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  • Open Access

    EDITORIAL

    Hot Topics of Molecular and Cellular Biomechanics in 2022

    Guixue Wang1,2,*

    Molecular & Cellular Biomechanics, Vol.20, No.2, pp. 63-66, 2023, DOI:10.32604/mcb.2023.044564

    Abstract The analysis of biomechanical characteristics plays an important role in mastering the technical characteristics of athletes, providing guidance for the formulation and prevention of sports injury training plans and providing theoretical support for research on injury prevention and stability control in the sports field. With the importance of data analysis, the application scope of artificial intelligence methods is more extensive. For example, intelligent training systems can be used for athletes’ personalized and professional training, real-time monitoring and feedback of training data, and further reduce the risk of sports injury. However, deep learning methods process a large number of medical images… More >

  • Open Access

    REVIEW

    Reconstruction of the Hindlimb Locomotion of Confuciusornis (Aves) and Its Implication for the Origin of Avian Flight

    Xinsen Wei1, Ying Guo1,2,*, Yan Zhao1

    Molecular & Cellular Biomechanics, Vol.20, No.2, pp. 49-61, 2023, DOI:10.32604/mcb.2023.041173

    Abstract As one of the most basal avian clades, the Confuciusornithids are ideal in revealing the early evolution of avian flight. Birds’ hindlimbs are functionally diverse and contain a wealth of information about their behavior. The hindlimb of Confuciusornis, however, has only been studied in detail in terms of functional morphology, and quantitative studies that directly assess locomotor ability are relatively lacking. This has led to certain controversies on the behavior of Confuciusornis. This paper reviews the debates over the life habits and take-off ability of Confuciusornis, which are closely related to their hindlimb function. Several methodologies adopted engineering techniques, including… More >

  • Open Access

    ARTICLE

    Computational Fluid Dynamics Analysis of Upper Airway Changes after Protraction Headgear and Rapid Maxillary Expansion Treatment

    Haoran Xu1, Shuai Chen2,*, Xue Song1,3, Jingying Wang1,*

    Molecular & Cellular Biomechanics, Vol.20, No.1, pp. 15-22, 2023, DOI:10.32604/mcb.2023.029107

    Abstract Clinically, it is common for Class III patients with maxillary skeletal deficiency, which may result in a variety of adverse consequences. Protraction headgear and rapid maxillary expansion (PE) is an effective treatment, but its effect on upper airway hydrodynamics has not been reported. The main purpose of this study was to evaluate the changes of the flow in the upper airway after PE by computational fluid dynamics (CFD). The sample includes fifteen patients (6 males, 9 females, age 11.00 ± 1.00) and the paired T-test was used to analyze the differences between the measured data before and after treatment. The… More > Graphic Abstract

    Computational Fluid Dynamics Analysis of Upper Airway Changes after Protraction Headgear and Rapid Maxillary Expansion Treatment

  • Open Access

    ARTICLE

    Anatomical Feature Segmentation of Femur Point Cloud Based on Medical Semantics

    Xiaozhong Chen*

    Molecular & Cellular Biomechanics, Vol.20, No.1, pp. 1-14, 2023, DOI:10.32604/mcb.2022.026964

    Abstract Feature segmentation is an essential phase for geometric modeling and shape processing in anatomical study of human skeleton and clinical digital treatment of orthopedics. Due to various degrees of freedom of bone surface, the existing segmentation algorithms can hardly meet specific medical need. To address this, a novel segmentation methodology for anatomical features of femur model based on medical semantics is put forward. First, anatomical reference objects (ARO) are created to represent typical characteristics of femur anatomy by 3D point fitting in combination with medical priori knowledge. Then, local point clouds between adjacent anatomies are selected according to the AROs… More >

  • Open Access

    ARTICLE

    Effect of a Double Helical Spring Decompression Structure Backpack on the Lumbar Spine Biomechanics of School-Age Children: A Finite Element Study

    Fengping Li1, Dong Sun1,*, Qiaolin Zhang1,2,3, Hairong Chen1,2,3, István Bíró2,3, Zhiyi Zheng4, Yaodong Gu1,*

    Molecular & Cellular Biomechanics, Vol.20, No.1, pp. 35-47, 2023, DOI:10.32604/mcb.2023.041016

    Abstract Background: A children’s backpack is one of the important school supplies for school-age children. Long-term excessive weight can cause spinal deformity that cannot be reversed. This study compared a double helical spring decompression structure backpack (DHSB) with a traditional backpack (TB) to explore the optimization of decompression devices on upper body pressure. The finite element (FE) method was then used to explore the simulation of lumbar stress with different backpacks, in order to prove that DHSB can reduce the influence of backpack weight on lumbar vertebrae, avoid the occurrence of muscle discomfort and spinal deformity in children; Methods: 18 male… More > Graphic Abstract

    Effect of a Double Helical Spring Decompression Structure Backpack on the Lumbar Spine Biomechanics of School-Age Children: A Finite Element Study

