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  • Open Access

    ARTICLE

    The role of echocardiography for quantitative assessment of right ventricular size and function in adults with repaired tetralogy of Fallot

    Alexander C. Egbe, Sorin V. Pislaru, Srikanth Kothapalli, Raja Jadav, Muhammad Masood, Mounika Angirekula, Patricia A. Pellikka

    Congenital Heart Disease, Vol.14, No.5, pp. 700-705, 2019, DOI:10.1111/chd.12783

    Abstract Background: Quantitative assessment of right ventricular (RV) systolic function by echocardiography is challenging in patients with congenital heart disease because of the complex geometry of the RV and the iatrogenic structural abnormalities resulting from prior cardiac surgeries. The purpose of this study was to determine the correla‐ tion between echocardiographic indices of RV systolic function and cardiac magnetic resonance imaging (CMRI) derived RV ejection fraction (RVEF) in adults with repaired tetralogy of Fallot (TOF).
    Methods: Quantitative assessment of RV function was performed with RV tissue Doppler systolic velocity (RV s'), tricuspid annular plane systolic excursion (TAPSE), and… More >

  • Open Access

    ARTICLE

    The clinical characteristics of coronary artery fistula anomalies in children and adults: A 24‐year experience

    Kieu T. Huynh1, Vien T. Truong2,3, Tam N. M. Ngo3,4, Thao B. Dang5, Wojciech Mazur3, Eugene S. Chung3,6, Justin T. Tretter7, Dean J. Kereiakes3, Tuyen K. Le8, Vinh N. Pham1

    Congenital Heart Disease, Vol.14, No.5, pp. 772-777, 2019, DOI:10.1111/chd.12781

    Abstract Objectives: The aim of our work is to investigate the clinical characteristics of coro‐ nary artery fistula (CAF) anomalies in South Vietnam.
    Methods: This is a retrospective analysis of 119 patients with diagnosis of definite CAF between January 1992 and April 2016. The demographic, clinical, echocardio‐ graphic, and angiographic characteristics and management of CAF with short‐term outcomes are described.
    Results: The median age was 15 years (range, 1‐79 years), with 49 male (41%) and 70 female (59%). There were 77 symptomatic patients (64.7%) and 91 patients (76.5%) who presented with a murmur. The electrocardiogram was abnormal in 45.4%… More >

  • Open Access

    ARTICLE

    Health care‐associated infections are associated with increased length of stay and cost but not mortality in children undergoing cardiac surgery

    Sarah Tweddell, Rohit S. Loomba, David S. Cooper, Alexis L. Benscoter

    Congenital Heart Disease, Vol.14, No.5, pp. 785-790, 2019, DOI:10.1111/chd.12779

    Abstract Introduction: Health care‐associated infections (HAIs) increase mortality, length of stay, and cost in hospitalized patients. The incidence of and risk factors for developing HAIs in the pediatric population after cardiac surgery have been studied. This study evaluates the impact of HAIs on length of stay, inpatient mortality, and cost of hospitalization in the pediatric population after cardiac surgery.
    Methods: TheKids’InpatientDatabasewasqueriedforanalysis.Patientsunder18years of age who underwent cardiac surgery from 1997 to 2012 were included. HAIs were defined as central line‐associated blood stream infections, catheter‐associated urinary tract infections, ventilator‐associated pneumonias, and surgical wound infections. Univariate analysis compared admissions with and… More >

  • Open Access

    ARTICLE

    Parental anxiety before invasive cardiac procedure in children with congenital heart disease: Contributing factors and consequences

    Oscar Werner1, Fedoua El Louali2, Virginie Fouilloux3, Pascal Amedro1,4, Caroline Ovaert2,5

    Congenital Heart Disease, Vol.14, No.5, pp. 778-784, 2019, DOI:10.1111/chd.12777

    Abstract Objective: Medical information provided to parents of a child with a congenital heart disease can induce major stress. Visual analog scales have been validated to assess anxiety in the adult population. The aim of this study was to analyze parental anxiety using a visual analog scale and to explore the influencing factors.
    Design: This prospective cross‐sectional study.
    Setting: Tertiary care regional referral center for congenital heart disease of Marseille—La Timone university hospital.
    Patients: Parents of children with a congenital heart disease, as defined by the ACC‐ CHD classification, referred for cardiac surgery or interventional cardiac catheterization, were offered to… More >

  • Open Access

    ARTICLE

    Comparison of creatinine and cystatin C for estimation of glomerular filtration rate in pediatric patients after Fontan operation

    Danielle Kirelik1,2, Mark Fisher2, Michael DiMaria2, Danielle E. Soranno3, Katja M. Gist2

    Congenital Heart Disease, Vol.14, No.5, pp. 760-764, 2019, DOI:10.1111/chd.12776

    Abstract Background: There are several limitations when using creatinine to estimate glomerular filtration rate, especially in children with chronic medical conditions who are at high risk of kidney dysfunction. Cystatin C has been the recent focus of research as a replacement biomarker for creatinine. Our objective was to compare the 2 biomarkers in pediatric single‐ventricle heart disease patients who have undergone the Fontan operation. We hypothesized that there would be poor correlation and agreement between the 2 estimates of renal function.
    Methods: This was a single center retrospective chart review of 20 patients who had previously undergone Fontan… More >

