V. Priya¹, I. Sumaiya Thaseen¹, Thippa Reddy Gadekallu¹, Mohamed K. Aboudaif^2,*, Emad Abouel Nasr³

CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 2457-2470, 2021, DOI:10.32604/cmc.2021.013852

Abstract Generally, the risks associated with malicious threats are increasing for the Internet of Things (IoT) and its related applications due to dependency on the Internet and the minimal resource availability of IoT devices. Thus, anomaly-based intrusion detection models for IoT networks are vital. Distinct detection methodologies need to be developed for the Industrial Internet of Things (IIoT) network as threat detection is a significant expectation of stakeholders. Machine learning approaches are considered to be evolving techniques that learn with experience, and such approaches have resulted in superior performance in various applications, such as pattern recognition, outlier analysis, and speech recognition.… More >

XIAOLIN ZHU^1,3, XIAOHONG WEI^1,3,*, BAOQIANG WANG^2,3, XIAN WANG², MINGJUN ZHANG⁴

BIOCELL, Vol.44, No.4, pp. 777-803, 2020, DOI:10.32604/biocell.2020.010153

Abstract AP2/ERE-type transcription factors, as a type of plant-specific transcription factors, play a key role in plant biotic and abiotic stress. Meanwhile, they have been studied in many plants, but rarely in tomatoes. In this study, we performed a genome-wide analysis of the SlAP2/ERF gene family of tomato, and finally identified 29 SlAP2/ERF genes and divided them into different subfamilies. At the same time, its basic physical and chemical properties were analyzed. We also constructed phylogenetic trees with 30 Arabidopsis AP2/ERF proteins and 28 potatoes AP2/ERF proteins to ensure conservative homology between them. In addition, we mapped 29 SlAP2/ERF transcription factors… More >

YUE CHEN¹, ZHITING TANG², MIAO YU¹, RUI ZHANG^1,*, XINXIN DONG¹, LIANQUN CAO¹

BIOCELL, Vol.44, No.4, pp. 513-524, 2020, DOI:10.32604/biocell.2020.09422

Abstract Preoperative chemoradiation therapy (CRT) is becoming the standard treatment for patients with locally advanced rectal cancer. However, individual differences in response to treatment range from a complete response to complete resistance. Predicting the tumor response to radiotherapy may improve the efficacy of radiotherapy. This review mainly summarizes recent studies about the molecular biomarkers that can predict the response to radiotherapy in rectal cancer. These studies have indicated that the molecular markers involved in the response to radiotherapy mainly include genes related to radiosensitivity, cancer stem cell-related markers, non-coding RNAs (ncRNAs), single-nucleotide polymorphisms (SNPs) and gene methylation, and other factors including… More >

Pingshui Wang^1,2,*, Willy Susilo²

Computer Systems Science and Engineering, Vol.36, No.1, pp. 213-224, 2021, DOI:10.32604/csse.2021.014541

Abstract With the development of information technology, the Internet of Things (IoT) has gradually become the third wave of the worldwide information industry revolution after the computer and the Internet. The application of the IoT has brought great convenience to people’s production and life. However, the potential information security problems in various IoT applications are gradually exposed and people pay more attention to them. The traditional centralized data storage and management model of the IoT is easy to cause transmission delay, single point of failure, privacy disclosure and other problems, and eventually leads to unpredictable behavior of the system. Blockchain technology… More >

Ahmad F. Subahi^*

Computer Systems Science and Engineering, Vol.36, No.1, pp. 13-39, 2021, DOI:10.32604/csse.2021.014376

Abstract This work presents the design of an Internet of Things (IoT) edge-based system based on model transformation and complete weighted graph to detect violations of social distancing measures in indoor public places. A wireless sensor network based on Bluetooth Low Energy is introduced as the infrastructure of the proposed design. A hybrid model transformation strategy for generating a graph database to represent groups of people is presented as a core middleware layer of the detecting system’s proposed architectural design. A Neo4j graph database is used as a target implementation generated from the proposed transformational system to store all captured real-time… More >

