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  • Open Access

    ARTICLE

    Finite Element Simulations of the Localized Failure and Fracture Propagation in Cohesive Materials with Friction

    Chengbao Hu1,2,3, Shilin Gong4,*, Bin Chen1,2,3, Zhongling Zong4, Xingwang Bao5, Xiaojian Ru5

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 997-1015, 2024, DOI:10.32604/cmes.2024.048640

    Abstract Strain localization frequently occurs in cohesive materials with friction (e.g., composites, soils, rocks) and is widely recognized as a fundamental cause of progressive structural failure. Nonetheless, achieving high-fidelity simulation for this issue, particularly concerning strong discontinuities and tension-compression-shear behaviors within localized zones, remains significantly constrained. In response, this study introduces an integrated algorithm within the finite element framework, merging a coupled cohesive zone model (CZM) with the nonlinear augmented finite element method (N-AFEM). The coupled CZM comprehensively describes tension-compression and compression-shear failure behaviors in cohesive, frictional materials, while the N-AFEM allows nonlinear coupled intra-element discontinuities without necessitating extra nodes or… More >

  • Open Access

    ARTICLE

    Research on Anti-Fluctuation Control of Winding Tension System Based on Feedforward Compensation

    Yujie Duan1, Jianguo Liang1,*, Jianglin Liu1, Haifeng Gao1, Yinhui Li2, Jinzhu Zhang1, Xinyu Wen3

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 1239-1261, 2024, DOI:10.32604/cmes.2023.044400

    Abstract In the fiber winding process, strong disturbance, uncertainty, strong coupling, and fiber friction complicate the winding constant tension control. In order to effectively reduce the influence of these problems on the tension output, this paper proposed a tension fluctuation rejection strategy based on feedforward compensation. In addition to the bias harmonic curve of the unknown state, the tension fluctuation also contains the influence of bounded noise. A tension fluctuation observer (TFO) is designed to cancel the uncertain periodic signal, in which the frequency generator is used to estimate the critical parameter information. Then, the fluctuation signal is reconstructed by a… More >

  • Open Access

    CASE REPORT

    Pulmonary Hypertension Crisis in Patient with Tetralogy of Fallot and Mixed Total Anomalous Pulmonary Vein Connection after the Primary Correction: A Rare Case Report

    Dian Kesumarini1,2, Yunita Widyastuti3, Cindy Elfira Boom1, Lucia Kris Dinarti4,*

    Congenital Heart Disease, Vol.18, No.6, pp. 671-678, 2023, DOI:10.32604/chd.2023.044746

    Abstract Tetralogy of Fallot (TOF) with total anomalous pulmonary vein connections (TAPVC) is a rare type of complex congenital heart disease among all TOF cases. Co-presentation of major aortopulmonary collateral arteries (MAPCAs) compensates for the lack of central pulmonary blood flow and decreases the severity of right-to-left shunting in TOF. We present a case of a 2-year-old child with complex diagnoses of TOF, TAPVC, a large secundum atrial septal defect (ASD), and intraoperatively identified MAPCAs. She underwent surgery to repair the TAPVC, valve-sparing reconstruction of the right ventricular outflow tract, interventricular defect closure, and the creation of patent foramen ovale (PFO).… More >

  • Open Access

    ARTICLE

    Wellbore Cleaning Degree and Hydraulic Extension in Shale Oil Horizontal Wells

    Xin Ai1,2,*, Mian Chen1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.3, pp. 661-670, 2024, DOI:10.32604/fdmp.2023.026819

    Abstract

    The efficient development and exploitation of shale oil depends on long-distance horizontal wells. As the degree of cleaning of the wellbore plays a key role in these processes, in this study, this problem is investigated experimentally by focusing on the dimensionless cuttings bed height. A method is proposed to calculate the horizontal-well hydraulic extension taking into account the influence of the wellbore cleaning degree on the wellbore pressure distribution and assess the effect of a variety of factors such as the bottom hole pressure, the circulating pressure drop, the drilling pump performance and the formation properties. The analysis shows that… More >

  • Open Access

    ARTICLE

    Dynamics along the epithelial-cancer biointerface: Hidden system complexities

    IVANA PAJIC-LIJAKOVIC*, MILAN MILIVOJEVIC

    BIOCELL, Vol.47, No.11, pp. 2321-2334, 2023, DOI:10.32604/biocell.2023.043796

    Abstract The biointerface dynamics influence any cancer spreading through the epithelium since it is documented in the early stages some malignancies (like epithelial cancer). The altered rearrangement of epithelial cells has an impact on the development of cancer. Therefore, it is necessary to comprehend the underlying biological and physical mechanisms of this biointerface dynamics for early suppression of cancer. While the biological mechanisms include cell signaling and gene expression, the physical mechanisms are several physical parameters such as the epithelial-cancer interfacial tension, epithelial surface tension, and compressive stress accumulated within the epithelium. Although the segregation of epithelia-cancer co-cultured systems was widely… More > Graphic Abstract

