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  • Open Access

    ARTICLE

    CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma

    SHUANGSHUANG ZENG1,2, XI CHEN1,2, QIAOLI YI1,2, ABHIMANYU THAKUR3, HUI YANG4,*, YUANLIANG YAN1,2, SHAO LIU1,2,*

    Oncology Research, Vol.32, No.2, pp. 261-272, 2024, DOI:10.32604/or.2023.042345

    Abstract Finding biomarkers for immunotherapy is an urgent issue in cancer treatment. Cellular retinoic acid-binding protein 2 (CRABP2) is a controversial factor in the occurrence and development of human tumors. However, there is limited research on the relationship between CRABP2 and immunotherapy response. This study found that negative correlations of CRABP2 and immune checkpoint markers (PD-1, PD-L1, and CTLA-4) were observed in breast invasive carcinoma (BRCA), skin cutaneous melanoma (SKCM), stomach adenocarcinoma (STAD) and testicular germ cell tumors (TGCT). In particular, in SKCM patients who were treated with PD-1 inhibitors, high levels of CRABP2 predicted poor prognosis. Additionally, CRABP2 expression was… More >

  • Open Access

    ARTICLE

    Learning Dual-Domain Calibration and Distance-Driven Correlation Filter: A Probabilistic Perspective for UAV Tracking

    Taiyu Yan1, Yuxin Cao1, Guoxia Xu1, Xiaoran Zhao2, Hu Zhu1, Lizhen Deng3,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3741-3764, 2023, DOI:10.32604/cmc.2023.039828

    Abstract Unmanned Aerial Vehicle (UAV) tracking has been possible because of the growth of intelligent information technology in smart cities, making it simple to gather data at any time by dynamically monitoring events, people, the environment, and other aspects in the city. The traditional filter creates a model to address the boundary effect and time filter degradation issues in UAV tracking operations. But these methods ignore the loss of data integrity terms since they are overly dependent on numerous explicit previous regularization terms. In light of the aforementioned issues, this work suggests a dual-domain Jensen-Shannon divergence correlation filter (DJSCF) model address… More >

  • Open Access

    ARTICLE

    Optical Fibre Communication Feature Analysis and Small Sample Fault Diagnosis Based on VMD-FE and Fuzzy Clustering

    Xiangqun Li1,*, Jiawen Liang2, Jinyu Zhu2, Shengping Shi2, Fangyu Ding2, Jianpeng Sun2, Bo Liu2

    Energy Engineering, Vol.121, No.1, pp. 203-219, 2024, DOI:10.32604/ee.2023.029295

    Abstract To solve the problems of a few optical fibre line fault samples and the inefficiency of manual communication optical fibre fault diagnosis, this paper proposes a communication optical fibre fault diagnosis model based on variational modal decomposition (VMD), fuzzy entropy (FE) and fuzzy clustering (FC). Firstly, based on the OTDR curve data collected in the field, VMD is used to extract the different modal components (IMF) of the original signal and calculate the fuzzy entropy (FE) values of different components to characterize the subtle differences between them. The fuzzy entropy of each curve is used as the feature vector, which… More >

  • Open Access

    ARTICLE

    Development and Application of a Power Law Constitutive Model for Eddy Current Dampers

    Longteng Liang1,2,3, Zhouquan Feng2,4,*, Hongyi Zhang2,4, Zhengqing Chen2,4, Changzhao Qian1,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2403-2419, 2024, DOI:10.32604/cmes.2023.031260

    Abstract Eddy current dampers (ECDs) have emerged as highly desirable solutions for vibration control due to their exceptional damping performance and durability. However, the existing constitutive models present challenges to the widespread implementation of ECD technology, and there is limited availability of finite element analysis (FEA) software capable of accurately modeling the behavior of ECDs. This study addresses these issues by developing a new constitutive model that is both easily understandable and user-friendly for FEA software. By utilizing numerical results obtained from electromagnetic FEA, a novel power law constitutive model is proposed to capture the nonlinear behavior of ECDs. The effectiveness… More >

  • Open Access

    ARTICLE

    Fault Identification for Shear-Type Structures Using Low-Frequency Vibration Modes

    Cuihong Li1, Qiuwei Yang2,3,*, Xi Peng2,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2769-2791, 2024, DOI:10.32604/cmes.2023.030908

    Abstract Shear-type structures are common structural forms in industrial and civil buildings, such as concrete and steel frame structures. Fault diagnosis of shear-type structures is an important topic to ensure the normal use of structures. The main drawback of existing damage assessment methods is that they require accurate structural finite element models for damage assessment. However, for many shear-type structures, it is difficult to obtain accurate FEM. In order to avoid finite element modeling, a model-free method for diagnosing shear structure defects is developed in this paper. This method only needs to measure a few low-order vibration modes of the structure.… More >

