Xingjun Meng^1,#, Zhihui Cao^2,#, Renfeng Liu^3,#, Kai Zheng⁴, Shuai Ding⁵, Yuefan Gu⁴, Yonghua Chen⁶, Jun Lv⁷, Ping Li⁸, Li Zhou⁹, Wenbo Wang¹⁰, Shiliang Ji¹¹, Hui He^12,*, Hui Yang^9,*

Oncologie, Vol.24, No.2, pp. 283-294, 2022, DOI:10.32604/oncologie.2022.021259

Abstract It is widely accepted that tumor metastasis is the dominant factor leading to cancer-related death. Tumor metastasis is mediated by cell invasion, blood circulation and lymphatic circulation. Paclitaxel, as a common anti-tumor drug and a mitotic inhibitor, promotes microtubule assembly and inhibits microtubule depolymerization. In addition, ticagrelor, an anti-platelet drug, is used to treat acute coronary syndrome. Increasing numbers of studies have reported that platelets can facilitate tumor metastasis. Therefore, inhibiting the effects of platelets can serve as a novel therapeutic strategy for cancer. To explore the effect of anti-tumor and anti-platelet drugs on tumor progression, we chose paclitaxel and… More >

Yanqing Wu^1,2, Jiao Liu¹, Daqiu Zhao², Jun Tao^1,2,*

Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 2017-2032, 2022, DOI:10.32604/phyton.2022.020643

Abstract Herbaceous peony (Paeonia lactiflora Pall.) is an important ornamental plant worldwide. In its natural state, P. lactiflora often manifests traits like rapidly elongating internodal growth, loose plant types, and soft inflorescence stems. However, very little has been known about the measures for controlling these traits. This study investigated the effect of applying paclobutrazol (PBZ) on the plant growth and flower quality in P. lactiflora. The results indicated that PBZ application reduced the plant height (8.05%), plant crown width (14.72%), and leaf area (10.90%), but increased the leaf thickness (18.18%) and stem diameter (over 11%) in P. lactiflora. Meanwhile, PBZ application… More >

Shaher Alshammrei¹, Sahbi Boubaker^2,*, Lioua Kolsi^1,3

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5939-5954, 2022, DOI:10.32604/cmc.2022.028165

Abstract Optimal path planning avoiding obstacles is among the most attractive applications of mobile robots (MRs) in both research and education. In this paper, an optimal collision-free algorithm is designed and implemented practically based on an improved Dijkstra algorithm. To achieve this research objectives, first, the MR obstacle-free environment is modeled as a diagraph including nodes, edges and weights. Second, Dijkstra algorithm is used offline to generate the shortest path driving the MR from a starting point to a target point. During its movement, the robot should follow the previously obtained path and stop at each node to test if there… More >

Fawad Salam Khan^1,4, Mohd Norzali Haji Mohd^1,*, Saiful Azrin B. M. Zulkifli², Ghulam E Mustafa Abro², Suhail Kazi³, Dur Muhammad Soomro¹

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5741-5759, 2022, DOI:10.32604/cmc.2022.024927

Abstract The evident change in the design of the autopilot system produced massive help for the aviation industry and it required frequent upgrades. Reinforcement learning delivers appropriate outcomes when considering a continuous environment where the controlling Unmanned Aerial Vehicle (UAV) required maximum accuracy. In this paper, we designed a hybrid framework, which is based on Reinforcement Learning and Deep Learning where the traditional electronic flight controller is replaced by using 3D hand gestures. The algorithm is designed to take the input from 3D hand gestures and integrate with the Deep Deterministic Policy Gradient (DDPG) to receive the best reward and take… More >

Yanan Chen^1,2,3,4, Ting Yao^1,4,*, Haiping Ren², Zehao Gan¹

CMES-Computer Modeling in Engineering & Sciences, Vol.131, No.3, pp. 1497-1513, 2022, DOI:10.32604/cmes.2022.019589

Abstract The introduction of the electronic medical record (EHR) sharing system has made a great contribution to the management and sharing of healthcare data. Considering referral treatment for patients, the original signature needs to be converted into a re-signature that can be verified by the new organization. Proxy re-signature (PRS) can be applied to this scenario so that authenticity and nonrepudiation can still be insured for data. Unfortunately, the existing PRS schemes cannot realize forward and backward security. Therefore, this paper proposes the first PRS scheme that can provide key-insulated property, which can guarantee both the forward and backward security of… More >

