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  • Open Access

    ARTICLE

    Excellent Early Outcomes of Combined Chemotherapy With Arsenic Trioxide for Stage 4/M Neuroblastoma in Children: A Multicenter Nonrandomized Controlled Trial

    Chunmou Li*1, Xiaomin Peng*1, Chuchu Feng*1, Xilin Xiong*, Jianxin Li, Ning Liao, Zhen Yang§, Aiguo Liu, Pingping Wu*, Xuehong Liang, Yunyan He, Xin Tian§, Yunbi Lin§, Songmi Wang, Yang Li*

    Oncology Research, Vol.28, No.7-8, pp. 791-800, 2020, DOI:10.3727/096504021X16184815905096

    Abstract This nonrandomized, multicenter cohort, open-label clinical trial evaluated the efficacy and safety of combined chemotherapy with arsenic trioxide (ATO) in children with stage 4/M neuroblastoma (NB). We enrolled patients who were newly diagnosed with NB and assessed as stage 4/M and received either traditional chemotherapy or ATO combined with chemotherapy according to their own wishes. Twenty-two patients were enrolled in the trial group (ATO combined with chemotherapy), and 13 patients were enrolled in the control group (traditional chemotherapy). Objective response rate (ORR) at 4 weeks after completing induction chemotherapy was defined as the main outcome, and adverse events were monitored… More >

  • Open Access

    ARTICLE

    A Stochastic Study of the Fractional Order Model of Waste Plastic in Oceans

    Muneerah Al Nuwairan1,*, Zulqurnain Sabir2, Muhammad Asif Zahoor Raja3, Maryam Alnami1, Hanan Almuslem1

    CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 4441-4454, 2022, DOI:10.32604/cmc.2022.029432

    Abstract In this paper, a fractional order model based on the management of waste plastic in the ocean (FO-MWPO) is numerically investigated. The mathematical form of the FO-MWPO model is categorized into three components, waste plastic, Marine debris, and recycling. The stochastic numerical solvers using the Levenberg-Marquardt backpropagation neural networks (LMQBP-NNs) have been applied to present the numerical solutions of the FO-MWPO system. The competency of the method is tested by taking three variants of the FO-MWPO model based on the fractional order derivatives. The data ratio is provided for training, testing and authorization is 77%, 12%, and 11% respectively. The… More >

  • Open Access

    ARTICLE

    A Novel Stochastic Framework for the MHD Generator in Ocean

    Sakda Noinang1, Zulqurnain Sabir2, Shumaila Javeed3, Muhammad Asif Zahoor Raja4, Dostdar Ali3, Wajaree Weera5,*, Thongchai Botmart5

    CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 3383-3402, 2022, DOI:10.32604/cmc.2022.029166

    Abstract This work aims to study the nonlinear ordinary differential equations (ODEs) system of magnetohydrodynamic (MHD) past over an inclined plate using Levenberg-Marquardt backpropagation neural networks (LMBNNs). The stochastic procedures LMBNNs are provided with three categories of sample statistics, testing, training, and verification. The nonlinear MHD system past over an inclined plate is divided into three profiles, dimensionless momentum, species (salinity), and energy (heat) conservations. The data is applied 15%, 10%, and 75% for validation, testing, and training to solve the nonlinear system of MHD past over an inclined plate. A reference data set is designed to compare the obtained and… More >

  • Open Access

    ARTICLE

    Smart Greenhouse Control via NB-IoT

    Wen-Tsai Sung1, Ching-Hao Weng1, Sung-Jung Hsiao2,*

    Intelligent Automation & Soft Computing, Vol.34, No.3, pp. 1971-1988, 2022, DOI:10.32604/iasc.2022.026927

    Abstract The Internet of Things (IoT) has flourished in recent years, which brings convenience to people’s lives, improves the quality of life, allows more effectively managing and maximizing benefits in industry, and improves weather predictions as the impact of global warming has complicated traditional methods to infer the weather. To this end, agriculture has also given more attention to greenhouse cultivation. In the early days of industrial research, Wi-Fi and ZigBee were used as short-or medium-distance communication technologies for transmissions in the network layer of the IoT architecture. Instead of long-distance communication technologies, such as LoRa and NB-IoT, the features of… More >

  • Open Access

    ARTICLE

    Dynamics of Fractional Differential Model for Schistosomiasis Disease

    Thongchai Botmart1, Wajaree Weera1,*, Muhammad Asif Zahoor Raja2, Zulqurnain Sabir3, Qusain Hiader4, Gilder Cieza Altamirano5, Plinio Junior Muro Solano6, Alfonso Tesen Arroyo6

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 981-999, 2022, DOI:10.32604/cmc.2022.028921

    Abstract In the present study, a design of a fractional order mathematical model is presented based on the schistosomiasis disease. To observe more accurate performances of the results, the use of fractional order derivatives in the mathematical model is introduce based on the schistosomiasis disease is executed. The preliminary design of the fractional order mathematical model focused on schistosomiasis disease is classified as follows: uninfected with schistosomiasis, infected with schistosomiasis, recovered from infection, susceptible snail unafflicted with schistosomiasis disease and susceptible snail afflicted with this disease. The solutions to the proposed system of the fractional order mathematical model will be presented… More >

