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  • Open Access

    ARTICLE

    PCA-LSTM: An Impulsive Ground-Shaking Identification Method Based on Combined Deep Learning

    Yizhao Wang*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3029-3045, 2024, DOI:10.32604/cmes.2024.046270 - 11 March 2024

    Abstract Near-fault impulsive ground-shaking is highly destructive to engineering structures, so its accurate identification ground-shaking is a top priority in the engineering field. However, due to the lack of a comprehensive consideration of the ground-shaking characteristics in traditional methods, the generalization and accuracy of the identification process are low. To address these problems, an impulsive ground-shaking identification method combined with deep learning named PCA-LSTM is proposed. Firstly, ground-shaking characteristics were analyzed and ground-shaking the data was annotated using Baker’s method. Secondly, the Principal Component Analysis (PCA) method was used to extract the most relevant features related More >

  • Open Access

    ARTICLE

    Comprehensive Evaluation of Distributed PV Grid-Connected Based on Combined Weighting Weights and TOPSIS-RSR Method

    Yue Yang1, Jiarui Zheng1, Long Cheng1,*, Yongnan Zhu2, Hao Wu2

    Energy Engineering, Vol.121, No.3, pp. 703-728, 2024, DOI:10.32604/ee.2023.044721 - 27 February 2024

    Abstract To effectively quantify the impact of distributed photovoltaic (PV) access on the distribution network, this paper proposes a comprehensive evaluation method of distributed PV grid connection combining subjective and objective combination of assignment and technique for order preference by similarity to an ideal solution (TOPSIS)—rank sum ratio (RSR) (TOPSIS-RSR) method. Based on the traditional distribution network evaluation system, a comprehensive evaluation system has been constructed. It fully considers the new development requirements of distributed PV access on the environmental friendliness and absorptive capacity of the distribution grid and comprehensively reflects the impact of distributed PV… More >

  • Open Access

    ARTICLE

    Smart Colorimetric Corn Starch Films Combined with Anthocyanin-Loaded Glutenin-Carboxymethyl Chitosan Nanocomplexes for Freshness Monitoring of Chilled Pork

    Juan Yan1, Wenchao Li1, Xianfang Zhang1, Shisheng Liu2,*

    Journal of Renewable Materials, Vol.12, No.1, pp. 71-87, 2024, DOI:10.32604/jrm.2023.028927 - 23 January 2024

    Abstract In this study, intelligent, pH-responsive colorimetric films were prepared by encapsulating anthocyanins in nanocomplexes prepared from glutenin and carboxymethyl chitosan. These nanocomplexes were added to a corn starch matrix and used in the freshness monitoring of chilled pork. The effects of anthocyanin-loaded nanocomplexes on the physical, structural, and functional characteristics of the films were investigated. The addition of anthocyanin-loaded nanocomplexes increased the tensile strength, elongation at break, hydrophobicity, and light transmittance of the films while decreasing their water vapor permeability. This is because new hydrogen bonds are formed between the film components, resulting in a More >

  • Open Access

    ARTICLE

    Numerical Investigation of Combined Production of Natural Gas Hydrate and Conventional Gas

    Hongzhi Xu1,2, Jian Wang1,3, Shuxia Li1,*, Fengrui Zhao1, Chengwen Wang1, Yang Guo1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.3, pp. 505-523, 2024, DOI:10.32604/fdmp.2023.030604 - 12 January 2024

    Abstract Natural gas hydrate (NGH) is generally produced and accumulated together with the underlying conventional gas. Therefore, optimizing the production technology of these two gases should be seen as a relevant way to effectively reduce the exploitation cost of the gas hydrate. In this study, three types of models accounting for the coexistence of these gases are considered. Type A considers the upper hydrate-bearing layer (HBL) adjacent to the lower conventional gas layer (CGL); with the Type B a permeable interlayer exists between the upper HBL and the lower CGL; with the type C there is… More >

  • Open Access

    ARTICLE

    A Subdivision-Based Combined Shape and Topology Optimization in Acoustics

    Chuang Lu1, Leilei Chen2,3, Jinling Luo4, Haibo Chen1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 847-872, 2024, DOI:10.32604/cmes.2023.044446 - 30 December 2023

    Abstract We propose a combined shape and topology optimization approach in this research for 3D acoustics by using the isogeometric boundary element method with subdivision surfaces. The existing structural optimization methods mainly contain shape and topology schemes, with the former changing the surface geometric profile of the structure and the latter changing the material distribution topology or hole topology of the structure. In the present acoustic performance optimization, the coordinates of the control points in the subdivision surfaces fine mesh are selected as the shape design parameters of the structure, the artificial density of the sound… More >

  • Open Access

    ARTICLE

    Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP prostate cancer cells

    ROGHAYEH GHORBANI1, MAHMOUD GHARBAVI2, ALI SHARAFI3,4, ELHAM RISMANI5, HAMED REZAEEJAM6, YOUSEF MORTAZAVI1,*, BEHROOZ JOHARI3,*

