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  • Open Access

    REVIEW

    Reverse Potts Shunt in Children with Suprasystemic Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

    Yong An1,2, Gang Wang1,2, Jiangtao Dai1,2, Zhengxia Pan1,2, Yuhao Wu1,2,*

    Congenital Heart Disease, Vol.20, No.1, pp. 1-12, 2025, DOI:10.32604/chd.2025.063152 - 18 March 2025

    Abstract Background Pulmonary arterial hypertension (PAH) is a progressive condition with a poor prognosis in children. Lung transplantation (Ltx) remains the ultimate option when patients are refractory to PAH-specific therapy. Reverse Potts shunt (RPS) has been introduced to treat suprasystemic PAH. This study aims to investigate the clinical outcomes of suprasystemic PAH in children. Methods Embase, Pubmed, and the Cochrane Library databases were searched for related studies that reported the clinical outcomes of suprasystemic PAH following RPS in children. To investigate the clinical outcomes of RPS, meta-analyses of the early and overall mortalities were performed. Results Nine studies… More >

  • Open Access

    REVIEW

    Smoothed Particle Hydrodynamics (SPH) Simulations of Drop Evaporation: A Comprehensive Overview of Methods and Applications

    Leonardo Di G. Sigalotti*, Carlos A. Vargas

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.3, pp. 2281-2337, 2025, DOI:10.32604/cmes.2025.060497 - 03 March 2025

    Abstract The evaporation of micrometer and millimeter liquid drops, involving a liquid-to-vapor phase transition accompanied by mass and energy transfer through the liquid-vapor interface, is encountered in many natural and industrial processes as well as in numerous engineering applications. Therefore, understanding and predicting the dynamics of evaporating flows have become of primary importance. Recent efforts have been addressed using the method of Smoothed Particle Hydrodynamics (SPH), which has proven to be very efficient in correctly handling the intrinsic complexity introduced by the multiscale nature of the evaporation process. This paper aims to provide an overview of… More > Graphic Abstract

    Smoothed Particle Hydrodynamics (SPH) Simulations of Drop Evaporation: A Comprehensive Overview of Methods and Applications

  • Open Access

    ARTICLE

    A Dynamic Prediction Approach for Wire Icing Thickness under Extreme Weather Conditions Based on WGAN-GP-RTabNet

    Mingguan Zhao1,2,*, Xinsheng Dong1,2, Yang Yang1,2, Meng Li1,2, Hongxia Wang1,2, Shuyang Ma1,2, Rui Zhu3, Xiaojing Zhu3

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.2, pp. 2091-2109, 2025, DOI:10.32604/cmes.2025.059169 - 27 January 2025

    Abstract Ice cover on transmission lines is a significant issue that affects the safe operation of the power system. Accurate calculation of the thickness of wire icing can effectively prevent economic losses caused by ice disasters and reduce the impact of power outages on residents. However, under extreme weather conditions, strong instantaneous wind can cause tension sensors to fail, resulting in significant errors in the calculation of icing thickness in traditional mechanics-based models. In this paper, we propose a dynamic prediction model of wire icing thickness that can adapt to extreme weather environments. The model expands… More >

  • Open Access

    ARTICLE

    Medical Diagnosis Based on Multi-Attribute Group Decision-Making Using Extension Fuzzy Sets, Aggregation Operators and Basic Uncertainty Information Granule

    Anastasios Dounis*, Ioannis Palaiothodoros, Anna Panagiotou

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.1, pp. 759-811, 2025, DOI:10.32604/cmes.2024.057888 - 17 December 2024

    Abstract Accurate medical diagnosis, which involves identifying diseases based on patient symptoms, is often hindered by uncertainties in data interpretation and retrieval. Advanced fuzzy set theories have emerged as effective tools to address these challenges. In this paper, new mathematical approaches for handling uncertainty in medical diagnosis are introduced using q-rung orthopair fuzzy sets (q-ROFS) and interval-valued q-rung orthopair fuzzy sets (IVq-ROFS). Three aggregation operators are proposed in our methodologies: the q-ROF weighted averaging (q-ROFWA), the q-ROF weighted geometric (q-ROFWG), and the q-ROF weighted neutrality averaging (q-ROFWNA), which enhance decision-making under uncertainty. These operators are paired More > Graphic Abstract

    Medical Diagnosis Based on Multi-Attribute Group Decision-Making Using Extension Fuzzy Sets, Aggregation Operators and Basic Uncertainty Information Granule

  • Open Access

    ARTICLE

    Bending Stiffness of Concrete-Filled Steel Tube and Its Influence on Concrete Placement Timing of Composite Beam-String Structure

    Zhenyu Zhang1, Quan Jin1, Haitao Zhang1, Zhao Liu1, Yuyang Wu2, Longfei Zhang2, Renzhang Yan2,*

    Structural Durability & Health Monitoring, Vol.19, No.1, pp. 167-191, 2025, DOI:10.32604/sdhm.2024.053190 - 15 November 2024

