Adel Assiri^*

CMC-Computers, Materials & Continua, Vol.66, No.1, pp. 767-778, 2021, DOI:10.32604/cmc.2020.013813 - 30 October 2020

Abstract Anomaly classification based on network traffic features is an important task to monitor and detect network intrusion attacks. Network-based intrusion detection systems (NIDSs) using machine learning (ML) methods are effective tools for protecting network infrastructures and services from unpredictable and unseen attacks. Among several ML methods, random forest (RF) is a robust method that can be used in ML-based network intrusion detection solutions. However, the minimum number of instances for each split and the number of trees in the forest are two key parameters of RF that can affect classification accuracy. Therefore, optimal parameter selection… More >

D. MURALI MANOHAR^1,*, B.C. CHAKRABORTY², S. SHAMSHATH BEGUM³

Journal of Polymer Materials, Vol.37, No.1-2, pp. 91-107, 2020, DOI:10.32381/JPM.2020.37.1-2.7

Abstract In search of improved materials for efficient shock and vibration mounts for machineries, graphite loaded NBR and NBR/PVC blend were made and investigated. The scorch time was seen to be reduced and vulcanization rate was enhanced due to graphite inclusion. Scanning electron microscopy images have shown homogenous dispersion of graphite powder. NBRgraphite showed a gradual increase in the hardness, tensile strength, Young’s modulus, and tear values with increasing graphite loading. In the case of NBR/PVC-graphite composition, a drop in the tensile strength and increase in the Young’ modulus and tear strength was observed. Various mathematical More >

Xiao-Na L^*i, Hong Yang^†, Tao Yang^‡

Oncology Research, Vol.28, No.1, pp. 41-49, 2020, DOI:10.3727/096504019X15615433287579

Abstract In the present study, we investigated the role of miR-122 in hepatocarcinoma progression and explored the mechanism. In hepatocarcinoma tissues and cells, we used qRT-PCR to validate the miR-122 expression level. Next, we used colony formation by crystal violet staining assay to compare cell proliferation ability, and we used scratch test or Transwell assay to compare cell migration or invasion ability. We then conducted bioinformatics or luciferase reporter gene assay to prove the regulation effect of miR-122 on lamin B2 (LMNB2), and the biological function of LMNB2 was analyzed. We used nude mouse tumorigenicity assay… More >

Leonard Lothstein^*, Judith Soberman^†, Deanna Parke^*, Jatin Gandhi^*, Trevor Sweatman^‡, Tiffany Seagroves^*

Oncology Research, Vol.28, No.5, pp. 451-465, 2020, DOI:10.3727/096504020X15898794315356

Abstract Triple-negative breast cancer (TNBC) is unresponsive to antiestrogen and anti-HER2 therapies, requiring the use of cytotoxic drug combinations of anthracyclines, taxanes, cyclophosphamide, and platinum compounds. Multidrug therapies achieve pathological cure rates of only 20–40%, a consequence of drug resistance and cumulative dose limitations necessitated by the reversible cardiotoxic effects of drug therapy. Safer and more effective treatments for TNBC are required to achieve durable therapeutic responses. This study describes the mechanistic analyses of the novel anthracycline, pivarubicin, and its in vivo efficacy against human primary TNBC. Pivarubicin directly activates PKCd, triggers rapid mitochondrial-dependent apoptosis, and… More >

Chunmou Li^*1, Xiaomin Peng^*1, Chuchu Feng^*1, Xilin Xiong^*, Jianxin Li^†, Ning Liao^‡, Zhen Yang^§, Aiguo Liu^¶, Pingping Wu^*, Xuehong Liang^†, Yunyan He^‡, Xin Tian^§, Yunbi Lin^§, Songmi Wang^¶, Yang Li^*

Oncology Research, Vol.28, No.7-8, pp. 791-800, 2020, DOI:10.3727/096504021X16184815905096

Abstract This nonrandomized, multicenter cohort, open-label clinical trial evaluated the efficacy and safety of combined chemotherapy with arsenic trioxide (ATO) in children with stage 4/M neuroblastoma (NB). We enrolled patients who were newly diagnosed with NB and assessed as stage 4/M and received either traditional chemotherapy or ATO combined with chemotherapy according to their own wishes. Twenty-two patients were enrolled in the trial group (ATO combined with chemotherapy), and 13 patients were enrolled in the control group (traditional chemotherapy). Objective response rate (ORR) at 4 weeks after completing induction chemotherapy was defined as the main outcome,… More >