    Oncology Research, Vol.32, No.1, pp. 101-125, 2024, DOI:10.32604/or.2023.044741 - 15 November 2023

    Abstract In the present study, we investigated the synergistic effects of targeted methotrexate-selenium nanostructure containing Myc decoy oligodeoxynucleotides along with X-irradiation exposure as a combination therapy on LNCaP prostate cancer cells. Myc decoy ODNs were designed based on the promoter of Bcl-2 gene and analyzed by molecular docking and molecular dynamics assays. ODNs were loaded on the synthesized Se@BSA@Chi-MTX nanostructure. The physicochemical characteristics of nanostructures were determined by FTIR, DLS, UV-vis, TEM, EDX, in vitro release, and hemolysis tests. Subsequently, the cytotoxicity properties of them with and without X-irradiation were investigated by uptake, MTT, cell cycle, apoptosis, and… More > Graphic Abstract

    Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP prostate cancer cells

  • Open Access

    ARTICLE

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

    JIE DUAN, AIDONG GU*, WEI CHEN, CHANGHAO CHEN, FANGNAN SONG, FAXI CHEN, FANGFANG JIANG, HUIWEN XING

    BIOCELL, Vol.47, No.12, pp. 2609-2615, 2023, DOI:10.32604/biocell.2023.042472 - 27 December 2023

    Abstract Objective: This study aims to analyze the clinical significance and mechanism of nuclear factor erythroid 2-related factor 2 (NRF2) and glutathione peroxidase 4 (GPX4) in primary hepatic carcinoma (PHC). Methods: The expression of NRF2 and GPX4 in peripheral blood of patients with PHC was determined to analyze the diagnostic value of the two combined for PHC. The prognostic significance of NRF2 and GPX4 was evaluated by 3-year follow-up. Human liver epithelial cells THLE-2 and human hepatocellular carcinoma cells HepG2 were purchased, and the expression of NRF2 and GPX4 in the cells was determined. NRF2 and GPX4… More > Graphic Abstract

    Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis

  • Open Access

    ARTICLE

    Deciphering key genes involved in cisplatin resistance in kidney renal clear cell carcinoma through a combined in silico and in vitro approach

    MUNEEBA MALIK1, MAMOONA MAQBOOL2, TOOBA NISAR3, TAZEEM AKHTER4, JAVED AHMED UJAN5,6, ALANOOD S. ALGARNI7, FAKHRIA A. AL JOUFI8, SULTAN SHAFI K. ALANAZI9, MOHAMMAD HADI ALMOTARED10, MOUNIR M. SALEM BEKHIT11, MUHAMMAD JAMIL12,*

    Oncology Research, Vol.31, No.6, pp. 899-916, 2023, DOI:10.32604/or.2023.030760 - 15 September 2023

    Abstract The low survival rate of Kidney renal clear cell carcinoma (KIRC) patients is largely attributed to cisplatin resistance. Rather than focusing solely on individual proteins, exploring protein-protein interactions could offer greater insight into drug resistance. To this end, a series of in silico and in vitro experiments were conducted to identify hub genes in the intricate network of cisplatin resistance-related genes in KIRC chemotherapy. The genes involved in cisplatin resistance across KIRC were retrieved from the National Center for Biotechnology Information (NCBI) database using search terms as “Kidney renal clear cell carcinoma” and “Cisplatin resistance”. The genes… More >

  • Open Access

    ARTICLE

    Genetic Algorithm Combined with the K-Means Algorithm: A Hybrid Technique for Unsupervised Feature Selection

    Hachemi Bennaceur, Meznah Almutairy, Norah Alhussain*

    Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 2687-2706, 2023, DOI:10.32604/iasc.2023.038723 - 11 September 2023

    Abstract The dimensionality of data is increasing very rapidly, which creates challenges for most of the current mining and learning algorithms, such as large memory requirements and high computational costs. The literature includes much research on feature selection for supervised learning. However, feature selection for unsupervised learning has only recently been studied. Finding the subset of features in unsupervised learning that enhances the performance is challenging since the clusters are indeterminate. This work proposes a hybrid technique for unsupervised feature selection called GAk-MEANS, which combines the genetic algorithm (GA) approach with the classical k-Means algorithm. In… More >

  • Open Access

    PROCEEDINGS

    Self-swimming of a Droplet Induced by Combined Diffusiophoresis and Marangoni Effects

    Yuhang Wang1,2, Gaojin Li1,2,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.2, pp. 1-2, 2023, DOI:10.32604/icces.2023.09895

    Abstract The chemically active droplets, which converts the chemical energy into a localized fluid flow at the interfaces by generating a concentration gradients of surfactant, can realize self-propulsion with complex trajectories and have been widely studied to mimic the swimming behavior of micro-organisms. In reality, the motion of chemically active droplets is influenced by a combination of diffusiophoresis and Marangoni effect under concentration gradients of surfactant. However, the interaction between these two effects has been only studied for a drop under the constraint of the axial-symmetric motion. To understand the hydrodynamics of the unconstraint motion, we… More >

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