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  • Open Access

    REVIEW

    The Potential of Circular RNAs as Biomarkers in Pulmonary Arterial Hypertension Related to Congenital Heart Disease

    Fajri Marindra Siregar1,2, Sofia Mubarika Haryana3, Dyah Wulan Anggrahini4, Lucia Kris Dinarti4, Anggoro Budi Hartopo4,*

    Congenital Heart Disease, Vol.19, No.4, pp. 375-388, 2024, DOI:10.32604/chd.2024.054742 - 31 October 2024

    Abstract A particular type of endogenous noncoding RNAs known as circular RNAs (circRNAs) has now become possible biomarkers for several diseases because of their stability and tissue-specific expression patterns. CircRNAs might play a role in various of biological processes. The identification of particular circRNAs dysregulated in pulmonary arterial hypertension (PAH) raises the possibility of these molecules serving as biomarkers for the disease’s early diagnosis and treatment. This review mainly summarizes the role and potential of circRNA as a future biomarker in PAH related to congenital heart disease. This study presented several potential circRNA targets as diagnostic More > Graphic Abstract

    The Potential of Circular RNAs as Biomarkers in Pulmonary Arterial Hypertension Related to Congenital Heart Disease

  • Open Access

    ARTICLE

    Assessment of Operational Performance in a Power Generation/Selling Integrated Company Using a Dynamic Proportional Adjustment Coefficient

    Jingbin Wu1,*, Hongming Yang2, Sheng Xiang2

    Energy Engineering, Vol.121, No.11, pp. 3263-3287, 2024, DOI:10.32604/ee.2024.054019 - 21 October 2024

    Abstract Currently, the operational performance assessment system in the power market primarily focuses on power generation and electricity retail companies, lacking a system tailored to the operational characteristics of power generation/selling integrated companies. Therefore, this article proposes an assessment index system for assessing the operational performance of a power generation/selling integrated company, encompassing three dimensions: basic capacity, development potential, and external environment. A dynamic proportional adjustment coefficient is designed, along with a subjective and objective weighting model for assessment indexes based on a combined weighting method. Subsequently, the operational performance of an integrated company is assessed More > Graphic Abstract

    Assessment of Operational Performance in a Power Generation/Selling Integrated Company Using a Dynamic Proportional Adjustment Coefficient

  • Open Access

    PROCEEDINGS

    Tension, Shear and Bending Properties of Two-Dimensional Materials

    Hongfei Ye1,*, Dong Li1,2, Hongwu Zhang1, Yonggang Zheng1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.010938

    Abstract Due to excellent physical performance and potential application in the nanoscale fluid channel, 2D transition-metal dioxides and dichalcogenides with 1H phase are of great interest. Their mechanical property attracts much attention but the accurate evaluation still faces challenges because of the ultrasoft and ultrathin structure. In this work, we establish an analytical atom-based molecular mechanics model to predict the elastic modulus, Poisson’s ratio and shear modulus of the single-layer 2D transition-metal dioxides and dichalcogenides. The proposed method is validated through the calculation of the mechanical property of Molybdenum disulfide (MoS2). The results indicate that the elastic… More >

  • Open Access

    PROCEEDINGS

    A Phase Field Model for the Fracture of Micropolar Medium Considering the Tension-Torsion Coupling Effect

    Hongjun Yu1,*, Canjie Huang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011454

    Abstract A novel and irreversible phase field model accounting for tension-torsion coupling effect and size-effect is constructed in the context of continuum thermodynamics. First, a general framework considering the energy dissipation process influenced by micro and macro force is formulated according to thermodynamically consistent derivation. Next, the framework is specialized by introducing a material parameter called chiral coefficient to characterize the tension-torsion coupling effect within macro force constitutive according to isotropic micropolar elasticity theory. To gain insight of the chiral effect on the fracture behaviors, the analytical solution of uniaxial traction chiral rod is provided based More >

  • Open Access

    ARTICLE

    Enhancing the Shelf Life of Edible Musa Acuminate with Biopolymer Coating

    Manivasagam Vishwa Rohini1,#, Sathish Kiruba1, Danniel Santhanaraj1, Prakash Priyanka Nair1, P. Sudhakara2,*, Jujhar Singh3, Balamurugan Rathinam4,*, Vanaraj Ramkumar5,6,#

    Journal of Polymer Materials, Vol.41, No.3, pp. 159-178, 2024, DOI:10.32604/jpm.2024.054801 - 30 September 2024

    Abstract The Cavendish banana, Musa acuminata, is a climacteric fruit that ripens quickly after harvest. Due to their high perishability and susceptibility to disease, bananas have substantial postharvest losses. After harvesting, it is important to extend the bananas’ shelf life. Unique coating gel solutions based on glycerol and ascorbic acid were developed to accomplish this. Chitosan mixed with glacial acetic acid, lactic acid, and sodium alginate were among the gel solutions in these combinations. The goal was to improve banana preservation while maintaining freshness and quality by implementing innovative formulations and techniques. The fruits are hand-dried and… More >

  • Open Access

    ARTICLE

    Droplet Condensation and Transport Properties on Multiple Composite Surface: A Molecular Dynamics Study

    Haowei Hu1,2,*, Qi Wang1, Xinnuo Chen1, Qin Li3, Mu Du4, Dong Niu5,*

    Frontiers in Heat and Mass Transfer, Vol.22, No.4, pp. 1245-1259, 2024, DOI:10.32604/fhmt.2024.054223 - 30 August 2024

