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  • Open Access

    ARTICLE

    Proposer un accompagnement au sevrage tabagique aux patients atteints de cancer : le rôle des associations proposant des soins de support. Exemple de la Ligue Contre le Cancer Gironde

    Océane Phanatzis1,2,*, Rébecca Ratel1,2, Isabelle Barcos1,2, Marie Daspas3, Emmanuelle Clairembault3, François Alla1,2

    Psycho-Oncologie, Vol.17, No.3, pp. 133-145, 2023, DOI:10.32604/po.2023.044916

    Abstract Objectif : L’objectif de cet article est d’exposer les composantes interventionnelles et contextuelles d’un accompagnement au sevrage tabagique dans le cadre des soins oncologiques de support (SOS) délivrés par une association, qui soit viable en contexte français et efficace, et de décrire le processus de recherche partenariale dans lequel elles ont été élaborées. Méthodes : L’intervention a été développée à partir d’un ensemble de données recueillies lors d’une étude de viabilité à la mise en place d’une offre de sevrage tabagique au sein de la Ligue Contre le Cancer Gironde, une revue de la portée sur les interventions probantes et… More >

  • Open Access

    ARTICLE

    Implémentation d’une intervention psychosociale StomieCare auprès de patients opérés d’un cancer du rectum avec stomie temporaire : une étude pilote de faisabilité, d’acceptabilité et d’efficacité

    Stéphane Faury1,*, Katia M’Bailara1,2, Eric Rullier3, Quentin Denost4, Bruno Quintard1

    Psycho-Oncologie, Vol.17, No.3, pp. 147-157, 2023, DOI:10.32604/po.2023.044901

    Abstract L’objectif de cette étude est d’évaluer la faisabilité, l’acceptabilité et l’efficacité d’une intervention psychosociale en individuel (appelée StomieCare) auprès de patients atteints d’un cancer du rectum et traités par chirurgie avec stomie temporaire. Cette intervention, en trois séances individuelles, comprend des discussions thématiques autour de problèmes communs relatifs à la maladie et/ou la stomie comme l’impact du cancer et de ces traitements sur la qualité de vie, l’estime de soi, d’apport d’informations et d’apprentissage de techniques (résolution de problème et restructuration cognitive). Trente-sept patients atteints d’un cancer du rectum et traités par chirurgie avec stomie temporaire ont été recrutés et… More >

  • Open Access

    ARTICLE

    A Large-Scale Group Decision Making Model Based on Trust Relationship and Social Network Updating

    Rongrong Ren1,2, Luyang Su1,2, Xinyu Meng1,2, Jianfang Wang3, Meng Zhao1,2,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 429-458, 2024, DOI:10.32604/cmes.2023.027310

    Abstract With the development of big data and social computing, large-scale group decision making (LGDM) is now merging with social networks. Using social network analysis (SNA), this study proposes an LGDM consensus model that considers the trust relationship among decision makers (DMs). In the process of consensus measurement: the social network is constructed according to the social relationship among DMs, and the Louvain method is introduced to classify social networks to form subgroups. In this study, the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights. In the process of consensus improvement: A… More >

  • Open Access

    ARTICLE

    Identification of lncRNAs associated with T cells as potential biomarkers and therapeutic targets in lung adenocarcinoma

    LU SUN1,2, HUAICHENG TAN1, TING YU3, RUICHAO LIANG4,*

    Oncology Research, Vol.31, No.6, pp. 967-988, 2023, DOI:10.32604/or.2023.042309

    Abstract Lung adenocarcinoma (LUAD) is the most common and deadliest subtype of lung cancer. To select more targeted and effective treatments for individuals, further advances in classifying LUAD are urgently needed. The number, type, and function of T cells in the tumor microenvironment (TME) determine the progression and treatment response of LUAD. Long noncoding RNAs (lncRNAs), may regulate T cell differentiation, development, and activation. Thus, our aim was to identify T cell-related lncRNAs (T cell-Lncs) in LUAD and to investigate whether T cell-Lncs could serve as potential stratifiers and therapeutic targets. Seven T cell-Lncs were identified to further establish the T… More >

  • Open Access

    ARTICLE

    ScRNA-seq reveals the correlation between M2 phenotype of tumor-associated macrophages and lymph node metastasis of breast cancer

    JUN SHEN1,#, HONGFANG MA2,#, YONGXIA CHEN3, JIANGUO SHEN1,*

    Oncology Research, Vol.31, No.6, pp. 955-966, 2023, DOI:10.32604/or.2023.029638

    Abstract The process of lymphatic metastasis was proved to be associated with podoplanin-expressing macrophages in breast cancer (BC). This study aimed to investigate the role of the M2 phenotype of tumor-associated macrophages and mine the key M2 macrophages-related genes for lymph node metastasis in BC. We downloaded the GSE158399 dataset from the Gene Expression Omnibus (GEO) database, which includes transcriptomic profiles of individual cells from primary tumors, negative lymph nodes (NLNs), and positive lymph nodes (PLNs) of breast cancer patients. The cell subsets were identified by clustering analysis after quality control of the scRNA-seq using Seurat. The activation and migration capability… More >