Jiana Chen¹, Ruichun Zhang², Fangbo Cao¹, Xiaohong Yin^1,3, Tianfeng Liang³, Min Huang^1,*, Yingbin Zou¹

Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 1043-1057, 2020, DOI:10.32604/phyton.2020.011361 - 09 November 2020

Abstract Double-season rice cropping systems occupy a large portion of the rice production area in southern China. Because the problem of insufficient labor, mechanical transplanting (in contrast to the manual transplanting) was become more attractive in double-season rice system. However, the decisive yield factors which resulting in high grain yield of early-season rice are unclear under mechanical-transplanted conditions. In present study, the field experiments were conducted in the early season in 2017 and repeated in 2018 in Santang Town, Hunan Province, China. Ten early season rice cultivars (Zhuliangyou 819, Lingliangyou 268, Lingliangyou 104, Luliangyou 996, Xiangzaoxian… More >

Jin Wang^{1, 2}, Wencheng Chen¹, Lei Wang^{3, *}, R. Simon Sherratt⁴, Osama Alfarraj⁵, Amr Tolba^{5, 6}

CMC-Computers, Materials & Continua, Vol.65, No.3, pp. 2365-2384, 2020, DOI:10.32604/cmc.2020.011567 - 16 September 2020

Abstract As the number of sensor network application scenarios continues to grow, the security problems inherent in this approach have become obstacles that hinder its wide application. However, it has attracted increasing attention from industry and academia. The blockchain is based on a distributed network and has the characteristics of nontampering and traceability of block data. It is thus naturally able to solve the security problems of the sensor networks. Accordingly, this paper first analyzes the security risks associated with data storage in the sensor networks, then proposes using blockchain technology to ensure that data storage… More >

Qigang Sun¹, Jian Wu¹, Dahai Wang^2,*, Yue Xiang², Haitao Liu¹, Xiaobin Sun³

CMES-Computer Modeling in Engineering & Sciences, Vol.124, No.1, pp. 287-302, 2020, DOI:10.32604/cmes.2020.09118 - 19 June 2020

Abstract Downburst event is identified as a major cause to failure of transmission lines in non-coastal regions. In this paper, a novel nonlinear analytical frame for quasi-static buffeting responses of hinged and multi-span insulator-line systems are derived based on the theory of cable structure. The closed-form solutions are presented and applied to predict nonlinear response including displacements and other reactions of the system subjected to a moving downburst wind in a case study. Accuracy and efficiency of the derived analytical frame are validated via comparisons with results from finite element method. More >

Hui Li¹, Cailin Shi^{2, 3}, Xin Liu^{2, 3}, Aziguli Wulamu^{2, 3, *}, Alan Yang⁴

CMC-Computers, Materials & Continua, Vol.64, No.2, pp. 987-1004, 2020, DOI:10.32604/cmc.2020.09812 - 10 June 2020

Abstract The difference in electricity and power usage time leads to an unbalanced current among the three phases in the power grid. The three-phase unbalanced is closely related to power planning and load distribution. When the unbalance occurs, the safe operation of the electrical equipment will be seriously jeopardized. This paper proposes a Hierarchical Temporal Memory (HTM)-based three-phase unbalance prediction model consisted by the encoder for binary coding, the spatial pooler for frequency pattern learning, the temporal pooler for pattern sequence learning, and the sparse distributed representations classifier for unbalance prediction. Following the feasibility of spatialtemporal More >

SAIDA MELIANI¹, SOUMAYA TOUMI¹, HEYTHEM DJAHOUDI², KHALED DEGHDEGH³, KAMEL AMOURA⁴, ABDELGHANI DJAHOUDI^5,*

BIOCELL, Vol.44, No.2, pp. 175-182, 2020, DOI:10.32604/biocell.2020.09097 - 27 May 2020

Abstract Objective: The aim of this study is to detect in vitro the synergetic activity of colistin in combination with imipenem, amikacin or ciprofloxacin, at sub-inhibitory concentrations, against carbapenems-resistant (CR) Acinetobacter baumannii and Pseudomonas aeruginosa strains isolated from various wards in Annaba teaching hospital in eastern Algeria.
Materials and Methods: The minimal inhibitory concentrations (MIC) were determined by broth macrodilution (BMD). Carbapenemase encoding genes were screened using polymerase chain reaction (PCR). The activity of colistin in combination with second antibiotic was evaluated by the Checkerboard Technique.
Results: 39 CR P. aeruginosa and 21 CR A. baumanni strains where collected. The MIC values ranging… More >