Shlomi Barak¹, Netanel Waldenberg¹, Aharon Peretz², Reut Bartoov¹, Guy Bar¹, Snir Dekalo^3,*

Canadian Journal of Urology, DOI:10.32604/cju.2025.066936

Abstract Background: Hormonal treatment and response as a predictor of sperm retrieval prior to microdissection testicular sperm extraction (micro-TESE) are not well established in the current literature. This study aimed to investigate the hormonal response as a predictor of sperm retrieval among men with nonobstructive azoospermia (NOA). Methods: Seventy-seven consecutive patients who had testosterone levels ≤ 14 nmol/L were treated medically with an aromatase inhibitor or recombinant human chorionic gonadotropin (rec-hCG) prior to micro-TESE and were included. Thirty-four (44.2%) had unexplained NOA (UNEX), 25 (32.5%) had Klinefelter syndrome (KS), 8 (10.4%) had a history of cryptorchidism… More >

Wael A. Altabey^*

Structural Durability & Health Monitoring, DOI:10.32604/sdhm.2025.073949

Abstract The study of long-term pavement performance is a fundamental topic in the field of highway engineering. Through comprehensive and in-depth research on the pavement system, the previous scattered, one-sided, superficial, and perceptual knowledge and experience are summarized and sublimated into a systematic and complete engineering theory, thereby providing powerful guidance and assistance for the practice of pavement design, construction, maintenance, operation, and management. In this research, the mentoring system deployment technology for automatic monitoring is carried out for long-term pavement performance. By burying a variety of sensors in different parts of the road surface, base,… More >

Zhengyan Chang, Weiwei Wang, Mingliang Yang, Heng Yang, Qing Dong, Keyuan Zhao, Jie Yuwen^*

Structural Durability & Health Monitoring, DOI:10.32604/sdhm.2025.066572

Abstract To address the neglect of seismic performance in conventional double-girder bridge crane optimization, this paper introduces a time-history analysis-based seismic optimization methodology for crane structures. Using a 25-t nuclear power crane as a case study, a bridge frame finite element model is established and validated through static analysis, confirming its accurate representation of the physical entity’s mechanical behavior. Furthermore, with bridge mass reduction as the objective and structural strength, stiffness, stability, and seismic mechanical performance as constraints, an optimization model is developed employing the Whale Optimization Algorithm (WOA). More >

Renfei Chang¹, Liqiang Jin¹, Haihui Xie^2,*, Kai Zhang³, Musheng Ye⁴

Structural Durability & Health Monitoring, DOI:10.32604/sdhm.2025.063718

Abstract To investigate the impact of temporary structures on the mechanical behavior of shaped bridge towers during the construction process, the Dianbu River Special Bridge was selected as the engineering background. A finite element model of the middle tower column during the construction stage was established using ABAQUS to analyze the effects of key parameters, including the angle and pretension of temporary cables, as well as the wall thickness and diameter of temporary diagonal braces. The study examines how these parameters influence the stresses at the tower-girder consolidation. The results indicate that the angle of temporary More >

Mohammed Majid Abed^1,2,*, Murat Aydin¹, Esma Yiğider¹, Melek Ekinci³, Ertan Yildirim³

Phyton-International Journal of Experimental Botany, DOI:10.32604/phyton.2025.073163

Abstract Plants are continuously exposed to abiotic and biotic stresses that threaten their growth, reproduction, and survival. Adaptation to these stresses requires complex regulatory networks that coordinate physiological, molecular, and ecological responses. However, such adaptation often incurs significant costs, including reduced growth, yield penalties, and altered ecological interactions. This review systematically synthesizes recent advances published between 2018 and 2025, following PRISMA criteria, on plant responses to abiotic and biotic stressors, with an emphasis on the trade-offs between adaptation and productivity. It also highlights major discrepancies in the literature and discusses strategies for enhancing plant stress tolerance More >

Cheng-Hsun Chuang^1,2,3,#, Ping-Kun Tsai^3,4,5,6,#, Shih-Wen Kao^7,8, Yu-Hsun Wang^8,9,*, Chao-Bin Yeh^1,2,3,*