  • Open Access

    ARTICLE

    Hand‐held echocardiography in children with hypoplastic left heart syndrome

    Alan F. Riley1, Elena C. Ocampo1, Joseph Hagan2, M. Regina Lantin‐Hermoso1

    Congenital Heart Disease, Vol.14, No.5, pp. 706-712, 2019, DOI:10.1111/chd.12774

    Abstract Background: When performed by cardiologists, hand‐held echocardiography (HHE) can assess ventricular systolic function and valve disease in adults, but its accuracy and utility in congenital heart disease is unknown. In hypoplastic left heart syndrome (HLHS), the echocardiographic detection of depressed right ventricular (RV) systolic function and higher grade tricuspid regurgitation (TR) can identify patients who are at increased risk of morbidity and mortality and who may benefit from additional imaging or medical therapies.
    Methods: Children with HLHS after Stage I or II surgical palliation (Norwood or Glenn procedures) were prospectively enrolled. Subjects underwent HHE by a pediatric… More >

  • Open Access

    ARTICLE

    Serial assessment of postoperative ventricular mechanics in young children with tetralogy of Fallot: Comparison of transannular patch and valve‐sparing repair

    Vidhya Annavajjhala1, Rajesh Punn1, Theresa A. Tacy1, Frank L. Hanley2, Doff B. McElhinney2

    Congenital Heart Disease, Vol.14, No.5, pp. 691-699, 2019, DOI:10.1111/chd.12772

    Abstract Background: Little is known about the early time course of biventricular function and mechanics after tetralogy of Fallot (TOF) repair. We sought to evaluate and describe the evolution of the right ventricle (RV) after TOF repair in young infants and children using conventional echocardiographic parameters and global longitudinal strain (GLS).
    Methods: A retrospective review was performed of all patients with TOF and pulmo‐ nary stenosis who underwent repair from January 2002 to September 2015 and had at least 3 serial postsurgical echocardiograms spanning from infancy to early child‐ hood (<8 years). Student’s t test was performed to… More >

  • Open Access

    ARTICLE

    Strategy of treating secundum atrial septal defect not referred to percutaneous closure

    Fei Zhang1, Yifeng Yang2, Qin Wu2, Wancun Jin2, Haisong Bu2, Sijie Wu2, Tianli Zhao2, Shijun Hu2

    Congenital Heart Disease, Vol.14, No.3, pp. 324-330, 2019, DOI:10.1111/chd.12753

    Abstract Objective: To evaluate safety and effectiveness of intraoperative device closure for secundum atrial septal defect (ASD) not referred to percutaneous closure.
    Design and Patients: From April 2010 to December 2018, 231 secundum ASD children (≤14 years) directly recommended to surgical repair were enrolled in this study. These patients were divided into two groups according to the parents’ choice based on surgeons’ recommendation. Follow-up evaluations were adopted at 2 weeks, 3 months, 6 months, and 12 months after the procedure and yearly thereafter. In Group A, 127 patients underwent an initial attempt at device closure. In Group B,… More >

  • Open Access

    ARTICLE

    Body mass index in adults with congenital heart disease

    Mahmoud Zaqout1,2, Kristof Vandekerckhove1, Nathalie Michels2, Laurent Demulier3, Thierry Bove4, Katrien François4, Julie De Backer3, Stefaan De Henauw2, Daniel De Wolf1

    Congenital Heart Disease, Vol.14, No.3, pp. 479-486, 2019, DOI:10.1111/chd.12751

    Abstract Objective: To investigate the status of body mass index (BMI) in adult people with congenital heart disease (ACHD).
    Methods: Five hundred thirty‐nine adults with CHD (53.8% men) were seen in the outpatient clinic from 2013 to 2015 and compared to a reference population (n = 1737). The severity of CHD was categorized as mild, moderate, and severe ac‐ cording to standard guidelines. Patients were categorized based on BMI as under‐ weight (<18.5), overweight (25‐30), or obese (>30). Echocardiography and magnetic resonance imaging were used to measure ventricular function while exercise capac‐ ity was estimated via cardiopulmonary exercise… More >

  • Open Access

    ARTICLE

    A better approach for left ventricular training in transposition of the great arteries and intact interventricular septum: Bidirectional cavopulmonary anastomosis and pulmonary artery banding

    Mehmet Salih Bilal1, Arda Özyüksel1,2, Mustafa Kemal Avşar1, Şener Demiroluk3, Osman Küçükosmanoğlu4, Yalım Yalçın5

    Congenital Heart Disease, Vol.14, No.3, pp. 464-469, 2019, DOI:10.1111/chd.12749

    Abstract Objective: Management of the patients with transposition of the great arteries and intact ventricular septum may be challenging beyond the newborn period. Herein, we would like to present our alternative strategy for training the left ventricle in these patients.
    Methods: Six patients with transposition of the great arteries and intact ventricular septum were evaluated in our clinic. Two of them were palliated with Glenn procedure and pulmonary banding as a definitive treatment strategy at other centers. Four patients were operated on and a bidirectional cavopulmonary anastomosis in combination with pulmonary artery banding was performed (stage‐1: palliation and… More >

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