Sunil Kumar Suryawanshi¹, Usha Chouhan², Jyoti Kant Choudhari^2,*

Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 191-208, 2022, DOI:10.32604/mcb.2022.023911

Abstract Cancer is the second biggest cause of death globally, and the use of therapeutic peptides to specifically target and destroy cancer cells has gotten much interest. Cancer peptides or vaccinations are utilized to treat cancer nowadays, apart from chemotherapy, which has significant discomfort, side effects and costly. It is time demanding to identify and predict potential anticancer peptides using computational biology approaches. Thus, 3-D molecular modeling is being used to find possible ACP candidates. In this research, Curcuma longa has predicted peptide sequences were docked on breast cancer receptors and used a molecular docking technique to assess the anticipated peptides’… More >

Yong Wang¹, Dong Sun^1,*, Anand Thirupathi¹, Julien S. Baker², Yaodong Gu^1,*

Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 177-189, 2022, DOI:10.32604/mcb.2022.021764

Abstract Purpose: In order to satisfy the requirements of Chinese Para seated cross-country skiers special training for Double poling scientifically, and the individualized strength training of Paralympic athletes, this study aims to explore the effect of the full-dimensional servo-driven intelligent training system on para cross-country skiers’ strength training. Methods: 12 Para seated cross-country skiing athletes were included (6 males and 6 females: LW10.5-LW12), 4 weeks of training of the Double poling based on the centripetal isotonic mode of the full-dimensional servo-driven intelligent training system, the special strength quality indicators include the speed and power of the Double poling in the centripetal… More >

Suraj Shembekar^*, Dhananjay Zodpe, Pramod Padole

Molecular & Cellular Biomechanics, Vol.19, No.4, pp. 165-175, 2022, DOI:10.32604/mcb.2022.021513

Abstract Arteriovenous fistula (AVF) is the endorsed method of vascular access for hemodialysis in end-stage renal disease (ESRD). However, more than 60% of AVF fail to mature for hemodialysis. Intimal hyperplasia leads to stenosis is the primary cause of fistula failure. Wall shear stress (WSS) is one of the important parameters that enact a crucial role in building of intimal hyperplasia. The prime purpose of this research work is to investigate the effect of anastomosis angle on WSS, pressure drop, venous outflow rate and identify the optimal angle of anastomosis of AVF, so that it helps to standardize the surgical technique.… More >

Fengfeng Li¹, Huiyu Zhou^1,2, Datao Xu¹, Julien S. Baker³, Yaodong Gu^1,*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 115-129, 2022, DOI:10.32604/mcb.2022.022658

Abstract Research on dance lower extremity joint motion has been limited. Thus, the purpose of this study was to investigate the lower limb biomechanics differences between the side chasse step (SCS) and the bounce step (BS) of the second landing phase in Jive. Thirteen female recreational Latin dancers (Age: 22 ± 2.5 years; Height: 1.65 ± 0.05 m; Weight: 50 ± 4.5 kg; Dance experience: 4 ± 2 years) were involved in the experiment. The same music was used throughout the data collection period. We intended to determine whether these two steps generate different kinematic and kinetic data. The ankle, hip, and knee joint angle, moment, velocity, and… More >

Yixin Liu^*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 131-139, 2022, DOI:10.32604/mcb.2022.019342

Abstract When basketball players play against each other in a game, better coordinated balance can give them a better advantage. This paper briefly introduces the coordination balance and core strength of basketball players. Twenty basketball varsity members were selected from Chengdu College of University of Electronic Science and Technology of China as subjects for the test. The athletes were randomly divided into a control group and an experimental group. The control group received regular strength training, and the experimental group received core strength training in addition to regular training. Both groups underwent isometric muscle strength test, coordination and balance test and… More >

Hongfang Song^1,2, Aike Qiao^3,4,*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 159-164, 2022, DOI:10.32604/mcb.2022.019005

Abstract Putting the thread through the eye of a needle is a very ordinary issues in daily life. The mechanism of putting the thread through the eye of a needle is quite similar to threading a series of polymer chains through synthetic macrocycle in bioscience. A new rubbing approach to thread through the eye of a needle was proposed in this paper, and its potential application in the fields of biomechanics and mechanobiology to mimic the micro scale assembly processes was discussed. More >

Jia Qin^1,2,3,4,5, Lin An^1,2,3,4,5,*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 151-157, 2022, DOI:10.32604/mcb.2022.018578

Abstract Myopia is a common ophthalmic deficiency. The structure and function of choroid layer is assumed to be associated with myopia. In this study, a laboratory developed spectral domain optical coherence tomography scanning system is used to image human eyes. The axial resolution of the system is about 7 μm, and the acquisition rate is 100 kHz. Firstly, a cross-sectional image was acquired by averaging 100 images from imaging posterior segment of each eye. The choroid thickness was measured by 11 discrete points. The average thickness of normal human eyes was (0.296 ± 0.126) mm, whereas the average choroid thickness of… More >

Enhua Li^*

Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 141-149, 2022, DOI:10.32604/mcb.2022.018558

Abstract This study aims to analyze the difference in biomechanical properties of football players at different levels when kicking the football with the inner edge of the instep. Before the experiment, ten football players were selected; five were higher than the national level (group A), and the other five players were lower than the national level II (group B). During the experiment, the motion process was captured by a high-speed camera for biomechanical analysis. It was found that in group A, the thigh and leg swung in less time and larger amplitude, the acceleration of backswing and forward swing of the… More >

Jingying Lu¹, Datao Xu¹, Wenjing Quan^1,2, Julien S. Baker³, Yaodong Gu^1,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 61-75, 2022, DOI:10.32604/mcb.2022.019978

Abstract Objectives: Although overuse running injury risks for the ankle and knee are high, the effect of different shoe designs on Achilles tendon force (ATF) and Patellofemoral joint contact force (PTF) loading rates are unclear. Therefore, the primary objective of this study was to compare the ATF at the ankle and the PTF and Patellofemoral joint stress force (PP) at the knee using different running shoe designs (forefoot shoes vs. normal shoes). Methods: Fourteen healthy recreational male runners were recruited to run over a force plate under two shoe conditions (forefoot shoes vs. normal shoes). Sagittal plane ankle and knee kinematics… More >

Reza Samanipour¹, Aida Pourmostafa², Adel Marzban², Sara Tabatabaee³, Hasan Bahraminasab², Amir Ali Hamidieh⁴, Amirhossein Tavakoli^4,*

Molecular & Cellular Biomechanics, Vol.19, No.2, pp. 97-104, 2022, DOI:10.32604/mcb.2022.019080

Abstract Based on the remarkable demand for facial reconstitute or reshape fillers due to the dermal defects arising from specific diseases, trauma, or aging, several natural or synthetic materials have been investigated. Among the evaluated materials, decellularized dermis is one of the most biocompatible choices for the aim of skin tissue regenerative approaches. On the other hand, Carboxymethyl Cellulose (CMC), a synthetic polysaccharide, with the desirable degradability, biomechanical stability, and nontoxicity seems to be an acceptable reinforcement agent for decellularized dermis. Thus, in this research, an injectable soft tissue filler contained of human-derived decellularized collagen and CMC was fabricated. The cell-removal… More >