Oncology Research, DOI:10.32604/or.2025.072875

Abstract Background: To determine whether initiating a glucagon-like peptide-1 receptor agonist (GLP-1 RA) within 3 months of type 2 diabetes (T2DM) diagnosis alters the subsequent risk of overall and site-specific cancer and whether this association differs by baseline body-mass index (BMI). Methods: This retrospective cohort study used electronic health records from the TriNetX U.S. research network. Adults aged 20 years or older diagnosed with T2DM between 2016 and 2024 were included if they received any hypoglycemic agents within 3 months before and after diagnosis. Following 1:1 propensity score matching, both the GLP-1 RA user and non-user… More > Graphic Abstract

Dongchi Cai^1,2,#, Jialin Ji^3,#, Chunhui Yang^1,*, Hong Cai^1,*

Oncology Research, DOI:10.32604/or.2025.071152

Abstract Metabolic reprogramming involving branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—is increasingly recognized as pivotal in cancer progression, metastasis, and immune modulation. This review comprehensively explores how cancer cells rewire BCAA metabolism to enhance proliferation, survival, and therapy resistance. Tumors manipulate BCAA uptake and catabolism via high expression of transporters like L-type amino acid transporter 1 (LAT1) and enzymes including branched chain amino acid transaminase 1(BCAT1), branched chain amino acid transaminase 2 (BCAT2), branched-chain alpha-keto acid dehydrogenase (BCKDH), and branched chain alpha-keto acid dehydrogenase kinase (BCKDK). These alterations sustain energy production, biosynthesis, redox homeostasis, and oncogenic… More >

Gengan Wu^1,#, Anqi Jiang^1,#, Zihan Chen², Xinwei Su^3,4,*

Journal of Psychology in Africa, DOI:10.32604/jpa.2025.073822

Abstract This study examined the role of role clarity and safety cognition in shaping mountain climbers’ participation motivation and safety behavior. The study sample comprised 454 participants (males = 58.8%, mean age = 32 years, SD = 9.31). They completed measures on five participation motivation dimensions (achievement, interest, knowledge, socialization, and health) and safety participation. The results from structural equation modelling indicated that participant motivations in achievement, health, and knowledge significantly predicted safety participation behavior, such as risk avoidance, self-protection, and mutual assistance, more so than the motivations of interest and socialization. Role clarity moderated the More >

Wufan Jia¹, Seung Hee Yoo², Hye Eun Lee^3,*

International Journal of Mental Health Promotion, DOI:10.32604/ijmhp.2025.071572

Abstract Background: With growing concerns about the abuse of prescription and over-the-counter (OTC) medications, such as medications for attention-deficit/hyperactivity disorder (ADHD), diet pills, and sleep aids, among adolescents in South Korea, this study aimed to investigated how these substances affect key aspects of adolescent well-being, specifically school satisfaction, body image, and sleep quality, and their association with mental health outcomes. Methods: A two-wave longitudinal survey was conducted with Korean female high school students (Wave 1: n = 494; Wave 2: n = 189). Linear regression analyses were used to evaluate the effects of ADHD medications, diet pills, and… More >

Shengzhong Zhao¹, Daiyan Chen¹, Han Zhang^1,2,*, Junhao Yu¹, Lin Xu¹, Zhaoyi Zhuang¹, Fei Wang^1,*

Frontiers in Heat and Mass Transfer, DOI:10.32604/fhmt.2025.071910

Abstract A sealed portal could significantly alter the flame shape and smoke flow characteristics in inclined tunnel fires. In inclined tunnels, two typical sealing conditions could be defined, namely the upper portal sealed and the lower portal sealed. In this study, the effects of tunnel slope on flame shape, flame length, along with smoke mass flow rate and induced velocity at the tunnel portal, are numerically investigated. The results show that, in all scenarios, flames initially rise vertically but tilt toward the sealed portal during the quasi-steady stage, with the largest tilt angle observed in tunnels… More >