V. S. Vaisakhi^1,*, D. Surendran²

Computer Systems Science and Engineering, Vol.46, No.1, pp. 181-193, 2023, DOI:10.32604/csse.2023.032514

Abstract In signal processing and communication systems, digital filters are widely employed. In some circumstances, the reliability of those systems is crucial, necessitating the use of fault tolerant filter implementations. Many strategies have been presented throughout the years to achieve fault tolerance by utilising the structure and properties of the filters. As technology advances, more complicated systems with several filters become possible. Some of the filters in those complicated systems frequently function in parallel, for example, by applying the same filter to various input signals. Recently, a simple strategy for achieving fault tolerance that takes advantage of the availability of parallel… More >

Zhiwei Lin¹, Tianding Chen^1,*, Yingtao Jiang², Hui Wang¹, Shuqin Lin¹, Ming Zhu²

Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 2145-2164, 2023, DOI:10.32604/iasc.2023.035555

Abstract Directly applying the B-spline interpolation function to process plate cams in a computer numerical control (CNC) system may produce verbose tool-path codes and unsmooth trajectories. This paper is devoted to addressing the problem of B-spline fitting for cam pitch curves. Considering that the B-spline curve needs to meet the motion law of the follower to approximate the pitch curve, we use the radial error to quantify the effects of the fitting B-spline curve and the pitch curve. The problem thus boils down to solving a difficult global optimization problem to find the numbers and positions of the control points or… More >

T. Merlin Inbamalar^1,*, Dhandapani Samiappan², R. Ramesh³

Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1899-1913, 2023, DOI:10.32604/iasc.2023.031202

Abstract Conferring to the American Association of Neurological Surgeons (AANS) survey, 85% to 99% of people are affected by spinal cord tumors. The symptoms are varied depending on the tumor’s location and size. Up-to-the-minute, back pain is one of the essential symptoms, but it does not have a specific symptom to recognize at the earlier stage. Numerous significant research studies have been conducted to improve spine tumor recognition accuracy. Nevertheless, the traditional systems are consuming high time to extract the specific region and features. Improper identification of the tumor region affects the predictive tumor rate and causes the maximum error-classification problem.… More >

Akku Madhusudhan^*, Sudhir Kumar Sharma

Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1273-1282, 2023, DOI:10.32604/iasc.2023.030765

Abstract The next step in mobile communication technology, known as 5G, is set to go live in a number of countries in the near future. New wireless applications have high data rates and mobility requirements, which have posed a challenge to mobile communication technology researchers and designers. 5G systems could benefit from the Universal Filtered Multicarrier (UFMC). UFMC is an alternate waveform to orthogonal frequency-division multiplexing (OFDM), in filtering process is performed for a sub-band of subcarriers rather than the entire band of subcarriers Inter Carrier Interference (ICI) between neighbouring users is reduced via the sub-band filtering process, which reduces out-of-band… More >

QIAOJIN JIA^1,2, YUEJUN FU^1,*

BIOCELL, Vol.47, No.3, pp. 627-645, 2023, DOI:10.32604/biocell.2023.026182

Abstract Background: The immune system of insects exerts fundamentally different antiviral mechanisms than mammals. MicroRNAs (miRNAs) play vital roles in developing insect antiviral immunity. MiRNAs expression profiles of insects changed significantly during baculovirus infection. Methods: Differential expression profiles of miRNAs in Spodoptera frugiperda were monitored by next-generation sequencing (NGS) and RT-qPCR during Autographa californica multiple nucleopolyhedrovirus (AcMNPV) infection. The transcription levels of genes were detected by RT-qPCR. The 50% tissue culture infective dose (TCID50) endpoint dilution assay was used to determine the proliferation of progeny virus. Results: NGS revealed that 49 miRNAs were differentially expressed in Sf9 cells, and 10 of… More >