  • Open Access

    ARTICLE

    A Positive Influence Maximization Algorithm in Signed Social Networks

    Wenlong Zhu1,2,*, Yang Huang1, Shuangshuang Yang3, Yu Miao1, Chongyuan Peng1

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1977-1994, 2023, DOI:10.32604/cmc.2023.040998

    Abstract The influence maximization (IM) problem aims to find a set of seed nodes that maximizes the spread of their influence in a social network. The positive influence maximization (PIM) problem is an extension of the IM problem, which consider the polar relation of nodes in signed social networks so that the positive influence of seeds can be the most widely spread. To solve the PIM problem, this paper proposes the polar and decay related independent cascade (IC-PD) model to simulate the influence propagation of nodes and the decay of information during the influence propagation in signed social networks. To overcome… More >

  • Open Access

    ARTICLE

    Deep Learning Based Cyber Event Detection from Open-Source Re-Emerging Social Data

    Farah Mohammad1,*, Saad Al-Ahmadi2, Jalal Al-Muhtadi1,2

    CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1423-1438, 2023, DOI:10.32604/cmc.2023.035741

    Abstract Social media forums have emerged as the most popular form of communication in the modern technology era, allowing people to discuss and express their opinions. This increases the amount of material being shared on social media sites. There is a wealth of information about the threat that may be found in such open data sources. The security of already-deployed software and systems relies heavily on the timely detection of newly-emerging threats to their safety that can be gleaned from such information. Despite the fact that several models for detecting cybersecurity events have been presented, it remains challenging to extract security… More >

  • Open Access

    PROCEEDINGS

    Peridynamic Analysis on Thermal-Elastic Deformation of Isotropic Plate with Traction Boundary Condition

    Ming Yu1, Zeyuan Zhou1, Zaixing Huang1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09264

    Abstract How to well characterize traction boundary condition is always a difficult problem in peridynamics. In order to solve this problem, an integral term of boundary traction weighted by a tensor-typical transfer function is added to the original peridynamic motion equation, to form the so-called the traction-associated peridynamic motion equation. The traction-associated peridynamic motion equation is proved to be compatible with the conservation laws of linear and angular momentum. The conservation law of energy is also verified to have the same form as the original peridynamics advanced by Silling. Therefore, the constitutive models in the original peridynamics can be directly applied… More >

  • Open Access

    ARTICLE

    The potency of N, N'-diphenyl-1,4-phenylenediamine and adipose-derived stem cell co-administration in alleviating hepatorenal dysfunction complications associated with type 1 diabetes mellitus in rats

    HANY M. ABD EL-LATEEF1,2,*, SAFA H. QAHL3, EMAN FAYAD4, SARAH A. ALTALHI4, IBRAHIM JAFRI4, EL SHAIMAA SHABANA5, MARWA K. DARWISH6,7, REHAB MAHER8, SAAD SHAABAN1,9, SHADY G. EL-SAWAH10,*

    BIOCELL, Vol.47, No.8, pp. 1885-1895, 2023, DOI:10.32604/biocell.2023.030680

    Abstract Background: The increasing occurrence of diabetes mellitus (DM) noted worldwide has considerably elicited concern in the recent past. DM is associated with elevated vascular complications, morbidity, mortality, and poor quality of life. In this context, mesenchymal stem cells (MSCs) have shown significant therapeutic potentialities in managing and curing type 1 DM owing to their self-renewable, immunosuppressive, and differentiation capacities. We investigated the potential action of N, N′-diphenyl-1,4-phenylenediamine (DPPD), a well-known synthetic antioxidant to enhance the therapeutic ability of the adipose-derived stem cells (AD-MSCs) in alleviating kidney and liver complications in diabetic rats. Methods: Over the four weeks of experiments, albino… More > Graphic Abstract

    The potency of <i>N</i>, <i>N'</i>-diphenyl-1,4-phenylenediamine and adipose-derived stem cell co-administration in alleviating hepatorenal dysfunction complications associated with type 1 diabetes mellitus in rats

  • Open Access

    ARTICLE

    MiR-520f-3p inhibits epithelial-mesenchymal transition of colorectal cancer cells by targeting Yes-associated protein 1

    LIJUN JIANG1, WENMIN JI1, YAJIE GONG2, JIAJUN LI2, JINCHUN LIU1,*

    BIOCELL, Vol.47, No.8, pp. 1803-1810, 2023, DOI:10.32604/biocell.2023.029516

    Abstract Background: Colorectal cancer (CRC) is one of the most common malignancies. Early diagnosis is the key to effective treatment of CRC. Since microRNAs (miRNAs) can be used as biomarkers of CRC, the objective of this work was to examine the effect of miR-520f-3p, which targets YAP1 (Yes-associated protein 1), on the ability of CRC cells to proliferate, invade, migrate, and undergo epithelial-mesenchymal transition (EMT). Methods: A miR-520f-3p mimic was used to overexpress miR-520f-3p in HT29 cells. To establish the tumor-bearing mouse model, transfected HT29 cells were subcutaneously implanted into BALB/c-nu nude mice, and YAP1 and miR-520f-3p levels were determined using… More > Graphic Abstract

    MiR-520f-3p inhibits epithelial-mesenchymal transition of colorectal cancer cells by targeting Yes-associated protein 1

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