  • Open Access

    ARTICLE

    Prediction of Damping Capacity Demand in Seismic Base Isolators via Machine Learning

    Ayla Ocak1, Ümit Işıkdağ2, Gebrail Bekdaş1,*, Sinan Melih Nigdeli1, Sanghun Kim3, Zong Woo Geem4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2899-2924, 2024, DOI:10.32604/cmes.2023.030418

    Abstract Base isolators used in buildings provide both a good acceleration reduction and structural vibration control structures. The base isolators may lose their damping capacity over time due to environmental or dynamic effects. This deterioration of them requires the determination of the maintenance and repair needs and is important for the long-term isolator life. In this study, an artificial intelligence prediction model has been developed to determine the damage and maintenance-repair requirements of isolators as a result of environmental effects and dynamic factors over time. With the developed model, the required damping capacity of the isolator structure was estimated and compared… More >

  • Open Access

    ARTICLE

    Tool Wear State Recognition with Deep Transfer Learning Based on Spindle Vibration for Milling Process

    Qixin Lan1, Binqiang Chen1,*, Bin Yao1, Wangpeng He2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.3, pp. 2825-2844, 2024, DOI:10.32604/cmes.2023.030378

    Abstract The wear of metal cutting tools will progressively rise as the cutting time goes on. Wearing heavily on the tool will generate significant noise and vibration, negatively impacting the accuracy of the forming and the surface integrity of the workpiece. Hence, during the cutting process, it is imperative to continually monitor the tool wear state and promptly replace any heavily worn tools to guarantee the quality of the cutting. The conventional tool wear monitoring models, which are based on machine learning, are specifically built for the intended cutting conditions. However, these models require retraining when the cutting conditions undergo any… More >

  • Open Access

    ARTICLE

    Study of Axial Vibration of a Motor-Compressor System Using Operational Modal Analysis

    M. Farid Yahya1, Reduan Mat Dan2,3,*, M. Fadzlee Samsubaha1, Zaini Rashid1, Azma Putra2,3,*

    Sound & Vibration, Vol.57, pp. 119-131, 2023, DOI:10.32604/sv.2023.045029

    Abstract A case study of excessive vibration on a motor-compressor system is presented in this paper. After barely two months of operation, the reciprocating compressor motor’s routine monitoring revealed excessive axial vibration amplitude. For this reason, the Operational Modal Analysis (OMA) was carried out in order to identify the primary cause. According to the investigation, one of the harmonic components which was 18 times the motor’s running speed matched with a resonance frequency of 112 Hz. According to OMA study, the motor was vibrating in torsional motion because the compressor’s load had stimulated the entire motor-compressor unit at this resonance frequency.… More >

  • Open Access

    ARTICLE

    Influence of Trailing-Edge Wear on the Vibrational Behavior of Wind Turbine Blades

    Yuanjun Dai1,2,*, Xin Wei1, Baohua Li1, Cong Wang1, Kunju Shi1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.2, pp. 337-348, 2024, DOI:10.32604/fdmp.2023.042434

    Abstract To study the impact of the trailing-edge wear on the vibrational behavior of wind-turbine blades, unworn blades and trailing-edge worn blades have been assessed through relevant modal tests. According to these experiments, the natural frequencies of trailing-edge worn blades −1, −2, and −3 increase the most in the second to fourth order, the fifth order increases in the middle, and the first order increases the least. The damping ratio data indicate that, in general, the first five-order damping ratios of trailing-edge worn blades −1 and trailing-edge worn blades −2 are reduced, and the first five-order damping ratios of trailing-edge worn… More >

  • Open Access

    ARTICLE

    Research on Stick-Slip Vibration Suppression Method of Drill String Based on Machine Learning Optimization

    Kanhua Su, Jian Wei*, Meng Li, Hao Li, Wenghao Da, Lang Zhang

    Sound & Vibration, Vol.57, pp. 97-117, 2023, DOI:10.32604/sv.2023.043734

    Abstract During the drilling process, stick-slip vibration of the drill string is mainly caused by the nonlinear friction generated by the contact between the drill bit and the rock. To eliminate the fatigue wear of downhole drilling tools caused by stick-slip vibrations, the Fractional-Order Proportional-Integral-Derivative (FOPID) controller is used to suppress stick-slip vibrations in the drill string. Although the FOPID controller can effectively suppress the drill string stick-slip vibration, its structure is flexible and parameter setting is complicated, so it needs to use the corresponding machine learning algorithm for parameter optimization. Based on the principle of torsional vibration, a simplified model… More > Graphic Abstract

    Research on Stick-Slip Vibration Suppression Method of Drill String Based on Machine Learning Optimization

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