  • Open Access

    ARTICLE

    Reliability of Foot Intrinsic Muscle Strength Testing and Correlation with Corresponding Muscle Morphology in Elderly Adults

    Lulu Yin1,#, Kun Dong1,#, Zhangqi Lai2, Lin Wang1,*

    Molecular & Cellular Biomechanics, Vol.20, No.1, pp. 23-33, 2023, DOI:10.32604/mcb.2023.040788

    Abstract Age-related loss of foot intrinsic muscle (FIM) strength may be associated with disability, falls, and inability to perform daily activities. Previous studies have determined the reliability of FIM strength testing and evaluated the relationship between FIM strength and corresponding muscle morphology in young adults. However, few studies have measured FIM strength in the older. Therefore, this study aimed to assess the intra- and inter-reliability of FIM strength tests and the relationship between FIM strength and FIM size in the older. A total of 61 participants aged 60–75 years were recruited, and 18 of them were selected randomly for the verification… More > Graphic Abstract

    Reliability of Foot Intrinsic Muscle Strength Testing and Correlation with Corresponding Muscle Morphology in Elderly Adults

  • Open Access

    ARTICLE

    Lower Limb Muscle Forces in Table Tennis Footwork during Topspin Forehand Stroke Based on the OpenSim Musculoskeletal Model: A Pilot Study

    Yuqi He1,2,3, Shirui Shao1, Gusztáv Fekete3, Xiaoyi Yang1, Xuanzhen Cen1,4, Yang Song1,4, Dong Sun1,*, Yaodong Gu1,*

    Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 221-235, 2022, DOI:10.32604/mcb.2022.027285

    Abstract Introduction: Footwork is one of the training contents that table tennis players and coaches focus on. This study aimed to gain a thorough understanding of the muscle activity of the table tennis footwork and creating a musculoskeletal model to investigate the muscle forces, joint kinematic, and joint kinetic characteristics of the footwork during topspin forehand stroke. Methods: Six male table tennis athletes (height: 171.98 ± 4.97 cm; weight: 68.77 ± 7.86 kg; experience: 10.67 ± 1.86 years; age: 22.50 ± 1.64 years) performed chasse step and one-step footwork to return the ball from the coach by topspin forehand stroke. The… More >

  • Open Access

    REVIEW

    Current Perspectives on Umbilical Cord Abnormalities Including Blood Flow Parameters Based on Ultrasound Observations

    Xue Song1,2, Cun Liu2, Jingying Wang1,*, Xinglian Yang1, Mingrui Li1

    Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 209-219, 2022, DOI:10.32604/mcb.2022.026082

    Abstract The umbilical cord is a vital structure between the fetus and placenta for the growth and well-being of the fetus. Although the umbilical cord may be the only organ that dies at the beginning of life, it is one of the most important parts of the feta-placental unit and plays a role in determining how life begins. In general, the prenatal examination of the umbilical cord is limited to the observation of the number of vessels and the evaluation of umbilical artery blood flow parameters. Pathologists have done more research on the morphological characteristics of the umbilical cord and linked… More >

  • Open Access

    ARTICLE

    Insilico Anticancer Peptide Prediction from Curcuma longa

    Sunil Kumar Suryawanshi1, Usha Chouhan2, Jyoti Kant Choudhari2,*

    Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 191-208, 2022, DOI:10.32604/mcb.2022.023911

    Abstract Cancer is the second biggest cause of death globally, and the use of therapeutic peptides to specifically target and destroy cancer cells has gotten much interest. Cancer peptides or vaccinations are utilized to treat cancer nowadays, apart from chemotherapy, which has significant discomfort, side effects and costly. It is time demanding to identify and predict potential anticancer peptides using computational biology approaches. Thus, 3-D molecular modeling is being used to find possible ACP candidates. In this research, Curcuma longa has predicted peptide sequences were docked on breast cancer receptors and used a molecular docking technique to assess the anticipated peptides’… More >

  • Open Access

    ARTICLE

    The Effect of Specialized Digital Training on Double Poling Technique for Para Seated Cross-Country Skiing Athletes

    Yong Wang1, Dong Sun1,*, Anand Thirupathi1, Julien S. Baker2, Yaodong Gu1,*

    Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 177-189, 2022, DOI:10.32604/mcb.2022.021764

    Abstract Purpose: In order to satisfy the requirements of Chinese Para seated cross-country skiers special training for Double poling scientifically, and the individualized strength training of Paralympic athletes, this study aims to explore the effect of the full-dimensional servo-driven intelligent training system on para cross-country skiers’ strength training. Methods: 12 Para seated cross-country skiing athletes were included (6 males and 6 females: LW10.5-LW12), 4 weeks of training of the Double poling based on the centripetal isotonic mode of the full-dimensional servo-driven intelligent training system, the special strength quality indicators include the speed and power of the Double poling in the centripetal… More >

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