Yuejiao Wang, Zhong Ma^*, Chaojie Yang, Yu Yang, Lu Wei

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 819-836, 2024, DOI:10.32604/cmc.2024.047108

Abstract The quantization algorithm compresses the original network by reducing the numerical bit width of the model, which improves the computation speed. Because different layers have different redundancy and sensitivity to data bit width. Reducing the data bit width will result in a loss of accuracy. Therefore, it is difficult to determine the optimal bit width for different parts of the network with guaranteed accuracy. Mixed precision quantization can effectively reduce the amount of computation while keeping the model accuracy basically unchanged. In this paper, a hardware-aware mixed precision quantization strategy optimal assignment algorithm adapted to low bit width is proposed,… More >

Parth Khandelwal¹, Harshit², Indranil Manna^1,3,*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1727-1755, 2024, DOI:10.32604/cmc.2024.042752

Abstract Metallic alloys for a given application are usually designed to achieve the desired properties by devising experiments based on experience, thermodynamic and kinetic principles, and various modeling and simulation exercises. However, the influence of process parameters and material properties is often non-linear and non-colligative. In recent years, machine learning (ML) has emerged as a promising tool to deal with the complex interrelation between composition, properties, and process parameters to facilitate accelerated discovery and development of new alloys and functionalities. In this study, we adopt an ML-based approach, coupled with genetic algorithm (GA) principles, to design novel copper alloys for achieving… More > Graphic Abstract

ANDI ZHAO^1,2,#, YUE WANG^3,#, ZIJIN WANG^1,2, QING SHAO^1,2, QI GONG^1,2, HUI ZHU^1,2, SHIYA SHEN^1,2, HU LIU^1,2,*, XUEJUAN CHEN^1,2,*

Oncology Research, Vol.32, No.5, pp. 983-998, 2024, DOI:10.32604/or.2024.045972

Abstract Numerous studies have characterized the critical role of circular RNAs (circRNAs) as regulatory factors in the progression of multiple cancers. However, the biological functions of circRNAs and their underlying molecular mechanisms in the progression of uveal melanoma (UM) remain enigmatic. In this study, we identified a novel circRNA, circ_0053943, through re-analysis of UM microarray data and quantitative RT-PCR. Circ_0053943 was found to be upregulated in UM and to promote the proliferation and metastatic ability of UM cells in both in vitro and in vivo settings. Mechanistically, circ_0053943 was observed to bind to the KH1 and KH2 domains of insulin-like growth… More > Graphic Abstract

Xukai Ren^1,2,*, Huanwei Yu², Xianfeng Chen², Yantong Tang², Guobiao Wang^1,*, Xiyong Du²

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 647-663, 2024, DOI:10.32604/cmes.2024.048782

Abstract Stirred reactors are key equipment in production, and unpredictable failures will result in significant economic losses and safety issues. Therefore, it is necessary to monitor its health state. To achieve this goal, in this study, five states of the stirred reactor were firstly preset: normal, shaft bending, blade eccentricity, bearing wear, and bolt looseness. Vibration signals along x, y and z axes were collected and analyzed in both the time domain and frequency domain. Secondly, 93 statistical features were extracted and evaluated by ReliefF, Maximal Information Coefficient (MIC) and XGBoost. The above evaluation results were then fused by D-S evidence… More >

Xue-Qin Li¹, Lu-Kai Song^2,3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 665-684, 2024, DOI:10.32604/cmes.2024.048445

Abstract Fatigue reliability-based design optimization of aeroengine structures involves multiple repeated calculations of reliability degree and large-scale calls of implicit high-nonlinearity limit state function, leading to the traditional direct Monte Claro and surrogate methods prone to unacceptable computing efficiency and accuracy. In this case, by fusing the random subspace strategy and weight allocation technology into bagging ensemble theory, a random forest (RF) model is presented to enhance the computing efficiency of reliability degree; moreover, by embedding the RF model into multilevel optimization model, an efficient RF-assisted fatigue reliability-based design optimization framework is developed. Regarding the low-cycle fatigue reliability-based design optimization of… More >

