Asere Gbenga Femi^1,*, Monday Osagie Adenomon¹, Gilbert Imuetinyan Osaze Aimufua¹, Umar Ibrahim²

Journal of Cyber Security, Vol.7, pp. 377-394, 2025, DOI:10.32604/jcs.2025.069185 - 30 September 2025

Abstract Effective data protection frameworks are vital for safeguarding personal information, fostering digital trust, and ensuring alignment with global standards. In Nigeria, the Nigeria Data Protection Regulation (NDPR), administered by the National Information Technology Development Agency (NITDA), constitutes the nation’s primary privacy framework, harmonized with principles of the European Union’s GDPR. This study evaluates NDPR compliance across six strategic sectors; finance, telecommunications, education, health, Small and Medium-sized Enterprises (SMEs), and the public sector using a mixed-methods design. Data from 615 respondents in 30 organizations were collected through surveys, interviews, and document analysis. Findings reveal notable sectoral… More >

Fan Chen^*, Tianhui Zhang, Man Wang, Zhiheng Zhuang, Qiang Zhang, Zihan Ma

Energy Engineering, Vol.122, No.10, pp. 4099-4120, 2025, DOI:10.32604/ee.2025.069346 - 30 September 2025

Abstract The configuration of a hybrid energy storage system (HESS) plays a pivotal role in mitigating wind power fluctuations and enabling primary frequency regulation, thereby enhancing the active power support capability of wind power integration systems. However, most existing studies on HESS capacity configuration overlook the self-recovery control of the state of charge (SOC), creating challenges in sustaining capacity during long-term operation. This omission can impair frequency regulation performance, increase capacity requirements, and shorten battery lifespan. To address these challenges, this study proposes a bi-level planning–operation capacity configuration model that explicitly incorporates SOC self-recovery control. In… More >

Jinyu Guo^*, Xingxu Zhu, Zezhong Liu, Cuiping Li

Energy Engineering, Vol.122, No.10, pp. 3961-3983, 2025, DOI:10.32604/ee.2025.067811 - 30 September 2025

Abstract In high-renewable-energy power systems, the demand for fast-responding capabilities is growing. To address the limitations of conventional closed-loop frequency control, where the integral coefficient cannot dynamically adjust the frequency regulation command based on the state of charge (SoC) of energy storage units, this paper proposes a secondary frequency regulation control strategy based on variable integral coefficients for multiple energy storage units. First, a power-uniform controller is designed to ensure that thermal power units gradually take on more regulation power during the frequency regulation process. Next, a control framework based on variable integral coefficients is proposed… More >

Ana M. Vela-AlcáNtara¹, Diego J. HernáNdez-SáNchez^1,2, Elisa Tamariz^1,*

BIOCELL, Vol.49, No.9, pp. 1663-1695, 2025, DOI:10.32604/biocell.2025.066201 - 25 September 2025

Abstract Cells are exposed to various mechanical forces, including extracellular and intracellular forces such as stiffness, tension, compression, viscosity, and shear stress, which regulate cell biology. The process of transducing mechanical stimuli into biochemical signals is termed mechanotransduction. These mechanical forces can regulate protein and gene expression, thereby impacting cell morphology, adhesion, proliferation, apoptosis, and migration. During cancer development, significant changes in extracellular and intracellular mechanical properties occur, resulting in altered mechanical inputs to which cells are exposed. MicroRNAs (miRNAs), key post-transcriptional regulators of gene and protein expression, are increasingly recognized as mechanosensitive molecules involved in More >

Imene Tatar Caliskan^1,2, George Dzorgbenya Ametefe³, Aziz Caliskan⁴, Su-Ee Lau^1,5, Yvonne Jing Mei Liew⁶, Nur Kusaira Khairul Ikram⁵, Boon Chin Tan^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.8, pp. 2229-2254, 2025, DOI:10.32604/phyton.2025.067225 - 29 August 2025

Abstract Myeloblastosis (MYB) transcription factors (TFs) are evolutionarily conserved regulatory proteins that are crucial for plant growth, development, secondary metabolism, and stress adaptation. Recent studies have highlighted their crucial role in coordinating growth–defense trade-offs through transcriptional regulation of key biosynthetic and stress-response genes. Despite extensive functional characterization in model plants such as Arabidopsis thaliana, systematically evaluating the broader functional landscape of MYB TFs across diverse species and contexts remains necessary. This systematic review integrates results from 24 peer-reviewed studies sourced from Scopus and Web of Science, focusing on the functional diversity of MYB TFs, particularly in relation… More >

