Ashaduzzaman Sagar¹ , Md. Sabibul Haque¹, Md. Alamgir Hossain¹, Md. Nesar Uddin¹, Jannat E. Tajkia¹, Md. Ashik Mia¹, Toufika Hossain Shabi², Md. Solaiman Ali Fakir¹, Md. Abdul Kader^3,4,5, Walid Soufan⁶, Md. Atikur Rahman⁷, Muhammad Aamir Iqbal⁸, Mohammad Sohidul Islam⁹, Ayman El Sabagh^10,*, A. K. M. Zakir Hossain^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.8, pp. 2349-2368, 2023, DOI:10.32604/phyton.2023.028974

Abstract Salt stress is one of the major limitations to modern agriculture that negatively influences plant growth and productivity. Salt tolerant cultivar can provide excellent solution to enhance stress tolerance with plant fitness to unfavorable environments. Therefore, this study was aimed to screen salt tolerant sorghum genotypes through evaluating of different morphological, biochemical, and physiological attributes in response to salinity stress. In this study, we have been evaluated total six sorghum genotypes including Hybrid sorgo, Debgiri, BD-703, BD-706, BD-707, and BD-725 under salt stress (12 dS m⁻¹ NaCl). The response variables included length and weight of root and shoot, root: shoot… More >

BINWU BAO, JINPENG WANG, YANXIA LI, FEN FENG, ZHONGXIANG JI, ZHUOMA LUORENG^*, XINGPING WANG^*

BIOCELL, Vol.47, No.7, pp. 1509-1518, 2023, DOI:10.32604/biocell.2023.028646

Abstract Bovine oocytes are one of the indispensable cells in cattle reproduction and have become a research hot spot in cattle reproduction in recent years. The maturation process of oocytes is mainly regulated by enzymes, hormones, cytokines, and other molecules. The factors affecting cattle oocyte maturation have been previously studied to clarify the molecular mechanisms of cattle oocyte maturation. In this review article, phospholipid protein-3-kinase/protein kinase B, mitogen-activated protein kinase/extracellular signal-regulated kinase, Janus kinase/signal transducer and activator of transcription, epidermal growth factor receptor/extracellular signal-regulated kinase, and other signaling pathways related to oocyte maturation are discussed. In addition, the molecular mechanisms of… More >

YUE CAO, LIN HU, YISHU TANG^*

BIOCELL, Vol.47, No.7, pp. 1537-1548, 2023, DOI:10.32604/biocell.2023.027205

Abstract Backgrounds: Both hepatitis B virus X protein (HBx) and microRNA-221 (miR-221) have been implicated in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The present study demonstrates that HBx promotes HCC cell proliferation via the C-X-C motif chemokine ligand 12-C-X-C chemokine receptor type 4 (CXCL12-CXCR4) axis. We predict that HBx/miR-221-mediated CXCL12/CXCR4 signaling induces NKT cells to promote HBV-related HCC. Methods: After miR-221 mimic, miR-221 mimic negative control, miR-221 inhibitor, miR-221 inhibitor negative control were transfected into cells, the expression of CXCL12 and miR-221 was detected by qPCR and western blot. Then we constructed a stable HBV-HCC cell line.… More >

Xiaoming Fei^*

Intelligent Automation & Soft Computing, Vol.37, No.2, pp. 1293-1309, 2023, DOI:10.32604/iasc.2023.038607

Abstract With the acceleration of urbanization in China, the discharge of domestic sewage and industrial wastewater is increasing, and accidents of sewage spilling out and polluting the environment occur from time to time. Problems such as imperfect facilities and backward control methods are common in the urban drainage network systems in China. Efficient drainage not only strengthens infrastructure such as rain and sewage diversion, pollution source monitoring, transportation, drainage and storage but also urgently needs technical means to monitor and optimize production and operation. Aiming at the optimal control of single-stage pumping stations and the coordinated control between two-stage pumping stations,… More >

RYAN STARK^*

BIOCELL, Vol.47, No.6, pp. 1191-1198, 2023, DOI:10.32604/biocell.2023.027838

Abstract Protein-mediated interactions are the fundamental mechanism through which cells regulate health and disease. These interactions require physical contact between proteins and their respective targets of interest. These targets include not only other proteins but also nucleic acids and other important molecules as well. These proteins are often involved in multibody complexes that work dynamically to regulate cellular health and function. Various techniques have been adapted to study these important interactions, such as affinity-based assays, mass spectrometry, and fluorescent detection. The application of these techniques has led to a greater understanding of how protein interactions are responsible for both the instigation… More >

