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  • Open Access

    ARTICLE

    Salicylic Acid-Elicited Alkaloid Accumulation in Pinellia ternata Microtubers: Cytotoxicity and Transcriptomic Analysis

    Xiaoqing Jiang1,2,#, Pengchong Li1,2,#, Hongchuang Liu1,2, Wenjie Dong1,2, Wenjing Liu1,2, Di Wu1,2, Jianping Xue1,2, Fenglan Zhao1,2,*, Yongbo Duan1,2,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074434 - 30 January 2026

    Abstract As its tuberous alkaloids induce valuable pharmacological effects, Pinellia ternata has considerable clinical value. However, its production currently fails to meet its demand. In vitro microtuber culture, combined with salicylic acid (SA) elicitation, may provide an effective alternative to traditional field production. In this study, an in vitro P. ternata microtuber induction system was developed and used to evaluate SA-induced elicitation of alkaloid accumulation. The quality of in vitro microtubers was assessed by total alkaloid measurement, a cytotoxicity assay, and transcriptomic analysis. With or without SA treatment, P. ternata microtuber induction was achieved within 60 d using petiole-derived explants, with… More >

  • Open Access

    ARTICLE

    Evaluation of Strip-Processed Cotton Stalks as a Raw Material for Structural Panels

    Aadarsha Lamichhane1, Arun Kuttoor Vasudevan1, Ethan Dean1, Mostafa Mohammadabadi1,*, Kevin Ragon1, Ardeshir Adeli2

    Journal of Renewable Materials, Vol.14, No.1, 2026, DOI:10.32604/jrm.2025.02025-0146 - 23 January 2026

    Abstract This study explores a novel method for processing cotton stalks—an abundant agricultural byproduct—into long strips that serve as sustainable raw material for engineered bio-based panels. To evaluate the effect of raw material morphology on panel’s performance, two types of cotton stalk-based panels were developed: one using long strips, maintaining fiber continuity, and the other using ground particles, representing conventional processing. A wood strand-based panel made from commercial southern yellow pine strands served as the control. All panels were bonded using phenol-formaldehyde resin and hot-pressed to a target thickness of 12.7 mm and density of 640 kg/m3.… More >

  • Open Access

    REVIEW

    The Yin–Yang of Stress and Senescence: Integrated Stress Response and SASP Crosstalk in Stem Cell Fate, Regeneration, and Disease

    Douglas M. Ruden*

    BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072273 - 23 January 2026

    Abstract Stem cell fate decisions are increasingly understood through the dynamic interplay of two fundamental stress-adaptive programs: the integrated stress response (ISR) and the senescence-associated secretory phenotype (SASP). These pathways act as a Yin–Yang system, balancing beneficial and detrimental outcomes across development, tissue homeostasis, and disease. On the yin (protective) side, transient ISR activation and acute SASP signaling foster adaptation, embryonic patterning, wound healing, and regeneration. On the yang (maladaptive) side, chronic ISR signaling and unresolved SASP output drive stem cell exhaustion, fibrosis, inflammation, and tumorigenesis. This duality highlights their roles as both guardians and disruptors More > Graphic Abstract

    The Yin–Yang of Stress and Senescence: Integrated Stress Response and SASP Crosstalk in Stem Cell Fate, Regeneration, and Disease

  • Open Access

    ARTICLE

    State-Space Reduction Techniques Exploiting Specific Constraints for Quantum Search Initialization, Application to an Outage Planning Problem

    Rodolphe Griset1,#,*, Ioannis Lavdas2,§, Jiří Guth Jarkovský3

    Journal of Quantum Computing, Vol.7, pp. 81-105, 2025, DOI:10.32604/jqc.2025.066064 - 08 December 2025

    Abstract Quantum search has emerged as one of the most promising fields in quantum computing. State-of-the-art quantum search algorithms enable the search for specific elements in a distribution by monotonically increasing the density of these elements relative to the rest of the distribution. These kinds of algorithms demonstrate a theoretical quadratic speed-up on the number of queries compared to classical search algorithms in unstructured spaces. Unfortunately, the major part of the existing literature applies quantum search to problems whose size grows exponentially with the input size without exploiting any specific problem structure, rendering this kind of… More >

  • Open Access

    ARTICLE

    Early Chemodiversity of Alkaloids in Seedlings Annona Species

    Iván De-la-Cruz-Chacón, Christian Anabí Riley-Saldaña, Marisol Castro-Moreno, Claudia Azucena Durán-Ruiz, Alma Rosa González-Esquinca*

    Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3509-3526, 2025, DOI:10.32604/phyton.2025.072586 - 01 December 2025

    Abstract The seedling phase represents an initial and critical stage for the establishment of individuals in the ecosystem. During this stage, specialized metabolites contribute to survival; however, studies analyzing the presence of these molecules and the reasons for their production and accumulation are still scarce. Annonaceae is a botanical family recognized for the chemodiversity of its secondary metabolites; nearly 1000 alkaloids have been reported in approximately 150 adult specimens. The aim of this study was to determine whether alkaloid biosynthesis in Annonaceae is expressed from early stages. For this purpose, Annona macroprophyllata, Annona muricata, Annona purpurea, and Annona reticulata seedlings,… More >

  • Open Access

    ARTICLE

    Exploring Efficiency of Silicon Carbide for Next Generation of Alkali & Alkaline Earth Metals-Ion Batteries Using Quantum Mechanic Method

    Fatemeh Mollaamin1,*, Majid Monajjemi2

    Energy Engineering, Vol.122, No.12, pp. 4971-4986, 2025, DOI:10.32604/ee.2025.069945 - 27 November 2025

