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  • Open Access

    ARTICLE

    Underconstrained Cable-Driven Parallel Suspension System of Virtual Flight Test Model in Wind Tunnel

    Huisong Wu, Kaichun Zeng, Li Yu, Yan Li, Xiping Kou*

    CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.1, pp. 395-416, 2023, DOI:10.32604/cmes.2022.021650

    Abstract An underconstrained cable-driven parallel robot (CDPR) suspension system was designed for a virtual flight testing (VFT) model. This mechanism includes two identical upper and lower kinematic chains, each of which comprises a cylindrical pair, rotating pair, and cable parallelogram. The model is pulled via two cables at the top and bottom and fixed by a yaw turntable, which can realize free coupling and decoupling with three rotational degrees of freedom of the model. First, the underconstrained CDPR suspension system of the VFT model was designed according to the mechanics theory, the degrees of freedom were verified, and the support platform… More >

  • Open Access

    ARTICLE

    Stiffness and Shear Stress Distribution of Glulam Beams in Elastic-Plastic Stage: Theory, Experiments and Numerical Modelling

    Lisheng Luo1,*, Xinran Xie1, Yongqiang Zhang1, Xiaofeng Zhang2, Xinyue Cui1

    Journal of Renewable Materials, Vol.11, No.2, pp. 791-809, 2023, DOI:10.32604/jrm.2022.022539

    Abstract Traditional methods focus on the ultimate bending moment of glulam beams and the fracture failure of materials with defects, which usually depends on empirical parameters. There is no systematic theoretical method to predict the stiffness and shear distribution of glulam beams in elastic-plastic stage, and consequently, the failure of such glulam beams cannot be predicted effectively. To address these issues, an analytical method considering material nonlinearity was proposed for glulam beams, and the calculating equations of deflection and shear stress distribution for different failure modes were established. The proposed method was verified by experiments and numerical models under the corresponding… More > Graphic Abstract

    Stiffness and Shear Stress Distribution of Glulam Beams in Elastic-Plastic Stage: Theory, Experiments and Numerical Modelling

  • Open Access

    ARTICLE

    Detection Collision Flows in SDN Based 5G Using Machine Learning Algorithms

    Aqsa Aqdus1, Rashid Amin1,*, Sadia Ramzan1, Sultan S. Alshamrani2, Abdullah Alshehri3, El-Sayed M. El-kenawy4

    CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 1413-1435, 2023, DOI:10.32604/cmc.2023.031719

    Abstract The rapid advancement of wireless communication is forming a hyper-connected 5G network in which billions of linked devices generate massive amounts of data. The traffic control and data forwarding functions are decoupled in software-defined networking (SDN) and allow the network to be programmable. Each switch in SDN keeps track of forwarding information in a flow table. The SDN switches must search the flow table for the flow rules that match the packets to handle the incoming packets. Due to the obvious vast quantity of data in data centres, the capacity of the flow table restricts the data plane’s forwarding capabilities.… More >

  • Open Access

    ARTICLE

    Improving CNN-BGRU Hybrid Network for Arabic Handwritten Text Recognition

    Sofiene Haboubi1,*, Tawfik Guesmi2, Badr M Alshammari2, Khalid Alqunun2, Ahmed S Alshammari2, Haitham Alsaif2, Hamid Amiri1

    CMC-Computers, Materials & Continua, Vol.73, No.3, pp. 5385-5397, 2022, DOI:10.32604/cmc.2022.029198

    Abstract Handwriting recognition is a challenge that interests many researchers around the world. As an exception, handwritten Arabic script has many objectives that remain to be overcome, given its complex form, their number of forms which exceeds 100 and its cursive nature. Over the past few years, good results have been obtained, but with a high cost of memory and execution time. In this paper we propose to improve the capacity of bidirectional gated recurrent unit (BGRU) to recognize Arabic text. The advantages of using BGRUs is the execution time compared to other methods that can have a high success rate… More >

  • Open Access

    ARTICLE

    Exploration of Waterproofness of Concrete and Alkali-Aggregate Using Hydrophobic Impregnation and Coating

    Shun Kang1, Xun Yuan1, Changwu Liu1,*, Yulin Chen1, Xianliang Zhou1, Haikuan Wu2, Zhiguo Ma3

    Journal of Renewable Materials, Vol.10, No.12, pp. 3521-3538, 2022, DOI:10.32604/jrm.2022.021694

    Abstract Part of the tunnel spoil can not be used for concrete due to alkali-aggregate reaction (AAR). Water is an indispensable condition for AAR, so separating the alkali-aggregate from water is of great benefit to controlling the AAR. This paper investigates the modification of concrete and aggregate by hydrophobic impregnation and organic coating and then evaluates their waterproof and mechanical properties by dynamic contact angle (DCA), ultrasonic wave velocity, scanning electron microscope (SEM), nuclear magnetic resonance (NMR), and so on. For waterproofness, hydrophobic impregnation and organic coating can both improve the waterproofness of concrete and aggregate. The organic coating is suitable… More >