    Dynamics along the epithelial-cancer biointerface: Hidden system complexities

  • Open Access

    ARTICLE

    NR4A1 enhances glycolysis in hypoxia-exposed pulmonary artery smooth muscle cells by upregulating HIF-1α expression

    CHENYANG CHEN1,*, JUAN WEN1, WEI HUANG1, JIANG LI2,*

    BIOCELL, Vol.47, No.11, pp. 2423-2433, 2023, DOI:10.32604/biocell.2023.044459

    Abstract Background: Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that is strongly associated with dysregulation of glucose metabolism. Alterations in nuclear receptor subfamily 4 group A member 1 (NR4A1) activity alter the outcome of PAH. This study aimed to investigate the effects of NR4A1 on glycolysis in PAH and its underlying mechanisms. Methods: This study included twenty healthy volunteers and twenty-three PAH patients, and plasma samples were collected from the participants. To mimic the conditions of PAH in vitro, a hypoxia-induced model of pulmonary artery smooth muscle cell (PASMC) model was established. The proliferation of PASMCs was assessed… More > Graphic Abstract

    NR4A1 enhances glycolysis in hypoxia-exposed pulmonary artery smooth muscle cells by upregulating HIF-1α expression

  • Open Access

    PROCEEDINGS

    A Data-Fusion Method for Uncertainty Quantification of Mechanical Property of Bi-Modulus Materials: An Example of Graphite

    Liang Zhang1,*, Zigang He1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.09713

    Abstract The different elastic properties of tension and compression are obvious in many engineering materials, especially new materials. Materials with this characteristic, such as graphite, ceramics, and composite materials, are called bi-modulus materials. Their mechanical properties such as Young’s modulus have randomness in tension and compression due to different porosity, microstructure, etc. To calibrate the mechanical properties of bi-modulus materials by bridging FEM simulation results and scarce experimental data, the paper presents a data-fusion computational method. The FEM simulation is implemented based on Parametric Variational Principle (PVP), while the experimental result is obtained by Digital Image Correlation (DIC) technology. To deal… More >

  • Open Access

    PROCEEDINGS

    Extension of Ordinary State-Based Peridynamic Model for Nonlinear Analysis

    Mengnan Zhang1,*, Fucheng Tian1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09593

    Abstract Peridynamic is a nonlocal theory that uses integral forms of governing equations, making it suitable for describing objects with discontinuous states such as cracks. After more than two decades of development, peridynamic has been effectively applied to numerous solid mechanics studies. However, in the field of ordinary state-based peridynamic modeling nonlinear deformation, a more comprehensive model that can establish a general connection with continuum mechanics and allow for the selection of different influence functions is still lacking. As a consequence, a further extension to existing models is promising, and it represents a substantial addition to the current peridynamic model. In… More >

  • Open Access

    PROCEEDINGS

    Identification of Constitutive Parameters for the Non-Local Damage Model of Soft Biological Tissues

    Taotao Yuan1, Haitian Yang1, Yiqian He1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09275

    Abstract Computational modeling can provide insight into understanding the damage mechanisms of soft biological tissues, and identification of constitutive parameters is key issues in the computational modeling. On the other hand, although it is thought that computational model should be non-local for soft tissues based on the existence of intrinsic length scales, there is very few work for the identification of the parameters of nonlocal damage models of soft tissues. Firstly, we use the gradient-enhanced damage model presented in our previous publication showing advantages in considering the internal length scales and in satisfying mesh independence for simulating damage [1]. Secondly, the… More >

  • Open Access

    PROCEEDINGS

    A Crystal Plasticity Based Constitutive Model for the Temperature Dependent Anomalous Behaviors of Nickel-Based Single-Crystal Superalloy

    Xueling Fan1,*, Pin Lu1, Xiaochao Jin1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.09919

    Abstract Ni-based single crystal superalloys have been favored in the high-temperature service zones of aeroengine and gas turbine due to its excellent mechanical properties at high temperature. It is very significant to construct a constitutive model that can accurately capture the mechanical response of Ni-based single crystals for simulation analysis. In this work, a forest dislocation density-based single crystal plasticity constitutive model was developed to capture the mechanical behavior of Ni-based single crystals, including the temperature dependent anomalous yield and tension/compression asymmetry. Firstly, thermally activated cross-slip mechanism was introduced into the hardening model to describe the anomalous yield response. Secondly, the… More >

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