K. Umapathi^1,*, S. Shobana¹, Anand Nayyar², Judith Justin³, R. Vanithamani³, Miguel Villagómez Galindo⁴, Mushtaq Ahmad Ansari⁵, Hitesh Panchal^6,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 1875-1901, 2024, DOI:10.32604/cmc.2024.047961

Abstract Breast cancer detection heavily relies on medical imaging, particularly ultrasound, for early diagnosis and effective treatment. This research addresses the challenges associated with computer-aided diagnosis (CAD) of breast cancer from ultrasound images. The primary challenge is accurately distinguishing between malignant and benign tumors, complicated by factors such as speckle noise, variable image quality, and the need for precise segmentation and classification. The main objective of the research paper is to develop an advanced methodology for breast ultrasound image classification, focusing on speckle noise reduction, precise segmentation, feature extraction, and machine learning-based classification. A unique approach is introduced that combines Enhanced… More >

Syed Ayaz Ali Shah^1,*, Aamir Shahzad^1,*, Musaed Alhussein², Chuan Meng Goh³, Khursheed Aurangzeb², Tong Boon Tang⁴, Muhammad Awais⁵

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2565-2583, 2024, DOI:10.32604/cmc.2024.047597

Abstract Diagnosing various diseases such as glaucoma, age-related macular degeneration, cardiovascular conditions, and diabetic retinopathy involves segmenting retinal blood vessels. The task is particularly challenging when dealing with color fundus images due to issues like non-uniform illumination, low contrast, and variations in vessel appearance, especially in the presence of different pathologies. Furthermore, the speed of the retinal vessel segmentation system is of utmost importance. With the surge of now available big data, the speed of the algorithm becomes increasingly important, carrying almost equivalent weightage to the accuracy of the algorithm. To address these challenges, we present a novel approach for retinal… More > Graphic Abstract

Norah Abdullah Al-Johany^1,*, Sanaa Abdullah Sharaf^1,2, Fathy Elbouraey Eassa^1,2, Reem Abdulaziz Alnanih^1,2,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3139-3173, 2024, DOI:10.32604/cmc.2024.047392

Abstract The Message Passing Interface (MPI) is a widely accepted standard for parallel computing on distributed memory systems. However, MPI implementations can contain defects that impact the reliability and performance of parallel applications. Detecting and correcting these defects is crucial, yet there is a lack of published models specifically designed for correcting MPI defects. To address this, we propose a model for detecting and correcting MPI defects (DC_MPI), which aims to detect and correct defects in various types of MPI communication, including blocking point-to-point (BPTP), nonblocking point-to-point (NBPTP), and collective communication (CC). The defects addressed by the DC_MPI model include illegal… More >

Muhammad Waqas Ahmed¹, Nouf Abdullah Almujally², Abdulwahab Alazeb³, Asaad Algarni⁴, Jeongmin Park^5,*

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 3315-3331, 2024, DOI:10.32604/cmc.2024.046501

Abstract Advances in machine vision systems have revolutionized applications such as autonomous driving, robotic navigation, and augmented reality. Despite substantial progress, challenges persist, including dynamic backgrounds, occlusion, and limited labeled data. To address these challenges, we introduce a comprehensive methodology to enhance image classification and object detection accuracy. The proposed approach involves the integration of multiple methods in a complementary way. The process commences with the application of Gaussian filters to mitigate the impact of noise interference. These images are then processed for segmentation using Fuzzy C-Means segmentation in parallel with saliency mapping techniques to find the most prominent regions. The… More >

Imad Saud Al Naimi^1,2,*, Syed Alwee Aljunid Syed Junid¹, Muhammad lmran Ahmad^1,*, K. Suresh Manic^2,3

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2585-2608, 2024, DOI:10.32604/cmc.2024.046461

Abstract Augmentation of abnormal cells in the brain causes brain tumor (BT), and early screening and treatment will reduce its harshness in patients. BT’s clinical level screening is usually performed with Magnetic Resonance Imaging (MRI) due to its multi-modality nature. The overall aims of the study is to introduce, test and verify an advanced image processing technique with algorithms to automatically extract tumour sections from brain MRI scans, facilitating improved accuracy. The research intends to devise a reliable framework for detecting the BT region in the two-dimensional (2D) MRI slice, and identifying its class with improved accuracy. The methodology for the… More >

Shalu¹, Twinkle Acharya¹, Dhwanilnath Gharekhan^1,*, Dipak Samal²

Revue Internationale de Géomatique, Vol.33, pp. 111-134, 2024, DOI:10.32604/rig.2024.051788

