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  • Open Access

    REVIEW

    Understanding the role of miRNAs in the pathogenesis of brain arteriovenous malformations

    ILGIZ GAREEV1, OZAL BEYLERLI1, CHUNLEI WANG2,3, ANDREI SOKHATSKII2,3, YANCHAO LIANG2,3, HUAN XIANG2,3, CHUNYANG LIU2,3, XUN XU2,3, YANG GUANG2,3

    BIOCELL, Vol.46, No.1, pp. 27-35, 2022, DOI:10.32604/biocell.2022.016288

    Abstract Brain arteriovenous malformations (AVMs) are abnormal vessels that are prone to rupture, causing life-threatening intracerebral hemorrhage (ICH). Understanding the molecular basis of pathogenesis, timely diagnosis, and treatment of brain AVMs are some of the urgent problems in neurosurgery. MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNAs are involved in almost all biological processes, including cell proliferation, apoptosis, and cell differentiation. Recent studies have shown that miRNAs can be involved in brain AVMs formation and rupture. There are also extracellular forms of miRNAs. Circulating miRNAs have been detected in the blood circulation and other body fluids. Owing to… More >

  • Open Access

    ARTICLE

    Antimicrobial activities of three seaweeds extract against some human viral and bacterial pathogens

    JELAN MOFEED1,2, MOHAMED DEYAB3, ABDELNASER MOHAMED3, MAHMOUD MOUSTAFA4,5, SALLY NEGM6,7, EMAD EL-BILAWY1

    BIOCELL, Vol.46, No.1, pp. 247-261, 2022, DOI:10.32604/biocell.2022.015966

    Abstract

    Microbial infections cause complicated health influences along with bad economic impacts. In the present investigation, three dominant seaweeds namely, Amphiroa anceps, Corallina officinalis and Sargassum filipendula were collected from different Egyptian sites at the Red Sea and Mediterranean Sea during autumn 2019. Organic extracts of the three algae were screened for their antibacterial activity against three pathogenic bacteria Salmonella typhiimurium, Staphylococcus aureus and Escherichia coli, in addition to in vitro antiviral activity against Rotavirus (RV), and Coxsackie virus B3 (CVB3) that cause severe diseases in human. Organic extract of A. anceps, C. officinalis and S. filipendula inhibit E. coli cells… More >

  • Open Access

    ARTICLE

    Forkhead box protein O1 (FoxO1) regulates lipids metabolism and cell proliferation mediated by insulin and PI3K-Akt-mTOR pathway in goose primary hepatocytes

    RONGXUE WEI1, CHUNCHUN HAN1,*, FENGJIANG YE1, SHOUHAI WEI2, FANG HE1, HEHE LIU1, LIANG LI1, HONGYONG XU1, SHENQIANG HU1, XIANYIN ZENG2

    BIOCELL, Vol.46, No.1, pp. 171-183, 2022, DOI:10.32604/biocell.2022.015409

    Abstract In order to explore the role of forkhead box protein O1 (FoxO1) in the lipid metabolism and cell proliferation, goose primary hepatocytes were isolated and incubated with insulin or PI3K-Akt-mTOR pathway dual inhibitor NVP-BEZ235, and then transfected with FoxO1 interference plasmid. The related parameters of lipid metabolism and cell proliferation were measured. The results firstly showed that FoxO1 interference increased the intracellular TG and lipids concentration (P < 0.05); and increased the proliferative index (PI), cell DNA synthesis, protein expression of Cyclin D1 in goose primary hepatocytes (P < 0.05). Secondly, the co-treatment of insulin and FoxO1 interference increased the… More >

  • Open Access

    ARTICLE

    The neuroprotection of electro-acupuncture via the PGC-1α/TFAM pathway in transient focal cerebral ischemia rats

    LUPING YANG1,#, YIJING JIANG2,#, XIAOQIAN YE3,#, YONGMEI YOU2, LING LIN2, JING LIAN2, JUAN LI1, SHANLI YANG2, XIEHUA XUE2

    BIOCELL, Vol.46, No.1, pp. 235-245, 2022, DOI:10.32604/biocell.2022.014997

    Abstract ATP depletion is one of the pathological bases in cerebral ischemia. Electro-acupuncture (EA) is widely used in clinical practice for ischemia. However, the mechanism of EA remains unclear. The purpose of this study was to investigate whether EA could activate the AMPK/PGC-1α/TFAM signaling pathway and, consequently, increase the preservation of ATP in rats with ischemia. In this study, 48 rats were randomly divided into four groups as a sham-operation control group (sham group), a middle cerebral artery occlusion group (MCAO group), an EA group, and an EA group blocked by the AMPK inhibitor compound C (EA + CC group) (N… More >

  • Open Access

    ARTICLE

    Green Method, Optical and Structural Characterization of ZnO Nanoparticles Synthesized Using Leaves Extract of M. oleifera

    José Vulfrano González-Fernández1,*, Diego David Pinzón-Moreno1, Antony Alexander Neciosup-Puican2, María Verónica Carranza-Oropeza1

    Journal of Renewable Materials, Vol.10, No.3, pp. 833-847, 2022, DOI:10.32604/jrm.2021.017377

    Abstract ZnO nanoparticles (ZnO-NP) present innovative optical, electrical, and magnetic properties that depend on specific characteristics, e.g., size, distribution, and morphology. Thus, these properties are essential to address various applications in areas such as electronics, medicine, energy, and others. In addition, the performance of this ZnONP depends of their preparation which can be done by chemical, physical, and biological methods. Meanwhile, nowadays, the main interest in developing ZnO-NP synthesis through biological methods bases on the decrease of use of toxic chemicals or energy applied to the procedures, making the process more cost-effective and environmentally friendly. However, the large-scale production of nanoparticles… More >