Majid Monajjemi^1,*, Rahim Esmkhani², Fatemeh Mollaamin¹, Sara Shahriari³

CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.3, pp. 907-926, 2020, DOI:10.32604/cmes.2020.012846

Abstract Current understanding about how the virus that causes COVID-19 spreads is largely based on what is known about similar coronaviruses. Some of the Natural products are suitable drugs against SARS-CoV-2 main protease. For recognizing a strong inhibitor, we have accomplished docking studies on the major virus protease with 4 natural product species as anti COVID-19 (SARS-CoV-2), namely “Vidarabine”, “Cytarabine”, “Gemcitabine” and “Matrine” which have been extracted from Gillan’s leaves plants. These are known as Chuchaq, Trshvash, Cote-Couto and Khlvash in Iran. Among these four studied compounds, Cytarabine appears as a suitable compound with high effectiveness inhibitors to this protease. Finally… More >

Vankamamidi S. Naresh^1,∗,†, Suryateja S. Pericherla^2,‡, Pilla Sita Rama Murty^3,§, Sivaranjani Reddi^4,¶

Computer Systems Science and Engineering, Vol.35, No.6, pp. 411-421, 2020, DOI:10.32604/csse.2020.35.411

Abstract Healthcare, the largest global industry, is undergoing significant transformations with the genesis of a new technology known as the Internet of Things (IoT). Many healthcare leaders are investing more money for transforming their services to harness the benefits provided by IoT, thereby paving the way for the Internet of Medical Things (IoMT), an extensive collection of medical sensors and associated infrastructure. IoMT has many benefits like providing remote healthcare by monitoring health vitals of patients at a distant place, providing healthcare services to elderly people, and monitoring a large group of people in a region or country for detection and… More >

Ali Saadon Al-Ogaili^1,*, Ameer Alhasan², Agileswari Ramasamy¹, Marayati Binti Marsadek¹, Tengku Juhana Tengku Hashim¹, Ammar Al-Sharaa³, Mastura Binti Aadam³, Lukman Audah²

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 2141-2164, 2021, DOI:10.32604/cmc.2020.013440

Abstract The Coronavirus (COVID-19) pandemic is considered as a global public health challenge. To contain this pandemic, different measures are being taken globally. The Internet of Things (IoT) has been represented as one of the most important schemes that has been considered to fight the spread of COVID-19 in the world, practically Malaysia. In fact, there are many sectors in Malaysia would be transformed into smart services by using IoT technologies, particularly energy, transportation, healthcare sectors. This manuscript presents a comprehensive review of the IoT technologies that are being used currently in Malaysia to accelerate the measures against COVID-19. These IoT… More >

K. Shankar^1,*, Eswaran Perumal¹, Mohamed Elhoseny², Phong Thanh Nguyen³

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1665-1680, 2021, DOI:10.32604/cmc.2020.013251

Abstract Diabetic retinopathy (DR) is a disease with an increasing prevalence and the major reason for blindness among working-age population. The possibility of severe vision loss can be extensively reduced by timely diagnosis and treatment. An automated screening for DR has been identified as an effective method for early DR detection, which can decrease the workload associated to manual grading as well as save diagnosis costs and time. Several studies have been carried out to develop automated detection and classification models for DR. This paper presents a new IoT and cloud-based deep learning for healthcare diagnosis of Diabetic Retinopathy (DR). The… More >

Deepak Prashar¹, Gyanendra Prasad Joshi², Sudan Jha¹, Eunmok Yang³, Kwang Chul Son^4,*

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 1529-1549, 2021, DOI:10.32604/cmc.2020.012986

Abstract The Internet of Things (IoT) is envisioned as a network of various wireless sensor nodes communicating with each other to offer state-of-the-art solutions to real-time problems. These networks of wireless sensors monitor the physical environment and report the collected data to the base station, allowing for smarter decisions. Localization in wireless sensor networks is to localize a sensor node in a two-dimensional plane. However, in some application areas, such as various surveillances, underwater monitoring systems, and various environmental monitoring applications, wireless sensors are deployed in a three-dimensional plane. Recently, localization-based applications have emerged as one of the most promising services… More >