Dawei Ruan¹, Mingwei Hu^1,2,3,4,5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 821-844, 2024, DOI:10.32604/cmes.2024.048392

Abstract The specialized equipment utilized in long-line tunnel engineering is evolving towards large-scale, multifunctional, and complex orientations. The vibration caused by the high-frequency units during regular operation is supported by the foundation of the units, and the magnitude of vibration and the operating frequency fluctuate in different engineering contexts, leading to variations in the dynamic response of the foundation. The high-frequency units yield significantly diverse outcomes under different startup conditions and times, resulting in failure to meet operational requirements, influencing the normal function of the tunnel, and causing harm to the foundation structure, personnel, and property in severe cases. This article… More >

Jipeng Xie^1,2, Guolai Yang^1,*, Liqun Wang¹, Lei Li¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 793-819, 2024, DOI:10.32604/cmes.2024.048174

Abstract To enhance the comprehensive performance of artillery internal ballistics—encompassing power, accuracy, and service life—this study proposed a multi-stage multidisciplinary design optimization (MS-MDO) method. First, the comprehensive artillery internal ballistic dynamics (AIBD) model, based on propellant combustion, rotation band engraving, projectile axial motion, and rifling wear models, was established and validated. This model was systematically decomposed into subsystems from a system engineering perspective. The study then detailed the MS-MDO methodology, which included Stage I (MDO stage) employing an improved collaborative optimization method for consistent design variables, and Stage II (Performance Optimization) focusing on the independent optimization of local design variables and… More >

Zibin Mao¹, Qinghai Zhao^1,2,*, Liang Zhang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 757-792, 2024, DOI:10.32604/cmes.2024.048016

Abstract This paper proposes a multi-material topology optimization method based on the hybrid reliability of the probability-ellipsoid model with stress constraint for the stochastic uncertainty and epistemic uncertainty of mechanical loads in optimization design. The probabilistic model is combined with the ellipsoidal model to describe the uncertainty of mechanical loads. The topology optimization formula is combined with the ordered solid isotropic material with penalization (ordered-SIMP) multi-material interpolation model. The stresses of all elements are integrated into a global stress measurement that approximates the maximum stress using the normalized p-norm function. Furthermore, the sequential optimization and reliability assessment (SORA) is applied to… More >

Guogang Gao¹, Lei Xu¹, Tianpeng Huang^2,*, Xuliang Zhao¹, Lihua Huang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 305-323, 2024, DOI:10.32604/cmes.2024.047899

Abstract The Rotary Inverted Pendulum (RIP) is a widely used underactuated mechanical system in various applications such as bipedal robots and skyscraper stabilization where attitude control presents a significant challenge. Despite the implementation of various control strategies to maintain equilibrium, optimally tuning control gains to effectively mitigate uncertain nonlinearities in system dynamics remains elusive. Existing methods frequently rely on extensive experimental data or the designer’s expertise, presenting a notable drawback. This paper proposes a novel tracking control approach for RIP, utilizing a Linear Quadratic Regulator (LQR) in combination with a reduced-order observer. Initially, the RIP system is mathematically modeled using the… More >

Xianwei Jiang¹, Yanqiong Zhang^1,*, Juan Lei¹, Yudong Zhang^2,3,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1-40, 2024, DOI:10.32604/cmes.2024.047649

Abstract Research on Chinese Sign Language (CSL) provides convenience and support for individuals with hearing impairments to communicate and integrate into society. This article reviews the relevant literature on Chinese Sign Language Recognition (CSLR) in the past 20 years. Hidden Markov Models (HMM), Support Vector Machines (SVM), and Dynamic Time Warping (DTW) were found to be the most commonly employed technologies among traditional identification methods. Benefiting from the rapid development of computer vision and artificial intelligence technology, Convolutional Neural Networks (CNN), 3D-CNN, YOLO, Capsule Network (CapsNet) and various deep neural networks have sprung up. Deep Neural Networks (DNNs) and their derived… More >