Xiaobing Zhou^1,#, Ying Li^2,#, Zizi Jing¹, Wei Yu¹, Jianbin Chen^1,*

Oncology Research, Vol.33, No.9, pp. 2399-2420, 2025, DOI:10.32604/or.2025.063700 - 28 August 2025

Abstract Background: Multiple myeloma (MM) remains a formidable clinical challenge due to its high relapse rate and resistance to existing therapies. Estrogen-related receptor gamma (ERRγ), a nuclear receptor critical for cellular energy metabolism, has been implicated in various cancers. but its role in MM remains unclear. Methods: ERRγ expression was assessed using bioinformatics and RT-qPCR. Functional studies were conducted through siRNA-mediated ERRγ knockdown and treatment with the inverse agonist GSK5182 to examine their effects on MM cell proliferation and apoptosis. Results: ERRγ was significantly upregulated in the bone marrow of MM patients, correlating with advanced clinical stages… More > Graphic Abstract

Yuhang Jiang^#, Yijun Xu^#, Qi Zhu, Yingxia Wu, Zhe Wang, Shuang He, Shiyong Yu^*, Honggang Xiang^*

Oncology Research, Vol.33, No.9, pp. 2379-2398, 2025, DOI:10.32604/or.2025.063501 - 28 August 2025

Abstract Background: Colorectal cancer (CRC) is common and deadly, often leading to metastasis, challenging treatment, and poor outcomes. Understanding its molecular basis is crucial for developing effective therapies. Aims: This study aimed to investigate the role of Myosin Heavy Chain 11 (MYH11) in CRC progression, especially its effects on epithelial-mesenchymal transition (EMT) and cell behavior, and to explore its potential regulation by the EMT transcription factor zinc finger E-box binding homeobox 1 (ZEB1). Methods: Differential expression analysis was performed in the GSE123390 and TCGA-READ datasets, and 317 intersection genes were identified. The hub gene MYH11 was identified… More >

Yi Zhang¹, Hua Jin^2,*

BIOCELL, Vol.49, No.8, pp. 1529-1543, 2025, DOI:10.32604/biocell.2025.066479 - 29 August 2025

Abstract Objectives: The present study investigated whether Tripartite Motif-Containing Protein 32 (TRIM32) contributes to the aberrant activation of keloid fibroblasts (KFs) via glycolysis. Methods: The expression levels of TRIM32, pyruvate dehydrogenase kinase 1 (PDK1), hexokinase 2 (HK2), and glucose transporter 1 (GLUT1) in normal human skin fibroblasts (NFs) and KFs were analyzed using RT-qPCR analyses and western blotting. Cellular proliferation, invasion, and migration were evaluated using Transwell, wound healing, 5-ethynyl-2^′-deoxyuridine (EdU), and cell counting kit-8 (CCK-8) assays. The extracellular acidification rate (ECAR) was measured using the XF96 Extracellular Flux Analyzer. Glucose uptake and ATP production were measured using… More >

Xiaoliang Zhu, Hao Chen, Xin Yang, Zhicheng Dai, Liang Zhao^*

CMC-Computers, Materials & Continua, Vol.85, No.1, pp. 1585-1602, 2025, DOI:10.32604/cmc.2025.066147 - 29 August 2025

Abstract Facial expression datasets commonly exhibit imbalances between various categories or between difficult and simple samples. This imbalance introduces bias into feature extraction within facial expression recognition (FER) models, which hinders the algorithm’s comprehension of emotional states and reduces the overall recognition accuracy. A novel FER model is introduced to address these issues. It integrates rebalancing mechanisms to regulate attention consistency and focus, offering enhanced efficacy. Our approach proposes the following improvements: (i) rebalancing weights are used to enhance the consistency between the heatmaps of an original face sample and its horizontally flipped counterpart; (ii) coefficient More >

Cuiping Li¹, Ziyun Zong¹, Xingxu Zhu¹, Zheng Fang², Caiqi Jia³, Wenbo Si⁴, Gangui Yan¹, Junhui Li^1,*

Energy Engineering, Vol.122, No.9, pp. 3459-3485, 2025, DOI:10.32604/ee.2025.066629 - 26 August 2025

Abstract In response to the issue of determining the appropriate capacity when hybrid energy storage systems (HESS) collaborate with thermal power units (TPU) in the system’s secondary frequency regulation, a configuration method for HESS based on the analysis of frequency regulation demand analysis is proposed. And a corresponding simulation platform is developed. Firstly, a frequency modulation demand method for reducing the frequency modulation losses of TPU is proposed. Secondly, taking into comprehensive consideration that flywheel energy storage features rapid power response and battery energy storage has the characteristic of high energy density, a coordinated control strategy… More > Graphic Abstract