Nugroho Agung Pambudi^1,2,4,*, Andrew Chapman, Alfan Sarifudin^1,3, Desita Kamila Ulfa⁴, Iksan Riva Nanda⁵

Energy Engineering, Vol.121, No.5, pp. 1143-1159, 2024, DOI:10.32604/ee.2024.047555

Abstract One of the impacts of the Fukushima disaster was the shutdown of all nuclear power plants in Japan, reaching zero production in 2015. In response, the country started importing more fossil energy including coal, oil, and natural gas to fill the energy gap. However, this led to a significant increase in carbon emissions, hindering the efforts to reduce its carbon footprint. In the current situation, Japan is actively working to balance its energy requirements with environmental considerations, including the utilization of hydrogen fuel. Therefore, this paper aims to explore the feasibility and implications of using hydrogen power plants as a… More >

Yan Dong^1,2, Kang Zhao¹, Liang Gao¹, Hao Li^1,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1-18, 2024, DOI:10.32604/cmc.2024.048870

Abstract With the continuous advancement in topology optimization and additive manufacturing (AM) technology, the capability to fabricate functionally graded materials and intricate cellular structures with spatially varying microstructures has grown significantly. However, a critical challenge is encountered in the design of these structures–the absence of robust interface connections between adjacent microstructures, potentially resulting in diminished efficiency or macroscopic failure. A Hybrid Level Set Method (HLSM) is proposed, specifically designed to enhance connectivity among non-uniform microstructures, contributing to the design of functionally graded cellular structures. The HLSM introduces a pioneering algorithm for effectively blending heterogeneous microstructure interfaces. Initially, an interpolation algorithm is… More >

Maria Gul¹, Imran Ali Khan¹, Gohar Zaman², Atta Rahman^3,*, Jamaluddin Mir², Sardar Asad Ali Biabani^4,5, May Issa Aldossary⁶, Mustafa Youldash⁷, Ashraf Saadeldeen⁸, Maqsood Mahmud⁹, Asiya Abdus Salam⁶, Dania Alkhulaifi³, Abdullah AlTurkey³

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1631-1657, 2024, DOI:10.32604/cmc.2024.048289

Abstract Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, many researchers proposed game theoretic models to avoid and remove obstacles for crowd evacuation. Game theoretical models aim to study and analyze the strategic behaviors of individuals within a crowd and their interactions during the evacuation. Game theoretical models have some limitations in the context of crowd evacuation. These models consider a group of individuals as homogeneous objects with the same goals, involve complex mathematical formulation, and cannot model real-world scenarios such as panic, environmental information, crowds that move dynamically, etc. The proposed work presents… More >

DIBYENDU S. BAG^*, SHILPI TIWARI, AKANSHA DIXIT, KM. MEENU

Journal of Polymer Materials, Vol.40, No.1-2, pp. 105-123, 2023, DOI:10.32381/JPM.2023.40.1-2.9

Abstract In this paper, we report the microstructural investigation and influence of H-bonding on the thermal behavior e.g., glass transition (T_g ) and thermal degradation of chiral copolymers of (R)- N-(1-phenyl-ethyl) methacrylamide (R-NPEMAM) and 2-hydroxy ethyl methacrylate (HEMA). The T_g increases with the increase of chiral unit content in the copolymers and then attains optimum at around 25 mole % of chiral content. Thereafter it decreases with the increase of chiral content. The effect of copolymer composition and secondary interaction associated with the Hbonding on the thermal properties of these copolymers was also studied. Secondary interaction, specifically H-bonding has been interpreted… More >

Molly Clarke^1,*, Karin Hamann², Nancy Klein², Laura Olivieri³, Yue-Hin Loke²

Congenital Heart Disease, Vol.19, No.1, pp. 5-17, 2024, DOI:10.32604/chd.2024.046328

Abstract Background: Patients with congenital heart disease (CHD) will transition to lifelong adult congenital cardiac care. However, their structural heart disease is challenging to convey via two-dimensional drawings. This study utilized a tele-educational environment, with personalized three-dimensional (3D) modeling and health Details (3D + Details = “4D”), to improve actual and perceived knowledge, both important components of transition readiness in CHD patients. Methods: Participants aged ≥13 years with a history of CHD and cardiac magnetic resonance imaging (MRI) studies were eligible. Cardiac MRI datasets were then used to segment and create 3D heart models (using Mimics, Materialize Inc.). Participants first completed… More >

