Rongge Xiao^a , Yue Zhu^b,*, Wenbo Jin^a , Zheng Dai^a , Shifang Li^a , Fan Zhang^c

Frontiers in Heat and Mass Transfer, Vol.12, pp. 1-6, 2019, DOI:10.5098/hmt.12.28

Abstract In order to accurately obtain the wax deposition rate model, according to the kinetic principle of wax deposition, several factors affecting the wax deposition rate were selected, and by a optimization software of First Optimization(1stOpt), The parameters of two typical wax deposition rate models are solved respectively based on optimization algorithm combined by Levenberg-Marquardt (L-M) algorithm and global optimization and the calculated data were compared. The results show that: compared with the model parameters obtained by least squares method, the model parameters obtained by this optimization algorithm can describe the variation of wax deposition rate… More >

Juanjuan Yao^*, Liang Zhong^†, Pengqiang Zhong^*, Dongdong Liu^†, Zhen Yuan^†, Junmei Liu^*, Shifei Yao^*, Yi Zhao^*, Min Chen^*, Lianwen Li^*, Lu Liu^†, Beizhong Liu^*†

Oncology Research, Vol.27, No.7, pp. 809-818, 2019, DOI:10.3727/096504018X15451301487729

Abstract RAS-responsive element-binding protein 1 (RREB1) is a transcription factor that is implicated in RAS signaling and multiple tumors. However, the role of RREB1 in acute myeloid leukemia has not been studied. We found that RREB1 is overexpressed in AML patients and myeloid leukemia cell lines (NB4 and HL-60), and RREB1 expression was significantly decreased during granulocytic differentiation of myeloid leukemia cells induced by all-trans retinoic acid (ATRA). Then we performed a RREB1 knockdown assay in NB4 and HL-60 cells; the results showed that knockdown of RREB1 upregulated expression of CD11b, CEBP , and microRNA-145 (miR-145), More >

Juan Li

Intelligent Automation & Soft Computing, Vol.25, No.1, pp. 35-48, 2019, DOI:10.31209/2018.100000003

Abstract K-Nearest Neighbor algorithm (KNN) is a simple and mature classification method. However there are susceptible factors influencing the classification performance, such as k value determination, the overlarge search space, unbalanced and multi-class patterns, etc. To deal with the above problems, a new classification algorithm that absorbs tree structure, tree pruning and adaptive k value method was proposed. The proposed algorithm can overcome the shortcoming of KNN, improve the performance of multi-class and unbalanced classification, reduce the scale of dataset maintaining the comparable classification accuracy. The simulations are conducted and the proposed algorithm is compared with several existing More >

Jun Oyamada¹, Chisato Shimizu¹, Jihoon Kim², Matthew R. Williams^1,3, Eileen Png⁴, Martin L. Hibberd⁴, Adriana H. Tremoulet^1,3, James C. Perry^1,3, Jane C. Burns^1,3

Congenital Heart Disease, Vol.14, No.2, pp. 213-220, 2019, DOI:10.1111/chd.12696

Abstract Background: We previously described the association of genetic variants in calcium channel genes and susceptibility to Kawasaki disease (KD), an acute, self‐limited vas‐ culitis, and the most common cause of acquired cardiac disease in children. Abnormal repolarization of cardiomyocytes and changes in T wave morphology have been re‐ ported in KD but have not been studied systematically.
Methods: We analyzed acute and convalescent ECG T wave morphology in two inde‐ pendent cohorts of KD subjects and studied the association between bifid T waves and genetic variants in previously reported genes with SNVs associated with cardiac repolarization.
Results: Bifid… More >

Morgan Chabannes^1,2,*, Frédéric Becquart^1,2, Nor-Edine Abriak^1,2

Journal of Renewable Materials, Vol.7, No.9, pp. 855-863, 2019, DOI:10.32604/jrm.2019.06779

