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  • Open Access

    ARTICLE

    Prediction of Proteins Associated with COVID-19 Based Ligand Designing and Molecular Modeling

    Majid Monajjemi1,*, Rahim Esmkhani2, Fatemeh Mollaamin1, Sara Shahriari3

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.3, pp. 907-926, 2020, DOI:10.32604/cmes.2020.012846

    Abstract Current understanding about how the virus that causes COVID-19 spreads is largely based on what is known about similar coronaviruses. Some of the Natural products are suitable drugs against SARS-CoV-2 main protease. For recognizing a strong inhibitor, we have accomplished docking studies on the major virus protease with 4 natural product species as anti COVID-19 (SARS-CoV-2), namely “Vidarabine”, “Cytarabine”, “Gemcitabine” and “Matrine” which have been extracted from Gillan’s leaves plants. These are known as Chuchaq, Trshvash, Cote-Couto and Khlvash in Iran. Among these four studied compounds, Cytarabine appears as a suitable compound with high effectiveness inhibitors to this protease. Finally… More >

  • Open Access

    ARTICLE

    Prediction of Intrinsically Disordered Proteins with a Low Computational Complexity Method

    Jia Yang1, Haiyuan Liu1,*, Hao He2

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.1, pp. 111-123, 2020, DOI:10.32604/cmes.2020.010347

    Abstract The prediction of intrinsically disordered proteins is a hot research area in bio-information. Due to the high cost of experimental methods to evaluate disordered regions of protein sequences, it is becoming increasingly important to predict those regions through computational methods. In this paper, we developed a novel scheme by employing sequence complexity to calculate six features for each residue of a protein sequence, which includes the Shannon entropy, the topological entropy, the sample entropy and three amino acid preferences including Remark 465, Deleage/Roux, and Bfactor(2STD). Particularly, we introduced the sample entropy for calculating time series complexity by mapping the amino… More >

  • Open Access

    REVIEW

    Multifaceted Strategies Used by Root-Knot Nematodes to Parasitize Plants-A Review

    Adnan Shakeel*, Abrar Ahmad Khan, Mohammad Haris

    Phyton-International Journal of Experimental Botany, Vol.89, No.2, pp. 205-215, 2020, DOI:10.32604/phyton.2020.08922

    Abstract Root-knot nematodes being omnipresent in agricultural and horticultural soils are tallied among the most important economic pathogens around the world. For successful parasitism, these nematodes use various strategies to control and manipulate the host plant’s cell machinery. These strategies include the molecular mimicry of some host genes by some nematode secreted effector proteins, secretion of cell wall digesting enzymes and other effector proteins that are responsible for the suppression of defence by the host plant. All these secretions which are released through the stylet, contribute to the formation of specialized feeding sites or giant cells. The effector proteins interfere with… More >

  • Open Access

    ABSTRACT

    Supplement. 6 Workshop: Biology of Ampullariidae Biochemical composition, tissue origin and functional properties of egg perivitellins from Pomacea canaliculata

    MARCOS S. DREON1, HORACIO HERAS1,2, RICARDO J. POLLERO1

    BIOCELL, Vol.30, Suppl.S, pp. 359-365, 2006

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Storage lipids and proteins of Euterpe edulis seeds

    VÍCTOR PANZA1,2, DARIO PIGHIN3, VERÓNICA LÁINEZ2, RICARDO J. POLLERO4, SARA MALDONADO1,2,*

    BIOCELL, Vol.33, No.2, pp. 99-106, 2009, DOI:10.32604/biocell.2009.33.099

    Abstract Comparative studies on fatty acid and protein composition of the endosperm and embryo of palmito (Euterpe edulis Martius) were conducted using gas-liquid chromatography and sodium dodecyl sulfate–polyacrylamide gel electrophoresis. On a dry weight basis, the embryo contained extremely lower amounts of lipids and proteins than did the endosperm, which was associated with the scarce lipid and protein bodies previously reported in axis and cotyledon. The fatty acid composition also exhibited differences between both tissues: (I) the fatty acid diversity was greater in embryo than in endosperm; (II) embryo and endosperm contained predominantly linoleic, palmitic, oleic and stearic acids even though… More >

  • Open Access

    ARTICLE

    Cyclic nucleotide phosphodiesterase inhibition increases tyrosine phosphorylation and hyper motility in normal and pathological human spermatozoa

