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  • Open Access

    ARTICLE

    Research on Deformation Mechanism of Rolled AZ31B Magnesium Alloy during Tension by VPSC Model Computational Simulation

    Xun Chen1, Jinbao Lin1,2,*, Zai Wang1

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072495 - 12 January 2026

    Abstract This work investigates the effects of deformation mechanisms on the mechanical properties and anisotropy of rolled AZ31B magnesium alloy under uniaxial tension, combining experimental characterization with Visco-Plastic Self Consistent (VPSC) modeling. The research focuses particularly on anisotropic mechanical responses along transverse direction (TD) and rolling direction (RD). Experimental measurements and computational simulations consistently demonstrate that prismatic <a> slip activation significantly reduces the strain hardening rate during the initial stage of tensile deformation. By suppressing the activation of specific deformation mechanisms along RD and TD, the tensile mechanical behavior of the magnesium alloy was further investigated. More >

  • Open Access

    REVIEW

    Endothelial and Mitochondrial Dysfunction in COPD Pathophysiology: Focus on Homocysteine–L-Carnitine Interplay

    Eduard Belskikh1,*, Yuliya Marsyanova2, Denis Melnikov3, Oleg Uryasev1, Valentina Zvyagina2

    BIOCELL, Vol.49, No.11, pp. 2093-2123, 2025, DOI:10.32604/biocell.2025.069272 - 24 November 2025

    Abstract Elevated homocysteine is a clinically relevant metabolic signal in chronic obstructive pulmonary disease (COPD). Higher circulating levels track with oxidative stress, endothelial dysfunction, mitochondrial impairment, and pulmonary vascular remodeling, rise with disease severity, and may contribute to the excess cardiovascular risk—although effect sizes and causality remain uncertain. This review centers on the homocysteine–carnitine relationship in COPD pathophysiology. Carnitine deficiency, prevalent in COPD, can worsen mitochondrial bioenergetics, promote accumulation of acyl intermediates, and reduce nitric oxide bioavailability via endothelial nitric oxide synthase uncoupling (eNOS). Conversely, restoring carnitine status in experimental and early clinical settings has been… More >

  • Open Access

    CASE REPORT

    A case report of epithelioid renal angiomyolipoma with inferior vena cava extension: robotic surgical management and literature review of rare presentation

    Dimindra Karki*, Ghizlane Yaakoubi, Beth Edelblute, Ahmed Aboumohamed*

    Canadian Journal of Urology, Vol.32, No.5, pp. 501-507, 2025, DOI:10.32604/cju.2025.063294 - 30 October 2025

    Abstract Background: Epithelioid angiomyolipoma (EAML) is an uncommon renal tumor variant with histologic and radiologic features that can mimic renal cell carcinoma (RCC) on imaging due to the paucity of fat compared to the classic AML. EAML may exhibit aggressive behavior, including local invasion, recurrence, and distant metastases to the liver, lungs, and lymph nodes. Although recent reports suggest that up to one-third of EAML cases may behave malignantly, variability in diagnostic criteria and limited case series contribute to uncertainty regarding its true clinical course. Case Description: This case report describes a 19-year-old female presenting with an… More >

  • Open Access

    ARTICLE

    Shallow Water Waves with Surface Tension by Laplace–Adomian Decomposition

    Oswaldo González-Gaxiola1, Yakup Yildirim2,3,4, Luminita Moraru5,6, Anjan Biswas7,8,9,10,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.9, pp. 2273-2287, 2025, DOI:10.32604/fdmp.2025.067959 - 30 September 2025

    Abstract This study presents a numerical investigation of shallow water wave dynamics with particular emphasis on the role of surface tension. In the absence of surface tension, shallow water waves are primarily driven by gravity and are well described by the classical Boussinesq equation, which incorporates fourth-order dispersion. Under this framework, solitary and shock waves arise through the balance of nonlinearity and gravity-induced dispersion, producing waveforms whose propagation speed, amplitude, and width depend largely on depth and initial disturbance. The resulting dynamics are comparatively smoother, with solitary waves maintaining coherent structures and shock waves displaying gradual… More > Graphic Abstract

    Shallow Water Waves with Surface Tension by Laplace–Adomian Decomposition

  • Open Access

    PROCEEDINGS

    Research on the Vertical Fracture Propagation Behavior of Deep Offshore Sandstone Reservoirs

    Weishuai Zhang, Fengjiao Wang, Yikun Liu*, Yilin Liu

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.010789

    Abstract The mechanism of vertical extension in high-volume hydraulic fracturing is of significant importance for the volumetric transformation of low-permeability reservoirs in deep offshore sandstone formations. The complexity of fracture propagation behavior is influenced by the characteristics of discontinuous thin layers in the vertical plane. However, the mechanisms and influencing factors of fracture extension in the vertical direction during high-volume hydraulic fracturing remain unclear. This study integrates true triaxial hydraulic fracturing experiments with acoustic emission (AE) monitoring, employing a nonlinear finite element method to establish a multi-thin interlayer fracturing model based on seepage-stress-damage coupling. It investigates… More >