Abstract Seismic vulnerability modeling plays a crucial role in seismic risk assessment, aiding decision-makers in pinpointing areas and structures most prone to earthquake damage. While machine learning (ML) algorithms and Geographic Information Systems (GIS) have emerged as promising tools for seismic vulnerability modeling, there remains a notable gap in comprehensive geospatial studies focused on India. Previous studies in seismic vulnerability modeling have primarily focused on specific regions or countries, often overlooking the unique challenges and characteristics of India. In this study, we introduce a novel approach to seismic vulnerability modeling, leveraging ML and GIS to address these gaps. Employing Artificial Neural… More >

CHENG-GONG LUO^1,2,#, JIAO ZHANG^1,#, YUN-ZHAO AN¹, XUAN LIU¹, SHUAI-JIE LI¹, WEI ZHANG¹, KAI LI¹, XU ZHAO¹, DONG-BO YUAN¹, LING-YUE AN¹, WEI CHEN², YE TIAN^1,*, BIN XU^1,*

BIOCELL, Vol.48, No.5, pp. 771-792, 2024, DOI:10.32604/biocell.2024.048878

Abstract Background: Ferroptosis, a lipid peroxidation-mediated programmed cell death, is closely linked to tumor development, including prostate cancer (PCa). Despite established connections between ferroptosis and PCa, a comprehensive investigation is essential for understanding its impact on patient prognosis. Methods: A risk model incorporating four ferroptosis-related genes was developed and validated. Elevated risk scores correlated with an increased likelihood of biochemical recurrence (BCR), diminished immune infiltration, and adverse clinicopathological characteristics. To corroborate these results, we performed validation analyses utilizing datasets from both the Cancer Genome Atlas Cohort (TCGA) and the Gene Expression Synthesis Cohort (GEO). Moreover, we conducted further investigations into the… More >

YUANYUAN LI¹, BITAO ZHANG¹, ZILONG CUI¹, PEIJIAN FAN¹, SHAOXIAN WANG^1,2,*

BIOCELL, Vol.48, No.5, pp. 731-744, 2024, DOI:10.32604/biocell.2024.048820

Abstract Background: Depression is becoming increasingly prevalent around the world, imposing a substantial burden on individuals, families, as well as society. Quercetin is known to be highly effective in treating depression. However, additional research is needed to dissect the mechanisms of its anti-depressive effects. Methods: For this study, Sprague-Dawley (SD) rats were randomized into the control, model, quercetin, or fluoxetine group. The latter three groups were exposed to chronic unpredictable mild stress (CUMS) for 42 d. The first two groups received saline solution daily via oral gavage. Meanwhile, the quercetin group was orally administered a quercetin suspension (52.08 mg/kg) every day,… More >

XINRU FENG¹, LI XIAO^2,*

BIOCELL, Vol.48, No.5, pp. 793-801, 2024, DOI:10.32604/biocell.2024.048395

Abstract Background: Galectin 2 (LGALS2) is a protein previously reported to serve as a mediator of disease progression in a range of cancers. The function of LGALS2 in oral squamous cell carcinoma (OSCC), however, has yet to be explored, prompting the present study to address this literature gap. Methods: Overall, 144 paired malignant tumor tissues and paracancerous OSCC patient samples were harvested and the LGALS2 expression levels were examined through qPCR and western immunoblotting. The LGALS2 coding sequence was introduced into the pcDNA3.0 vector, to enable the overexpression of this gene, while an LGALS2-specific shRNA and corresponding controls were also obtained.… More >

JING HUI^1,2, NANA SUN³, YONG LIU⁴, CHUNBO YU^1,2, YONG KE⁴, YONG CAO⁴, ANXIAO YU⁴, QINGHONG KONG^1,2,*, YUN LIU^1,2,4,*

BIOCELL, Vol.48, No.5, pp. 803-815, 2024, DOI:10.32604/biocell.2024.047122

Abstract Background: Although it has been established that the human Solute Carrier Family 22 (SLC22) functions as a cationic transporter, influencing cellular biological metabolism by modulating the uptake of various cations, its impact on cancer prognosis remains unclear. Methods: We conducted a comprehensive analysis utilizing data from The Cancer Genome Atlas (TCGA) and other databases to assess the prognostic value and functional implications across various tumors. Silence of SLC22A1 RNA in glioma U251 cells was performed to access the impact of SLC22A1 on lower-grade glioma (LGG) progression. Results: Our findings demonstrated a significant correlation between SLC22A1 expression and the survival time… More >