    ROBERTO YUNES, PEDRO FERNÁNDEZ, GUSTAVO F. DONCEL, ANÍBAL A. ACOSTA

    BIOCELL, Vol.29, No.3, pp. 287-293, 2005, DOI:10.32604/biocell.2005.29.287

    Abstract Our objective was to determine the effect of phosphodiesterase (PDE) inhibition on: 1) tyrosine phosphorylation of human spermatozoa at the tail level; and 2) sperm motion parameters and hyperactivated motility. The study was conducted with normozoospermic and asthenozoospermic samples incubated under in vitro capacitating conditions. The main outcome measures were computer-assisted sperm motion analysis and fluorescent immunodetection of phosphotyrosine-containing proteins. Pentoxifylline (PTX) was used as PDE inhibitor because of its wide use in the clinic. PTX-treatment significantly increased sperm velocity, hyperactivated motility and tyrosine-phosphorylation, both in normo and asthenozoospermic samples. Tyrosine-phosphorylation of tail proteins was highly conspicuous in both types… More >

  • Open Access

    ARTICLE

    Wereke root (Ibervillea sonorae Greene) descriptive characteristics and biochemical generalities of its aqueous extract

    Sinagawa-García SR1, A Gutiérrez-Díez1, A Mora-Olivo2, MC Juárez-Aragón2, JA Torres-Castillo2

    Phyton-International Journal of Experimental Botany, Vol.84, No.2, pp. 358-367, 2015, DOI:10.32604/phyton.2015.84.358

    Abstract A general biochemical description of an aqueous extract obtained from Ibervillea sonorae root was reported; furthermore, a histological description for the root is included. A bromatological analysis was carried out, and it indicated that the study nutritional variables were similar to those reported in other edible tuberous roots including sweet potatoe, mandioca, bean yam and arracacha. For the first time, the presence of an active proteinase at alkaline pH and the inhibitory activity of trypsin were reported for this root. Several medical and bioactive properties have been attributed to the wereke root. Nevertheless, deeper studies are needed to determinate the… More >

  • Open Access

    ARTICLE

    Effect of nitrogen source and concentration to produce proteins in mass cultures of the microalgae Chaetoceros muelleri

    López-Elías JA, R González-Vega, E Márquez-Ríos, W Torres-Arreola

    Phyton-International Journal of Experimental Botany, Vol.84, No.2, pp. 331-337, 2015, DOI:10.32604/phyton.2015.84.331

    Abstract Proteins are one of the major metabolites in biomass from microalgae that constitute the diet of marine organisms grown in aquaculture, and are essential for their growth. The quantity of this component is influenced by nutrients, temperature and light intensity, among others. We examined the growth, biomass production and protein of Chaetoceros muelleri with two sources of nitrogen (nitrate and urea) at three concentrations, using the medium f/2 (0.88 mol/L) (nitrates) as control. The treatments were the medium 2f (3.53 mol/L) and 4f (7.05 mol/L) with NO3-, and the medium f/2 (0.88 mol/L), 2f (3.53mol/L) and 4f (7.05 mol/L) with… More >

  • Open Access

    ARTICLE

    Morphological and immunochemical characterization of the pollen grains of Chenopodium album L. (Chenopodiaceae) in a temperate urban area in Argentina

    Bianchimano AS1, MG Murray2,3, ME Aztiria1, B Montes2,3, ML Calfuán2, MI Prat1

    Phyton-International Journal of Experimental Botany, Vol.83, pp. 9-15, 2014, DOI:10.32604/phyton.2014.83.009

    Abstract Chenopodium album is a very polymorphic, cosmopolitan, annual herb that grows spontaneously in modified soils in wasteland in the outlying urban zones of Bahía Blanca. In this city, the flowering period is mainly during February and March, which coincides with the highest concentrations of this pollen type in the atmosphere of the city. The objective of this study was to characterize the pollen grains of Chenopodium album, both morphologically and immunochemically, that were obtained from three different zones in the urban area of Bahía Blanca. Samples were collected from the three separate zones in the city that were far apart.… More >

  • Open Access

    ARTICLE

    Role of macroalgae in biomonitoring of pollution in «Marchica», the Nador lagoon

    Ben Chekroun K1, A Moumen1, N Rezzoum2, E Sánchez3, M Baghour1

    Phyton-International Journal of Experimental Botany, Vol.82, pp. 31-34, 2013, DOI:10.32604/phyton.2013.82.031

    Abstract The Aquatic system contamination by organic pollutants and heavy metals is one of the most serious problems that might face the environment and organisms as a whole. Interestingly, the accumulation of these pollutants is due to the anthropogenic activity, namely the intensive use of fertilizers to obtain high yields in crop production. In this paper, we compared the levels of chlorophylls, proteins, dry weight and sucrose in some red (Alsidium sp. and Gracilaria sp.) and green algae (Ulva sp.) collected from Mohandis, near Kariat and Bou Areg. Our results indicate that the algae collected nearby Bou Areg, an area well-known… More >

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