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  • Open Access

    REVIEW

    Role of pyroptotic cell death in the pathogenesis of NASH

    Yuguo YI, Jiamin ZHENG, Yang ZHOU, Zhiqin LIU, Dan WENG*

    BIOCELL, Vol.44, No.1, pp. 7-11, 2020, DOI:10.32604/biocell.2020.08686

    Abstract Nonalcoholic fatty liver disease (NAFLD) represents a huge threat to public health of the whole world. Around 25% of NAFLD patients will progress to nonalcoholic steatohepatitis (NASH), which has been predicted to be the main reason for liver transplantation in the United States in 2020. Extensive effort has been devoted to investigating the underlying molecular mechanisms of NASH pathogenesis and developing new promising treatments. Recent studies have demonstrated that pyroptosis, an inflammatory programmed cell death mediated by inflammasome and gasdermin-D (GSDMD), is involved in the development and progression of NASH. This review aims to summarize the recent findings regarding the… More >

  • Open Access

    ARTICLE

    Real-Time Thermomechanical Modeling of PV Cell Fabrication via a POD-Trained RBF Interpolation Network

    Arka Das1, Anthony Khoury1, Eduardo Divo1, *, Victor Huayamave1, Andres Ceballos2, Ron Eaglin2, Alain Kassab3, Adam Payne4, Vijay Yelundur4, Hubert Seigneur5

    CMES-Computer Modeling in Engineering & Sciences, Vol.122, No.3, pp. 757-777, 2020, DOI:10.32604/cmes.2020.08164

    Abstract This paper presents a numerical reduced order model framework to simulate the physics of the thermomechanical processes that occur during c-Si photovoltaic (PV) cell fabrication. A response surface based on a radial basis function (RBF) interpolation network trained by a Proper Orthogonal Decomposition (POD) of the solution fields is developed for fast and accurate approximations of thermal loading conditions on PV cells during the fabrication processes. The outcome is a stand-alone computational tool that provides, in real time, the quantitative and qualitative thermomechanical response as a function of user-controlled input parameters for fabrication processes with the precision of 3D finite… More >

  • Open Access

    ARTICLE

    Green Synthesis of Silver Nanoparticles from Abronia villosa as an Alternative to Control of Pathogenic Microorganisms

    Ali Abdelmoteleb1, Benjamin Valdez-Salas2, Ernesto Beltran-Partida2, Daniel Gonzalez-Mendoza3,*

    Journal of Renewable Materials, Vol.8, No.1, pp. 69-78, 2020, DOI:10.32604/jrm.2020.08334

    Abstract The aim of this study was to evaluate the antibacterial and antifungal activities of eco-friendly synthesized silver nanoparticles. The silver nanoparticles were synthesized by biological method using aqueous extract of Abronia villosa. Synthesis of silver nanoparticles was confirmed by color change and characterized using UV-visible spectroscopy, scanning electron microscope (SEM), energy dispersive X-ray spectroscopy (EDX), dynamic light scattering (DLS), and zeta potential analysis. The SEM analysis revealed the presence of spherical silver nanoparticles of the size range 21 to 33 nm. Synthesized silver nanoparticles were used to evaluate their antibacterial effects at different concentrations (25, 50, 75 and 100 µg/ml)… More >

  • Open Access

    ARTICLE

    Polymer-based encapsulation of Bacillus subtilis and its effect on Meloidogyne incognita in tomato

    Pacheco-Aguirre J, E Ruiz-Sánchez, A Reyes-Ramírez, J Cristóbal-Alejo, J Tun-Suárez, L Borges-Gómez

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 1-6, 2016, DOI:10.32604/phyton.2016.85.001

    Abstract Antagonistic bacteria used as biological control agent may loss effectiveness at the field due to environmental factors such as UV radiation, dryness and high temperature. An inexpensive alternative to protect antagonistic bacteria against such factors is the use of microencapsulating agents. In this work, the effect of microencapsulation of Bacillus subtilis with commercial gums on their antagonistic capacity against Meloidogyne incognita was evaluated. The efficiency of the microencapsulation was verified by the difference between the initial and final concentrations of protein release. The effectiveness as antagonist was evaluated against M. incognita in tomato under greenhouse conditions. The microcapsules based on… More >

  • Open Access

    ARTICLE

    Brief note: Differences in intracellular localization of corn stunt spiroplasmas in magnesium treated maize.

    CLAUDIA NOME1*, PAULO CÉSAR MAGALHÃES2, ELIZABETH OLIVEIRA2, SERGIO NOME, IRMA GRACIELA LAGUNA1

    BIOCELL, Vol.33, No.2, pp. 133-136, 2009, DOI:10.32604/biocell.2009.33.133

    Abstract Maize plants infected with Spiroplasma kunkelii show symptoms similar to that of plants in a magnesium-deficient soil, and it has been shown that the spiroplasma alters the plants’ magnesium absorption. In the current study we compared changes associated to either spiroplasma infection, two soil magnesium levels and their combinations. Plant symptoms were recorded and correlated with transmission electron microscopy observations. Plants grown on a high magnesium treatment showed no macroscopical alterations nor organelle ultrastructural alterations, while plants on a low magnesium treatment showed macroscopical vein yellowing and, ultrastructurally, they had most chloroplasts and mitochondrial membranes altered. Infected plants on a… More >

