Hamed Alqahtani¹, Gulshan Kumar^2,*

CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.077367 - 09 April 2026

Abstract Large Language Models (LLMs) are becoming integral components of modern cybersecurity ecosystems, simultaneously strengthening defensive capabilities while giving rise to a new class of Artificial Intelligence–Generated Content (AIGC)-driven threats. This PRISMA-guided systematic review synthesises 167 peer-reviewed studies published between 2022 and 2025 and proposes a unified threat–defence–evaluation taxonomy as a central analytical framework to consolidate a previously fragmented body of research. Guided by this taxonomy, the review first examines AIGC-enabled threats, including automated and highly personalised phishing, polymorphic malware and exploit generation, jailbreak and adversarial prompting, prompt-injection attack vectors, multimodal deception, persona-steering attacks, and large-scale… More >

Shuwen Sun^1,2,3,4,#, Jingcheng Zhang^1,2,3,#, Zongtai Zheng^5,#, Yajuan Hao^1,3, Tianyuan Xu^1,2,3, Ji Liu^1,3, Liang Sun², Aimin Wang², Yadong Guo^1,3, Shiyu Mao^1,3, Xu Zhang⁶, Yunfei Xu^1,3,*, Yifan Chen^1,2,3,*, Yang Yan^1,2,3,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.072373 - 23 March 2026

Abstract Objectives: Bladder cancer (BCa) progression is closely linked to the immune microenvironment. However, the key molecules that regulate this microenvironment and their specific mechanisms remain poorly understood. This study aims to identify a key molecule and elucidate its mechanisms, providing a theoretical basis for identifying novel therapeutic targets. Methods: Immune microenvironment-related genes in BCa were identified using The Cancer Genome Atlas and Shanghai Tenth People’s Hospital datasets. Proteasome 26S subunit non-ATPase 2 (PSMD2) expression was validated via quantitative polymerase chain reaction (qPCR), Western blot (WB) analysis, and immunofluorescence (IF). In vitro and in vivo experiments confirmed the… More > Graphic Abstract

Maolei Cui^1,2,*, Zengmin Lun^1,2, Jie Zhang^1,2, Jun Niu^1,2, Pufu Xiao^1,2

FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.2, 2026, DOI:10.32604/fdmp.2026.075360 - 04 March 2026

Abstract To clarify fluid flow mechanisms and establish effective development conditions in continental shale oil reservoirs, a high-temperature, high-pressure steady-state flow system integrated with nuclear magnetic resonance (NMR) technology has been developed. The apparatus combines sample evacuation, rapid pressurization and saturation, and controlled displacement, enabling systematic investigation of single-phase shale oil flow under representative reservoir conditions. Related experiments allow proper quantification of the activation thresholds and relative contributions of different pore types to flow. A movable fluid index (MFI), defined using dual T₂ cutoff values, is introduced accordingly and linked to key flow parameters. The results reveal… More > Graphic Abstract

Abdo Hasan AL-Qadri^1,*, Mohammed Ateik Al-Khadher², Nadia Saraa³, Ahmed Abdalmonem Mohmed Ahmed⁴, Pengfei Chen¹, Salaheldin Farah Bakhiet⁵, Ismael Salamah Albursan², Hazim M. Alhaqbani⁶, Abdullah Saad Almutairi⁷

Journal of Psychology in Africa, Vol.36, No.1, pp. 65-77, 2026, DOI:10.32604/jpa.2025.069675 - 26 February 2026

Abstract Burnout is an escalating global occupational health challenge, requiring valid and reliable assessment tools. This study validates the Copenhagen Burnout Inventory (CBI) for assessing burnout among Sudanese workers in the education, healthcare, and banking sectors, where burnout prevalence is high. Utilizing the 19-item CBI, translated into Arabic, the study measured burnout across three dimensions: Personal Burnout (PB), Work-related Burnout (WB), and Client-related Burnout (CB). A total of 1068 participants were surveyed, including 438 teachers (41%), 326 healthcare workers (30.5%), and 304 bank employees (28.5%). Exploratory and Confirmatory Factor Analyses confirmed the construct validity of the… More >

Shaoyu Hu¹, Bingquan Li¹, Jianfeng Ouyang¹, Yue Meng², Jian Ji³, Xiaofei Zheng^4,*, Yongheng Ye^1,*