    Abstract To investigate the microscopic mechanism underlying the influence of surface-chemical gradient on heat and mass recovery, a molecular dynamics model including droplet condensation and transport process has been developed to examine heat and mass recovery performance. This work aimed at identify optimal conditions for enhancing heat and mass recovery through the combination of wettability gradient and nanopore transport. For comprehensive analysis, the structure in the simulation was categorized into three distinct groups: a homogeneous structure, a small wettability gradient, and a large wettability gradient. The homogeneous surface demonstrated low efficiency in heat and mass transfer, More >

  • Open Access

    ARTICLE

    Fish Gelatin-Based Film Containing Maillard Reaction Products: Properties and Its Use as Bag for Packing Chicken Skin Oil

    Krisana Nilsuwan1,*, Yolanda Victoria Rajagukguk2, Umesh Patil1, Thummanoon Prodpran1,3, Soottawat Benjakul1,4,*

    Journal of Renewable Materials, Vol.12, No.6, pp. 1125-1143, 2024, DOI:10.32604/jrm.2024.051361 - 02 August 2024

    Abstract Maillard reaction is a non-enzymatic browning reaction and its products (MRPs) have been proven to possess antioxidant properties. This research aimed to produce a fish gelatin-based packaging incorporated with MRPs to retard lipid oxidation in chicken skin oil (CSO) during storage at ambient temperature (28°C–30°C). MRPs produced from fish gelatin and fructose (1:1, 90°C, pH 11) showed the highest antioxidant properties compared to those prepared under other conditions. Different glycerol/MRPs ratios (30:0, 25:5, 20:10, 15:15, 10:20, 5:25, 0:30) were incorporated into the film and resulting films were characterized. Glycerol/MRPs at 10:20 ratio was chosen to… More > Graphic Abstract

    Fish Gelatin-Based Film Containing Maillard Reaction Products: Properties and Its Use as Bag for Packing Chicken Skin Oil

  • Open Access

    ARTICLE

    Risk Stratification and Prognosis of Pulmonary Arterial Hypertension Associated with Congenital Heart Disease

    Wenjie Dong1,2,#, Zhibin Hong1,#, Aqian Wang2, Kaiyu Jiang2, Hai Zhu2, Fu zhang2, Zhaoxia Guo2, Hongling Su2,*, Yunshan Cao3,*

    Congenital Heart Disease, Vol.19, No.3, pp. 325-339, 2024, DOI:10.32604/chd.2024.052267 - 26 July 2024

    Abstract Background: Current guidelines for managing pulmonary arterial hypertension (PAH) recommend a risk stratification approach. However, the applicability and accuracy of these strategies for PAH associated with congenital heart disease (PAH-CHD) require further validation. This study aims to validate the reliability and predictive accuracy of a simplified stratification strategy for PAH-CHD patients over a three-year follow-up. Additionally, new prognostic variables are identified and novel risk stratification methods are developed for assessing and managing PAH-CHD patients. Methods: This retrospective study included 126 PAH-CHD patients. Clinical and biochemical variables across risk groups were assessed using Kruskal-Wallis and Fisher’s… More > Graphic Abstract

    Risk Stratification and Prognosis of Pulmonary Arterial Hypertension Associated with Congenital Heart Disease

  • Open Access

    ARTICLE

    Reliability of Echocardiographic Pulmonary Vascular Resistance to Screen for the New Definition of Precapillary Pulmonary Hypertension in Uncorrected Secundum Atrial Septal Defect

    Risalina Myrtha1,2,*, Hasanah Mumpuni3,4, Real Kusumanjaya Marsam3,4, Dyah Wulan Anggrahini3,4, Anggoro Budi Hartopo3,4, Lucia Kris Dinarti3,4

    Congenital Heart Disease, Vol.19, No.3, pp. 315-324, 2024, DOI:10.32604/chd.2024.051587 - 26 July 2024

    Abstract Background and Objective: The most feared complication of uncorrected secundum Atrial Septal Defect (ASD) is pulmonary arterial hypertension (PAH). Pulmonary vascular resistance (PVR) is crucial in detecting precapillary pulmonary hypertension (PH) to guide the need for PAH-specific therapy. There is a change in the cut-off value of PVR according to the recently updated PH guideline. How echocardiographic PVR (PVR) correlates to PVR by right heart catheterization (RHC) (PVR) according to the new guidelines has not been known. The aim of this study is to determine the reliability of PVR in detecting PAH in Uncorrected Ostium… More > Graphic Abstract

    Reliability of Echocardiographic Pulmonary Vascular Resistance to Screen for the New Definition of Precapillary Pulmonary Hypertension in Uncorrected Secundum Atrial Septal Defect

  • Open Access

    ARTICLE

    Experimental Study on the Bubble Dynamics of Magnetized Water Boiling

    Yang Cao1,*, Jianshu Liu2, Xuhui Meng1

    Frontiers in Heat and Mass Transfer, Vol.22, No.2, pp. 675-685, 2024, DOI:10.32604/fhmt.2024.051208 - 20 May 2024

    Abstract Boiling heat transfer, as an efficient heat transfer approach, that can absorb a large amount of latent heat during the vaporization, is especially suitable for heat transfer occasions with high heat flux demands. Experimental studies show that the surface tension coefficient of pure water can be reduced sharply (up to 25%) when it is magnetized by a magnetic field applied externally. In this paper, magnetized water (MW) was used as the work fluid to conduct boiling heat transfer experiments, to explore the influence of magnetization on the boiling characteristics of pure water. The electromagnetic device… More >

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