    Abstract When the upper chord beam of the beam-string structure (BSS) is made of concrete-filled steel tube (CFST), its overall stiffness will change greatly with the construction of concrete placement, which will have an impact on the design of the tensioning plans and selection of control measures for the BSS. In order to accurately obtain the bending stiffness of CFST beam and clarify its impact on the mechanical properties of composite BSS during construction, the influence of some factors such as height-width ratio, wall thickness of steel tube, elasticity modulus of concrete, and friction coefficient on More >

  • Open Access

    ARTICLE

    Discrete Numerical Study on Type II Fracture of Partially Detached Concrete Panels in Cold Region

    Huayi Zhang1, Maobin Song2, Lei Shen1,*, Nizar Faisal Alkayem1, Maosen Cao3

    Structural Durability & Health Monitoring, Vol.19, No.1, pp. 55-75, 2025, DOI:10.32604/sdhm.2024.052869 - 15 November 2024

    Abstract The concrete panel of earth-rock dams in cold regions tends to crack due to the combination effect of non-uniform foundation settlement, ice expansion loads, and freeze-thaw damage. In this work, simulations are designed to investigate the effects of freeze-thaw damage degrees on the fracture behavior caused by the partial detachment and ice expansion loads on concrete panels. Results show that the range of detached panels and freeze-thaw damage degree are the dominant factors that affect the overall load-bearing capacity of the panel and the failure cracking modes, whereas the panel slope is a secondary factor. More >

  • Open Access

    REVIEW

    Side effect management algorithms for niraparib/abiraterone acetate in prostate cancer

    Jean-Baptiste Lattouf1, Jenny J. Ko2, Margot K. Davis3, Christian Constance4, Geoffrey T. Gotto5

    Canadian Journal of Urology, Vol.31, No.5, pp. 11977-11985, 2024

    Abstract Introduction: Niraparib, a PARP1/2 inhibitor, is newly approved in combination with abiraterone acetate (AA) plus prednisone or prednisolone (niraparib/AA+P) for the treatment of adult patients with BRCA-mutated, treatment-naïve metastatic castration resistant prostate cancer (mCRPC). Detailed guidance beyond the prescribing information may be helpful in managing the side effect profile and dosing practicalities of this combination therapy.
    Materials and methods: A panel of specialists convened to design management algorithms for four common niraparib/ AA+P treatment-related adverse events (AEs) in mCRPC; anemia, thrombocytopenia, hypertension, and nausea. The algorithms build on Health Canada-approved prescribing information to highlight practical considerations related… More >

  • Open Access

    ARTICLE

    Efficacy of Intravenous Treprostinil in High-Risk Single Ventricle Patients Undergoing Glenn Procedure

    Xiaofeng Wang1,#, Xingwei Chen2,#, Shilin Wang1, Xia Li1, Zhongyuan Lu1, Wenlong Wang1, Xu Wang1,*

    Congenital Heart Disease, Vol.19, No.5, pp. 489-498, 2024, DOI:10.32604/chd.2024.054441 - 31 December 2024

    Abstract Objective: Pulmonary hypertension is a crucial factor affecting the recovery after Glenn procedure. This study explores the effects of intravenous treprostinil on hemodynamic status and hospital postoperative recovery under different administration strategies. Methods: We retrospectively included pediatric patients admitted to Fuwai Hospital from 2019 to 2022 who underwent the Glenn procedure and had intraoperative measurements of mean pulmonary artery pressure (mPAP) >15 mmHg postoperatively. Patients with non-anatomical single ventricle physiology undergoing the Glenn procedure and those requiring postoperative extracorporeal membrane oxygenation were excluded. Due to the standardized use of treprostinil in our center starting in… More >

  • Open Access

    PROCEEDINGS

    High-Rate Multiaxial Behaviour of Electron Beam Melted Ti-6Al-2Sn-4Zr-2Mo: An Experimental Study Using a Novel Tension-Torsion Hopkinson Bar Apparatus

    Yuan Xu1,*, Govind Gour2, Manuela Galati3, Abdollah Saboori3, Antonio Pellegrino4

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.013220

    Abstract The dynamic behaviour of Ti-6Al-2Sn-4Zr-2Mo additively manufactured by electron beam melting (EBM) is presented in this study considering synchronised tension-torsion loading. A bespoke spilt Hopkinson Tension-Torsion bar is used to generate combined tensile and torsional stress pulses that interact simultaneously with a novel specimen geometry. High-speed digital imaging correlation techniques are employed to assess the high-rate deformation and crack propagation of the specimen. The material's dynamic response was analysed across a spectrum of stress states, including uniaxial tension, shear, and combinations of tension and shear at strain rates ranging between 500 s-1 and 2000 s-1. Comparable More >

  • Open Access

    PROCEEDINGS

    Progressive Damage Analysis of 3D Woven Composite SENT Test Using a Ternary Model

    Wushuai Liu1, Wu Xu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.012893

    Abstract It is of great significance for improving the in-plane fracture toughness of 3D woven composite (3DWC) to study the failure mechanism of a single edge notch tension (SENT) test. It requires a relatively high computational cost to establish the SENT model based on conformal modeling method. A SENT is established using a proposed ternary model. The matrix cracking, yarn rupture, and debonding at the yarn/matrix interface are involved in the ternary model. Based on the developed SENT model, the progressive damage initiation and evolution of 3DWC SENT are predicted. The load-displacement curves and damage of More >

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