Vishnu Kumar Kaliappan¹, Tuan Anh Nguyen¹, Dugki Min^2,*, Jae-Woo Lee¹, U. Sakthi³

Intelligent Automation & Soft Computing, Vol.34, No.1, pp. 575-591, 2022, DOI:10.32604/iasc.2022.024577

Abstract In recent years, the applications of rotorcraft-based unmanned aerial vehicles (RUAV) have increased rapidly. In particular, the integration of bio-inspired techniques to enhance intelligence in coordinating multiple Rotorcraft-based Unmanned Aerial Vehicles (RUAVs) has been a focus of recent research and development. Due to the limitation in intelligence, these RUAVs are restricted in flying low altitude with high maneuverability. To make it possible, the RUAVs must have the ability to avoid both static and dynamic obstacles while operating at low altitudes. Therefore, developing a state-of-the-art intelligent control algorithm is necessary to avoid low altitude obstacles and coordinate without collision while executing… More >

Murad A. A. Almekhlafi¹, Taiseer Abdalla Elfadil Eisa², Fahd N. Al-Wesabi^3,4, Abdelzahir Abdelmaboud⁵, Manar Ahmed Hamza^6,*, Abdelwahed Motwakel⁶, Ishfaq Yaseen⁶, Mohammed Rizwanullah⁶

CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 227-242, 2022, DOI:10.32604/cmc.2022.024356

Abstract Line-of-sight clarity and assurance are essential because they are considered the golden rule in wireless network planning, allowing the direct propagation path to connect the transmitter and receiver and retain the strength of the signal to be received. Despite the increasing literature on the line of sight with different scenarios, no comprehensive study focuses on the multiplicity of parameters and basic concepts that must be taken into account when studying such a topic as it affects the results and their accuracy. Therefore, this research aims to find limited values that ensure that the signal reaches the future efficiently and enhances… More >

Saasha Joshi^*, Deepti Gupta

Journal of Quantum Computing, Vol.3, No.4, pp. 137-150, 2021, DOI:10.32604/jqc.2021.018114

Abstract This paper provides an introduction to a quantum search algorithm, known as Grover’s Algorithm, for unsorted search purposes. The algorithm is implemented in a search space of 4 qubits using the Python-based Qiskit SDK by IBM. While providing detailed proof, the computational complexity of the algorithm is generalized to n qubits. The implementation results obtained from the IBM QASM Simulator and IBMQ Santiago quantum backend are analyzed and compared. Finally, the paper discusses the challenges faced in implementation and real-life applications of the algorithm hitherto. Overall, the implementation and analysis depict the advantages of this quantum search algorithm over its… More >

Mohamed Fathy Ahmed¹, Eman Zakaria Ahmed², Salman Aloufi³, Mohammed Alqurashi³, Amal Alyamani³, Eman Fayad³, Eman Tawfik Hussien^2,*

Phyton-International Journal of Experimental Botany, Vol.91, No.4, pp. 889-902, 2022, DOI:10.32604/phyton.2022.018600

Abstract Populus alba is a large woody deciduous plant. The plant has been introduced to shooting, then multiplication of rooting on Murashige and Skoog (MS) medium. This work was designed to estimate the effect of two factors (low levels of 1-Naphthaleneacetic acid NAA and sucrose) on P. alba response resulting in 6 treatments compared to the control, with twelve measured responses. There was a significant difference in some measurements in morphology, like plantlets fresh-weight, shoot-, root-length, and leaf number. In the physiological measurements, there were significant differences in all the measured parameters. The low concentrations of sucrose and media composition/power (MS… More >

Jie Ling^1,2, Xinmei Li^1,2, Mingwei Lin^1,2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.1, pp. 117-148, 2021, DOI:10.32604/cmes.2021.016356

Abstract During the COVID-19 outbreak, the use of single-use medical supplies increased significantly. It is essential to select suitable sites for establishing medical waste treatment stations. It is a big challenge to solve the medical waste treatment station selection problem due to some conflicting factors. This paper proposes a multi-attribute decision-making (MADM) method based on the partitioned Maclaurin symmetric mean (PMSM) operator. For the medical waste treatment station selection problem, the factors or attributes (these two terms can be interchanged.) in the same clusters are closely related, and the attributes in different clusters have no relationships. The partitioned Maclaurin symmetric mean… More >