REZA YADOLLAHVANDMIANDOAB^1,#, MEHRSA JALALIZADEH^1,#, FRANCIELE APARECIDA VECHIA DIONATO¹, KEINI BUOSI¹, PATRÍCIA A. F. LEME¹, LUCIANA S. B. DAL COL¹, CRISTIANE F. GIACOMELLI¹, ALEX DIAS ASSIS¹, NASIM BASHIRICHELKASARI¹, LEONARDO OLIVEIRA REIS^1,2,*

Oncology Research, Vol.32, No.4, pp. 597-605, 2024, DOI:10.32604/or.2024.045442

Abstract Bladder cancer (BC) is the 10th most common cancer worldwide, with about 0.5 million reported new cases and about 0.2 million deaths per year. In this scoping review, we summarize the current evidence regarding the clinical implications of single-cell sequencing for bladder cancer based on PRISMA guidelines. We searched PubMed, CENTRAL, Embase, and supplemented with manual searches through the Scopus, and Web of Science for published studies until February 2023. We included original studies that used at least one single-cell technology to study bladder cancer. Forty-one publications were included in the review. Twenty-nine studies showed that this technology can identify… More > Graphic Abstract

HYUNG SUN KIM^1,#, YUN SUN LEE^2,#, SEUNG MYUNG DONG³, HYO JUNG KIM¹, DA EUN LEE², HYEON WOONG KANG², MYEONG JIN KIM², JOON SEONG PARK^1,*

Oncology Research, Vol.32, No.4, pp. 615-624, 2024, DOI:10.32604/or.2024.044029

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid malignancies. A specific mechanism of its metastasis has not been established. In this study, we investigated whether Neural Wiskott-Aldrich syndrome protein (N-WASP) plays a role in distant metastasis of PDAC. We found that N-WASP is markedly expressed in clinical patients with PDAC. Clinical analysis showed a notably more distant metastatic pattern in the N-WASP-high group compared to the N-WASP-low group. N-WASP was noted to be a novel mediator of epithelial-mesenchymal transition (EMT) via gene expression profile studies. Knockdown of N-WASP in pancreatic cancer cells significantly inhibited cell invasion, migration,… More > Graphic Abstract

Diego Angeli^a,*, Arturo Pagano^b, Mauro A. Corticelli^a, Alberto Fichera^b, Giovanni S. Barozzi^a

Frontiers in Heat and Mass Transfer, Vol.2, No.2, pp. 1-9, 2011, DOI:10.5098/hmt.v2.2.3003

Abstract A numerical analysis of transitional natural convection from a confined thermal source is presented. The system considered is an air-filled, square-sectioned 2D enclosure containing a horizontal heated cylinder. The resulting flow is investigated with respect to the variation of the Rayleigh number, for three values of the aspect ratio A. The first bifurcation of the low-Ra fixed-point solution is tracked for each A-value. Chaotic flow features are detailed for the case A = 2.5. The supercritical behaviour of the system is investigated using nonlinear analysis tools and phase-space representations, and the effect of the flow on heat transfer is discussed. More >

Patrick H. Oosthuizen^*

Frontiers in Heat and Mass Transfer, Vol.2, No.1, pp. 1-8, 2011, DOI:10.5098/hmt.v2.1.3004

Abstract The convective heat transfer to a window below which is mounted a natural convective heater has been numerically studied. The flow has been assumed to be three-dimensional and steady and to involve regions of laminar and turbulent flow. Fluid properties have been assumed constant except for the density change with temperature which leads to the buoyancy forces. The solution has been obtained using a commercial cfd code. Results have been obtained for a Prandtl number of 0.7. The effects of changes in the flow variables on the window Nusselt number and on the flow and temperature distributions have been examined. More >

JIYU WANG^1,#, LIUYING YI^2,#, KEKE HUANG¹, YANGYANG WANG¹, HUIPING WANG¹, ZHIMIN ZHAI^1,*

BIOCELL, Vol.48, No.3, pp. 453-462, 2024, DOI:10.32604/biocell.2024.047871

Abstract Background: The primary cause of treatment failure in patients with refractory or relapsed B-cell non-Hodgkin lymphoma (r/r B-NHL) is resistance to current therapies, and therapy-induced senescence (TIS) stands out as a crucial mechanism contributing to tumor drug resistance. Here, we analyzed SENEX/Rho GTPase Activating Protein 18 (ARHGAP18) expression and prognostic significance in doxorubicin-induced B-NHL-TIS model and r/r B-NHL patients, investigating its target in B-NHL cell senescence and the effect of combining specific inhibitors on apoptosis resistance in B-NHL-TIS cells. Methods: Raji cells were transfected with the human SENEX shRNA recombinant lentiviral vector (Sh-SENEX) and the empty vector negative (NC) to… More >