  • Open Access

    REVIEW

    Properties and Applications of Bamboo Fiber–A Current-State-of-the Art

    Chen Chen1,2, Haitao Li1,2,*, Assima Dauletbek1,2, Feng Shen3, David Hui4, Milan Gaff5, Rodolfo Lorenzo6, Ileana Corbi7, Ottavia Corbi7, Mahmud Ashraf8

    Journal of Renewable Materials, Vol.10, No.3, pp. 605-624, 2022, DOI:10.32604/jrm.2022.018685

    Abstract Fibers are used in many forms in engineering applications–one of the most common being used as reinforcement. Due to its renewable short natural growth cycle and abundance of bamboo resources, bamboo fiber has attracted attention over other natural fibers. Bamboo fiber has a complex natural structure but offers excellent mechanical properties, which are utilized in the textile, papermaking, construction, and composites industry. However, bamboo fibers can easily absorb moisture and are prone to corrosion limiting their use in engineering applications. Therefore, a better understanding of bamboo fiber is particularly important. This paper reviews all existing research on the mechanical characterization… More >

  • Open Access

    REVIEW

    g-C3N4 Derived Materials for Photocatalytic Hydrogen Production: A Mini Review on Design Strategies

    Kai Su1,*, Shaoqi Deng1, Linxiao Li1, Qirui Qin1, Jingyu Yang1, Yan Chen2,3, Shengli Zhang1, Junming Chen1

    Journal of Renewable Materials, Vol.10, No.3, pp. 653-663, 2022, DOI:10.32604/jrm.2022.018556

    Abstract Hydrogen production through solar energy is one of the most important pathways to meet the growing demand of renewable energy, and photocatalyst participation in solar hydrolytic hydrogen production has received great attention in recent years in terms of low cost, high efficiency, and flexible design. Particularly, g-C3N4 (Graphitic-like carbon nitride material), as a unique material, can catalyze the hydrogen production process by completing the separation and transmission of charge. The easily adjustable pore structure/surface area, dimension, band-gap modulation and defect have shown great potential for hydrogen production from water cracking. In this review, the most recent advance of g-C3N4 including… More > Graphic Abstract

    g-C<sub>3</sub>N<sub>4</sub> Derived Materials for Photocatalytic Hydrogen Production: A Mini Review on Design Strategies

  • Open Access

    ARTICLE

    Analysis of Crack Expansion and Morphology of Cross-Laminated Timber Planar Shear Test

    Yujie Huang1, Yifan Zhang1, Zheng Wang1,*, Assima Dauletbe2, Yao Lu1, Zhaoyu Shen1

    Journal of Renewable Materials, Vol.10, No.3, pp. 849-870, 2022, DOI:10.32604/jrm.2022.018515

    Abstract To describe the dynamic cracking process of the CLT vertical layer, the correlation between a load-displacement curve, specimen cracking, and planar shear failure mechanism of the CLT were explored. A three-point bending test and an improved planar shear test are used to evaluate the shear performance of the CLT. In this study, the load-displacement curve is recorded, the experimental part is synchronized with the video, the dynamic process of cracking of the vertical layer is observed and analyzed throughout the test. From the load-displacement curve, the image characteristics of the initial cracking and the sudden increase of the cracking of… More > Graphic Abstract

    Analysis of Crack Expansion and Morphology of Cross-Laminated Timber Planar Shear Test

  • Open Access

    ARTICLE

    A Soy Protein-Based Composite Film with a Hierarchical Structure Inspired by Nacre

    Yecheng Xu1, Chaojie Xu1, Mingsong Chen1, Jianzhang Li1, Ling Zeng2, Jing Luo3, Qiang Gao1,*, Sheldon Q. Shi4,*

    Journal of Renewable Materials, Vol.10, No.3, pp. 639-652, 2022, DOI:10.32604/jrm.2022.018509

    Abstract Soy protein-based composite film is a potential replacement for petroleum-based film with multipurpose applications and cleaner production. It is difficult to improve both the tensile strength and toughness of a protein-based film without sacrificing its elongation. In this study, inspired by the hierarchical structure of nacre, a facile yet delicate strategy was developed to fabricate a novel bio-based film with excellent toughness and high strength. Triglycidylamine (TGA) crosslinked soy protein (SPI) as hard phase and thermoplastic polyurethane elastomer (TPU) as soft phase comprise an alternative lay-up hierarchical structure. The interface of these two phases is enhanced using triglycidylamine (TGA) surface-modified… More >

  • Open Access

    ARTICLE

    The Use of as Natural Coagulant in Algerian Drinking Water Treatment Plant

    Abderrezzaq Benalia1,2, Kerroum Derbal2,*, Amel Khalfaoui1, Antonio Pizzi3, Ghouti Medjahdi4

    Journal of Renewable Materials, Vol.10, No.3, pp. 625-637, 2022, DOI:10.32604/jrm.2022.017848

    Abstract The purpose of this work is the study the ability of the plant material Aloe vera to act as natural coagulant using raw water obtained from a drinking water treatment plant (Mila, Algeria). Different solvents such as: NaCl; NaOH and HCl were used as chemical activators to extract the active components from the Aloe vera plant, and different coagulation-flocculation experiments were conducted in a jar test apparatus to evaluate the performance of the extracted coagulant. Also, the effect of coagulant dose on some water parameters such as turbidity, pH, total alkalinity and organic matter were investigated. The results showed that… More > Graphic Abstract

    The Use of  as Natural Coagulant in Algerian Drinking Water Treatment Plant

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