XIAOXI WANG¹, YANFEI JIA², QIANG LI², QIANG YANG², YINGFENG LIU¹, BEIFENG WEI¹, XIANG NIU¹, YINJIE ZHANG¹, XIAODONG LUO², ZIYU ZHAO^1,*, PENG WANG^1,*

Oncology Research, Vol.32, No.5, pp. 933-941, 2024, DOI:10.32604/or.2023.042581

Abstract MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by in situ hybridization. Transfection of the miR-200b-3p inhibitor and small interfering-RECK (si-RECK) was verified by qPCR. GH3 cell viability and proliferation… More >

Dawei Ruan¹, Mingwei Hu^1,2,3,4,5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 821-844, 2024, DOI:10.32604/cmes.2024.048392

Abstract The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale, multifunctional, and complex orientations. The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units, and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts, leading to variations in the dynamic response of the foundation. The high-frequency units yield significantly diverse outcomes under different startup conditions and times, resulting in failure to meet operational requirements, influencing the normal function of the tunnel, and causing harm to the foundation structure, personnel, and property in severe cases. This article… More >

Guogang Gao¹, Lei Xu¹, Tianpeng Huang^2,*, Xuliang Zhao¹, Lihua Huang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 305-323, 2024, DOI:10.32604/cmes.2024.047899

Abstract The Rotary Inverted Pendulum (RIP) is a widely used underactuated mechanical system in various applications such as bipedal robots and skyscraper stabilization where attitude control presents a significant challenge. Despite the implementation of various control strategies to maintain equilibrium, optimally tuning control gains to effectively mitigate uncertain nonlinearities in system dynamics remains elusive. Existing methods frequently rely on extensive experimental data or the designer’s expertise, presenting a notable drawback. This paper proposes a novel tracking control approach for RIP, utilizing a Linear Quadratic Regulator (LQR) in combination with a reduced-order observer. Initially, the RIP system is mathematically modeled using the… More >

SAIFEI XIE^1,2,4, HUI XIE^2,*, JINCAI GUO³, JIN TAN⁴, YULIN YU¹, MINYI ZHANG¹, SHANG WEN¹

BIOCELL, Vol.48, No.4, pp. 591-599, 2024, DOI:10.32604/biocell.2024.046691

Abstract Background: Puerarin (Pue) has been reported to be a natural active ingredient with multiple antifibrotic properties. This work aimed at exploring the function of Pue in oral submucous fibrosis (OSF) treatment. Methods: Human oral mucosa fibroblasts (hOMF) were induced with transforming growth factor beta1 (TGF-β1) and intervened with Pue. Expressions of fibrosis-related markers were analyzed by Western blot and IF staining. Cell viability was characterized by the CCK-8 assay. Expressions of miR-30 family members were quantified by qRT-PCR. The correlation between fibroblast activation protein (FAP) and miR-30 family expression was evaluated by the Pearson correlation coefficient. Bioinformatics prediction and dual-luciferase… More > Graphic Abstract

Liting Jia¹, Xiao Han¹, Cuixia Qiao², Gang Zhao², Yanzhi Xia¹, Zhixin Xue^1,*

Journal of Renewable Materials, Vol.12, No.3, pp. 427-441, 2024, DOI:10.32604/jrm.2023.044310

Abstract Ba²⁺ pre-crosslinked carrageenan fiber (Ba/CAF) was prepared by adding a small amount of Ba²⁺ to the carrageenan (CA) solution as the spinning solution. Ba/CAF-n/A, Ba/CAF-n/B and Ba/CAF-n/C were prepared with ethanol solution (combine A), high concentration BaCl₂ solution (combine B) and low concentration BaCl₂ solution (combine C), as coagulation bath and stretch bath, respectively. The combination of coagulation bath and stretch bath suitable for Ba²⁺ pre-crosslinking wet spinning was screened. The results showed that Ba²⁺ can induce the birefringence of the CA molecular chain, and the Ba²⁺ pre-crosslinking effect is the best when the CA mass fraction is 8.0 wt%.… More > Graphic Abstract

Feng Sheng^1,*, Chen Kong², Chao Li³

International Journal of Mental Health Promotion, Vol.26, No.3, pp. 221-228, 2024, DOI:10.32604/ijmhp.2024.030209