Abstract The return to old building methods by mixing crop by-products with mineral binders is arousing great interest in Europe since about 25 years. The use of these bio-aggregates based materials for the design of building envelopes is a valuable opportunity to deal with increasingly demanding thermal regulations. In addition, the regulatory framework is moving towards reducing the overall car-bon footprint of new buildings. Some traditional and historic buildings are based on timber framing with earth-straw as infill material for instance. Hemp concrete is a bio-based material that can be manually tamped in timber stud walls… More >

Yirong Jiang¹, Weijin Jiang^2,3,4,*, Jiahui Chen^2,*, Yang Wang², Yuhui Xu², Lina Tan², Liang Guo⁵

Journal on Internet of Things, Vol.1, No.2, pp. 41-53, 2019, DOI:10.32604/jiot.2019.07231

Abstract The symbolic network adds the emotional information of the relationship, that is, the “+” and “-” information of the edge, which greatly enhances the modeling ability and has wide application in many fields. Weak unbalance is an important indicator to measure the network tension. This paper starts from the weak structural equilibrium theorem, and integrates the work of predecessors, and proposes the weak unbalanced algorithm EAWSB based on evolutionary algorithm. Experiments on the large symbolic networks Epinions, Slashdot and WikiElections show the effectiveness and efficiency of the proposed method. In EAWSB, this paper proposes a More >

Deng Li¹, Shuwei Chang^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.120, No.2, pp. 305-318, 2019, DOI:10.32604/cmes.2019.06475

Abstract Mechanical force plays a critical role in the remodeling and degradation of cartilage tissues. The cartilage tissue generates, absorbs, and transmits mechanical force, enabling specific biological processes in our body. A moderate intensity mechanical force is necessary for cartilage tissue remodeling and the adaptation of biomechanical properties, but a high intensity mechanical force can lead to pathological degradation of cartilage tissue. However, the molecular mechanism of cartilage degradation is still unclear. We use full atomistic simulations with SMD simulations to investigate whether the magnitude of mechanical force affects the unbinding pathway of the MMP8-Aggrecan_IGD complex. More >

Kamaljit Kaur^{1, *}, Kuljit Kaur²

CMC-Computers, Materials & Continua, Vol.60, No.3, pp. 913-946, 2019, DOI:10.32604/cmc.2019.07675

Abstract Hard Disk drives (HDDs) are an essential component of cloud computing and big data, responsible for storing humongous volumes of collected data. However, HDD failures pose a huge challenge to big data servers and cloud service providers. Every year, about 10% disk drives used in servers crash at least twice, lead to data loss, recovery cost and lower reliability. Recently, the researchers have used SMART parameters to develop various prediction techniques, however, these methods need to be improved for reliability and real-world usage due to the following factors: they lack the ability to consider the More >

Jerry G. Blaivas, Jeffrey P. Weiss

Canadian Journal of Urology, Vol.25, No.1, pp. 9152-9153, 2018

Abstract This article has no abstract. More >

Taha A. Abdel-Meguid^1,2, Hisham A. Mosli¹, Hasan Farsi¹, Ahmad Alsayyad¹, Abdulmalik Tayib¹, Moataz Sait¹, Ahmad Abdelsalam^1,3

Canadian Journal of Urology, Vol.25, No.2, pp. 9273-9280, 2018

Abstract Introduction: To evaluate the efficacy and safety of intraprostatic injections of onabotulinumtoxinA (onaBoNT-A) to treat refractory chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Materials and methods: Prospective two-group controlled study. Treatment group included adult men with refractory category-III nonbacterial CP/CPPS who underwent transurethral intraprostatic injections of onaBoNT-A (200 U). Control group included comparable patients who underwent cystoscopy only. Primary outcome was the proportion of 6-point responders (≥ 6 points reduction of total score of National Institutes of Health-Chronic Prostatitis Symptom Index [NIH-CPSI]) at 3 months. Secondary outcomes included proportions of quality of life (QoL) responders (≤ 2 points… More >