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  • Open Access

    REVIEW

    The regulatory role of ZFAS1/miRNAs/mRNAs axis in cancer: a systematic review

    RAHUL KUMAR SINGH1,#, SUROJIT MANDAL1,#, ADRIJA MOHANTA1, RITU YADAV1, RAJIV RANJAN KUMAR1, RINKU KHATKAR1, VIVEK UTTAM1, UTTAM SHARMA1, MANJIT KAUR RANA2, MANJU JAIN3, HARDEEP SINGH TULI4, AKLANK JAIN1,*

    Oncology Research, Vol.33, No.3, pp. 591-604, 2025, DOI:10.32604/or.2024.050548 - 28 February 2025

    Abstract Objectives: Recently, we and others have demonstrated the involvement of Zinc Finger Antisense 1 (ZFAS1) in cancer development. However, the intricate interplay of ZFAS1 with miRNAs and mRNAs remains to be fully understood. Materials and methods: We followed PRISMA guidelines to retrieve and assess the available literature on the topic “ZFAS1/miRNA/mRNA axis” and “Cancer” from databases such as PubMed, Google Scholar, and ScienceDirect. We also used bioinformatic webtools for analyzing the potential miRNA targets of ZFAS1 and its role in survival of cancer patients along with their role in various biological functions and pathways. Results: Our literature search… More >

  • Open Access

    ARTICLE

    Ketogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination

    TANVI VIJAY GUJARAN1,#, VIGNESH BALAJI EASWARAN1,#, RUNALI SANKHE1, PUGAZHANDHI BAKTHAVATCHALAM2,3, HERMAN SUNIL DSOUZA4, K. SREEDHARA RANGANATH PAI1,*

    Oncology Research, Vol.33, No.2, pp. 381-395, 2025, DOI:10.32604/or.2024.049538 - 16 January 2025

    Abstract Background: To date, there is no effective cure for the highly malignant brain tumor glioblastoma (GBM). GBM is the most common, aggressive central nervous system tumor (CNS). It commonly originates in glial cells such as microglia, oligodendroglia, astrocytes, or subpopulations of cancer stem cells (CSCs). Glucose plays an important role in the, which energy metabolism of normal and cancer cells, but cancer cells exhibit an increased demand for glucose is required for their differentiation and proliferation. The main aim of this study is to explore the anti-cancer efficacy of the ketogenic diet against GBM. Also,… More >

  • Open Access

    CORRECTION

    CORRECTION: Ameliorative effects of melatonin and zinc oxide nanoparticles treatment against adverse effects of busulfan induced infertility in male albino mice

    AMOURA M. ABOU-EL-NAGA1, SHAKER A. MOUSA2, FAYEZ ALTHOBAITI3, EMAN FAYAD3,*, ENGY S. FAHIM1

    BIOCELL, Vol.48, No.12, pp. 1835-1837, 2024, DOI:10.32604/biocell.2024.054569 - 30 December 2024

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Response of the Ginseng C2H2-Type Zinc Finger Protein Family PgZFPs Gene to Methyl Jasmonate Regulation

    Yue Jiang1,2,#, Lingyu Liu1,#, Kangyu Wang1,2, Mingzhu Zhao1,2, Ping Chen1,2, Jun Lei1,2, Yanfang Wang3, Meiping Zhang1,2, Yi Wang1,2,*, Guang Chen1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 3055-3071, 2024, DOI:10.32604/phyton.2024.056384 - 30 November 2024

    Abstract The main active components of ginseng are ginsenosides, which play significant roles in treating cardiovascular diseases, cancer, and providing antioxidant effects. Ginsenosides are primarily synthesized through the mevalonate pathway and the methylerythritol phosphate pathway. Many key enzyme genes involved in this biosynthetic process have been cloned and validated, yet the regulatory functions of transcription factors remain unclear. The C2H2-type zinc finger protein family, one of the largest families of transcription factors, is crucial in plant growth and development, response to biotic and abiotic stresses, and regulation of secondary metabolism. This study, based on the ginseng transcriptome More >

  • Open Access

    ARTICLE

    Critical Concentration of Zinc for Increasing Production and Quality of Mangosteen Fruit in West Sumatera, Indonesia

    Martias1, Dewi Fatria2, Adha Fatmah Siregar2, Raden Heru Praptana3,*, Antonius Kasno3, Muhammad Prama Yufdy4, Riska4, Ni Luh Putu Indriyani4, Affandi4, Tri Budiyanti4, Sri Hadiati4, Ellina Mansyah4, Irwan Muas4, Jumjunidang4, Mizu Istianto4, Djoko Mulyono4, Intan Gilang Cempaka4, Triyani Dewi4, Agus Supriyo3, Bambang Nuryanto3

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 2767-2786, 2024, DOI:10.32604/phyton.2024.055686 - 30 November 2024

