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  • Open Access

    ARTICLE

    Chloroplast Genome Sequence Characterization and Phylogenetic Analysis of Pyrola Atropurpurea Franch

    Wentao Sheng*

    Phyton-International Journal of Experimental Botany, Vol.94, No.2, pp. 331-345, 2025, DOI:10.32604/phyton.2025.061424 - 06 March 2025

    Abstract Pyrola atropurpurea Franch is an important annual herbaceous plant. Few genomic analyses have been conducted on this plant, and chloroplast genome research will enrich its genomics basis. This study is based on high-throughput sequencing technology and Bioinformatics methods to obtain the sequence, structure, and other characteristics of the P. atropurpurea chloroplast genome. The result showed that the chloroplast genome of P. atropurpurea has a double-stranded circular structure with a total length of 172,535 bp and a typical four-segment structure. The genome has annotated a total of 132 functional genes, including 43 tRNAs, 8 rRNAs, 76 protein-coding genes, and… More >

  • Open Access

    ARTICLE

    Magnetic melamine cross-linked polystyrene-alt-malic anhydride copolymer: Synthesis, characterization, paclitaxel delivery, cytotoxic effects on human ovarian and breast cancer cells

    RAZIEH MOMEN-MESGIN1, JAFAR REZAIE2,*, VAHID NEJATI1, PEYMAN NAJAFI MOGHADAM3

    Oncology Research, Vol.33, No.3, pp. 665-674, 2025, DOI:10.32604/or.2024.054487 - 28 February 2025

    Abstract Objectives: Due to systematic side effects, there is a growing interest in nanoparticle formulation of anticancer drugs. Here, we aimed to synthesize poly (styrene-alt-maleic anhydride) cross-linked by melamine (PSMA/Me) and coated with magnetite nanoparticles (MNPs) PSMA/Me/Fe3O4. In addition, we aimed to load paclitaxel (PTX) into PSMA/Me/Fe3O4 for drug delivery and anticancer investigations. Methods: Novel PSMA/Me was synthesized via free radical copolymerization, coated with Fe3O4, and then used as a transporter for PTX delivery. Fabricated copolymer was characterized using SEM, TGA, and XRD techniques. Drug release rate and loading efficiency were investigated. Human ovarian cancer cells (Skov-3) and… More >

  • Open Access

    ARTICLE

    Synchronization Characterization of DC Microgrid Converter Output Voltage and Improved Adaptive Synchronization Control Methods

    Wei Chen, Xin Gao*, Zhanhong Wei, Xusheng Yang, Zhao Li

    Energy Engineering, Vol.122, No.2, pp. 805-821, 2025, DOI:10.32604/ee.2025.059779 - 31 January 2025

    Abstract This paper deeply introduces a brand-new research method for the synchronous characteristics of DC microgrid bus voltage and an improved synchronous control strategy. This method mainly targets the problem of bus voltage oscillation caused by the bifurcation behavior of DC microgrid converters. Firstly, the article elaborately establishes a mathematical model of a single distributed power source with hierarchical control. On this basis, a small-world network model that can better adapt to the topology structure of DC microgrids is further constructed. Then, a voltage synchronization analysis method based on the main stability function is proposed, and… More >

  • Open Access

    ARTICLE

    Characterization of Physico-Chemical Changes of Lignin Obtained under Different Conditions of Enzymatic Hydrolysis on an Industrial Scale

    Maris Lauberts1,*, Janis Rizikovs1, Matiss Pals1, Karl Pebo2

    Journal of Renewable Materials, Vol.13, No.1, pp. 115-126, 2025, DOI:10.32604/jrm.2024.056815 - 20 January 2025

    Abstract Research-based on lignin as a bioproduct has grown due to its high availability, reactivity, physicochemical stability, and abundance of different aromatic units. Lignin consists of various functional groups, which can react in various chemical reactions and serve as a raw material in various processes to obtain multiple products. These characteristics make lignin suitable for synthesizing products from natural raw materials, replacing fossil ones. Due to a high aromatic variety and complex structural arrangement, lignin isolation and fractionation are still challenging. The aim and novelty of this work was the modification of severity and enzymatic hydrolysis… More >

  • Open Access

    ARTICLE

    Comprehensive molecular characterization to predict immunotherapy response in advanced biliary tract cancer: a phase II trial of pembrolizumab

    RYUL KIM1,#, JOO KYUNG PARK2,#, MINSUK KWON3, MINAE AN4, JUNG YONG HONG1, JOON OH PARK1, SUNG HEE LIM1,*, SEUNG TAE KIM1,*

    Oncology Research, Vol.33, No.1, pp. 57-65, 2025, DOI:10.32604/or.2024.049054 - 20 December 2024

    Abstract Background: Immune checkpoint inhibitors (ICIs) are effective in a subset of patients with metastatic solid tumors. However, the patients who would benefit most from ICIs in biliary tract cancer (BTC) are still controversial. Materials and methods: We molecularly characterized tissues and blood from 32 patients with metastatic BTC treated with the ICI pembrolizumab as second-line therapy. Results: All patients had microsatellite stable (MSS) type tumors. Three of the 32 patients achieved partial response (PR), with an objective response rate (ORR) of 9.4% (95% confidence interval [CI], 2.0–25.2) and nine showed stable disease (SD), exhibiting a disease… More >