  • Open Access

    ARTICLE

    A New Extension Odd Generalized Exponential Model Using Type-II Progressive Censoring and Its Applications in Engineering and Medicine

    Zohra A. Esaadi1, Rabab S. Gomaa1, Beih S. El-Desouky1, Ehab M. Almetwally2, Alia M. Magar1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2063-2097, 2025, DOI:10.32604/cmes.2025.065604 - 31 August 2025

    Abstract A new extended distribution called the Odd Exponential Generalized Exponential-Exponential distribution is proposed based on generalization of the odd generalized exponential family (OEGE-E). The statistical properties of the proposed distribution are derived. The study evaluates the accuracy of six estimation methods under complete samples. Estimation techniques include maximum likelihood, ordinary least squares, weighted least squares, maximum product of spacing, Cramer von Mises, and Anderson-Darling methods. Two methods of estimation for the involved parameters are considered based on progressively type II censored data (PTIIC). These methods are maximum likelihood and maximum product of spacing. The proposed More >

  • Open Access

    REVIEW

    Pulmonary Hypertension Associated with Congenital Heart Disease: A Clinical Primer

    Lily M. Landry1,*, Christopher L. Jenks2

    Congenital Heart Disease, Vol.20, No.3, pp. 325-339, 2025, DOI:10.32604/chd.2025.066142 - 11 July 2025

    Abstract Pulmonary hypertension associated with congenital heart disease represents a significant challenge for clinicians due to its complex pathophysiology and diverse presentation. This patient population exhibits a broad spectrum of anatomical and hemodynamic abnormalities, with congenital heart disease-associated pulmonary arterial hypertension (PAH-CHD) comprising a significant proportion of pediatric pulmonary hypertension (PH) cases. Although progress in diagnostic methods and treatment options has been made, PH continues to be a major contributor to illness and death among affected pediatric patients, especially when diagnosis or treatment is postponed. This review aims to equip non-specialist clinicians with a better understanding More >

  • Open Access

    ARTICLE

    Hemodynamic Profile Based on Right Heart Catheterization in Adult Acyanotic Congenital Heart Disease with Pulmonary Hypertension

    Dina Anggraini1, Kurnia Wahyudi2, Melawati Hasan3, Sri Endah Rahayuningsih4,*, Charlotte Johanna Cool3

    Congenital Heart Disease, Vol.20, No.2, pp. 133-141, 2025, DOI:10.32604/chd.2025.064164 - 30 April 2025

    Abstract Background: Congenital heart disease (CHD) occurs in 9 out of 100 births and is the leading cause of birth defects, with acyanotic CHD being more common. The incidence of adult CHD is rising faster than pediatric CHD. Pulmonary hypertension is the most common complication in untreated CHD patients. Methods: This study is retrospective descriptive research based on medical record data and the results of right heart catheterization examinations in adult acyanotic CHD aged ≥18 years and free from other organ disorders. Results: A total of 103 patients met the inclusion criteria, the majority were young… More >

  • Open Access

    ARTICLE

    Effect of Surface Tension on the Dynamics of an Oscillating Interface in a Vertical Slotted Channel

    Veronika Dyakova1,2,*, Olga Vlasova1, Victor Kozlov1

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.3, pp. 493-508, 2025, DOI:10.32604/fdmp.2025.060577 - 01 April 2025

    Abstract An experimental investigation of the dynamics of the interface between two low-viscosity fluids with high density contrast oscillating in a fixed vertical slotted channel has been conducted. It has been found that as the amplitude of the liquid column oscillations increases, parametric oscillations of the interface are excited in the form of a standing wave located in the channel plane. In particular, depending on the interfacial tension, the standing waves have a frequency equal to that of liquid piston oscillations (harmonic response), or half of the frequency of oscillations of the liquid column in the… More >

  • Open Access

    REVIEW

    Reverse Potts Shunt in Children with Suprasystemic Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

    Yong An1,2, Gang Wang1,2, Jiangtao Dai1,2, Zhengxia Pan1,2, Yuhao Wu1,2,*

    Congenital Heart Disease, Vol.20, No.1, pp. 1-12, 2025, DOI:10.32604/chd.2025.063152 - 18 March 2025

    Abstract Background Pulmonary arterial hypertension (PAH) is a progressive condition with a poor prognosis in children. Lung transplantation (Ltx) remains the ultimate option when patients are refractory to PAH-specific therapy. Reverse Potts shunt (RPS) has been introduced to treat suprasystemic PAH. This study aims to investigate the clinical outcomes of suprasystemic PAH in children. Methods Embase, Pubmed, and the Cochrane Library databases were searched for related studies that reported the clinical outcomes of suprasystemic PAH following RPS in children. To investigate the clinical outcomes of RPS, meta-analyses of the early and overall mortalities were performed. Results Nine studies… More >

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