LIJUN DU¹, KAIKAI DOU¹, NIANHAI LIANG^1,2, JIANMIN SUN¹, RU BAI^1,*

BIOCELL, Vol.47, No.3, pp. 547-554, 2023, DOI:10.32604/biocell.2023.025048

Abstract Background: The Warburg effect is considered as a hallmark of various types of cancers, while the regulatory mechanism is poorly understood. Our previous study demonstrated that miR-194-5p directly targets and regulates insulin-like growth factor1 receptor (IGF1R). In this study, we aimed to investigate the role of miR-194-5p in the regulation of the Warburg effect in ovarian cancer cells. Methods: The stable ovarian cell lines with miR-194-5p overexpression or silencing IGF1R expression were established by lentivirus infection. ATP generation, glucose uptake, lactate production and extracellular acidification rate (ECAR) assay were used to analyze the effects of aerobic glycolysis in ovarian cancer… More >

Roberto Altieri^1,2,*, Francesco Certo¹, Marco Garozzo¹, Giacomo Cammarata¹, Massimiliano Maione¹, Giuseppa Fiumanò³, Giuseppe Broggi⁴, Giada Maria Vecchio⁴, Rosario Caltabiano⁴, Gaetano Magro⁴, Giuseppe Barbagallo¹

Oncologie, Vol.24, No.4, pp. 693-706, 2022, DOI:10.32604/oncologie.2022.025393

Abstract Background: Intracranial lymphoma remains a challenging differential diagnosis in daily neurosurgical practice. We analyzed our early experience with a surgical series of frameless neuronavigated biopsies in Primary CNS Lymphomas (PCNSLs), highlighting the importance of using an intraoperative combined imaging protocol (5-ALA fluorescence, i-CT and ¹¹C-MET-PET) to overcome potential targeting errors secondary to tumor volume reduction after corticosteroid therapy. Materials and Methods: All patients treated for PCNLSs at our center in a 24-month period (1/1/2019 to 31/12/2020) were analyzed. Our cohort included 6 patients (4 males), with a median age of 67 years (59–82). A total of 45 samples were evaluated… More >

Mudassir Shams¹, Nasreen Kausar², Ebru Ozbilge^3,*, Alper Bulut³

Computer Systems Science and Engineering, Vol.45, No.3, pp. 2617-2633, 2023, DOI:10.32604/csse.2023.034370

Abstract Engineering and applied mathematics disciplines that involve differential equations in general, and initial value problems in particular, include classical mechanics, thermodynamics, electromagnetism, and the general theory of relativity. A reliable, stable, efficient, and consistent numerical scheme is frequently required for modelling and simulation of a wide range of real-world problems using differential equations. In this study, the tangent slope is assumed to be the contra-harmonic mean, in which the arithmetic mean is used as a correction instead of Euler’s method to improve the efficiency of the improved Euler’s technique for solving ordinary differential equations with initial conditions. The stability, consistency,… More >

Ahmed Zohair Ibrahim^1,*, P. Prakash², V. Sakthivel², P. Prabu³

Computer Systems Science and Engineering, Vol.45, No.3, pp. 2447-2460, 2023, DOI:10.32604/csse.2023.030134

Abstract In order to research brain problems using MRI, PET, and CT neuroimaging, a correct understanding of brainfunction is required. This has been considered in earlier times with the support of traditional algorithms. Deep learning process has also been widely considered in these genomics data processing system. In this research, brain disorder illness incliding Alzheimer’s disease, Schizophrenia and Parkinson’s diseaseis is analyzed owing to misdetection of disorders in neuroimaging data examined by means fo traditional methods. Moeover, deep learning approach is incorporated here for classification purpose of brain disorder with the aid of Deep Belief Networks (DBN). Images are stored in… More >

RUI ZHOU^#, JIANYANG XU^#, LINGWEI WANG^*, JIANXIN LI^*

Oncology Research, Vol.29, No.6, pp. 411-423, 2021, DOI:10.32604/or.2022.026236

Abstract Long noncoding RNAs (lncRNAs) act as key regulators controlling complex cellular behaviors in nonsmall cell lung cancer (NSCLC). We investigated the expression of lncRNA PRRT3 antisense RNA 1 (PRRT3-AS1) in paired samples of NSCLC and adjacent normal tissues from a patient cohort in our hospital using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) and found that it was significantly higher in NSCLC tissue than in normal tissue, consistent with The Cancer Genome Atlas database. Furthermore, functional investigation revealed that lncRNA PRRT3-AS1 depletion inhibited NSCLC-cell proliferation, colony formation, invasion, and migration, whereas its overexpression exerted the opposite effects. Moreover, PRRT3-AS1… More >