  • Open Access

    ARTICLE

    Multi-Step Clustering of Smart Meters Time Series: Application to Demand Flexibility Characterization of SME Customers

    Santiago Bañales1,2,*, Raquel Dormido1, Natividad Duro1

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.1, pp. 869-907, 2025, DOI:10.32604/cmes.2024.054946 - 17 December 2024

    Abstract Customer segmentation according to load-shape profiles using smart meter data is an increasingly important application to vital the planning and operation of energy systems and to enable citizens’ participation in the energy transition. This study proposes an innovative multi-step clustering procedure to segment customers based on load-shape patterns at the daily and intra-daily time horizons. Smart meter data is split between daily and hourly normalized time series to assess monthly, weekly, daily, and hourly seasonality patterns separately. The dimensionality reduction implicit in the splitting allows a direct approach to clustering raw daily energy time series… More > Graphic Abstract

    Multi-Step Clustering of Smart Meters Time Series: Application to Demand Flexibility Characterization of SME Customers

  • Open Access

    ARTICLE

    Characterization and Genetic Diversity of Tea (Camellia sinensis (L.) O. Kuntze) Genotypes for Waterlogging Tolerance

    Md. Riyadh Arefin1,2, Md. Sabibul Haque1, A. K. M. Golam Sarwar1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.12, pp. 3411-3442, 2024, DOI:10.32604/phyton.2024.058893 - 31 December 2024

    Abstract Tea estates in Bangladesh are currently experiencing frequent waterlogging stress due to heavy rainfall or flooding under changing climate scenarios. The development of waterlogging-tolerant tea cultivars is, therefore, crucial for sustainable tea production with increased yield in waterlogging-affected areas. In this study, a total of two hundred tea genotypes were screened for waterlogging tolerance based on yield and quality potentials. Tea genotypes were raised at the nursery and evaluated with 13 traits at the seedling and mature stages. Descriptive and multivariate analysis of the recorded data of measured traits were performed for clustering the… More >

  • Open Access

    ARTICLE

    Preparation and Characterization of Hydrogel Materials Based on the Hydrothermal Liquefaction of Enteromorpha prolifera

    Jiangyi Zhou, Bin Cao, Sivakumar Esakkimuthu, Mao Mu*, Shuang Wang*

    Journal of Renewable Materials, Vol.12, No.12, pp. 2069-2078, 2024, DOI:10.32604/jrm.2024.054905 - 20 December 2024

    Abstract Seaweed, as a third generation of biomass energy, has significant potential to replace non-renewable fossil fuels. Among various conversion technologies, hydrothermal liquefaction can effectively convert seaweed into bio-oil. However, most current research on hydrothermal liquefaction products focuses on the oil phase and solid phase, with little attention given to the utilization of the aqueous phase by-product. In this study, the large seaweed Enteromorpha prolifera was selected as the raw material. The aqueous phase containing organic components was prepared through hydrothermal liquefaction at different temperatures, which was then mixed with the polymer polyvinyl alcohol to produce high-value… More >

  • Open Access

    ARTICLE

    Sustainable Composite of Cardanol Based Phenalkamine Cured Epoxy Systems: Fabrication, Characterization and Mechanical Performance Evaluation for Emerging Applications

    Aswinraj Anbazhagan1, Piyali Roy Choudhury1, Sahila Sambandam2, Jayakumari Lakshmanan Saraswathi1,*

    Journal of Polymer Materials, Vol.41, No.4, pp. 299-313, 2024, DOI:10.32604/jpm.2024.056261 - 16 December 2024

    Abstract Petroleum-based cured epoxy polymers, used widely in aerospace, marine, and automotive industries, pose environmental threats due to their toxicity. Therefore, developing alternative curing systems for epoxy resin is crucial. This study explores the use of bio-based phenalkamines as curing agents for epoxy resin to enhance the mechanical properties of polymer composites and fiber-reinforced laminates. The functional groups, morphology, and thermal properties of the composites were analyzed using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). Mechanical properties of two epoxy systems—EP-TETA (triethylenetetramine-cured) and EP-PA (phenalkamine-cured)—were evaluated according to ASTM standards. More > Graphic Abstract

    Sustainable Composite of Cardanol Based Phenalkamine Cured Epoxy Systems: Fabrication, Characterization and Mechanical Performance Evaluation for Emerging Applications

  • Open Access

    VIEWPOINT

    Recent Breakthroughs in the Characterization of Abscisic Acid Efflux Transporters: Shedding New Light on Abscisic Acid Dynamics and Regulation

    Ivan Couée*

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2707-2714, 2024, DOI:10.32604/phyton.2024.058101 - 30 November 2024

    Abstract The 15-carbon terpenoid abscisic acid (ABA) acts in vascular plants as a versatile hormone playing essential roles in reproductive development, vegetative development and growth, stress-development interactions, and physiological responses to abiotic and biotic stresses. Over the past 60 years, ABA dynamics, regulation, and responses have been progressively characterized: synthesis, transport and translocation, conjugation and deconjugation, metabolism, sensing, signal transduction, and downstream responses. In this context, the discovery of ABA exporters and importers has added novel dimensions to the understanding of ABA regulation. Moreover, since the initial discovery of the adenosine triphosphate-binding cassette (ABC) AtABCG25 exporter… More >

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