Shunde Su^1,2,#, Huan Chang^3,#, Xiangyang Kang^1,*, Renhua Zheng^2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.6, pp. 1713-1723, 2023, DOI:10.32604/phyton.2023.027586

Abstract As the reproductive organ of the endangered species Fokienia hodginsii, the size of the cones is a constraint on the reproductive renewal of the population. In this study, the molecular basis of the influence of cone size on F. hodginsii was elucidated by comparing the phenotype, biochemistry, and transcriptome of two cultivars of F. hodginsii (‘FJ431’ and ‘FJ415’). The two cultivars differed significantly in cone size, with FJ431 having a significantly larger cone size and weight than FJ415, 1.32 and 1.90 times that of FJ415, respectively. RNA-Seq analysis of both cultivars retrieved 75,940 genes whose approximate functions were classified as… More >

HAN WANG^1,2,#, YANG SUN^1,2,#, XIAOXU ZHANG^2,3, XIAOYING WANG⁴, YUJUN XIA^1,*, LISHENG WANG^1,2,*

BIOCELL, Vol.47, No.5, pp. 1107-1115, 2023, DOI:10.32604/biocell.2023.027131

Abstract Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract. The destruction of the intestinal epithelial barrier is one of the major pathological processes in IBD pathology. Growing evidence indicated that epithelial cell ferroptosis is linked to IBD and is considered a target process. Methods: RAS-selective lethal 3 (RSL3) was used to induce ferroptosis in intestinal epithelial cell line No. 6 (IEC-6) cells, and cell ferroptosis and the effects of tanshinone IIA (Tan IIA) were determined by cell counting kit-8 (CCK-8), reactive oxygen species (ROS) staining, Giemsa staining and transmission electron microscope (TEM). The cell viability… More >

XIANGCHAO DING^1,#, YANG ZHAO^2,#, XINGHUA ZHANG¹, HUIQING LIN^1,*

BIOCELL, Vol.47, No.5, pp. 1117-1126, 2023, DOI:10.32604/biocell.2023.026715

Abstract Background: Long-chain non-coding RNA (lncRNA) LINC00609 is a potential tumor suppressor, but the mechanism of action in non-small cell lung cancer (NSCLC) is yet to be understood.Objectives: The effects of LINC00609 on A549 cell proliferation, apoptosis, and cell cycle arrest were investigated. Methods: The LINC00609 levels in NSCLC and normal tissues were analyzed by bioinformatics. Expressions of LINC00609, miR-128-3p, and Rho family GTPase 3 (RND3) in NSCLC cells (A549) were determined by qRT-PCR. Bioinformatics analysis predicted target genes and dual-luciferase reporter assays to ensure that LINC00609 targeted miR-128-3p and miR-128-3p targeted RND3. The proliferation of cells was determined using EDU… More >

Wei Chen¹, Na Sun¹, Zhicheng Ma², Wenfei Liu², Haiying Dong^1,*

Energy Engineering, Vol.120, No.6, pp. 1445-1464, 2023, DOI:10.32604/ee.2023.027158

Abstract To address the frequency fluctuation problem caused by the power dynamic imbalance between the power system and the load when a large number of new energy sources are connected to the grid, a two-layer fuzzy control strategy is proposed for the participation of the energy storage battery system in FM. Firstly, considering the coordination of FM units responding to automatic power generation control commands, a comprehensive allocation strategy of two signals under automatic power generation control commands is proposed to give full play to the advantages of two FM signals while enabling better coordination of two FM units responding to… More > Graphic Abstract

QIAO ZHOU^1,2,3, JIAN LIU^2,4, LING XIN⁴, YANYAN FANG^2,4, LEI WAN^2,4, DAN HUANG^2,4, JINCHEN GUO¹, JIANTING WEN^2,4

BIOCELL, Vol.47, No.4, pp. 761-772, 2023, DOI:10.32604/biocell.2023.026698

Abstract The pathophysiology of osteoarthritis (OA) is multifactorial, with the primary risk factors being obesity, age, environmental variables, and genetic predisposition. The available evidence suggests that genetic diversity does not adequately account for all clinical characteristics and heterogeneity of OA. Genetics has emerged as a nascent and crucial area of research in OA. The epigenetic module presents a potential link between genetic and environmental risk factors and the susceptibility and pathogenesis of OA. As a critical epigenetic alteration, DNA methylation has been shown to have an important role in the etiology of OA and is a viable biomarker for predicting disease… More >