BIOCELL, Vol.50, No.2, 2026, DOI:10.32604/biocell.2026.071651 - 14 February 2026

Abstract Objectives: Dysregulated osteoclast function contributes to skeletal diseases. However, the specific ubiquitination regulators of the osteoclastogenesis repressor MafB, particularly at the post-translational level, remain undefined. This study aims to identify ubiquitin-specific proteases (USPs) that deubiquitinate MafB and enhance its stability. Methods: We constructed a MafB-conjugated luciferase and overexpressed 40 individual USPs, measuring changes in luciferase activity. The identified USP was overexpressed in human CD14⁺ peripheral blood mononuclear cells (PBMCs) to evaluate its effect. Osteoclast differentiation was assessed through osteoclast marker Integrin alpha-V (CD51) staining and Western blot analysis. Co-immunoprecipitation (co-IP) was performed to assess the interplay.… More >

Alaa Tolah^*

CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.074997 - 10 February 2026

Abstract The rapidly evolving cybersecurity threat landscape exposes a critical flaw in traditional educational programs where static curricula cannot adapt swiftly to novel attack vectors. This creates a significant gap between theoretical knowledge and the practical defensive capabilities needed in the field. To address this, we propose TeachSecure-CTI, a novel framework for adaptive cybersecurity curriculum generation that integrates real-time Cyber Threat Intelligence (CTI) with AI-driven personalization. Our framework employs a layered architecture featuring a CTI ingestion and clustering module, natural language processing for semantic concept extraction, and a reinforcement learning agent for adaptive content sequencing. By… More >

Noor Mueen Mohammed Ali Hayder^1,2, Seyed Amin Hosseini Seno^2,*, Hamid Noori², Davood Zabihzadeh³, Mehdi Ebady Manaa^4,5

CMC-Computers, Materials & Continua, Vol.87, No.1, 2026, DOI:10.32604/cmc.2025.073236 - 10 February 2026

Abstract Distributed Denial of Service (DDoS) attacks are one of the severe threats to network infrastructure, sometimes bypassing traditional diagnosis algorithms because of their evolving complexity. Present Machine Learning (ML) techniques for DDoS attack diagnosis normally apply network traffic statistical features such as packet sizes and inter-arrival times. However, such techniques sometimes fail to capture complicated relations among various traffic flows. In this paper, we present a new multi-scale ensemble strategy given the Graph Neural Networks (GNNs) for improving DDoS detection. Our technique divides traffic into macro- and micro-level elements, letting various GNN models to get… More >

Huaruo Chen^1,2, Gefan Wang¹, Hancai Qiu¹, Hui Ma¹, Zhentao Peng¹, Ruihan Liu³, Feng Xu^4,*

International Journal of Mental Health Promotion, Vol.28, No.1, 2026, DOI:10.32604/ijmhp.2025.073911 - 28 January 2026

Abstract Background: As an important indicator of subjective well-being (SWB), decent work is a key guarantee for the sustainable development of teachers and their psychological health and work quality. Faced with the rapid development of artificial intelligence and the global labor market, vocational college teachers are facing challenges such as workload pressure and limited career development, which may harm their well-being. This study aims to localize the measurement method of decent work in Chinese vocational education based on the theory of the Psychology of Working Theory, and explore the relationship mechanism between organizational support, career adaptability, decent… More >

Myunghoon Roh¹, Katalin Parti², Diego Gomez-Baya^3,*, Cheryl E. Sanders⁴, Elizabeth K. Englander⁵

International Journal of Mental Health Promotion, Vol.28, No.1, 2026, DOI:10.32604/ijmhp.2025.072605 - 28 January 2026

Abstract Background: Bullying is a current social and educational problem with detrimental consequences in adolescence and later life stages. Previous research has explored the risk or protective factor at different socio-ecological levels, but further integration is needed to examine the relationships of family characteristics. This study examines how parenting style and attachment relate to adolescents’ bullying and cyberbullying, and whether parental phubbing mediates these links. Methods: Grounded in social bonding theory, we surveyed a cross-sectional convenience sample of U.S. college students (N = 545; Mean_age = 19.60, SD = 1.41) who retrospectively reported middle/high-school experiences from Massachusetts, Colorado,… More >

Enrique Oropeza-Maetínez¹, Eva G. Palacios-Serrato¹, Marina Macías-Silva², Angeles C. Tecalco-Cruz^1,*

European Cytokine Network, Vol.36, No.3, pp. 38-51, 2025, DOI:10.1684/ecn.2025.0503 - 28 February 2026

Abstract Background: Glioblastoma is a lethal primary brain tumor that is therapeutically challenging due to its rapid progression. Interferon-gamma (IFN-γ) signaling is altered in glioblastoma. Moreover, proteolytic enzymes, known as proteases, have been linked to the invasive growth of cancerous cells. In this study, we aimed to identify a glioblastoma-associated protease group and to determine its potential connection with IFN-γ signaling. Methods: Using cancer expression databases, we analyzed the differential expression of 35 proteases in glioblastoma and healthy brain tissue, and the relevance of their deregulation to patient survival. We also explored correlations between IFN-γ signaling… More >