstrates optimal physical properties and promotes… More >

Siyuan Liu^1,*, Jinying Huang², Jiancheng Ma¹, Licheng Jing², Yuxuan Wang²

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 761-777, 2024, DOI:10.32604/cmc.2024.049484

Abstract Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems, such as relatively ideal speed conditions and sample conditions. In engineering practice, the rotational speed of the machine is often transient and time-varying, which makes the sample annotation increasingly expensive. Meanwhile, the number of samples collected from different health states is often unbalanced. To deal with the above challenges, a complementary-label (CL) adversarial domain adaptation fault diagnosis network (CLADAN) is proposed under time-varying rotational speed and weakly-supervised conditions. In the weakly supervised learning condition, machine prior information is used for sample annotation via cost-friendly complementary label learning.… More >

Jiajun Yan, Ying Zhou^*, Anchen Dai, Tao Wang

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 563-580, 2024, DOI:10.32604/cmc.2024.048922

Abstract As an emerging network paradigm, the software-defined network (SDN) finds extensive application in areas such as smart grids, the Internet of Things (IoT), and edge computing. The forwarding layer in software-defined networks is susceptible to eavesdropping attacks. Route hopping is a moving target defense (MTD) technology that is frequently employed to resist eavesdropping attacks. In the traditional route hopping technology, both request and reply packets use the same hopping path. If an eavesdropping attacker monitors the nodes along this path, the risk of 100% data leakage becomes substantial. In this paper, we present an effective route hopping approach, called two-day… More >

Xue Zhao, Shaojun Tao, Hongying Tang, Jiang Wang^*, Baoqing Li^*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1335-1351, 2024, DOI:10.32604/cmc.2024.047996

Abstract In recent years, target tracking has been considered one of the most important applications of wireless sensor network (WSN). Optimizing target tracking performance and prolonging network lifetime are two equally critical objectives in this scenario. The existing mechanisms still have weaknesses in balancing the two demands. The proposed heuristic multi-node collaborative scheduling mechanism (HMNCS) comprises cluster head (CH) election, pre-selection, and task set selection mechanisms, where the latter two kinds of selections form a two-layer selection mechanism. The CH election innovatively introduces the movement trend of the target and establishes a scoring mechanism to determine the optimal CH, which can… More >

Jiao Wang, Bin Wu^*, Hongying Zhang

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 143-160, 2024, DOI:10.32604/cmc.2023.046011

Abstract Deep multi-view subspace clustering (DMVSC) based on self-expression has attracted increasing attention due to its outstanding performance and nonlinear application. However, most existing methods neglect that view-private meaningless information or noise may interfere with the learning of self-expression, which may lead to the degeneration of clustering performance. In this paper, we propose a novel framework of Contrastive Consistency and Attentive Complementarity (CCAC) for DMVsSC. CCAC aligns all the self-expressions of multiple views and fuses them based on their discrimination, so that it can effectively explore consistent and complementary information for achieving precise clustering. Specifically, the view-specific self-expression is learned by… More >

KARAN WADHWA¹, PAYAL CHAUHAN¹, SHOBHIT KUMAR², RAKESH PAHWA^3,*, RAVINDER VERMA⁴, RAJAT GOYAL⁵, GOVIND SINGH¹, ARCHANA SHARMA⁶, NEHA RAO³, DEEPAK KAUSHIK^1,*

Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

NILAM BHUSARE, MAUSHMI KUMAR^*

Oncology Research, Vol.32, No.5, pp. 849-875, 2024, DOI:10.32604/or.2024.047042

Abstract Glioblastoma, the most aggressive form of brain tumor, poses significant challenges in terms of treatment success and patient survival. Current treatment modalities for glioblastoma include radiation therapy, surgical intervention, and chemotherapy. Unfortunately, the median survival rate remains dishearteningly low at 12–15 months. One of the major obstacles in treating glioblastoma is the recurrence of tumors, making chemotherapy the primary approach for secondary glioma patients. However, the efficacy of drugs is hampered by the presence of the blood-brain barrier and multidrug resistance mechanisms. Consequently, considerable research efforts have been directed toward understanding the underlying signaling pathways involved in glioma and developing… More > Graphic Abstract

SANDRA STICKLER, BARBARA RATH, GERHARD HAMILTON^*

Oncology Research, Vol.32, No.5, pp. 799-805, 2024, DOI:10.32604/or.2024.045356

Abstract Pancreatic cancer has a dismal prognosis due to late detection and lack of efficient therapies. The Kirsten rat sarcoma virus (KRAS) oncogene is mutated in up to 90% of all pancreatic ductal adenocarcinomas (PDACs) and constitutes an attractive target for therapy. However, the most common KRAS mutations in PDAC are G12D (44%), G12V (34%) and G12R (20%) that are not amenable to treatment by KRAS G12C-directed cysteine-reactive KRAS inhibitors such as Sotorasib and Adagrasib that exhibit clinical efficacy in lung cancer. KRAS G12C mutant pancreatic cancer has been treated with Sotorasib but this mutation is detected only in 2%–3% of… More >

XIAOXI WANG¹, YANFEI JIA², QIANG LI², QIANG YANG², YINGFENG LIU¹, BEIFENG WEI¹, XIANG NIU¹, YINJIE ZHANG¹, XIAODONG LUO², ZIYU ZHAO^1,*, PENG WANG^1,*

Oncology Research, Vol.32, No.5, pp. 933-941, 2024, DOI:10.32604/or.2023.042581

Abstract MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by in situ hybridization. Transfection of the miR-200b-3p inhibitor and small interfering-RECK (si-RECK) was verified by qPCR. GH3 cell viability and proliferation… More >

Dawei Ruan¹, Mingwei Hu^1,2,3,4,5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 821-844, 2024, DOI:10.32604/cmes.2024.048392

Abstract The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale, multifunctional, and complex orientations. The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units, and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts, leading to variations in the dynamic response of the foundation. The high-frequency units yield significantly diverse outcomes under different startup conditions and times, resulting in failure to meet operational requirements, influencing the normal function of the tunnel, and causing harm to the foundation structure, personnel, and property in severe cases. This article… More >