  • Open Access

    ARTICLE

    Apoptosis as pathogenic mechanism of infection with vesicular stomatitis virus. Evidence in primary bovine fibroblast cultures

    A. LÓPEZ-HERRERA1*, J. RUIZ-SÁENZ2, Y.P. GÓEZ3, W. ZAPATA3, P.A. VELILLA3, A.E. ARANGO3, S. URCUQUI-INCHIMA3

    BIOCELL, Vol.33, No.2, pp. 121-132, 2009, DOI:10.32604/biocell.2009.33.121

    Abstract To determine whether fibroblasts from Blanco Orejinegro cattle, exhibit any level of resistance to infection against vesicular stomatitis virus (VSV) serotypes Indiana (VSV-I) or New Jersey (VSVNJ), 30 fibroblast cultures were phenotyped to evaluate their resistance/susceptibility. Thirty three % of Blanco Orejinegro fibroblast cultures were classified as very resistant, 50% as resistant, and 17% as susceptible to VSV-I infection, whereas 20% were classified as very resistant, 50% as resistant and 30% as susceptible to VSV-NJ infection. Therefore, there appears to be a large variation in phenotypic polymorphism among the fibroblasts to infection by VSV. To elucidate the mechanisms responsible for… More >

  • Open Access

    ARTICLE

    Sequential expressions of Notch1, Jagged2 and Math1 in molar tooth germ of mouse

    SILVIA S. BORKOSKY1,2, HITOSHI NAGATSUKA1, YORIHISA ORITA3, HIDETSUGU TSUJIGIWA4, JUNKO YOSHINOBU3, MEHMET GUNDUZ1, ANDREA P. RODRIGUEZ1, LILIANA R. MISSANA2, KAZUNORI NISHIZAKI3, NORIYUKI NAGAI1

    BIOCELL, Vol.32, No.3, pp. 251-257, 2008, DOI:10.32604/biocell.2008.32.251

    Abstract The Notch signaling pathway is an evolutionary conserved mechanism that plays an important role in cell-cell communication and cell fate in a wide range of tissues. The mammalian family of Notch receptors consists of 4 members: Notch1/2/3/4. The Notch ligand family consists of 5 members: Delta1/3/4 and Jagged1/2. Math1 encodes a murine basic helix-loop-helix (bHLH) transcription factor that acts as positive regulator of cell differentiation. Recently, links between Notch and Math1 pathways were demonstrated in various tissues. Expression of Notch1, Jagged2 and Math1 were analyzed in the mouse molar tooth germ during embryonic stage (E) 13 and E15 and during… More >

  • Open Access

    ARTICLE

    Differentiation and morphogenesis of Triatoma infestans (Klug 1834) female gonads. I – Post embryonic development

    CECILIA I. IBAÑEZ DE BARRETT, JUAN PABLO BOZZINI, MARTA MARIANO DE BOZZINI*

    BIOCELL, Vol.28, No.3, pp. 259-269, 2004, DOI:10.32604/biocell.2004.28.259

    Abstract The post-embryonic development of the female gonads in Triatoma infestans (Hemiptera, Heteroptera), insects of importance in health affairs as harbors and vectors of different tripanosomatidea flagellates, is presented in a complete follow-up since insect hatches from the egg up to the last molt in the fifth instar stage. The detailed description of the morphological changes which occur in each instar as well as careful measurements evaluating its size increase have been analyzed by stereomicroscopy, phase contrast, dark field, and oblique illumination, in order to optimize the observations as well the photographic register of gonad morphology and structure.
    The analysis… More >

  • Open Access

    ARTICLE

    Antimicrobial evaluation of extracts obtained from tropical micromycetes against phytopathogens

    Moreno Pérez P1,3, M Gamboa Angulo1, G Heredia2, B Canto Canché1, CM Rodríguez García1, IL Medina Baizabal1, L Peraza Echeverría1

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 7-14, 2016, DOI:10.32604/phyton.2016.85.007

    Abstract Nowadays, it is highly necessary to find more and safer agrochemicals. In this sense, micromycetes are an important source of natural products which could be used to control plant diseases. Therefore with the aims to contribute in this searching of natural products with antimicrobial applications, a total of 49 fungal strains were isolated from the Yucatan Peninsula. These fungi were cultured in fermented rice, their respective organic extracts macerated in ethyl acetate (EAE) and methanol (ME) were obtained and tested against five fungal pathogens of agricultural importance. These included Alternaria chrysanthemi, Colletotrichum gloeosporioides, Mycosphaerella fijiensis, and the bacteria Erwinia carotovoraMore >

  • Open Access

    ARTICLE

    First morphogenetic identification of Fusarium solani isolated from orange fruit in Egypt

    Abd-Elsalam KA1,2, K Youssef1,2, H Almoammar3

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 128-131, 2015, DOI:10.32604/phyton.2015.84.128

    Abstract Losses due to postharvest decay may occur at any time during postharvest handling, from harvest to consumption affecting the produce quality and quantity. Accurate identification of the pathogen causing postharvest disease is essential to the selection of an appropriate disease control approach. Nine isolates of Fusarium recovered from orange fruit were identified as Fusarium solani. The fungus is involved with fruit decay. The obtained cultures were purified and grown on potato-dextrose agar (PDA), malt yeast agar (MYA), and Czapek's nutrient media (CNM) under light for identification. A pathogenicity test was carried out to fulfil Koch's postulates. The pathogen could only… More >

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