    Abstract Delving alternative high-performance anodes for lithium-ion batteries have always attracted scientist attention. A wide-bandgap semiconductor with excellent mechanical properties, “silicon carbide (SiC)”, has been introduced as the anode electrode. Two-dimensional SiC has special hybridization which can build it as an appropriate substitution for graphene. Energy storage technologies are keys in the extension and function of electric devices. To keep up with steady innovations in saving energy technologies, it is essential to progress corresponding practical strategies. In this research article, SiC has been designed and characterized as an anode electrode for lithium (Li), sodium (Na), beryllium… More > Graphic Abstract

    Exploring Efficiency of Silicon Carbide for Next Generation of Alkali & Alkaline Earth Metals-Ion Batteries Using Quantum Mechanic Method

  • Open Access

    ARTICLE

    The Effect of Alkalization Fiber on Mechanical, Microstructure, and Thermal Properties of Sugarcane Bagasse Fiber Reinforced PLA Biocomposite

    Mochamad Asrofi1,*, Muhammad Oktaviano Putra Hastu1, Muhammad Luthfi Al Anshori1, Feyza Igra Harda Putra1, Revvan Rifada Pradiza1, Haris Setyawan1, Muhammad Yusuf1, Mhd Siswanto1, R.A. Ilyas2,3, Muhammad Asyraf Muhammad Rizal3, Salit Mohd Sapuan4, Victor Feizal Knight5, Mohd Nor Faiz Norrrahim5

    Journal of Renewable Materials, Vol.13, No.10, pp. 1979-1992, 2025, DOI:10.32604/jrm.2025.02025-0033 - 22 October 2025

    Abstract Biocomposites are one of the environmentally friendly materials as a substitute for synthetic plastics used for various applications in the automotive, household appliances industry, and interiors. In this study, biocomposites from Polylactic Acid (PLA) and sugarcane bagasse fibers (SBF) were made using the 3D Printing method. The effect of alkalization with NaOH of 0 (untreated), 4%, 6%, and 8% of the fibers were studied. The SBF in PLA was kept at 2% v/v from the total biocomposite. The characterization of all biocomposite tested using tensile, flexural, impact, scanning electron microscope (SEM), thermogravimetric analysis (TGA), and Fourier… More > Graphic Abstract

    The Effect of Alkalization Fiber on Mechanical, Microstructure, and Thermal Properties of Sugarcane Bagasse Fiber Reinforced PLA Biocomposite

  • Open Access

    ARTICLE

    Acetylation of Corn Stalk (Zea mays) for Its Valorization

    Jhony César Muñoz Zambrano, Douglas Alexander Bermúdez Parrales, María Antonieta Riera*

    Journal of Polymer Materials, Vol.42, No.3, pp. 837-851, 2025, DOI:10.32604/jpm.2025.067277 - 30 September 2025

    Abstract Agricultural waste is a potentially interesting resource due to the compounds present. In this study, cellulose was extracted from corn stalks (Zea mays) and subsequently converted into cellulose acetate (CA). Before the extraction process, the waste sample was characterized by pH, moisture, ash, protein content, total reducing sugars (TRS), carbohydrates, cellulose, hemicellulose, and lignin. Acid and alkaline hydrolysis were performed with different reagents, concentrations, and extraction times. Sulfuric acid (H2SO4) and acetic acid (CH3COOH) were used in the acid hydrolysis, while sodium hydroxide (NaOH) was used in the alkaline hydrolysis. Three concentrations (0.62, 1.25, 2.5)% and two… More >

  • Open Access

    ARTICLE

    Parasitic Shunt Currents in Alkaline Water Electrolysis (AWE) for Generating Clean Hydrogen

    Tuhid Pashaee Golmarz1, Seyyed Kazem Yekani1,*, Ebrahim Abdi aghdam2

    Energy Engineering, Vol.122, No.10, pp. 4121-4134, 2025, DOI:10.32604/ee.2025.067446 - 30 September 2025

    Abstract Since the beginning of the 20th century, alkaline electrolysis has been used as a proven method for producing hydrogen on a megawatt scale. The existence of parasitic shunt currents in alkaline water electrolysis, which is utilized to produce clean hydrogen, is investigated in this work. Analysis has been done on a 20-cell stack. Steel end plates, bipolar plates, and an electrolyte concentration of 6 M potassium hydroxide are all included in the model. The Butler-Volmer kinetics equations are used to simulate the electrode surfaces. Ohmic losses are taken into consideration in both the electrode and… More >

  • Open Access

    REVIEW

    Cross-Talk between Next-Generation Probiotics and the Immune System

    Mikhail Syromyatnikov1,2,*, Mariya Gladkikh1, Ekaterina Nesterova1, Shima Kazemzadeh1, Polina Morozova1, Olga Korneeva1

    BIOCELL, Vol.49, No.9, pp. 1573-1603, 2025, DOI:10.32604/biocell.2025.065311 - 25 September 2025

    Abstract The gut microbiome is a complex community of microorganisms that plays a direct role in the health of both the gastrointestinal tract and the entire body. Numerous factors influence the abundance and diversity of gut microbiota. Microbial imbalance can contribute to disease development. Probiotics are biologically active supplements with promising properties that have high therapeutic potential. Currently, there is a tendency to switch from classic probiotic microorganisms represented by lactic acid bacteria to next-generation probiotics due to their unique ability to influence the human immune system. New-generation probiotics include bacteria such as Akkermansia muciniphila, Faecalibacterium prausnitzii, Bacteroides sp., More >

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