  • Open Access

    ARTICLE

    Novel Computing for the Delay Differential Two-Prey and One-Predator System

    Prem Junsawang1, Zulqurnain Sabir2, Muhammad Asif Zahoor Raja3, Soheil Salahshour4, Thongchai Botmart5,*, Wajaree Weera3

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 249-263, 2022, DOI:10.32604/cmc.2022.028513

    Abstract The aim of these investigations is to find the numerical performances of the delay differential two-prey and one-predator system. The delay differential models are very significant and always difficult to solve the dynamical kind of ecological nonlinear two-prey and one-predator system. Therefore, a stochastic numerical paradigm based artificial neural network (ANN) along with the Levenberg-Marquardt backpropagation (L-MB) neural networks (NNs), i.e., L-MBNNs is proposed to solve the dynamical two-prey and one-predator model. Three different cases based on the dynamical two-prey and one-predator system have been discussed to check the correctness of the L-MBNNs. The statistic measures of these outcomes of… More >

  • Open Access

    ARTICLE

    Effects of two vectors on the expression of the NbNAC1 transcription factor and preparation of its polyclonal antibody

    FENG ZHU*, QINQIN ZHANG, YANGKAI ZHOU, QIPING ZHANG, MENGYAO CAO, ZHAOLIN JI

    BIOCELL, Vol.46, No.9, pp. 2123-2131, 2022, DOI:10.32604/biocell.2022.020229

    Abstract The NAC (NAM, ATAF, and CUC) superfamily is one of the largest plant-specific families containing transcription factors. An increasing number of studies suggest that NAC1 is involved in plants response to different biotic and abiotic stimulis. Nicotiana benthamiana is a widely used system for evaluating plant-pathogen interactions. In order to study the biochemical function of NbNAC1, NbNAC1 protein and antibody are essential. Therefore, we focused on developing a prokaryotic expression system for producing the Nicotiana benthamiana NbNAC1 protein of in Escherichia coli and the preparation of its polyclonal antibody. Firstly, we constructed two different molecular weight prokaryotic expression vectors: pGE… More >

  • Open Access

    ARTICLE

    UAV-Aided Data Acquisition Using Gaining-Sharing Knowledge Optimization Algorithm

    Rania M Tawfik1, Hazem A. A. Nomer2, M. Saeed Darweesh1,*, Ali Wagdy Mohamed3,4, Hassan Mostafa5,6

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5999-6013, 2022, DOI:10.32604/cmc.2022.028234

    Abstract Unmanned Aerial Vehicles (UAVs) provide a reliable and energy-efficient solution for data collection from the Narrowband Internet of Things (NB-IoT) devices. However, the UAV’s deployment optimization, including locations of the UAV’s stop points, is a necessity to minimize the energy consumption of the UAV and the NB-IoT devices and also to conduct the data collection efficiently. In this regard, this paper proposes Gaining-Sharing Knowledge (GSK) algorithm for optimizing the UAV’s deployment. In GSK, the number of UAV’s stop points in the three-dimensional space is encapsulated into a single individual with a fixed length representing an entire deployment. The superiority of… More >

  • Open Access

    ARTICLE

    Intelligent Networks for Chaotic Fractional-Order Nonlinear Financial Model

    Prem Junswang1, Zulqurnain Sabir2, Muhammad Asif Zahoor Raja3, Waleed Adel4,5, Thongchai Botmart6,*, Wajaree Weera6

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 5015-5030, 2022, DOI:10.32604/cmc.2022.027523

    Abstract The purpose of this paper is to present a numerical approach based on the artificial neural networks (ANNs) for solving a novel fractional chaotic financial model that represents the effect of memory and chaos in the presented system. The method is constructed with the combination of the ANNs along with the Levenberg-Marquardt backpropagation (LMB), named the ANNs-LMB. This technique is tested for solving the novel problem for three cases of the fractional-order values and the obtained results are compared with the reference solution. Fifteen numbers neurons have been used to solve the fractional-order chaotic financial model. The selection of the… More >

  • Open Access

    ARTICLE

    Nonlinear Dynamics of Nervous Stomach Model Using Supervised Neural Networks

    Zulqurnain Sabir1, Manoj Gupta2, Muhammad Asif Zahoor Raja3, N. Seshagiri Rao4, Muhammad Mubashar Hussain5, Faisal Alanazi6, Orawit Thinnukool7, Pattaraporn Khuwuthyakorn7,*

    CMC-Computers, Materials & Continua, Vol.72, No.1, pp. 1627-1644, 2022, DOI:10.32604/cmc.2022.021462

    Abstract The purpose of the current investigations is to solve the nonlinear dynamics based on the nervous stomach model (NSM) using the supervised neural networks (SNNs) along with the novel features of Levenberg-Marquardt backpropagation technique (LMBT), i.e., SNNs-LMBT. The SNNs-LMBT is implemented with three different types of sample data, authentication, testing and training. The ratios for these statistics to solve three different variants of the nonlinear dynamics of the NSM are designated 75% for training, 15% for validation and 10% for testing, respectively. For the numerical measures of the nonlinear dynamics of the NSM, the Runge-Kutta scheme is implemented to form… More >

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