Shengda Chen^1,2, Candra Ratna Sari¹, Patrick Segers², Guixue Wang¹, Xingshuang Ma^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 69-70, 2019, DOI:10.32604/mcb.2019.05740

Abstract This article has no abstract. More >

Guangyu Zhu¹, Wei Cai^2,*, Qi Yuan¹, Lianglong Chen²

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 59-60, 2019, DOI:10.32604/mcb.2019.05733

Abstract This article has no abstract. More >

Yifan Yin¹, Chunliu He¹, Biao Xu², Zhiyong Li^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 57-57, 2019, DOI:10.32604/mcb.2019.05732

Abstract The tissue composition and morphological structure of atherosclerotic plaques determine its stability or vulnerability. Intravascular optical coherence tomography (IVOCT) has rapidly become the method of choice for assessing the pathology of the coronary arterial wall in vivo due to its superior resolution. However, in clinical practice, the analysis of plaque composition of OCT images mainly relies on the interpretation of images by well-trained experts, which is a time-consuming, labor-intensive procedure and it is also subjective. The purpose of this study is to use the Convolutional neural network (CNN) method to automatically extract the best feature… More >

Guangyu Zhu¹, Yuan Wei¹, Qi Yuan^1,*, Ge Yan², Jian Yang²

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 55-56, 2019, DOI:10.32604/mcb.2019.05730

Abstract This article has no abstract. More >

Kun Peng¹, Xinyang Cui¹, Aike Qiao^1,*, Makoto Ohta², Koji Shimoyama², Yongliang Mu³

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 53-53, 2019, DOI:10.32604/mcb.2019.05729

Abstract Biodegradable stents which can avoid risks caused by incompatibility between artery and permanent stents are attracting much interests. However, biodegradable stents have not been extensively applied in clinical therapy because of their insufficient scaffold performance as a result of poor Young’s Modulus of biodegradable materials and weaken structures in degradation process. In this study, a patented stent and a common stent were simulated to degrade in a 40% stenotic vesel based on a corrosion model involving uniform corrosion and stress corrosion. In the degradation process, the scaffold performance of the two stents and their functionality… More >

Zhi Zhang¹, Jianhua Tong^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 43-43, 2019, DOI:10.32604/mcb.2019.05721

Abstract Diabetes is a major risk factor to cause macrovascular diseases and plays a pivotal role in aortic wall remodeling. However, the effects of diabetes on elastic properties of aortas remain largely unknown. Thirty adult rabbits (1.6-2.2 kg) were collected and the type I diabetic rabbit model was induced by injection of alloxan. A total of 15 control and 15 diabetic rabbit (abdominal) aortas were harvested. Uniaxial and biaxial tensile tests were performed to measure ultimate tensile strength and to characterize biaxial mechanical behaviors of the aortas. A material model was fitted to the biaxial experimental… More >

Longling Fan¹, Jing Yao², Chun Yang³, Di Xu², Dalin Tang^1,4,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 41-41, 2019, DOI:10.32604/mcb.2019.05720

Abstract Cardiac pacing has been an effective treatment in the management of patients with arrhythmia. Different pacemaker location may have different impact on pacemaker effectiveness. A novel image-based ventricle animal modeling approach was proposed to integrate echocardiography images, propagating dynamic electric potential on ventricle surface to perform myocardial function assessment. The models will be used to simulate ventricular electrical signal conduction and optimize pacemaker location for better cardiac outcome. One health female adult pig weight 42.5 kg was used to make pacing animal model with different ventricle pacing locations. Pig health status was assessed before undergoing… More >

Da Li^1,#, Liqing Peng^2,#, Yi Wang³, Ding Yuan⁴, Tinghui Zheng^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 39-39, 2019, DOI:10.32604/mcb.2019.05718

Abstract Objective: Thoracic endovascular aortic repair (TEVAR) of type B aortic dissection (AD) is to initiate the thrombosis in the false lumen to eventually result in aortic remodeling. We aim to find out whether the false lumen (FL) thrombosis rate after TEVAR can be predicted accurately by an index that expresses the degree of aortic arch angulation. Method: Three-dimensional aortic arch geometry of 39 type B AD patients (mean age: 48 years) after TEVR were reconstructed from post-operative CT images. For the first time, the question mark which takes into account the curvature of both aortic arch… More >

Aike Qiao^1,*, Honghui Zhang¹, Jun Xia¹

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 35-35, 2019, DOI:10.32604/mcb.2019.05715

Abstract In order to improve the calculation accuracy of computed tomography angiography-derived fractional flow reserve (FFR_CT), a mathematical model for setting the patient-specific flow boundary condition was proposed, in which some independent physiological parameters, such as myocardial mass, diastolic blood pressure, heart rate and vessel volume were considered. This model was employed to simulate hemodynamics in sixteen patients with coronary stenosis. The results of FFR_CT demonstrated good consistency with invasively measured FFR. The diagnostic accuracy of FFR_CT was 85%. The proposed model offers a new approach to improve the accuracy of FFR_CT, as well as promotes the clinical More >

Fuyou Liang^1,*, Tianqi Wang¹

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 25-26, 2019, DOI:10.32604/mcb.2019.05710

Abstract Hepatic venous pressure gradient (HVPG) measurement has been increasingly accepted as a useful means for indirectly measuring portal venous pressure in patients with portal hypertension (PHT) caused by chronic liver diseases. Despite the existence of numerous studies addressing the clinical utility of HVPG measurement, it is as yet unclear how the accuracy of measured HVPG as a surrogate of portal pressure gradient (PPG) is influenced by the pathological status of the hepatic circulation that not only changes with the progression of liver disease but also differs considerably among patients. In addition, it remains unclear whether… More >