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  • Open Access

    ARTICLE

    RoGRUT: A Hybrid Deep Learning Model for Detecting Power Trapping in Smart Grids

    Farah Mohammad1,*, Saad Al-Ahmadi2, Jalal Al-Muhtadi1,2

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3175-3192, 2024, DOI:10.32604/cmc.2023.042873

    Abstract Electricity theft is a widespread non-technical issue that has a negative impact on both power grids and electricity users. It hinders the economic growth of utility companies, poses electrical risks, and impacts the high energy costs borne by consumers. The development of smart grids is crucial for the identification of power theft since these systems create enormous amounts of data, including information on client consumption, which may be used to identify electricity theft using machine learning and deep learning techniques. Moreover, there also exist different solutions such as hardware-based solutions to detect electricity theft that may require human resources and… More >

  • Open Access

    ARTICLE

    LA-D-B1, a novel Abemaciclib derivative, exerts anti-breast cancer effects through CDK4/6

    LING MA1,#, ZIRUI JIANG1,#, XIAO HOU1, YUTING XU1, ZIYUN CHEN1, SIYI ZHANG1, HANXUE LI1, SHAOJIE MA1, GENG ZHANG2, XIUJUN WANG1,*, JING JI1,*

    BIOCELL, Vol.48, No.5, pp. 847-860, 2024, DOI:10.32604/biocell.2024.050868

    Abstract Background: Regulatory proteins involved in human cellular division and proliferation, cyclin-dependent kinases 4 and 6 (CDK4/6) are overexpressed in numerous cancers, including triple-negative breast cancer (TNBC). TNBC is a common pathological subtype of breast cancer that is prone to recurrence and metastasis, and has a single treatment method. As one of the CDK4/6 inhibitors, abemaciclib can effectively inhibit the growth of breast tumors. In this study, we synthesized LA-D-B1, a derivative of Abemaciclib, and investigated its anti-tumor effects in breast cancer. Methods: Cellular viability was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Cell cloning and migration abilities were determined by… More >

  • Open Access

    REVIEW

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

    VIRAAJ VISHNU PRASAD, JENNIFER SALLY SAMSON, VENKATACHALAM DEEPA PARVATHI*

    BIOCELL, Vol.48, No.5, pp. 693-706, 2024, DOI:10.32604/biocell.2024.048776

    Abstract Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an individual. In addition to aiding the regulation of aerobic and anaerobic metabolism, exercise can stimulate the synthesis of exerkine hormones in the circulatory system. Among several exerkines that have been investigated for their therapeutic potential, Brain-derived neurotrophic factor (BDNF) is considered the most promising candidate, especially in the management of neurodegenerative diseases. Owing to the ability of physical activity to enhance BDNF synthesis, several experimental studies conducted so far have validated this hypothesis and produced satisfactory results at the pre-clinical level. This review… More > Graphic Abstract

    Exercise and exerkine upregulation: Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

  • Open Access

    ARTICLE

    Galectin 2 regulates JAK/STAT3 signaling activity to modulate oral squamous cell carcinoma proliferation and migration in vitro

    XINRU FENG1, LI XIAO2,*

    BIOCELL, Vol.48, No.5, pp. 793-801, 2024, DOI:10.32604/biocell.2024.048395

    Abstract Background: Galectin 2 (LGALS2) is a protein previously reported to serve as a mediator of disease progression in a range of cancers. The function of LGALS2 in oral squamous cell carcinoma (OSCC), however, has yet to be explored, prompting the present study to address this literature gap. Methods: Overall, 144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western immunoblotting. The LGALS2 coding sequence was introduced into the pcDNA3.0 vector, to enable the overexpression of this gene, while an LGALS2-specific shRNA and corresponding controls were also obtained.… More >

  • Open Access

    ARTICLE

    Knockdown of RCN1 contributes to the apoptosis of colorectal cancer via regulating IP3R1

    XUAN SHI1,2, YUFEN WANG1, CHENYU LI1, WANGSHU FU3, XINYUE ZHANG3, AIXIA GONG1,*

    BIOCELL, Vol.48, No.5, pp. 835-845, 2024, DOI:10.32604/biocell.2024.048076

    Abstract Background: The incidence of colorectal cancer (CRC) has been increasing in recent years. Thus, the discovery of factors that can assist in alleviating CRC is urgently warranted. Methods: To identify a potential factor involved in the development of CRC, we screened the upregulated genes in tumor tissues through four datasets from an online database. The expression of reticulocalbin 1 (RCN1), a Ca-binding protein, was upregulated in the four datasets. Based on loss-of-function experiments, the effect of RCN1 on cell viability was assessed by Cell Counting Kit-8 (CCK-8) assay. The regulatory effect of RCN1 on apoptosis was evaluated through Annexin V-fluorescein… More > Graphic Abstract

    Knockdown of RCN1 contributes to the apoptosis of colorectal cancer via regulating IP3R1