  • Open Access

    ARTICLE

    Profilin 2 Promotes Proliferation and Metastasis of Head and Neck Cancer Cells by Regulating PI3K/AKT/b-Catenin Signaling Pathway

    Kecheng Zhou*†1, Jie Chen*†1, Jiayu Wu*†1, Yangxinzi Xu, Qiaoyun Wu*†, Jingjing Yue*†, Yu Song§, Shengcun Li*†, Peng Zhou, Wenzhan Tu*†, Guanhu Yang*†, Songhe Jiang*†

    Oncology Research, Vol.27, No.9, pp. 1079-1088, 2019, DOI:10.3727/096504019X15579146061957

    Abstract Profilin 2 (PFN2) was found to be mainly expressed in neurons and involved in the development of the brain. In recent years, emerging evidence indicated that PFN2 is also significantly upregulated in various cancers including head and neck cancer (HNSC) and influences cancer cell proliferation, migration, and invasion. However, the role of PFN2 in HNSC development and progression remains unclear. The aim of our study was to investigate the role of PFN2 in the development of HNSC and its possible molecular mechanisms. Bioinformatics showed that increased expression of PFN2 in tumors correlated highly with poor prognosis of HNSC patients. Our… More >

  • Open Access

    ARTICLE

    Human cytomegalovirus autophagy is related to the interferon synthesis and mTOR signal pathway

    DONGMEI GAO1,#, JIAOE CHEN2,#, HONGZHANG LI2,*, JUN ZHAO3,*

    BIOCELL, Vol.46, No.10, pp. 2275-2280, 2022, DOI:10.32604/biocell.2022.021008

    Abstract Introduction: Human cytomegalovirus (HCMV) is reported to be involved in the occurrence of many human diseases. To further investigate the biological changes of HCMV, we analyzed the relevant factors that affect the autophagy caused by HCMV infection. Methods: Firstly, we cultured human embryonic lung fibroblasts (HELF) cells with HCMV infection, and evaluated the effects of HELF cells infected with different viruses through Enzyme-linked immunoabsorbent assay (ELISA), Real-time quantitative Polymerase Chain Reaction (RT-qPCR), Acridine orange (AO) staining and Western blotting (WB) experiments. Results: Through the above experiments, we found that the combined treatment of HCMV infection and carbamazepine, rapamycin and si-mTOR… More >

  • Open Access

    ARTICLE

    False Alarm Reduction in ICU Using Ensemble Classifier Approach

    V. Ravindra Krishna Chandar1,*, M. Thangamani2

    Intelligent Automation & Soft Computing, Vol.34, No.1, pp. 165-181, 2022, DOI:10.32604/iasc.2022.022339

    Abstract

    During patient monitoring, false alert in the Intensive Care Unit (ICU) becomes a major problem. In the category of alarms, pseudo alarms are regarded as having no clinical or therapeutic significance, and thus they result in fatigue alarms. Artifacts are misrepresentations of tissue structures produced by imaging techniques. These Artifacts can invalidate the Arterial Blood Pressure (ABP) signal. Therefore, it is very important to develop algorithms that can detect artifacts. However, ABP has algorithmic shortcomings and limitations of design. This study is aimed at developing a real-time enhancement of independent component analysis (EICA) and time-domain detection of QRS that can… More >

  • Open Access

    ARTICLE

    Computational Investigation of Cell Migration Behavior in a Confluent Epithelial Monolayer

    Jie Bai, Xiaowei Zeng*

    CMES-Computer Modeling in Engineering & Sciences, Vol.131, No.2, pp. 551-565, 2022, DOI:10.32604/cmes.2022.019376

    Abstract Cell migration plays a significant role in many biological activities, yet the physical mechanisms of cell migration are still not well understood. In this study, a continuum physics-based epithelial monolayer model including the intercellular interaction was employed to study the cell migration behavior in a confluent epithelial monolayer at constant cell density. The epithelial cell was modeled as isotropic elastic material. Through finite element simulation, the results revealed that the motile cell was subjected to higher stress than the other jammed cells during the migration process. Cell stiffness was implied to play a significant role in epithelial cell migration behavior.… More >

  • Open Access

    ARTICLE

    Attractive Multistep Reproducing Kernel Approach for Solving Stiffness Differential Systems of Ordinary Differential Equations and Some Error Analysis

    Radwan Abu-Gdairi1, Shatha Hasan2, Shrideh Al-Omari3,*, Mohammad Al-Smadi2,4, Shaher Momani4,5

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.1, pp. 299-313, 2022, DOI:10.32604/cmes.2022.017010

    Abstract In this paper, an efficient multi-step scheme is presented based on reproducing kernel Hilbert space (RKHS) theory for solving ordinary stiff differential systems. The solution methodology depends on reproducing kernel functions to obtain analytic solutions in a uniform form for a rapidly convergent series in the posed Sobolev space. Using the Gram-Schmidt orthogonality process, complete orthogonal essential functions are obtained in a compact field to encompass Fourier series expansion with the help of kernel properties reproduction. Consequently, by applying the standard RKHS method to each subinterval, approximate solutions that converge uniformly to the exact solutions are obtained. For this purpose,… More >

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