    Abstract West Sumatera is one of the largest mangosteen production centers in Indonesia. After the 2019 harvest season, there were variations in fruit production and quality which indicated symptoms of zinc (Zn) deficiency. This study evaluates the status of Zn for increasing the production and quality of mangosteen fruit Ratu Kamang cv. The study was conducting using the observation method in Lima Puluh Kota, West Sumatera from January to December 2020. This study used ten mangosteen trees aged 23 years in three locations selected purposively. Parameters observed included soil properties, leaf nutrients, number of fruits; fruit,… More >

  • Open Access

    PROCEEDINGS

    Ultrasound Overcomes Dendrite Puncture in Aqueous Zinc Batteries

    Fenghui Wang1,*, Hongye Zhang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.012441

    Abstract Aqueous zinc batteries have attracted wide interest due to the high safety of the non-flammable electrolyte. However, the inhomogeneous metal plating during the charging and discharging process generates uncontrollable dendrite growth on the anode surface, which seriously threatens the performance and lifetime of the battery. Herein, we provide a physical method to fragment zinc dendrites by using ultrasound to induce cavitation effects in the electrolyte, which can effectively improve the dielectric structure defects inside the battery and reduce the risk of short circuit. The experimental results show that the roughness and height of zinc deposits More >

  • Open Access

    RETRACTION

    Retraction: long noncoding RNA CAT104 promotes cell viability, migration, and invasion in gastric carcinoma cells through activation of microRNA-381-inhibiting zinc finger e-box-binding homeobox 1 (ZEB1) expression

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.11, pp. 1821-1821, 2024, DOI:10.32604/or.2024.056895 - 16 October 2024

    Abstract This article has no abstract. More >

  • Open Access

    SHORT COMMUNICATION

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

    Song Lu1, Jianjun Guo2, Richard Ansah Herman1, Xinyi Wu1, Lin Ma1, Guohua Wu1,*

    Journal of Renewable Materials, Vol.12, No.6, pp. 1043-1055, 2024, DOI:10.32604/jrm.2024.051767 - 02 August 2024

    Abstract Silk is widely used in the production of high-quality textiles. At the same time, the amount of silk textiles no longer in use and discarded is increasing, resulting in significant waste and pollution. This issue is of great concern in many countries where silk is used. Hydrogen peroxide as a naturally occurring compound is an important indicator of detection in both biology and the environment. This study aims to develop a composite fiber with hydrogen peroxide-sensing properties using discarded silk materials. To achieve this goal, firstly, polydopamine (PDA) was used to encapsulate the ZnFeO NPs… More > Graphic Abstract

    Preparation of Regenerated Silk Fibroin Hybrid Fibers with Hydrogen Peroxide Sensing Properties by Wet Spinning

  • Open Access

    ARTICLE

    Physiological and Biochemical Responses of Perennial Ryegrass Mixed Planting with Legumes under Heavy Metal Pollution

    Yi Xi, Li Zhang, Yanhong Xu, Wei Cheng, Chao Chen*

    Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1749-1765, 2024, DOI:10.32604/phyton.2024.051793 - 30 July 2024

    Abstract In artificially controlled pot experiments, perennial ryegrass was mixed with other leguminous plants (white clover and alfalfa) and treated with lead, zinc and cadmium (337 mg·kg, 648 mg·kg, and 9 mg·kg, respectively) to simulate compound pollution conditions. The results showed that the concentrations of heavy metals, transport factors, and bioconcentration factors in mixed planting of ryegrass decreased compared with those in monoculture. Regardless of whether heavy metal pollution was introduced, mixed planting increased the aboveground and underground biomasses of ryegrass. The different mixed planting treatments had no significant impact on the chlorophyll concentration of ryegrass.… More >

  • Open Access

    ARTICLE

    Synergism of Zinc Oxide/Organoclay-Loaded Poly(lactic acid) Hybrid Nanocomposite Plasticized by Triacetin for Sustainable Active Food Packaging

    Ponusa Songtipya1,2,*, Thummanoon Prodpran1,2, Ladawan Songtipya1,2, Theerarat Sengsuk1

    Journal of Renewable Materials, Vol.12, No.5, pp. 951-967, 2024, DOI:10.32604/jrm.2024.049068 - 17 July 2024

    Abstract The synergistic effect of organoclay (OC) and zinc oxide (ZnO) nanoparticles on the crucial properties of poly(lactic acid) (PLA) nanocomposite films was systematically investigated herein. After their incorporation into PLA via the solvent casting technique, the water vapor barrier property of the PLA/OC/ZnO film improved by a maximum of 86% compared to the neat PLA film without the deterioration of Young’s modulus or the tensile strength. Moreover, the film’s self-antibacterial activity against foodborne pathogens, including gram-negative (Escherichia coli, E. coli) and gram-positive (Staphylococcus aureus, S. aureus) bacteria, was enhanced by a maximum of approximately 98–99% compared to the neat… More > Graphic Abstract

    Synergism of Zinc Oxide/Organoclay-Loaded Poly(lactic acid) Hybrid Nanocomposite Plasticized by Triacetin for Sustainable Active Food Packaging

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