  • Open Access

    ARTICLE

    Development of Spectral Features for Monitoring Rice Bacterial Leaf Blight Disease Using Broad-Band Remote Sensing Systems

    Jingcheng Zhang1, Xingjian Zhou1, Dong Shen1, Qimeng Yu1, Lin Yuan2,*, Yingying Dong3

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 745-762, 2024, DOI:10.32604/phyton.2024.049734

    Abstract As an important rice disease, rice bacterial leaf blight (RBLB, caused by the bacterium Xanthomonas oryzae pv. oryzae), has become widespread in east China in recent years. Significant losses in rice yield occurred as a result of the disease’s epidemic, making it imperative to monitor RBLB at a large scale. With the development of remote sensing technology, the broad-band sensors equipped with red-edge channels over multiple spatial resolutions offer numerous available data for large-scale monitoring of rice diseases. However, RBLB is characterized by rapid dispersal under suitable conditions, making it difficult to track the disease at a regional scale with… More >

  • Open Access

    REVIEW

    Research Progress on the Growth-Promoting Effect of Plant Biostimulants on Crops

    Qi Lu1,2, Longfei Jin2, Cuiling Tong3, Feng Liu2, Bei Huang2, Dejian Zhang1,2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 661-679, 2024, DOI:10.32604/phyton.2024.049733

    Abstract A Plant Biostimulant is any substance or microorganism applied to plants to enhance nutrition efficiency, abiotic stress tolerance, and/or crop quality traits, regardless of its nutrient content. The application of Plant biostimulants (PBs) in production can reduce the application of traditional pesticides and chemical fertilizers and improve the quality and yield of crops, which is conducive to the sustainable development of agriculture. An in-depth understanding of the mechanism and effect of various PBs is very important for how to apply PBs reasonably and effectively in the practice of crop production. This paper summarizes the main classification of PBs; The growth… More >

  • Open Access

    REVIEW

    Plant Chemical Defenses against Insect Herbivores—Using the Wild Tobacco as a Model

    Guangwei Sun1,2,#, Xuanhao Zhang3,#, Yi Liu3, Liguang Chai2, Daisong Liu2, Zhenguo Chen1,*, Shiyou Lü3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 641-659, 2024, DOI:10.32604/phyton.2024.049285

    Abstract The Nicotiana genus, commonly known as tobacco, holds significant importance as a crucial economic crop. Confronted with an abundance of herbivorous insects that pose a substantial threat to yield, tobacco has developed a diverse and sophisticated array of mechanisms, establishing itself as a model of plant ecological defense. This review provides a concise overview of the current understanding of tobacco’s defense strategies against herbivores. Direct defenses, exemplified by its well-known tactic of secreting the alkaloid nicotine, serve as a potent toxin against a broad spectrum of herbivorous pests. Moreover, in response to herbivore attacks, tobacco enhances the discharge of volatile… More >

  • Open Access

    ARTICLE

    Effects of Potassium-Solubilizing Bacteria on Growth, Antioxidant Activity and Expression of Related Genes in Fritillaria taipaiensis P. Y. Li

    Jiaqi Lang1, Mingyan Ye1, Ya Luo1, Yueheng Wang1, Zhifen Shi1,2, Xiaotian Kong1,3, Xuan Li1, Nong Zhou1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 789-806, 2024, DOI:10.32604/phyton.2024.049088

    Abstract This study aimed to examine the effects of inoculating Fritillaria taipaiensis P.Y.Li leaves with different strains of potassium-solubilizing bacteria (KSB), or combinations thereof, focusing on aspects of photosynthesis and physiological and biochemical characteristics. At present, some studies have only studied the rhizosphere microbial community characteristics of F. taipaiensis and have not discussed the effects of different microbial species on the growth promotion of F. taipaiensis. This paper will start from the perspective of potassium-solubilizing bacteria to conduct an in-depth study. Seed cultivation commenced at the base with three different KSBs in early October 2022. The growth of F. taipaiensis leaves… More >

  • Open Access

    ARTICLE

    Preparation of Tartary Buckwheat Seed Coating Agent and Its Effect on Germination

    Xin Zou1, Jieyu Zhang1, Ting Cheng1, Yangyang Guo1, Xiao Han1, Han Liu1, Yuxing Qin1, Jie Li2, Dabing Xiang1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 699-712, 2024, DOI:10.32604/phyton.2024.048469

    Abstract To mitigate the wastage of seed resources and reduce the usage of pesticides and fertilizers, seed coating agents have gained popularity. This study employs single-factor and multi-index orthogonal experimental design methods to investigate the seed coating formula and physical properties of Tartary buckwheat. The specific effects of each component on Tartary buckwheat seed germination are analyzed. The findings reveal that the seed coating agent formulated with 1.5% polyvinyl alcohol, 0.15% sodium alginate, 0.2% op-10, 0.1% polyacrylamide, 8% colorant, 3% ammonium sulfate, 1% potassium dihydrogen phosphate, and 0.15% carbendazim exhibits the most effective coating. It demonstrates optimal physical properties and promotes… More >

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