Abstract Objective: This study was conducted to explore the relationships among sedentary behavior (SB), electronic product addiction (EPA), and depression (D) in adolescents during the COVID-19 epidemic. Methods: A total of 604 adolescents (including 309 girls and 295 boys aged 12–18) were selected from Qufu City, Shandong Province, China for three rounds of investigation. The model was constructed using AMOS 23.0 software, and cross-lagged analysis was conducted. Results: SB at T1 can significantly positively predict SB and EPA at T2 (p < 0.05). EPA at T1 can significantly positively predict SB and D at T2 (p < 0.05). Physical activity level… More >

JIANGBO WANG^*

Journal of Polymer Materials, Vol.36, No.4, pp. 381-389, 2019, DOI:10.32381/JPM.2019.36.04.7

Abstract In this study, a novel flame retardant polyvinylphenylsilsesquioxane (PVP) was added into epoxy resin (EP) to prepare EP/PVP (FREP) composites. The results of cone calorimeter measurement showed that in comparison with virgin EP, the peak heat release rate (PHRR) and total heat release (THR) of FREP were reduced by 27.3% and 10.4%, respectively. Moreover, the thermal degradation behavior of FREP was studied by the Kissinger and Ozawa-Flynn-Wall methods. The results suggested that the addition of PVP greatly enhanced the thermal stability of EP in the final stage, which could be attributed to that the branched silicone with vinyl and phenyl… More >

RAJKUMAR SINGH RAWAT^1,2, MEENU TALWAR^1,*, RAJENDRA KUMAR DIWAN², AJAY KUMAR TYAGI¹

Journal of Polymer Materials, Vol.38, No.3-4, pp. 281-294, 2021, DOI:10.32381/JPM.2021.38.3-4.9

Abstract In the present paper,boron based diluent was synthesized and incorporated in to a Ultraviolet (UV) radiation curable epoxy coating composition comprising of phosphorus based initiator (Trimethylbenzoyl diphenyl phosphine oxide) for enhancing its flame retardant property. The boron based diluent was synthesized by thermal polymerization technique. The presence of boron and phosphorus on the coating surface was confirmed by Energy Dispersive X-Ray (EDX) and X-ray photoelectron spectroscopy (XPS) techniques and functionality was determination by Fourier Transform Infra-Red (FTIR) and proton/boron NMR spectroscopy technique. The flame retardency property of the coating composition was confirmed by determining limiting oxygen index,vertical burning test, rate… More >

CANSU ULKER TURAN^1,*, YUKSEL GUVENILIR¹

Journal of Polymer Materials, Vol.38, No.3-4, pp. 271-280, 2021, DOI:10.32381/JPM.2021.38.3-4.8

Abstract Rice husk ash is a side-product of rice production; thus, it is a cheap, abundant, and renewable material, and utilized as an enzyme carrier to immobilize Candida antarctica lipase B. In this study, Candida antarctica lipase B immobilized onto rice husk ashes was used to catalyze ring opening polymerization of 16-membered lactone, ω-pentadecalactone. In order to determine the best polymerization conditions for highest molar mass polymer, reactions were proceeded at various temperatures and time periods. The best reaction conditions were obtained as 80°C and 6 hours (M_n = 34255 g mol^-1). Molecular structure of this polymer sample was confirmed via… More >

SOBHA KOTA^*, RATNAKUMARI ANANTHA, VAYUNANDANA RAO GOVADA, PRADEEP DUMPALA

Journal of Polymer Materials, Vol.40, No.3-4, pp. 285-303, 2023, DOI:10.32381/JPM.2023.40.3-4.10

Abstract The exoskeleton of marine shrimp contains a natural, biocompatible polymer chitin, which is dumped as a waste. The study proposes the sustainable single-pot-extraction of chitosan from the waste and its use in the fabrication of wound-dressings, and thus leverage its piezoelectric, antioxidant, hypoglycaemic and medicinal properties in wound-healing. The Fourier transform infrared spectrum revealed that marine chitosan contains functional groups with N-O, O-H, and CO stretching. Scanning electron micrographs demonstrated the spherical and mesoporous structures of the extracted chitosan. X-ray diffraction analysis showed a semi-crystalline phase of chitosan particles with a mean size of 28.9 nm. The film prepared with… More >